[ Return To SBIR ]

The information on this site has been provided directly by the SBIR/STTR companies. Its appearance on this web site neither constitutes nor should be inferred to be an endorsement or recommendation by the National Institutes of Health. If you have any questions or comments, please contact Ms. Jo Anne Goodnight, NIH SBIR/STTR Program Coordinator.

Brief profiles of companies that have utilized the programs and effectively commercialized technologies developed under SBIR/STTR are shown below. Click Here to submit your company's success story to NIH for inclusion below. Once reviewed, the information will be added to this list. Submissions of items unrelated to the SBIR/STTR programs will not be accepted. The company name and project title for each Success Story are shown below. (Note: The current sort field is shown in red. Click on column header links to re-sort.)

Company	Project Title	Keywords	City	State
Advanced Brain Monitoring, Inc.	Apnea Risk Evaluation System	sleep apnea, in-home monitoring, pulse-oximetry, sleep disorders, apnea risk questionnaire	Carlsbad	CA
Applied Health Science	Wound and Skin Intelligence System (TM) or WSIS (TM)	Chronic wound, Pressure ulcer, Risk assessment, Pressure Sore Status Tool, WSIS	Seattle	WA
Archimage, Inc.	U44 DK066724-03	serious games, video games, diabetes, obesity, prevention, physical activity, nutrition, children	Houston	TX
ARISIL, Inc.	Non-Surgical Device for Treatment of Middle Ear Effusion	EarPopper, otitis media, middle-ear effusion, eustachian tube, autoinsufflation, Politzer method, manufacturing	Brooklyn	NY
Audiology Incorporated	Automated Hearing Tests	hearing test, pure-tone audiometry, speech recognition, speech audiometry, earphone, audiology	Arden Hills	MN
Behavior Therapy Associates LLP	Brief intervention for alcoholism via computer software	alcohol problems, brief intervention, computer intervention, program evaluation	Albuquerque	NM
Biopsy Sciences	Biodegradable Sealant for Biopsy Tract in Soft Tissue	BioSEAL, CT guided lung biopsy, hydrogel, pneumothorax, FNA	Clearwater	FL
BioSciCon, Inc.	MarkPap(r) Technology for Cervical Cancer Screening	MarkPap test, Cervical cancer, Acid phosphatase, Pap test, Cancer biomarkers, Pap smear, Liquid-based Pap, Cancer screening	Rockville	MD
CardioMend LLC	Stentless semilunar heart valve reconstruction	heart valve, autologous tissue, pericardium, semilunar, tissue testing	Santa Barbara	CA
CasterShoX	Noise Attenuation Tech to Prevent Hearing Loss	Noise Attentuation, Shock Absorption, Noise Induced Hearing Los, Compact, manufacturing	Canton	MI
Celadon Laboratories Inc	Multi-Method Software Platform for Primer and Probe Design	oligonucleotide, assay design, PCR, SNPs, primers, probes, genomics, bioinformatics	Hyattsville	MD
CFD Research Corporation	Development of Improved Hemodialysis Catheter Designs	Catheter, hemodialysis, access recirculation, suction pressure, hemolysis	Huntsville	AL
Clever Sys. Inc.	PhenoScan Series	digital video, lab animal, behaviors, automated analysis	Vienna	VA
Concordant Rater Systems	An Interactive Computer Interview for Mania to Enhance Human Rater Performance	CNS outcomes, Rater Reliability, Clinical Trials, Site Monitoring, Computerized Adaptive Tes, Mental Health, Bipolar Disorder	Boston	MA
Cyma	An Easy-to-Use System for Ambulatory Activity Evaluation	walk, physical activity, ambulatory monitoring, pedometer, StepWatch, SAM, step, instrument	Seattle	WA
dbaza, inc.	INTERACTIVE LEARNING FOR CHILDREN WITH DIABETES	diabetes education, interactive learning, children with diabetes, pediatric diabetes care, diabetes self-management, CD-ROM	Pittsburgh	PA
Decision Systems	COMMUNITY VOICE MAIL FOR ROUTINE AND DISASTER SERVICES	teleminder, communications, disaster relief, computer system	Los Alamos	CA
DeltaNu, LLC	RAPID DETECTION OF PRE-AND NEONATAL METABOLIC DISORDERS	SERS, Raman, Medical Device, Point of Care, Nanotechnology, Miniature Raman, Laramie, Wyoming	Laramie	WY
Echelon Biosciences Inc	Phosphoinositide 3-Kinase Assays in Cancer Diagnosis	Phosphoinositide 3-Kinase, PI 3-K, PI(3,4,5)P3, PI 3-Kinase, PI3K, Echelon	Salt Lake City	UT
EKOS Corporation	In vivo evaluation of ultrasound enhanced lysis.	Ischemic Stroke, PAO, Infusion catheters, flow sensor, therapeutic ultrasound, manufacturing	Bothell	WA
Evening Star Productions	DEVELOPING VIDEO AND PRINT LIBRARY OF LIFE CARE PROGRAMS	health care, life skills, nutrition and diet, exercise and fitness, legal and financial , video series	Akron	OH
