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Volume 101(2);  January 13, 2004
Commentaries
Cyclooxygenase 2-derived prostaglandin E2 regulates the angiogenic switch
Dingzhi Wang and Raymond N. DuBois
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 415–416. Published online 2004 January 5. doi: 10.1073/pnas.0307640100.
PMCID: PMC327160
A myristoyl switch regulates membrane binding of HIV-1 Gag
Marilyn D. Resh
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 417–418. Published online 2004 January 5. doi: 10.1073/pnas.0308043101.
PMCID: PMC327161
Physical Sciences
Chemistry
H-bonded N-heterocyclic base-pair phototautomerizational potential barrier and mechanism: The 7-azaindole dimer
J. Catalán, P. Pérez, J. C. del Valle, J. L. G. de Paz, and M. Kasha
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 419–422. Published online 2003 December 30. doi: 10.1073/pnas.0306721101.
PMCID: PMC327162
Geophysics
Soot climate forcing via snow and ice albedos
James Hansen and Larissa Nazarenko
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 423–428. Published online 2003 December 29. doi: 10.1073/pnas.2237157100.
PMCID: PMC327163
Physics
Organic light-emitting diodes formed by soft contact lamination
Tae-Woo Lee, Jana Zaumseil, Zhenan Bao, Julia W. P. Hsu, and John A. Rogers
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 429–433. Published online 2004 January 2. doi: 10.1073/pnas.0304179101.
PMCID: PMC327164
Biological Sciences
Biochemistry
Identification of Lhp1p-associated RNAs by microarray analysis in Saccharomyces cerevisiae reveals association with coding and noncoding RNAs
Maki Inada and Christine Guthrie
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 434–439. Published online 2004 January 2. doi: 10.1073/pnas.0307425100.
PMCID: PMC327165
The second extracellular loop of the dopamine D2 receptor lines the binding-site crevice
Lei Shi and Jonathan A. Javitch
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 440–445. Published online 2004 January 2. doi: 10.1073/pnas.2237265100.
PMCID: PMC327166
A functional Ni-Ni-[4Fe-4S] cluster in the monomeric acetyl-CoA synthase from Carboxydothermus hydrogenoformans
Vitali Svetlitchnyi, Holger Dobbek, Wolfram Meyer-Klaucke, Thomas Meins, Bärbel Thiele, Piero Römer, Robert Huber, and Ortwin Meyer
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 446–451. Published online 2003 December 29. doi: 10.1073/pnas.0304262101.
PMCID: PMC327167
Bacillus subtilis RecU protein cleaves Holliday junctions and anneals single-stranded DNA
Silvia Ayora, Begoña Carrasco, Ernesto Doncel, Rudi Lurz, and Juan C. Alonso
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 452–457. Published online 2003 December 30. doi: 10.1073/pnas.2533829100.
PMCID: PMC327168
Myc-interacting protein 1 target gene profile: A link to microtubules, extracellular signal-regulated kinase, and cell growth
Joseph Ziegelbauer, Joyce Wei, and Robert Tjian
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 458–463. Published online 2004 January 2. doi: 10.1073/pnas.0307562100.
PMCID: PMC327169
Physical and functional interaction of androgen receptor with calmodulin in prostate cancer cells
Eugenia Cifuentes, Jennifer M. Mataraza, Barbara A. Yoshida, Mani Menon, David B. Sacks, Evelyn R. Barrack, and G. Prem-Veer Reddy
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 464–469. Published online 2003 December 26. doi: 10.1073/pnas.0307161101.
PMCID: PMC327170
From the Cover:
A proteomic approach for the analysis of instantly released wound and immune proteins in Drosophila melanogaster hemolymph
Evy Vierstraete, Peter Verleyen, Geert Baggerman, Wannes D'Hertog, Gert Van den Bergh, Lutgarde Arckens, Arnold De Loof, and Liliane Schoofs
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 470–475. Published online 2004 January 5. doi: 10.1073/pnas.0304567101.
PMCID: PMC327171
Context-dependent regulation of GATA-1 by friend of GATA-1
Danielle L. Letting, Ying-Yu Chen, Carrie Rakowski, Sarah Reedy, and Gerd A. Blobel
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 476–481. Published online 2003 December 26. doi: 10.1073/pnas.0306315101.
