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Beby Jayaram, Ph.D.

Program Operations Branch

Beby Jayaram, Ph.D.
Beby Jayaram, Ph.D.
Chemist



Tel (919) 541-1480
Fax (919) 541-3687
jayaram1@niehs.nih.gov

P.O. Box 12233
Mail Drop K2-07
Research Triangle Park, North Carolina 27709
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Beby Jayaram, Ph.D., is a chemist and serves as a project officer for an analytical chemistry contract in the Program Operations Branch of NTP. Jayaram oversees and directs the activities of analytical chemistry projects to provide materials for study, formulation methods, and methods of analysis of formulations and biological samples, and ensures that reports of these efforts are complete and accurate. He also provides timely responses to chemistry problems as they develop at the study laboratory and serves as a resource for NTP Project Leaders designing new studies.

Prior to joining the NTP in 2003, Jayaram worked in a variety of research areas such as physical organic chemistry, analytical chemistry, synthetic chemistry and biochemistry. He studied the kinetics and oxidation reaction mechanisms of pharmaceuticals by organic halogenated amines. He was involved in the production of monoclonal antibodies and peptides, performed the synthesis of organic compounds and biomolecules, and purified proteins from various samples using a variety of techniques. As a patent examiner, Jayaram reviewed patent applications for their quality and patentability of pharmaceutical compounds, compositions, process of preparation and methods of use and approved qualified patent applications.

Jayaram received his B.S. in chemistry and physics 1974, as well as a M.S. in chemistry from Mysore University in 1976. He received a Ph.D., specializing in physical organic Chemistry from Mysore University in 1985. He was a postdoctoral fellow at Baylor University in Texas and the University of Kentucky from 1988–94.

Selected Publications

  1. McGuire, M; Carroll, L.J; Thrall, S.H; Mariano, D.D ; Jayaram, B., Haley, B.E., Thrall, S.H. Determination of the Nucleotide Binding Site within Clostridum symbiosum Pyruvate Phosphate Dikinase by Photoaffinity Labelings, Site-Directed Mutagenesis, and Structural Analysis. Biochemistry. 35, 8544 (1996) [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/8679615?ordinalpos=26&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum) Exit NIEHS
  2. Jayaram, B., and Haley, B.E. Identification of Peptides within the Base Binding Domains of the GTP- and ATP- specific Binding Sites of Tubulin. J. Biol. Chem. 269, 3233 (1994) [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/8106359?ordinalpos=31&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum) Exit NIEHS
  3. Jayaram, B., and Madegowda, N.M. Assay of D-Cycloserine by Chloramine-B, Bromamine-T and Bromamine-B. Anal. Chem. Acta. 173, 381 (1985)
  4. Jayaram, B., and Mayanna, S. M. Kinetics and Mechanism of Oxidation of Pyridoxine by Sodium N-chloro Benzene sulfonamide. Bull. Chem. Soc. Japan. 57, 1439 (1984)
  5. Jayaram, B., and Mayanna, S. M. Determination of Caffeine using Sodium N-chloro p-Toluene sulfonamide. The Analyst 106, 729 (1981)

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Last Reviewed: February 12, 2009