| | This journal provides immediate access to some articles. Commentaries Three's company when seeking unanimity Karl Sigmund PMCID: PMC539737 The neurotoxicology of hard foraging and fat-melts Caleb E. Finch PMCID: PMC539813 PNAS Classic Article Perspective: Density matters: The semiconservative replication of DNA Philip C. Hanawalt PMCID: PMC539797 Classics: Meselson and Stahl: The art of DNA replication Tinsley H. Davis PMCID: PMC539798 Physical Sciences Applied Mathematics From the Cover:
Win–stay, lose–shift in language learning from peers Frederick A. Matsen and Martin A. Nowak PMCID: PMC539782 Chemistry Structure, initial excited-state relaxation, and energy storage of rhodopsin resolved at the multiconfigurational perturbation theory level Tadeusz Andruniów, Nicolas Ferré, and Massimo Olivucci PMCID: PMC539762 From the Cover:
Long-range oxidative damage to cytosines in duplex DNA Fangwei Shao, Melanie A. O'Neill, and Jacqueline K. Barton PMCID: PMC539793 Measurement of a linear free energy relationship one molecule at a time B. V. Rao, K.-Y. Kwon, A. Liu, and L. Bartels PMCID: PMC539770 Xe NMR lineshapes in channels of peptide molecular crystals Igor Moudrakovski, Dmitriy V. Soldatov, John A. Ripmeester, Devin N. Sears, and Cynthia J. Jameson PMCID: PMC539750 Surface-enhanced Raman scattering on tunable plasmonic nanoparticle substrates J. B. Jackson and N. J. Halas PMCID: PMC539806 From the Cover:
Human myoglobin recognition of oxygen: Dynamics of the energy landscape Yuhong Wang, J. Spencer Baskin, Tianbing Xia, and Ahmed H. Zewail PMCID: PMC539810 Geophysics From the Cover:
Nanoscale waviness of low-angle grain boundaries Craig L. Johnson, Martin J. Hÿtch, and Peter R. Buseck PMCID: PMC539808 Mathematics The topological relationship between the large-scale attributes and local interaction patterns of complex networks A. Vázquez, R. Dobrin, D. Sergi, J.-P. Eckmann, Z. N. Oltvai, and A.-L. Barabási PMCID: PMC539752 Biological Sciences Anthropology Detecting genetic drift versus selection in human evolution Rebecca Rogers Ackermann and James M. Cheverud PMCID: PMC539739 Biochemistry INAUGURAL ARTICLE by a Recently Elected Academy Member: Biography of Philip A. Beachy Melissa Marino PMCID: PMC539818 INAUGURAL ARTICLE by a Recently Elected Academy Member: Extensive phosphorylation of Smoothened in Hedgehog pathway activation Chi Zhang, Elizabeth H. Williams, Yurong Guo, Lawrence Lum, and Philip A. Beachy PMCID: PMC535705 Atomic force microscopic analysis of the binding of the Schizosaccharomyces pombe origin recognition complex and the spOrc4 protein with origin DNA Maria Gaczynska, Pawel A. Osmulski, Yun Jiang, Joon-Kyu Lee, Vladimir Bermudez, and Jerard Hurwitz PMCID: PMC539809 Structure of a proteolytically resistant core from the severe acute respiratory syndrome coronavirus S2 fusion protein Vinit M. Supekar, Chiara Bruckmann, Paolo Ingallinella, Elisabetta Bianchi, Antonello Pessi, and Andrea Carfí PMCID: PMC539766 Vitamin C conjugates of genotoxic lipid peroxidation products: Structural characterization and detection in human plasma John Sowell, Balz Frei, and Jan F. Stevens PMCID: PMC539811 Structures of thymidine kinase 1 of human and mycoplasmic origin Martin Welin, Urszula Kosinska, Nils-Egil Mikkelsen, Cecilia Carnrot, Chunying Zhu, Liya Wang, Staffan Eriksson, Birgitte Munch-Petersen, and Hans Eklund PMCID: PMC539776 Splicing of U12-type introns deposits an exon junction complex competent to induce nonsense-mediated mRNA decay Tetsuro Hirose, Mei-Di Shu, and Joan A. Steitz PMCID: PMC539812 Widespread sulfenic acid formation in tissues in response to hydrogen peroxide Adrian T. Saurin, Hendrik Neubert, Jonathan P. Brennan, and Philip Eaton PMCID: PMC539740 Biophysics Structure, initial excited-state relaxation, and energy storage of rhodopsin resolved at the multiconfigurational perturbation theory level Tadeusz Andruniów, Nicolas Ferré, and Massimo Olivucci PMCID: PMC539762 From the Cover:
