| | This journal provides immediate access to some articles. In This Issue Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 1–2. doi: 10.1073/iti0105102.PMCID: PMC544079 Commentary Planting and pruning in the brain: MHC antigens involved in synaptic plasticity? Hartmut Wekerle Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 3–4. Published online 2004 December 27. doi: 10.1073/pnas.0408495101.PMCID: PMC544060 Biography INAUGURAL ARTICLE by a Recently Elected Academy Member: Biography of Joshua R. Sanes Tinsley H. Davis Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 5–7. Published online 2004 December 27. doi: 10.1073/pnas.0408739102.PMCID: PMC544077 Physical Sciences Chemistry On the capturing of low-energy electrons by DNA S. G. Ray, S. S. Daube, and R. Naaman Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 15–19. Published online 2004 December 22. doi: 10.1073/pnas.0407020102.PMCID: PMC544061 Photochemical selectivity in guanine–cytosine base-pair structures Ali Abo-Riziq, Louis Grace, Eyal Nir, Martin Kabelac, Pavel Hobza, and Mattanjah S. de Vries Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 20–23. Published online 2004 December 23. doi: 10.1073/pnas.0408574102.PMCID: PMC544067 Changes in DNA bending induced by restricting nucleotide ring pucker studied by weak alignment NMR spectroscopy Zhengrong Wu, Melissa Maderia, Joseph J. Barchi, Jr, Victor E. Marquez, and Ad Bax Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 24–28. Published online 2004 December 23. doi: 10.1073/pnas.0408498102.PMCID: PMC544063 Biological Sciences Applied Biological Sciences From the Cover: Propagation of an infertile hermaphrodite mouse lacking germ cells by using nuclear transfer and embryonic stem cell technology Sayaka Wakayama, Satoshi Kishigami, Nguyen Van Thuan, Hiroshi Ohta, Takafusa Hikichi, Eiji Mizutani, Ryuzo Yanagimachi, and Teruhiko Wakayama Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 29–33. Published online 2004 December 23. doi: 10.1073/pnas.0408548102.PMCID: PMC544064 SNP detection using peptide nucleic acid probes and conjugated polymers: Applications in neurodegenerative disease identification Brent S. Gaylord, Michelle R. Massie, Stuart C. Feinstein, and Guillermo C. Bazan Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 34–39. Published online 2004 December 23. doi: 10.1073/pnas.0407578101.PMCID: PMC544065 Antibody buffering of a ligand in vivo Carol E. O'Hear and Jefferson Foote Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 40–44. Published online 2004 December 22. doi: 10.1073/pnas.0405797102.PMCID: PMC544049 Biochemistry On the capturing of low-energy electrons by DNA S. G. Ray, S. S. Daube, and R. Naaman Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 15–19. Published online 2004 December 22. doi: 10.1073/pnas.0407020102.PMCID: PMC544061 The cAMP binding domain: An ancient signaling module Helen M. Berman, Lynn F. Ten Eyck, David S. Goodsell, Nina M. Haste, Alexandr Kornev, and Susan S. Taylor Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 45–50. Published online 2004 December 23. doi: 10.1073/pnas.0408579102.PMCID: PMC544069 The crystal structure of yeast copper thionein: The solution of a long-lasting enigma Vito Calderone, Benedikt Dolderer, Hans-Juergen Hartmann, Hartmut Echner, Claudio Luchinat, Cristina Del Bianco, Stefano Mangani, and Ulrich Weser Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 51–56. Published online 2004 December 21. doi: 10.1073/pnas.0408254101.PMCID: PMC544076 From the Cover: The modular architecture of protein–protein binding interfaces D. Reichmann, O. Rahat, S. Albeck, R. Meged, O. Dym, and G. Schreiber Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 57–62. Published online 2004 December 23. doi: 10.1073/pnas.0407280102.PMCID: PMC544062 HTLV-I Tax directly