Hawaii Biotech, Inc.	Recombinant Vaccine Development and Commercialization	vaccine, recombinant, West Nile, malaria, influenza, dengue	Aiea	HI
Humanitas, Inc.	Web Trials Information Exchange	cancer clinical trials, handheld computers, distance learning, website, document management, proposal management, online meetings	Silver Spring	MD
I.S. Grupe, Inc.	Portable Patient Record	patient record, medical information, electronic storage, portable	Westmont	IL
Illumina, Inc.	Automated DNA Synthesizer Using Tilted Plate Technology	DNA synthesis, automated synthesizer, SNP analysis, genotyping	San Diego	CA
Illumina, Inc.	Randomly Ordered Arrays for SNP Genotyping	polymorphism, SNP, genotyping, genetics, oligonucleotide, fiberoptic, array, multiplex	San Diego	CA
Illumina, Inc.	Decoding Randomly- Assembled DNA Arrays	decoding, bead, random, oligonucleotide, fluorescence, microarray, snp genotyping, gene expression	San Diego	CA
Insight NeuroImaging Systems, LLC (INSL)	Noninvasive Devices for fMRI Studies in Mental Illness	imaging conscious animals, functional MRI, radiofrequency electronic, mental illness, drug discovery, drug addiction, epilepsy	Worcester	MA
Intelligent Optical Systems	Distributed, sensitive chemical and biochemical sensors and sensor networks.	Fiber, Sensors, Distributed, Specific, Biofilms, Real-time, Adaptive, Network	Torrance	CA
Leo Lens Technology	Printing of Digitized Image of Iris for Prosthetic Lens	Digitized Iris Image, Inkjet printing, Prosthetic lens, Antimicrobial, Contact lens, Silicone Hydrogel, Lens dryness, Friction reduction	San Diego	CA
Lexical Technology	Voice Recognition Front-End to Cancer Knowledge Sources	speech interface, voice prompts, dialog, conversational features	Alameda,	CA
LigoCyte Pharmaceuticals	Rational Design of Adhesion Blocking Anti-Inflammatories	chronic inflammation, antibody, adhesion, pulmonary	Bozeman	MT
MBF Bioscience	Neurolucida, AutoNeuron, Stereo Investigator, NeuroInformatica, 3D Virtual Slice	stereology, morphometry, automated analysis, digital image archive, neuron reconstruction	Williston	VT
Menssana Research, Inc	Breath tests for detection of disease	breath, volatile, heart transplant, lung cancer, breast cancer, tuberculosis	Fort Lee	NJ
MIDI, Inc.	Identification of bacteria direct from blood culture	Fatty acid analysis, Bacterial identification, Gas chromatography, Sample preparation, Sensitivity, Speed of identification	Newark	DE
Morphonix™	Journey into the Brain	CD-ROM, Neuroscience, Education, Multimedia, Computer Game	San Rafael	CA
NimbleGen Systems, Inc.	Development of a Maskless Array Synthesizer	microarray, MAS, ChIP chip, CGH, Expression, Manufacture	Madison	WI
OncoMetrics*, Inc.	Precise breast cancer staging with an expert system	breast cancer, dormancy, surgery, angiogenesis, mammography, racial difference , bimodal relapse, chemotherapy	Trumbull	CT
OncoMetrics, Inc.	Precise breast cancer staging with an expert system	angiogenesis, breast cancer, surgery, dormancy	Trumbull	CT
Optiva Corporation	MEDICINE AND DENTIFRICE DISPENSING SONIC BRUSH, SONIC TOOTHBRUSH	SONICARE, SONIC, Power Toothbrush, Cleans Beyond the Bristle	Snoqualmie	WA
Planning Systems Incorporated	Hybrid Adaptive Beamformer (HAB)	array, speech intelligibility, microphone, speech in noise, microphone, beamformer	Reston	VA
PortaScience, Inc.	A Simple Point-of-Care White Blood Cell Count Test	white blood cell, chemotherapy, mastitis, diagnostic, point-of-care, portable	Moorestown	NJ
Pro-Change Behavior Systems, Inc.	A Stress Management Expert System for Cancer Prevention	stress management, Transtheoretical Model, Stage of Change, Population Intervention, Tailored Communications	West Kingston	RI
Ripple Effects	Training and assessment software to reduce risk and enhance protective factors in adolescents	violence prevention, behavior training , software, substance abuse, truancy, adolescent risk factors, school failure, social-emotional skills	San Francisco	CA
SAM Technology, Inc.	MANSCAN® Human Brain Function Research System	human brain function, EEG, evoked potential, MRI, digital signal processing, pattern recognition, bioamplifiers, 3D visualization	San Francisco	CA
SAM Technology, Inc.	IMAGE VUE™ Neurophysiological and Neuroanatomical Visualization and Source Localization Software	medical imaging, human brain, epilepsy, seizure localization, EEG, MRI, 3-D graphics	San Francisco	CA
Samuels & Associates	Food BEAMS: Food and Beverage Environmental Assessment and Monitoring System	Competitive foods, Nutrition, Policy Adherence, Data Collection, Policy Monitoring, Schools, Health	Oakland	CA