Long-range oxidative damage to cytosines in duplex DNA Fangwei Shao, Melanie A. O'Neill, and Jacqueline K. Barton PMCID: PMC539793 Uncovering the hidden ground state of green fluorescent protein John T. M. Kennis, Delmar S. Larsen, Ivo H. M. van Stokkum, Mikas Vengris, Jasper J. van Thor, and Rienk van Grondelle PMCID: PMC539731 The long-range organization of a native photosynthetic membrane Raoul N. Frese, C. Alistair Siebert, Robert A. Niederman, C. Neil Hunter, Cees Otto, and Rienk van Grondelle PMCID: PMC539794 From the Cover:
Human myoglobin recognition of oxygen: Dynamics of the energy landscape Yuhong Wang, J. Spencer Baskin, Tianbing Xia, and Ahmed H. Zewail PMCID: PMC539810 Cell Biology Global network analysis of phenotypic effects: Protein networks and toxicity modulation in Saccharomyces cerevisiae Maya R. Said, Thomas J. Begley, Alan V. Oppenheim, Douglas A. Lauffenburger, and Leona D. Samson PMCID: PMC539745 Human Bub1 protects centromeric sister-chromatid cohesion through Shugoshin during mitosis Zhanyun Tang, Yuxiao Sun, Sara E. Harley, Hui Zou, and Hongtao Yu PMCID: PMC539817 Golgi inheritance in small buds of Saccharomyces cerevisiae is linked to endoplasmic reticulum inheritance Catherine A. Reinke, Patrycja Kozik, and Benjamin S. Glick PMCID: PMC539800 Responses of fibroblasts to anchorage of dorsal extracellular matrix receptors Karen A. Beningo, Micah Dembo, and Yu-li Wang PMCID: PMC539758 Apoptotic and autophagic cell death induced by histone deacetylase inhibitors Yufang Shao, Zhonghua Gao, Paul A. Marks, and Xuejun Jiang PMCID: PMC539807 Developmental Biology Genome sequence of the deep-sea γ-proteobacterium Idiomarina loihiensis reveals amino acid fermentation as a source of carbon and energy Shaobin Hou, Jimmy H. Saw, Kit Shan Lee, Tracey A. Freitas, Claude Belisle, Yutaka Kawarabayasi, Stuart P. Donachie, Alla Pikina, Michael Y. Galperin, Eugene V. Koonin, Kira S. Makarova, Marina V. Omelchenko, Alexander Sorokin, Yuri I. Wolf, Qing X. Li, Young Soo Keum, Sonia Campbell, Judith Denery, Shin-Ichi Aizawa, Satoshi Shibata, Alexander Malahoff, and Maqsudul Alam PMCID: PMC539801 Ecology Ecosystem consequences of bird declines Çağan H. Şekercioğlu, Gretchen C. Daily, and Paul R. Ehrlich PMCID: PMC539768 Enemy-free space maintains swallowtail butterfly host shift Shannon M. Murphy PMCID: PMC539780 Evolution From the Cover:
Win–stay, lose–shift in language learning from peers Frederick A. Matsen and Martin A. Nowak PMCID: PMC539782 Molecular origins of rapid and continuous morphological evolution John W. Fondon, III and Harold R. Garner PMCID: PMC539791 Adaptive evolution of cytochrome c oxidase: Infrastructure for a carnivorous plant radiation Richard W. Jobson, Rasmus Nielsen, Liisa Laakkonen, Mårten Wikström, and Victor A. Albert PMCID: PMC539784 Genetics Genomic dissection of the cell-type-specification circuit in Saccharomyces cerevisiae David J. Galgoczy, Ann Cassidy-Stone, Manuel Llinás, Sean M. O'Rourke, Ira Herskowitz, Joseph L. DeRisi, and Alexander D. Johnson PMCID: PMC535907 Impact of population structure, effective bottleneck time, and allele frequency on linkage disequilibrium maps Weihua Zhang, Andrew Collins, Jane Gibson, William J. Tapper, Sarah Hunt, Panos Deloukas, David R. Bentley, and Newton E. Morton PMCID: PMC539799 Immunology RHAMM, a receptor for hyaluronan-mediated motility, compensates for CD44 in inflamed CD44-knockout mice: A different interpretation of redundancy Shlomo Nedvetzki, Erez Gonen, Nathalie Assayag, Reuven Reich, Richard O. Williams, Robin L. Thurmond, Jing-Feng Huang, Birgit A. Neudecker, Fu-Shang Wang, Eva A. Turley, and