binds the Cdc20-associated anaphase-promoting complex and activates it ahead of schedule Baoying Liu, Sohee Hong, Zhanyun Tang, Hongtao Yu, and Chou-Zen Giam Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 63–68. Published online 2004 December 27. doi: 10.1073/pnas.0406424101.PMCID: PMC544051 Studies of the properties of human origin recognition complex and its Walker A motif mutants Jennifer Giordano-Coltart, Carol Y. Ying, Jean Gautier, and Jerard Hurwitz Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 69–74. Published online 2004 December 23. doi: 10.1073/pnas.0408690102.PMCID: PMC544074 Sequential multiple functions of the conserved sequence in sequence-specific termination by T7 RNA polymerase Younghee Sohn and Changwon Kang Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 75–80. Published online 2004 December 22. doi: 10.1073/pnas.0406581101.PMCID: PMC544054 Biophysics Studying multiprotein complexes by multisignal sedimentation velocity analytical ultracentrifugation Andrea Balbo, Kenneth H. Minor, Carlos A. Velikovsky, Roy A. Mariuzza, Cynthia B. Peterson, and Peter Schuck Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 81–86. Published online 2004 December 21. doi: 10.1073/pnas.0408399102.PMCID: PMC538923 A speed limit for conformational change of an allosteric membrane protein Sudha Chakrapani and Anthony Auerbach Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 87–92. Published online 2004 December 23. doi: 10.1073/pnas.0406777102.PMCID: PMC544059 Cell Biology Bone morphogenetic protein (BMP) signaling controls hair pigmentation by means of cross-talk with the melanocortin receptor-1 pathway Andrey A. Sharov, Michael Fessing, Ruzanna Atoyan, Tatyana Y. Sharova, Carrie Haskell-Luevano, Lorin Weiner, Keiko Funa, Janice L. Brissette, Barbara A. Gilchrest, and Vladimir A. Botchkarev Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 93–98. Published online 2004 December 23. doi: 10.1073/pnas.0408455102.PMCID: PMC544050 Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury Sarah L. Pull, Jason M. Doherty, Jason C. Mills, Jeffrey I. Gordon, and Thaddeus S. Stappenbeck Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 99–104. Published online 2004 December 22. doi: 10.1073/pnas.0405979102.PMCID: PMC544052 Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum Scott A. Oakes, Luca Scorrano, Joseph T. Opferman, Michael C. Bassik, Mari Nishino, Tullio Pozzan, and Stanley J. Korsmeyer Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 105–110. Published online 2004 December 21. doi: 10.1073/pnas.0408352102.PMCID: PMC544078 Endometrial cancer is a receptor-mediated target for Mullerian Inhibiting Substance Elizabeth J. Renaud, David T. MacLaughlin, Esther Oliva, Bo R. Rueda, and Patricia K. Donahoe Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 111–116. Published online 2004 December 23. doi: 10.1073/pnas.0407772101.PMCID: PMC544070 S-nitrosoprotein formation and localization in endothelial cells Yi Yang and Joseph Loscalzo Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 117–122. Published online 2004 December 23. doi: 10.1073/pnas.0405989102.PMCID: PMC544053 Rapid biogenesis and sensitization of secretory lysosomes in NK cells mediated by target-cell recognition Dongfang Liu, Liang Xu, Fan Yang, Dongdong Li, Feili Gong, and Tao Xu Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 123–127. Published online 2004 December 23. doi: 10.1073/pnas.0405737102.PMCID: PMC544047 Developmental Biology Microvascular patterning is controlled by fine-tuning the Akt signal Jing Fang Sun, Thuy Phung, Ichiro Shiojima, Terri Felske, J. Nalinee Upalakalin, Dian Feng, Tad Kornaga, Talia Dor, Ann M. Dvorak, Kenneth Walsh, and Laura E. Benjamin Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 128–133. Published online 2004 December 20. doi: 