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About the NCL
Mission - Cancer Nanotechnology Plan - Management & Administration Staff - Facilities - Career Opportunities Staff
Scott E. McNeil, Ph.D., Director
Martin Fritts, Ph.D., Senior Principal Scientist
Anil K. Patri, Ph.D., Deputy Director Dr. Patri received his B.Sc., from Osmania University and M.Sc., in organic chemistry from Aligarh Muslim University, India. He then worked for two years as a lecturer in chemistry in India and then obtained his Ph.D. in organic chemistry from the University of South Florida under the guidance of Prof. George Newkome. After a one-year post-doctoral training with Dr. Donald Tomalia at the University of Michigan, he joined the Center for Biologic Nanotechnology as a staff scientist. In this position, he developed dendrimer based nanomaterial for targeting, imaging and drug delivery applications.
Nick Panaro, Ph.D., Senior Scientist Prior to joining NCL, Nick conducted postdoctoral research at the University of Pennsylvania, where he focused on the design and fabrication of microelectromechanical systems for genetic analysis and development of nylon nanostructures for clinical assays. Dr. Panaro was also a postdoctoral fellow at NCI where his research focused on tumor angiogenesis. He holds a B.S. degree in chemical engineering from Drexel University and a Ph.D. in chemical engineering from the Rice University Biomedical Engineering Laboratory. He has extensive laboratory experience in microfluidics, cell and molecular biology, analytical techniques, and tissue engineering. Nick has also worked as a patent examiner at the United States Patent and Trademark Office where his work focused on the evaluation of patent applications in the areas of biosensors, microarrays and nucleic acid technologies.
Prior to joining the NCL, Dr. Stern was a Post-Doctoral Fellow at the University of North Carolina - Chapel Hill in the Division of Drug Delivery and Disposition and Curriculum in Toxicology. In this position, his research focused on examining the role of intestinal metabolism in modulating the gastrointestinal toxicity of chemotherapeutic agents. His areas of expertise include biochemical toxicology of the liver and kidney, analytical methodology and drug metabolism/pharmacokinetics. He received his B.S. degree in biochemistry from the University of Rochester, Rochester, NY and his Ph.D. in toxicology from the University of Connecticut at Storrs, CT.
Marina Dobrovolskaia, Ph.D., Scientist Prior to joining the NCL, Dr. Dobrovolskaia worked as a Research Scientist; Department of Immunochemistry at a GLP operated contract research organization in Richmond, VA. She has been supervising the design, development and validation of bioanalytical ligand-binding assays to support pharmacokinetic and toxicity studies in a variety of drug development projects. Her areas of expertise include cell signaling, innate immunity, immunogenicity and analytical methodology. She received her M.S. degree in biology/microbiology from the Kazan State University in Russia and her Ph.D. in biological sciences from the N.N. Blokhin Cancer Research Center of Russian Academy of Medical Sciences in Moscow, Russia.
Pavan Adiseshaiah, Ph.D., Scientist Prior to joining the NCL, Dr. Adiseshaiah was a scientist at Avalon Pharmaceuticals, Inc., Maryland and was involved in the in vivo pharmacology experiments – preclinical testing of small molecule anticancer drugs, gene expression and protein biomarker and efficacy studies. Dr. Adiseshaiah did his postdoctoral fellowship from the Department of Environmental Health Sciences, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. His research focus at the Johns Hopkins was to elucidate the role of Fos-related antigen 1 (FRA-1) in lung tumorigenesis. His areas of expertise include transcriptional regulation, signal transduction pathways, cell-based functional and biomarker assays, recombinant DNA technology, transgenic mouse model development and in vivo pharmacology studies. He received his M.S degree in life sciences from the University of Hyderabad, India and Ph.D. degree from the Department of Biological Sciences, the National University of Singapore, Singapore.
Jeffrey D. Clogston, Ph.D., Scientist
Dr. Clogston received his B.S. in chemical engineering from Manhattan College and his Ph.D. in chemical engineering from The Ohio State University. His research dissertation was on the application of the lipidic cubic phase for drug delivery, wastewater remediation, and membrane protein crystallization. His areas of expertise include physico-chemical characterization of and in vitro release from lipid-based drug delivery systems, analytical methodology, and protein and lipid biochemistry.
Prior to joining the NCL, he worked as a Postdoctoral on directed assembly of nanoparticles by atomic force microscopy (AFM)-based lithography in Professor Harald Fuchs' group at Muenster University, Germany, and then joined Professor Nadrian Seeman's lab at New York University as a Postdoctoral working on scaffolded assembly of nanoparticles with Branched DNA. Dr. Zheng received his B.S. and M.S. degree in inorganic chemistry from Inner Mongolia University and his Ph.D. in physical chemistry/nanoscience and technology from Peking University, China. His areas of expertise include AFM imaging and lithography, synthesis and modification of nanoparticles as well as design and construction of robust Branched DNA motifs.
Parag Aggarwal, Ph.D., Postdoctoral Fellow Dr. Aggarwal received his B.S. in chemistry from Case Western Reserve University and his Ph.D. in medicinal chemistry from the University of Michigan. His research dissertation was on the validation of the Kdo pathway as a potential antimicrobial target. His areas of expertise include physicochemical characterization, analytical methodology, molecular enzymology, cell biology, and protein biochemistry.