PMCID: PMC327172
Directed evolution of mammalian paraoxonases PON1 and PON3 for bacterial expression and catalytic specialization
Amir Aharoni, Leonid Gaidukov, Shai Yagur, Lilly Toker, Israel Silman, and Dan S. Tawfik
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 482–487. Published online 2003 December 26. doi: 10.1073/pnas.2536901100.
PMCID: PMC327173
From the Cover:
Analysis of C5a-mediated chemotaxis by lentiviral delivery of small interfering RNA
Jong-Ik Hwang, Iain D. C. Fraser, Sangdun Choi, Xiao-Feng Qin, and Melvin I. Simon
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 488–493. Published online 2003 December 29. doi: 10.1073/pnas.0307549100.
PMCID: PMC327174
Availability of specific reductases controls the temporal activity of the cytochrome P450 complement of Streptomyces coelicolor A3(2)
Li Lei, Michael R. Waterman, Armand J. Fulco, Steven L. Kelly, and David C. Lamb
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 494–499. Published online 2004 January 2. doi: 10.1073/pnas.2435922100.
PMCID: PMC327175
Demonstration of mammalian protein O-mannosyltransferase activity: Coexpression of POMT1 and POMT2 required for enzymatic activity
Hiroshi Manya, Atsuro Chiba, Aruto Yoshida, Xiaohui Wang, Yasunori Chiba, Yoshifumi Jigami, Richard U. Margolis, and Tamao Endo
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 500–505. Published online 2003 December 29. doi: 10.1073/pnas.0307228101.
PMCID: PMC327176
Biophysics
The origin of vibrational mode couplings in various secondary structural motifs of polypeptides
Andrew Moran and Shaul Mukamel
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 506–510. Published online 2004 January 2. doi: 10.1073/pnas.2533089100.
PMCID: PMC327177
Protein topology determines binding mechanism
Yaakov Levy, Peter G. Wolynes, and José N. Onuchic
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 511–516. Published online 2003 December 23. doi: 10.1073/pnas.2534828100.
PMCID: PMC327178
From the Cover:
Entropic switch regulates myristate exposure in the HIV-1 matrix protein
Chun Tang, Erin Loeliger, Paz Luncsford, Isaac Kinde, Dorothy Beckett, and Michael F. Summers
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 517–522. Published online 2003 December 29. doi: 10.1073/pnas.0305665101.
PMCID: PMC327179
Monitoring protein stability and aggregation in vivo by real-time fluorescent labeling
Zoya Ignatova and Lila M. Gierasch
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 523–528. Published online 2003 December 30. doi: 10.1073/pnas.0304533101.
PMCID: PMC327180
The catalytic cycle of cytochrome c oxidase is not the sum of its two halves
Dmitry Bloch, Ilya Belevich, Audrius Jasaitis, Camilla Ribacka, Anne Puustinen, Michael I. Verkhovsky, and Mårten Wikström
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 529–533. Published online 2003 December 29. doi: 10.1073/pnas.0306036101.
PMCID: PMC327181
Single-molecule studies highlight conformational heterogeneity in the early folding steps of a large ribozyme
Zheng Xie, Narayanan Srividya, Tobin R. Sosnick, Tao Pan, and Norbert F. Scherer
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 534–539. Published online 2004 January 2. doi: 10.1073/pnas.2636333100.
PMCID: PMC327182
Cell Biology
Transcriptional signature of histone deacetylase inhibition in multiple myeloma: Biological and clinical implications
Constantine S. Mitsiades, Nicholas S. Mitsiades, Ciaran J. McMullan, Vassiliki Poulaki, Reshma Shringarpure, Teru Hideshima, Masaharu Akiyama, Dharminder Chauhan, Nikhil Munshi, Xuesong Gu, Charles Bailey, Marie Joseph, Towia A. Libermann, Victoria M. Richon, Paul A. Marks, and Kenneth C. Anderson
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 540–545. Published online 2003 December 26. doi: 10.1073/pnas.2536759100.
PMCID: PMC327183
Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses
Sang Yoon Lee, Markus R. Wenk, Yong Kim, Angus C. Nairn, and Pietro De Camilli
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 546–551. Published online 2004 January 2. doi: 10.1073/pnas.0307813100.
PMCID: PMC327184
Conditional targeting of E-cadherin in skin: Insights into hyperproliferative and degenerative responses
Christopher L. Tinkle, Terry Lechler, H. Amalia Pasolli, and Elaine Fuchs
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 552–557. Published online 2004 January 2. doi: 10.1073/pnas.0307437100.
