| | Commentaries Decisions by regulatory agencies: are they evidence-based? Curt D Furberg PMCID: PMC1852571 OMERACT: An international initiative to improve outcome measurement in rheumatology Peter Tugwell, Maarten Boers, Peter Brooks, Lee Simon, Vibeke Strand, and Leanne Idzerda PMCID: PMC2169260 Standardising outcomes for clinical trials and systematic reviews Mike Clarke PMCID: PMC2169261 Letter to the Editor Handheld computers for data entry: high tech has its problems too Tania M Shelby-James, Amy P Abernethy, Andrew McAlindon, and David C Currow PMCID: PMC1804282 Methodology Application and investigation of a bound for outcome reporting bias Paula R Williamson and Carrol Gamble PMCID: PMC1821040 "Me's me and you's you": Exploring patients' perspectives of single patient (n-of-1) trials in the UK Sara T Brookes, Lucy Biddle, Charlotte Paterson, Gillian Woolhead, and Paul Dieppe PMCID: PMC1831792 Method for evaluating prediction models that apply the results of randomized trials to individual patients Andrew J Vickers, Michael W Kattan, and Daniel Sargent PMCID: PMC1914366 Practical methods for incorporating summary time-to-event data into meta-analysis Jayne F Tierney, Lesley A Stewart, Davina Ghersi, Sarah Burdett, and Matthew R Sydes PMCID: PMC1920534 Responder analyses and the assessment of a clinically relevant treatment effect Steven M Snapinn and Qi Jiang PMCID: PMC2164942 Recruitment of young women to a trial of chlamydia screening – as easy as it sounds? Helen Atherton, Debbie Banks, Ruth Harbit, Linzie Long, Fiona Chadd, Phillip Hay, Sally Kerry, Ian Simms, and Pippa Oakeshott PMCID: PMC2212649 Research Feasibility study to inform the design of a UK multi-centre randomised controlled trial of prophylactic antibiotics for the prevention of recurrent cellulitis of the leg Kim S Thomas, Neil H Cox, Boki SP Savelyich, Debbie Shipley, Sarah Meredith, Andrew Nunn, Nick Reynolds, Hywel C Williams, and on behalf of the UK Dermatology Clinical Trials Network (UK DCTN) PMCID: PMC1797057 Does it matter if clinicians recruiting for a trial don't understand what the trial is really about? Qualitative study of surgeons' experiences of participation in a pragmatic multi-centre RCT Sue Ziebland, Katie Featherstone, Claire Snowdon, Karen Barker, Helen Frost, and Jeremy Fairbank PMCID: PMC1794540 Continuity and change?: Exploring reactions to a guided self-management intervention in a randomised controlled trial for IBS with reference to prior experience of managing a long term condition Anne Rogers, Victoria Lee, and Anne Kennedy PMCID: PMC1819391 Likely country of origin in publications on randomised controlled trials and controlled clinical trials during the last 60 years Christian Gluud and Dimitrinka Nikolova PMCID: PMC1808475 Phase II study of two dose schedules of C.E.R.A. (Continuous Erythropoietin Receptor Activator) in anemic patients with advanced non-small cell lung cancer (NSCLC) receiving chemotherapy Vera Hirsh, John Glaspy, Paul Mainwaring, Christian Manegold, Rodryg Ramlau, and Joseph E Eid PMCID: PMC1831793 Evaluation of two formulations of adjuvanted RTS, S malaria vaccine in children aged 3 to 5 years living in a malaria-endemic region of Mozambique: a Phase I/IIb randomized double-blind bridging trial Eusebio V Macete, Jahit Sacarlal, John J Aponte, Amanda Leach, Margarita M Navia, Jessica Milman, Caterina Guinovart, Inacio Mandomando, Yolanda López-Púa, Marc Lievens, Alex Owusu-Ofori, Marie-Claude Dubois, Conor P Cahill, Marguerite Koutsoukos, Marla Sillman, Ricardo Thompson, Filip Dubovsky, W Ripley Ballou, Joe Cohen, and Pedro L Alonso PMCID: PMC1847838 Importance of competing