Denise Johnson, Ph.D., Postdoctoral Fellow Denise received her B.S. in chemistry from Shaw University and her Ph.D. in toxicology from the Bloomberg School of Public Health of the Johns Hopkins University. Her research dissertation was on the development of a quantitative mass spectrometric method for determination of the role of aldo-keto reductases in aflatoxin B1 metabolism. Denise’s areas of expertise include analytical methodology, biomarker development, xenobiotic metabolism, and toxicology of the liver.
Harikrishna Devalapally, Ph.D., Postdoctoral Fellow Prior to joining the NCL, he worked as a Postdoctoral Fellow in Professor Mansoor Amiji’s group at Northeastern University, Boston MA. There, he worked on improving efficacy, safety and reversal of multi-drug resistance in ovarian cancer using polymer-based nanoparticles. Dr. Devalapally received his masters of pharmacy and Ph. D in pharmacology from Kakatiya University, India in 2005. His dissertation research was on synthesis, in vitro characterization, pharmacokinetics and biodistribution studies of doxorubicin prodrugs for tumor specific activation. His areas of expertise include in vitro cell based assays, pharmacokinetics, pharmacodynamics and safety studies of targeted drug delivery systems.
Chris McLeland, Senior Research Associate Chris McLeland served as a research biochemist at the Armed Forces Radiobiology Research Institute in Bethesda, MD, on the Biodosimetry Team prior to joining NCL. In this capacity, he and his colleagues developed a quantitative real-time PCR assay for assessing exposure to radiation. He has collaborated with NCI investigators and was subsequently co-authored on peer-reviewed publications. He received his B.S. degree in Biology from the University of South Carolina, Columbia, SC.
Timothy M. Potter, Research Associate Tim began working at the NCI at Frederick in 1989 in the Laboratory Animal Sciences Program. In early 1990, he transferred to the In Vitro Cell Line Screening Program (IVCLSP) of the Screening Technology Branch. In the IVCLSP, he developed extensive cell culture experience as a technician in the 60 cell line human tumor panel, the AIDS-related Lymphoma Screen and the Cellular Differentiation Screen. He was later assigned to the Molecular Target Screening Program, where he helped develop and run a variety of molecular target screens, including the B/ZIP and nucleocapsid screens. The wide range of experiences and responsibilities in his assignments in the Screen Technology Branch has given Tim valuable skills in cell culture and assay development.
Barry W. Neun, Research Associate Barry has been employed continuously at the NCI-FCRF campus since November of 1987. He comes to the NCL having worked in the In Vitro Cell Line Screening Program (IVCLSP), part of the Screening Technologies Branch (STB). He has extensive experience in mammalian cell culture having helped maintain the 60 cell line human tumor panel used in the IVCLSP. He then branched out into high throughput molecular targeted anti-cancer screens. One screen Barry helped develop involved Thymidine Phosphorylase, an enzyme involved in angiogenesis signaling. Working on the development, optimization and implementation of high throughput molecular targeted screens has also given Barry valuable experience in recombinant protein expression and isolation.
Sarah Skoczen, M.S., Research Associate Sarah received a B.S. in biology from Shippensburg University and a M.S. in biotechnology from Johns Hopkins University in December of 2005. She began working at SAIC-Frederick in June of 2002 in the In Vitro Cell line Screening Program (IVCLSP) of the Screening Technology Branch. As a technician on the 60 cell line human tumor panel, she gained valuable experience in mammalian cell culture and aseptic technique. She has also worked in the Radiation Modifiers Evaluation Module (RAMEM), where she screened for radiosensitivity and chemosensitivity of human tumor cell lines.
David Parmiter, Research Associate David received a B.A. in biology from the University of Virginia in 2003, and is currently pursuing a M.S. in biomedical science.
Sonny Man, M.S., Research Associate Sonny received a B.S. in Chemical Biology from the University of California at Berkeley in May 2005 and a M.S. in Chemistry from the University of Illinois at Urbana-Champaign in July 2008. His thesis was on the efficient synthesis of polyglycerol dendrimers by azide-alkyne cycloaddition.
Matthew Hansen, M.S., Research Associate Matt received a B.A. in chemistry from Wabash College in 2004, and a M.S. in chemistry from Purdue University in 2006. While at Purdue, he conducted research on the functionalization and characterization of gold nanorods for development as contrast imaging agents.
Jamie Rodriguez, Research Technician After graduating in December 2005 with a B.S. in biology and a minor in engineering from Shepherd University, she worked as a Senior Research Laboratory Technician for Advanced Product Enterprises (APE), a biotechnology company involved in the identification, testing, development, and production of bimolecular and molecular biology products. At APE Mrs. Rodriguez dealt with the production and purification of recombinant proteins and antibodies using cell culture bioreactors and chromatography methods, respectively. There she also established her aseptic technique and knowledge of mammalian and insect cell culture. Mrs. Rodriguez received a NASA scholarship during her junior and senior years at Shepherd University and has been a member of the Society of Women Engineers since 2005. She enjoys working with youth and has participated in numerous science fairs, judging mostly grade-school-level projects.
Prior to joining SAIC-Frederick, Lisa worked as an executive assistant for over 28 years. She has provided administrative support for one of the largest construction firms in Maryland.
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