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Cancer Trends Progress Report – 2007 Update

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Stage at Diagnosis


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Stage at Diagnosis
 Diagnosis

There are fewer late-stage diagnoses for five major cancers where early detection is either recommended and/or widely used.

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Late-Stage Diagnosis of Cancer

Cancers can be diagnosed at different stages in their development. Stage of cancer diagnosis may be expressed as numbers (I, II, III, or IV, for example) or by terms such as "localized," "regional," and "distant." The lower the number or the more localized the cancer, the better a person's chances of benefiting from treatment and being cured.

Tracking the rates of late stage (distant) cancers is a good way to monitor the impact of cancer screening. When more cancers are detected in early stages, fewer should be detected in late stages.

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Measure

Late-stage diagnosis rate: The number of new cancer cases diagnosed at a late (distant) stage, per 100,000 people per year. This report shows the rates for cancers of the prostate, colon, breast, and cervix uteri.

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Period – 1980–2004

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Trends

Prostate: Rose from 1975–1992, falling for next three years, and stable for 1995–2004. Late-stage prostate cancer rose from 1980–1991 and then has fallen since early 1990s following introduction of the prostate-specific antigen (PSA) test.

Colon: Falling

Female breast: Stable

Rectum: Falling

Cervix: Falling from 1980–1996 and non-significant change from 1996–2004

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Most Recent Estimates

In 2004, five major cancers were diagnosed at a late stage at the following rates:

Prostate: 6.5 new cases per 100,000 men per year

Colon: 6.7 new cases per 100,000 people per year

Female breast: 7.2 new cases per 100,000 women per year

Rectum: 2.0 new cases per 100,000 people per year

Cervix: 0.8 new cases per 100,000 women per year

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Healthy People 2010 Targets

There is no Healthy People 2010 target for this measure.

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Groups at High Risk for Late-Stage Diagnosis

People who do not have regular, recommended cancer screening tests and/or experience a delay in following up on an abnormal screening test finding are at highest risk of being diagnosed with late-stage cancer.

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Key Issues

A lower rate of diagnosis at late stages is an early sign of the effectiveness of cancer screening efforts. These lower rates can be expected to occur before decreases in death rates are seen. For example, the drop in new cases of late-stage prostate cancer probably was an early indicator of lower death rates observed for this disease.

Important differences among racial and ethnic groups in the percentage of cases diagnosed at a late stage contribute to disparities in cancer mortality.

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Additional Information on Stage at Diagnosis

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National Cancer InstituteDepartment of Health and Human ServicesNational Institutes of HealthUSA.gov