David Naor PMCID: PMC539795 Medical Sciences Stimulation of proteoglycan synthesis by glucuronosyltransferase-I gene delivery: A strategy to promote cartilage repair N. Venkatesan, L. Barré, A. Benani, P. Netter, J. Magdalou, S. Fournel-Gigleux, and M. Ouzzine PMCID: PMC535800 Regulation of fibronectin splicing in sinusoidal endothelial cells from normal or injured liver Ming-Ling Chang, Jeng-Chang Chen, Claudio R. Alonso, Alberto R. Kornblihtt, and D. Montgomery Bissell PMCID: PMC539814 TBX21: A functional variant predicts improvement in asthma with the use of inhaled corticosteroids Kelan G. Tantisira, Eun Sook Hwang, Benjamin A. Raby, Eric S. Silverman, Stephen L. Lake, Brent G. Richter, Stanford L. Peng, Jeffrey M. Drazen, Laurie H. Glimcher, and Scott T. Weiss PMCID: PMC539815 Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap Alex Kentsis, Ivan Topisirovic, Biljana Culjkovic, Ling Shao, and Katherine L. B. Borden PMCID: PMC539790 Heterozygosity for Lmna deficiency eliminates the progeria-like phenotypes in Zmpste24-deficient mice Loren G. Fong, Jennifer K. Ng, Margarita Meta, Nathan Coté, Shao H. Yang, Colin L. Stewart, Terry Sullivan, Andrew Burghardt, Sharmila Majumdar, Karen Reue, Martin O. Bergo, and Stephen G. Young PMCID: PMC536056 Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1α/CXC chemokine receptor 4 pathway Jaime Imitola, Khadir Raddassi, Kook In Park, Franz-Josef Mueller, Marta Nieto, Yang D. Teng, Dan Frenkel, Jianxue Li, Richard L. Sidman, Christopher A. Walsh, Evan Y. Snyder, and Samia J. Khoury PMCID: PMC536055 Estrogen mediates Aurora-A overexpression, centrosome amplification, chromosomal instability, and breast cancer in female ACI rats Jonathan J. Li, S. John Weroha, Wilma L. Lingle, Dan Papa, Jeffrey L. Salisbury, and Sara Antonia Li PMCID: PMC539804 From the Cover:
Functional assembly of engineered myocardium by electrical stimulation of cardiac myocytes cultured on scaffolds Milica Radisic, Hyoungshin Park, Helen Shing, Thomas Consi, Frederick J. Schoen, Robert Langer, Lisa E. Freed, and Gordana Vunjak-Novakovic PMCID: PMC539727 Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I Vishram Kedar, Holly McDonough, Ranjana Arya, Hui-Hua Li, Howard A. Rockman, and Cam Patterson PMCID: PMC539735 Regulation of inducible nitric oxide synthase by rapid cellular turnover and cotranslational down-regulation by dimerization inhibitors Pawel J. Kolodziejski, Ja-Seok Koo, and N. Tony Eissa PMCID: PMC539786 Gene expression profiles of epithelial cells microscopically isolated from a breast-invasive ductal carcinoma and a nodal metastasis I. Zucchi, E. Mento, V. A. Kuznetsov, M. Scotti, V. Valsecchi, B. Simionati, E. Vicinanza, G. Valle, S. Pilotti, R. Reinbold, P. Vezzoni, A. Albertini, and R. Dulbecco PMCID: PMC539802 Microbiology Influenza virus entry and infection require host cell N-linked glycoprotein Victor C. Chu and Gary R. Whittaker PMCID: PMC535801 An ecological approach to preventing human infection: Vaccinating wild mouse reservoirs intervenes in the Lyme disease cycle Jean I. Tsao, J. Timothy Wootton, Jonas Bunikis, Maria Gabriela Luna, Durland Fish, and Alan G. Barbour PMCID: PMC536054 The UL41 protein of herpes simplex virus mediates selective stabilization or degradation of cellular mRNAs Audrey Esclatine, Brunella Taddeo, and Bernard Roizman PMCID: PMC539803 Neuroscience Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease Navin Maswood, Jennifer Young, Edward Tilmont, Zhiming Zhang, Don M. Gash, Greg A. Gerhardt, Richard Grondin, George S. Roth, Julie Mattison, Mark A. Lane, Richard E. Carson, Robert M. Cohen, Peter R. Mouton, Christopher Quigley, Mark P. Mattson, and Donald K. Ingram PMCID: PMC539733 Juvenile zebra finches can use multiple strategies to learn the same song Wan-chun Liu, Timothy