10.1073/pnas.0403198102.PMCID: PMC538747 Characterization of purified intraembryonic hematopoietic stem cells as a tool to define their site of origin Julien Y. Bertrand, Sébastien Giroux, Rachel Golub, Michèle Klaine, Abdelali Jalil, Laurent Boucontet, Isabelle Godin, and Ana Cumano Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 134–139. Published online 2004 December 27. doi: 10.1073/pnas.0402270102.PMCID: PMC544043 Evolution The rate of DNA evolution: Effects of body size and temperature on the molecular clock James F. Gillooly, Andrew P. Allen, Geoffrey B. West, and James H. Brown Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 140–145. Published online 2004 December 23. doi: 10.1073/pnas.0407735101.PMCID: PMC544068 Identification of a nematode chemosensory gene family Nansheng Chen, Shraddha Pai, Zhongying Zhao, Allan Mah, Rebecca Newbury, Robert C. Johnsen, Zeynep Altun, Donald G. Moerman, David L. Baillie, and Lincoln D. Stein Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 146–151. Published online 2004 December 23. doi: 10.1073/pnas.0408307102.PMCID: PMC539308 Genetics From the Cover: RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly to siRNA production Tomoyasu Sugiyama, Hugh Cam, André Verdel, Danesh Moazed, and Shiv I. S. Grewal Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 152–157. Published online 2004 December 22. doi: 10.1073/pnas.0407641102.PMCID: PMC544066 gerbil: Genotype resolution and block identification using likelihood Gad Kimmel and Ron Shamir Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 158–162. Published online 2004 December 22. doi: 10.1073/pnas.0404730102.PMCID: PMC544046 The splicing of yeast mitochondrial group I and group II introns requires a DEAD-box protein with RNA chaperone function Hon-Ren Huang, Claire E. Rowe, Sabine Mohr, Yue Jiang, Alan M. Lambowitz, and Philip S. Perlman Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 163–168. Published online 2004 December 23. doi: 10.1073/pnas.0407896101.PMCID: PMC544071 Immunology The descent of the antibody-based immune system by gradual evolution Jan Klein and Nikolas Nikolaidis Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 169–174. Published online 2004 December 23. doi: 10.1073/pnas.0408480102.PMCID: PMC544055 Medical Sciences Reactive oxygen signaling and MAPK activation distinguish Epstein–Barr Virus (EBV)-positive versus EBV-negative Burkitt's lymphoma Francesca Cerimele, Traci Battle, Rebecca Lynch, David A. Frank, Emma Murad, Cynthia Cohen, Nada Macaron, John Sixbey, Kenneth Smith, Randolph S. Watnick, Aristidis Eliopoulos, Bahig Shehata, and Jack L. Arbiser Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 175–179. Published online 2004 December 20. doi: 10.1073/pnas.0408381102.PMCID: PMC544042 Impaired up-regulation of CD25 on CD4+ T cells in IFN-γ knockout mice is associated with progression of myocarditis to heart failure Marina Afanasyeva, Dimitrios Georgakopoulos, Diego F. Belardi, Djahida Bedja, DeLisa Fairweather, Yan Wang, Ziya Kaya, Kathleen L. Gabrielson, E. Rene Rodriguez, Patrizio Caturegli, David A. Kass, and Noel R. Rose Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 180–185. Published online 2004 December 20. doi: 10.1073/pnas.0408241102.PMCID: PMC544075 Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: Potential therapy for cystic fibrosis Guoshun Wang, Bruce A. Bunnell, Richard G. Painter, Blesilda C. Quiniones, Susan Tom, Nicholas A. Lanson, Jr, Jeffrey L. Spees, Donna Bertucci, Alexandra Peister, Daniel J. Weiss, Vincent G. Valentine, Darwin J. Prockop, and Jay K. Kolls Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 186–191. Published online 2004 December 22. doi: 10.1073/pnas.0406266102.PMCID: PMC544045 Induction of lysosomal membrane permeabilization by compounds that activate