1. Gao ZG, Jacobson KA Emerging adenosine receptor agonists. Expert Opin Emerg Drugs(12): 479-92, 2007. [Full Text/Abstract]
2. Jacobson KA, Gao ZG, Liang BT Neoceptors: reengineering GPCRs to recognize tailored ligands. Trends Pharmacol Sci(28): 111-6, 2007. [Full Text/Abstract]
3. Ko H, Fricks I, Ivanov AA, Harden TK, Jacobson KA Structure-activity relationship of uridine 5''-diphosphoglucose analogues as agonists of the human P2Y14 receptor. J Med Chem(50): 2030-9, 2007. [Full Text/Abstract]
4. Koizumi S, Shigemoto-Mogami Y, Nasu-Tada K, Shinozaki Y, Ohsawa K, Tsuda M, Joshi BV, Jacobson KA, Kohsaka S, Inoue K UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis. Nature(446): 1091-5, 2007. [Full Text/Abstract]
5. Jacobson KA, Gao ZG Adenosine receptors as therapeutic targets. Nat Rev Drug Discov (5): 247-64, 2006. [Full Text/Abstract]
6. Jacobson KA, Ohno M, Duong HT, Kim SK, Tchilibon S, C esnek M, Holy A, Gao ZG A Neoceptor Approach to Unraveling Microscopic Interactions between the Human A(2A) Adenosine Receptor and Its Agonists. Chem Biol (12): 237-247, 2005. [Full Text/Abstract]
7. Joshi BV, Moon HR, Fettinger JC, Marquez VE, Jacobson KA A New Synthetic Route to (North)-Methanocarba Nucleosides Designed as A(3) Adenosine Receptor Agonists. J Org Chem (70): 439-447, 2005. [Full Text/Abstract]
8. Gao ZG, Kim SK, Ijzerman AP, Jacobson KA Allosteric modulation of the adenosine family of receptors. Mini Rev Med Chem (5): 545-53, 2005. [Full Text/Abstract]
9. Kim HS Ohno M Xu B Kim HO Choi Y Ji XD Maddileti S Marquez VE Harden TK Jacobson KA 2-Substitution of adenine nucleotide analogues containing a bicyclo[3.1.0]hexane ring system locked in a northern conformation: enhanced potency as P2Y1 receptor antagonists. J Med Chem (46): 4974-87, 2003. [Full Text/Abstract]
10. Jacobson KA Jarvis MF Williams M Purine and pyrimidine (P2) receptors as drug targets. J Med Chem (45): 4057-93, 2002. [Full Text/Abstract]