risks in the analysis of anti-epileptic drug failure Paula R Williamson, Catrin Tudur Smith, Josemir W Sander, and Anthony G Marson PMCID: PMC1853111 Do trialists endorse clinical trial registration? Survey of a Pubmed sample Ludovic Reveiz, Karmela Krleža-Jerić, An-Wen Chan, and Sylvia De Aguiar PMCID: PMC2147029 Multiple treatment comparisons in epilepsy monotherapy trials Catrin Tudur Smith, Anthony G Marson, David W Chadwick, and Paula R Williamson1 PMCID: PMC2194733 Figures in clinical trial reports: current practice & scope for improvement Stuart J Pocock, Thomas G Travison, and Lisa M Wruck PMCID: PMC2222221 Marketing and clinical trials: a case study David Francis, Ian Roberts, Diana R Elbourne, Haleema Shakur, Rosemary C Knight, Jo Garcia, Claire Snowdon, Vikki A Entwistle, Alison M McDonald, Adrian M Grant, and Marion K Campbell PMCID: PMC2212650 Review Outcome measurement in clinical trials for Ulcerative Colitis: towards standardisation Rachel M Cooney, Bryan F Warren, Douglas G Altman, Maria T Abreu, and Simon PL Travis PMCID: PMC1919394 Study Protocol The Leeds Evaluation of Efficacy of Detoxification Study (LEEDS) prisons project pilot study: protocol for a randomised controlled trial comparing dihydrocodeine and buprenorphine for opiate detoxification Laura Sheard, Clive E Adams, Nat MJ Wright, Hany El-Sayeh, Richard Dalton, and Charlotte NE Tompkins PMCID: PMC1780064 Multicenter randomized trial of cell therapy in cardiopathies – MiHeart Study Bernardo R Tura, Helena F Martino, Luis H Gowdak, Ricardo Ribeiro dos Santos, Hans F Dohmann, José E Krieger, Gilson Feitosa, Fábio Vilas-Boas, Sérgio A Oliveira, Suzana A Silva, Augusto Z Bozza, Radovan Borojevic, and Antonio C Campos de Carvalho PMCID: PMC1783861 Silent cerebral infarct after cardiac catheterization as detected by diffusion weighted Magnetic Resonance Imaging: a randomized comparison of radial and femoral arterial approaches Michèle Hamon, Francesco Burzotta, Catherine Oppenheim, Rémy Morello, Fausto Viader, Martial Hamon, and the SCIPION Investigators PMCID: PMC1896179 Telecare motivational interviewing for diabetes patient education and support: a randomised controlled trial based in primary care comparing nurse and peer supporter delivery Jeremy Dale, Isabela Caramlau, Andrea Docherty, Jackie Sturt, and Hilary Hearnshaw PMCID: PMC1934921 Is looped nasogastric tube feeding more effective than conventional nasogastric tube feeding for dysphagia in acute stroke? Jessica R Beavan, Simon Conroy, Jo Leonardi-Bee, Tim Bowling, Catherine Gaynor, John Gladman, Dawn Good, Peter Gorman, Rowan Harwood, Jan Riley, Tracey Sach, and Wayne Sunman PMCID: PMC1976319 PROUD: Effects of preoperative long-term immunonutrition in patients listed for liver transplantation Arash Nickkholgh, Heinz Schneider, Jens Encke, Markus W Büchler, Jan Schmidt, and Peter Schemmer PMCID: PMC2018725 Aspirin and Simvastatin Combination for Cardiovascular Events Prevention Trial in Diabetes (ACCEPT-D): design of a randomized study of the efficacy of low-dose aspirin in the prevention of cardiovascular events in subjects with diabetes mellitus treated with statins Giorgia De Berardis, Michele Sacco, Virgilio Evangelista, Alessandro Filippi, Carlo B Giorda, Gianni Tognoni, Umberto Valentini, Antonio Nicolucci, and ACCEPT-D Study Group PMCID: PMC2014771 Comparison of total parathyroidectomy without autotransplantation and without thymectomy versus total parathyroidectomy with autotransplantation and with thymectomy for secondary hyperparathyroidism: TOPAR PILOT-Trial Katja Schlosser, Johannes A Veit, Stefan Witte, Emilio Domínguez Fernández, Norbert