PMCID: PMC327185
Ecology
From the Cover:
Hatching failure increases with severity of population bottlenecks in birds
James V. Briskie and Myles Mackintosh
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 558–561. Published online 2003 December 29. doi: 10.1073/pnas.0305103101.
PMCID: PMC327186
Response of C3 and C4 plants to middle-Holocene climatic variation near the prairie–forest ecotone of Minnesota
David M. Nelson, Feng Sheng Hu, Jian Tian, Ivanka Stefanova, and Thomas A. Brown
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 562–567. Published online 2003 December 30. doi: 10.1073/pnas.0307450100.
PMCID: PMC327187
Evolution
Phylogenetic evidence for the early evolution of microcystin synthesis
Anne Rantala, David P. Fewer, Michael Hisbergues, Leo Rouhiainen, Jaana Vaitomaa, Thomas Börner, and Kaarina Sivonen
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 568–573. Published online 2003 December 30. doi: 10.1073/pnas.0304489101.
PMCID: PMC327188
Genetics
Loss of CDX1 expression in colorectal carcinoma: Promoter methylation, mutation, and loss of heterozygosity analyses of 37 cell lines
N. A. C. S. Wong, M. P. Britton, G. S. Choi, T. K. Stanton, D. C. Bicknell, J. L. Wilding, and W. F. Bodmer
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 574–579. Published online 2004 January 2. doi: 10.1073/pnas.0307190101.
PMCID: PMC327189
Design of genetic networks with specified functions by evolution in silico
Paul François and Vincent Hakim
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 580–585. Published online 2004 January 2. doi: 10.1073/pnas.0304532101.
PMCID: PMC327190
Immunology
IL-13 receptor α 2 down-modulates granulomatous inflammation and prolongs host survival in schistosomiasis
Margaret M. Mentink-Kane, Allen W. Cheever, Robert W. Thompson, Danielle M. Hari, Narcis B. Kabatereine, Birgitte J. Vennervald, John H. Ouma, Joseph K. Mwatha, Frances M. Jones, Debra D. Donaldson, Michael J. Grusby, David W. Dunne, and Thomas A. Wynn
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 586–590. Published online 2003 December 29. doi: 10.1073/pnas.0305064101.
PMCID: PMC327191
Medical Sciences
From the Cover:
Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression
Sung-Hee Chang, Catherine H. Liu, Rebecca Conway, David K. Han, Kasem Nithipatikom, Ovidiu C. Trifan, Timothy F. Lane, and Timothy Hla
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 591–596. Published online 2003 December 19. doi: 10.1073/pnas.2535911100.
PMCID: PMC327192
Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder
Benjamin S. Braun, David A. Tuveson, Namie Kong, Doan T. Le, Scott C. Kogan, Jacob Rozmus, Michelle M. Le Beau, Tyler E. Jacks, and Kevin M. Shannon
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 597–602. Published online 2003 December 29. doi: 10.1073/pnas.0307203101.
PMCID: PMC327193
Electrocardiographic and other cardiac anomalies in β-glucuronidase-null mice corrected by nonablative neonatal marrow transplantation
A. J. T. Schuldt, T. J. Hampton, V. Chu, C. A. Vogler, N. Galvin, M. D. Lessard, and J. E. Barker
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 603–608. Published online 2004 January 2. doi: 10.1073/pnas.0305284101.
PMCID: PMC327194
Defective lysosomal targeting of activated fibroblast growth factor receptor 3 in achondroplasia
Jay Y. Cho, Changsheng Guo, Monica Torello, Gregory P. Lunstrum, Tomoko Iwata, Chuxia Deng, and William A. Horton
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 609–614. Published online 2003 December 29. doi: 10.1073/pnas.2237184100.
PMCID: PMC327195
In silico dissection of cell-type-associated patterns of gene expression in prostate cancer
Robert O. Stuart, William Wachsman, Charles C. Berry, Jessica Wang-Rodriguez, Linda Wasserman, Igor Klacansky, Dan Masys, Karen Arden, Steven Goodison, Michael McClelland, Yipeng Wang, Anne Sawyers, Iveta Kalcheva, David Tarin, and Dan Mercola
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 615–620. doi: 10.1073/pnas.2536479100.