J. Gardner, and Fernando Nottebohm PMCID: PMC539774 Self-referential phase reset based on inferior olive oscillator dynamics V. B. Kazantsev, V. I. Nekorkin, V. I. Makarenko, and R. Llinás PMCID: PMC535908 14-3-3 γ associates with muscle specific kinase and regulates synaptic gene transcription at vertebrate neuromuscular synapse Laure Strochlic, Annie Cartaud, Alexandre Mejat, Régis Grailhe, Laurent Schaeffer, Jean-Pierre Changeux, and Jean Cartaud PMCID: PMC539788 Lack of delta waves and sleep disturbances during non-rapid eye movement sleep in mice lacking α1G-subunit of T-type calcium channels Jungryun Lee, Daesoo Kim, and Hee-Sup Shin PMCID: PMC539778 Neurofibromatosis 2 (NF2) tumor suppressor merlin inhibits phosphatidylinositol 3-kinase through binding to PIKE-L Rong Rong, Xiaoling Tang, David H. Gutmann, and Keqiang Ye PMCID: PMC535703 Lentivirus-based genetic manipulations of cortical neurons and their optical and electrophysiological monitoring in vivo Tanjew Dittgen, Axel Nimmerjahn, Shoji Komai, Pawel Licznerski, Jack Waters, Troy W. Margrie, Fritjof Helmchen, Winfried Denk, Michael Brecht, and Pavel Osten PMCID: PMC539748 N-ethylmaleimide-sensitive factor is required for the synaptic incorporation and removal of AMPA receptors during cerebellar long-term depression Jordan P. Steinberg, Richard L. Huganir, and David J. Linden PMCID: PMC539805 Pharmacology Essential role for smooth muscle BK channels in alcohol-induced cerebrovascular constriction Pengchong Liu, Qi Xi, Abu Ahmed, Jonathan H. Jaggar, and Alejandro M. Dopico PMCID: PMC539764 Physiology Endogenous circadian rhythm in an index of cardiac vulnerability independent of changes in behavior Kun Hu, Plamen Ch. Ivanov, Michael F. Hilton, Zhi Chen, R. Timothy Ayers, H. Eugene Stanley, and Steven A. Shea PMCID: PMC539796 Plant Biology Identification of a SulP-type bicarbonate transporter in marine cyanobacteria G. Dean Price, Fiona J. Woodger, Murray R. Badger, Susan M. Howitt, and Loraine Tucker PMCID: PMC539743 Populations of photoinactivated photosystem II reaction centers characterized by chlorophyll a fluorescence lifetime in vivo Shizue Matsubara and Wah Soon Chow PMCID: PMC539729 Chromosomal locus rearrangements are a rapid response to formation of the allotetraploid Arabidopsis suecica genome Olga Pontes, Nuno Neves, Manuela Silva, Michelle S. Lewis, Andreas Madlung, Luca Comai, Wanda Viegas, and Craig S. Pikaard PMCID: PMC539792 Population Biology Emergent trade-offs and selection for outbreak frequency in spatial epidemics W. Marijn van Ballegooijen and Maarten C. Boerlijst PMCID: PMC539754 Psychology The primary visual cortex fills in color Yuka Sasaki and Takeo Watanabe PMCID: PMC539772 Social Sciences Anthropology The coevolution of ritual and society: New 14C dates from ancient Mexico Joyce Marcus and Kent V. Flannery PMCID: PMC539816 Corrections Proc Natl Acad Sci U S A. 2004 December 28; 101(52): 18262. doi: 10.1073/pnas.0409058101.PMCID: PMC539819 Corrects: Claudio Napoli, et al. Long-term combined beneficial effects of physical training and metabolic treatment on atherosclerosis in hypercholesterolemic mice. Proc Natl Acad Sci U S A. 2004 June 8; 101(23): 8797–8802. Proc Natl Acad Sci U S A. 2004 December 28; 101(52): 18262. doi: 10.1073/pnas.0409060101.PMCID: PMC539820 Corrects: Filomena de Nigris, et al. From the Cover:
Beneficial effects of antioxidants and l-arginine on oxidation-sensitive gene expression and endothelial NO synthase activity at sites of disturbed shear stress. Proc Natl Acad Sci U S A. 2003 February 4; 100(3): 1420–1425. Proc Natl Acad Sci U S A. 2004 December 28; 101(52): 18262. doi: 10.1073/pnas.0409068101.PMCID: PMC539821 Corrects: John P. Cooke. Flow, NO, and atherogenesis. Proc Natl Acad Sci U S A. 2003 February 4; 100(3): 768–770. |