p53-independent apoptosis Hamdiye Erdal, Maria Berndtsson, Juan Castro, Ulf Brunk, Maria C. Shoshan, and Stig Linder Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 192–197. Published online 2004 December 23. doi: 10.1073/pnas.0408592102.PMCID: PMC544072 From the Cover: Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal muscles Qi Long Lu, Adam Rabinowitz, Yun Chao Chen, Toshifumi Yokota, HaiFang Yin, Julia Alter, Atif Jadoon, George Bou-Gharios, and Terence Partridge Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 198–203. Published online 2004 December 17. doi: 10.1073/pnas.0406700102.PMCID: PMC544058 Endothelial-specific expression of caveolin-1 impairs microvascular permeability and angiogenesis Philip M. Bauer, Jun Yu, Yan Chen, Reed Hickey, Pascal N. Bernatchez, Robin Looft-Wilson, Yan Huang, Frank Giordano, Radu V. Stan, and William C. Sessa Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 204–209. Published online 2004 December 22. doi: 10.1073/pnas.0406092102.PMCID: PMC544041 Evidence for a p27 tumor suppressive function independent of its role regulating cell proliferation in the prostate David R. Shaffer, Agnes Viale, Ryota Ishiwata, Margaret Leversha, Semra Olgac, Katia Manova, Jaya Satagopan, Howard Scher, and Andrew Koff Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 210–215. Published online 2004 December 22. doi: 10.1073/pnas.0407362102.PMCID: PMC539141 Proteinase-activated receptors 1 and 4 counter-regulate endostatin and VEGF release from human platelets Li Ma, Rafael Perini, Webb McKnight, Michael Dicay, Andre Klein, Morley D. Hollenberg, and John L. Wallace Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 216–220. Published online 2004 December 22. doi: 10.1073/pnas.0406682102.PMCID: PMC544057 Microbiology From the Cover: An unusual signal peptide facilitates late steps in the biogenesis of a bacterial autotransporter Rose L. Szabady, Janine H. Peterson, Kristen M. Skillman, and Harris D. Bernstein Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 221–226. Published online 2004 December 22. doi: 10.1073/pnas.0406055102.PMCID: PMC544056 Neuroscience INAUGURAL ARTICLE by a Recently Elected Academy Member: Gamma protocadherins are required for synaptic development in the spinal cord Joshua A. Weiner, Xiaozhong Wang, Juan Carlos Tapia, and Joshua R. Sanes Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 8–14. Published online 2004 December 1. doi: 10.1073/pnas.0407931101.PMCID: PMC544073 Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy model Bin Zhang, Arpita Maiti, Sharon Shively, Fara Lakhani, Gaye McDonald-Jones, Jennifer Bruce, Edward B. Lee, Sharon X. Xie, Sonali Joyce, Chi Li, Philip M. Toleikis, Virginia M.-Y. Lee, and John Q. Trojanowski Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 227–231. Published online 2004 December 22. doi: 10.1073/pnas.0406361102.PMCID: PMC544048 θ frequency stimulation up-regulates the synaptic strength of the pathway from CA1 to subiculum region of hippocampus Yan-You Huang and Eric R. Kandel Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 232–237. Published online 2004 December 27. doi: 10.1073/pnas.0408368102.PMCID: PMC539311 Bax deletion prevents neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease Roberto Chiesa, Pedro Piccardo, Sara Dossena, Lisa Nowoslawski, Kevin A. Roth, Bernardino Ghetti, and David A. Harris Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 238–243. Published online 2004 December 23. doi: 10.1073/pnas.0406173102.PMCID: PMC544044 Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription Marcus J. Calkins, Rebekah J. Jakel, Delinda A. Johnson, Kaimin Chan, Yuet Wai Kan, and Jeffrey A. Johnson Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 244–249. Published online 2004 December 20. doi: 10.1073/pnas.0408487101.PMCID: PMC538748 |