Sarawak MediChem Pharmaceuticals, Inc.	SYNTHESIS OF NEW ANTIHIV AGENTS RELATED TO CALANOLIDE A	HIV, Clinical Trials, NNRTI, resistance, in vitro, in vivo, calanolide, natural product	Woodridge	IL
Sierra Scientific Instruments, Inc.	Development of a Motility Visualization System	Manometry, Motility, High-resolution, Gastroenterology, Esophagus, Stomach, Duodenum, Anorectum	Los Angeles	CA
SIGA Technologies, Inc.	Small Molecule Inhibitors of Smallpox Virus Replication	antiviral, smallpox, ST-246, egress inhibitor, biodefense, high throughput screen	Corvallis	OR
Simbex	ActiveStep Fall Prevention Training System	Fall prevention, Fall-risk assessment, Falls in the elderly, Task specific training, Neuromuscular programming, Dynamic gait training, Fall recovery	Lebanon	NH
Simbex	Head Impact Recording Technology for Field Applications	Brain injury, Concussion, Helmet, HIT System, Head impact, Biomechanics, Telemetry, MTBI	Lebanon	NH
Stellar Biotechnologies, Inc.	Technology for Culture of Megathura Crenulata for KLH	KLH, hemocyanin, Megathura, Limpet, cancer, vaccine, aquaculture, immunostimulatory	Port Hueneme	CA
Stereology Resource Center	Automatic Stereology of Biological Tissue Using 3-D VCS	stereology, VCS, automatic, cell counting	Chester	MD
SurModics, Inc.	IMPROVED BIOCOMPATIBILITY OF CONTACT LENSES	Surface modification, Immobilization chemistry, Medical device coatings, Hemocompatibility, Cell encapsulation, Drug-eluting coatings, DNA immobilization, Photoactivation	Eden Prairie	MN
Talisman Limited	Paperless Quality Donor System with Decision Making	CASI, AVT-CASI , automated interviewing, blood donors, error reduction , honesty, staff satisfaction, donor satisfaction	Vienna	VA
Targeting Systems	NOVEL APPROACH FOR TARGETED GENE DELIVERY TO THE LIVER	High throughput screening, Transfection, Protein delivery, siRNA delivery/screening, Luciferase assays/vectors, Lentiviral vectors, Stem cell tracking, Stem cell transfections	Santee	CA
Telesage, Inc.	NEW AUTOMATED TELEPHONE TECHNOLOGY FOR MENTAL HEALTH	Patient-Reported Outcomes, IVR, CAT, Mental Health, Substance Abuse, Interactive Voice, Computerized Adaptive, IRT	Chapel Hill	NC
The Degge Group, Ltd.	LEVELS OF LEARNING ABOUT CANCER BY PEDIATRIC PATIENTS	leukemia, child, cancer, education, interactive, multimedia, CD-ROM, pediatric	Arlington	VA
Three Rivers Holdings, LLC	The SmartWheel: Development of Wheelchair Pushrim Force and Measurement Device	wheelchairs, wheelchair propulsion, wheelchair biomechanics, measurement, wheelchair positioning, wheelchair selection, wheelchair seating, insurance justification	Mesa	AZ
TissueTech, Inc.	Development of Sutureless Amniotic Membrane Graft (AmnioLens)	amniotic membrane, ocular surface, wound repair, wound healing, eye surgery, corneal defects, chemical burns, Stevens-Johnson Syndrome	Miami	FL
Transonic Systems, Inc.	Flow Measurement at Dialysis Access Salvage	Blood, Dilution, Hemodialysis, Angioplasty, Access Flow, Stenosis, PTFE Graft, Fistulae	Ithaca	NY
Transonic Systems, Inc.	A Flowmeter with Telemetry for Chronic Animal Studies	Wireless, Transit-Time, Flow, Ultrasound, Bluetooth, Telemetry, Flowmeter, Manufacturing	Ithaca	NY
Turbo Wheelchair Co., Inc.	Lightweight Durable Wheelchair from Engineering Resin	wheelchair, MRI wheelchair, mobility for seniors, plastic wheelchair	Beaufort	SC
Vida Health Communications, Inc.	Fetal Alcohol Syndrome - Prevention, Diagnosis, Treatment: A Clinical Guide for Obstetric and Pediatric Providers	FAS, Prenatal Alcohol Exposure, Obstetrician education, Pediatrician education, Birth Defects, Alcohol-Related defects, FAS Diagnosis, FAS Treatment	Cambridge	MA
ViewPlus Inc.	The Accessible Graphics Reader for Blind People	tactile graphics, braille, blindness, dyslexia, accessibility, ink and braille, audio/touch, graphical information	Corvallis	OR
Vivalog Technologies	An Application Server for Biomedical Content Management	content management, radiology teaching files, medical image repository, PACS, enterprise software	Seattle	WA
Xilas Medical, Inc.	Medical devices that prevent the occurrence of foot ulcers and amputations in people with diabetes	diabetes, diabetic foot ulcer, amputations, friction, dermal thermometer, early warning tool, GlideSoft, TempTouch	San Antonio	TX
Xoran Technologies Inc.	MiniCAT™	MiniCAT, i-CAT, 3D x-ray, Computed Tomography (CT), CT scanner, Temporal Bone CT, Skull-Base CT	Ann Arbor	MI

