| | Editorial One Year of PLoS Computational Biology Philip E Bourne PMCID: PMC1553486 Message from ISCB ISCB Honors Michael S. Waterman and Mathieu Blanchette Merry Maisel PMCID: PMC1526462 Review The Ion Channel Inverse Problem: Neuroinformatics Meets Biophysics Robert C Cannon and Giampaolo D'Alessandro PMCID: PMC1553477 Research Articles An Integrative Method for Accurate Comparative Genome Mapping Firas Swidan, Eduardo P. C Rocha, Michael Shmoish, and Ron Y Pinter PMCID: PMC1526463 Intrinsic Disorder Is a Common Feature of Hub Proteins from Four Eukaryotic Interactomes Chad Haynes, Christopher J Oldfield, Fei Ji, Niels Klitgord, Michael E Cusick, Predrag Radivojac, Vladimir N Uversky, Marc Vidal, and Lilia M Iakoucheva PMCID: PMC1526461 Matrix Formalism to Describe Functional States of Transcriptional Regulatory Systems Erwin P Gianchandani, Jason A Papin, Nathan D Price, Andrew R Joyce, and Bernhard O Palsson PMCID: PMC1534074 Insights into the Coupling of Duplication Events and Macroevolution from an Age Profile of Animal Transmembrane Gene Families Guohui Ding, Jiuhong Kang, Qi Liu, Tieliu Shi, Gang Pei, and Yixue Li PMCID: PMC1534073 Transient Resetting: A Novel Mechanism for Synchrony and Its Biological Examples Chunguang Li, Luonan Chen, and Kazuyuki Aihara PMCID: PMC1526460 Conservation of Expression and Sequence of Metabolic Genes Is Reflected by Activity Across Metabolic States Yonatan Bilu, Tomer Shlomi, Naama Barkai, and Eytan Ruppin PMCID: PMC1550272 Modeling Somatic Evolution in Tumorigenesis Sabrina L Spencer, Ryan A Gerety, Kenneth J Pienta, and Stephanie Forrest PMCID: PMC1550273 High Epitope Expression Levels Increase Competition between T Cells Almut Scherer, Marcel Salathé, and Sebastian Bonhoeffer PMCID: PMC1550274 Expansion of Protein Domain Repeats Åsa K Björklund, Diana Ekman, and Arne Elofsson PMCID: PMC1553488 Correction Correction: Systematic Analysis of Head-to-Head Gene Organization: Evolutionary Conservation and Potential Biological Relevance Yuan-Yuan Li, Hui Yu, Zong-Ming Guo, Ting-Qing Guo, Kang Tu, and Yi-Xue Li PMCID: PMC1553487 Corrects: Yuan-Yuan Li, et al. Systematic Analysis of Head-to-Head Gene Organization: Evolutionary Conservation and Potential Biological Relevance. PLoS Comput Biol. 2006 July; 2(7): e74. |