Victor, Hans-Peter Knaebel, Christoph M Seiler, and Matthias Rothmund PMCID: PMC2075519 Structuring communication relationships for interprofessional teamwork (SCRIPT): a cluster randomized controlled trial Merrick Zwarenstein, Scott Reeves, Ann Russell, Chris Kenaszchuk, Lesley Gotlib Conn, Karen-Lee Miller, Lorelei Lingard, and Kevin E Thorpe PMCID: PMC2045094 Early loading of plalatal implants (ortho-type II) a prospective multicenter randomized controlled clinical trial Britta A Jung, Heinrich Wehrbein, Werner Hopfenmüller, Winfried Harzer, Tomasz Gedrange, Peter Diedrich, and Martin Kunkel PMCID: PMC2039736 Randomised trial of glutamine and selenium supplemented parenteral nutrition for critically ill patients. Protocol Version 9, 19 February 2007 known as SIGNET (Scottish Intensive care Glutamine or seleNium Evaluative Trial) Peter JD Andrews, Alison Avenell, David W Noble, Marion K Campbell, Claire G Battison, Bernard L Croal, William G Simpson, John Norrie, Luke D Vale, Jonathon Cook, Robyn de Verteuil, Anne C Milne, and The Trials Management Group PMCID: PMC2082027 Double blind, randomized, placebo controlled clinical trial for the treatment of diabetic foot ulcers, using a nitric oxide releasing patch: PATHON Sandra Y Silva, Ligia C Rueda, Gustavo A Márquez, Marcos López, Daniel J Smith, Carlos A Calderón, Juan C Castillo, Jaime Matute, Christian F Rueda-Clausen, Arturo Orduz, Federico A Silva, Piyaporn Kampeerapappun, Mahesh Bhide, and Patricio López-Jaramillo PMCID: PMC2092425 Safety and efficacy of botox injection in alleviating post-operative pain and improving quality of life in lower extremity limb lengthening and deformity correction Reggie C Hamdy, Kathleen Montpetit, Joanne Ruck-Gibis, Kelly Thorstad, Ellen Raney, Michael Aiona, Robert Platt, Allen Finley, William Mackenzie, James McCarthy, and Unni Narayanan PMCID: PMC2151066 A cluster randomized trial evaluating electronic prescribing in an ambulatory care setting Merrick F Zwarenstein, Katie N Dainty, Sherman Quan, Alex Kiss, and Neill KJ Adhikari PMCID: PMC2092426 Acute cholecystitis – early laparoskopic surgery versus antibiotic therapy and delayed elective cholecystectomy: ACDC-study Kilian Weigand, Jörg Köninger, Jens Encke, Markus W Büchler, Wolfgang Stremmel, and Carsten N Gutt PMCID: PMC2098782 Design of a multicentre randomized trial to evaluate CT colonography versus colonoscopy or barium enema for diagnosis of colonic cancer in older symptomatic patients: The SIGGAR study Steve Halligan, Richard J Lilford, Jane Wardle, Dion Morton, Pauline Rogers, Katherine Wooldrage, Rob Edwards, Reshma Kanani, Urvi Shah, and Wendy Atkin PMCID: PMC2174515 VERTOS II: Percutaneous vertebroplasty versus conservative therapy in patients with painful osteoporotic vertebral compression fractures; rationale, objectives and design of a multicenter randomized controlled trial CAH Klazen, HJJ Verhaar, LEH Lampmann, JR Juttmann, MC Blonk, FH Jansen, AV Tielbeek, MC Schoemaker, E Buskens, Y van der Graaf, X Janssens, H Fransen, KJ van Everdingen, AF Muller, WPThM Mali, and PNM Lohle PMCID: PMC2169262 Comparison of different dosing regimens (once weekly vs. twice weekly, and once weekly vs. once every two weeks) with epoetin delta in patients with chronic kidney disease: a randomized controlled trial Iain C Macdougall PMCID: PMC2216039 Breast MRI in nonpalpable breast lesions: a randomized trial with diagnostic and therapeutic outcome – MONET – study Nicky HGM Peters, Inne HM Borel Rinkes, Willem PTM Mali, Maurice AAJ van den Bosch, Remmert K Storm, Peter W Plaisier, Erwin de Boer, Adriaan J van Overbeeke, and Petra HM Peeters PMCID: PMC2222222 |