SBIR/STTR Success Stories entered up through 2002 are shown below (most files in PDF format):

• Behavior Therapy Associates
• Cleveland Medical Devices, Inc.
• Decision Systems, Inc.
• Echelon Research Laboratories, Inc.
• Evening Star Productions.
• I.S. Grupe, Inc.
• Lexical Technology
• New England Research Institutes
• PanVera Corporation
• Transonic Systems Inc. PDF or MS Word

Congratulations to the following NIH SBIR awardees who were recipients of the 1999 Tibbetts Awards! These prestigious, national awards, named for Roland Tibbetts, a former SBIR Program Manager who is acknowledged as "founding father of the SBIR Program," are made annually to those small firms, projects, organizations and individuals judged to exemplify the very best in SBIR achievement. The Tibbetts Awards are an initiative of the Office of Advocacy in the US Small Business Administration (SBA) now managed through the Office of Technology. A full list of winners is available electronically at http://www.sba.gov/sbir/tibbetts/toc.html. (Note: All files below are in PDF format.)

• Beneficial Designs, Inc.
• Decision Systems, Inc.
• Thermogen, Inc.
• Bioanalytical Systems, Inc.
• Science and Engineering Services, Inc.
• Microwave Medical Systems, Inc.
• AVANT Immunotherapeutics, Inc.
• Evening Star Productions
• YES Technologies (Yellowstone Environmental Science, Inc.)

Note: For help accessing PDF, RTF, MS Word, Excel, PowerPoint, RealPlayer, Video or Flash files, see Help Downloading Files.