PMCID: PMC327196
Binding of mouse VL30 retrotransposon RNA to PSF protein induces genes repressed by PSF: Effects on steroidogenesis and oncogenesis
Xu Song, Aiwei Sui, and Alan Garen
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 621–626. Published online 2004 January 2. doi: 10.1073/pnas.0307794100.
PMCID: PMC327197
Microbiology
The chitinolytic cascade in Vibrios is regulated by chitin oligosaccharides and a two-component chitin catabolic sensor/kinase
Xibing Li and Saul Roseman
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 627–631. Published online 2003 December 29. doi: 10.1073/pnas.0307645100.
PMCID: PMC327198
Nonrandom HIV-1 infection and double infection via direct and cell-mediated pathways
Que Dang, Jianbo Chen, Derya Unutmaz, John M. Coffin, Vinay K. Pathak, Douglas Powell, Vineet N. KewalRamani, Frank Maldarelli, and Wei-Shau Hu
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 632–637. Published online 2004 January 5. doi: 10.1073/pnas.0307636100.
PMCID: PMC327199
Residual integrated viral DNA after hepadnavirus clearance by nucleoside analog therapy
Jesse Summers and William S. Mason
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 638–640. Published online 2003 December 29. doi: 10.1073/pnas.0307422100.
PMCID: PMC327200
Transcriptome-based determination of multiple transcription regulator activities in Escherichia coli by using network component analysis
Katy C. Kao, Young-Lyeol Yang, Riccardo Boscolo, Chiara Sabatti, Vwani Roychowdhury, and James C. Liao
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 641–646. Published online 2003 December 23. doi: 10.1073/pnas.0305287101.
PMCID: PMC327201
Neuroscience
Identification of calcium- and nitric oxide-regulated genes by differential analysis of library expression (DAzLE)
Huiwu Li, Xiujing Gu, Valina L. Dawson, and Ted M. Dawson
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 647–652. Published online 2003 December 30. doi: 10.1073/pnas.0305145101.
PMCID: PMC327202
NADH augments blood flow in physiologically activated retina and visual cortex
Yasuo Ido, Katherine Chang, and Joseph R. Williamson
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 653–658. Published online 2004 January 2. doi: 10.1073/pnas.0307458100.
PMCID: PMC327203
Increased lactate/pyruvate ratio augments blood flow in physiologically activated human brain
Mark A. Mintun, Andrei G. Vlassenko, Melissa M. Rundle, and Marcus E. Raichle
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 659–664. Published online 2004 January 2. doi: 10.1073/pnas.0307457100.
PMCID: PMC327204
JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease
Stéphane Hunot, Miquel Vila, Peter Teismann, Roger J. Davis, Etienne C. Hirsch, Serge Przedborski, Pasko Rakic, and Richard A. Flavell
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 665–670. Published online 2004 January 2. doi: 10.1073/pnas.0307453101.
PMCID: PMC327205
Association of β-catenin with the α-subunit of neuronal large-conductance Ca2+-activated K+ channels
F. Lesage, H. Hibino, and A. J. Hudspeth
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 671–675. Published online 2003 December 30. doi: 10.1073/pnas.0307681100.
PMCID: PMC327206
Protein phosphatase 2A inhibition induces cerebellar long-term depression and declustering of synaptic AMPA receptor
T. Launey, S. Endo, R. Sakai, J. Harano, and M. Ito
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 676–681. Published online 2003 December 29. doi: 10.1073/pnas.0302914101.
PMCID: PMC327207
Functional expression in frog oocytes of human ρ1 receptors produced in Saccharomyces cerevisiae
Alejandro Martínez-Martínez, Jorge Mauricio Reyes-Ruiz, Ataúlfo Martínez-Torres, and Ricardo Miledi
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 682–686. Published online 2004 January 2. doi: 10.1073/pnas.0307564100.
PMCID: PMC327208
Plant Biology
RF2b, a rice bZIP transcription activator, interacts with RF2a and is involved in symptom development of rice tungro disease
Shunhong Dai, Zhihong Zhang, Shouyi Chen, and Roger N. Beachy
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 687–692. Published online 2004 January 2. doi: 10.1073/pnas.0307687100.
PMCID: PMC327209
Correction
Proc Natl Acad Sci U S A. 2004 January 13; 101(2): 693. Published online 2003 December 23. doi: 10.1073/pnas.2637170100.
PMCID: PMC327210
Corrects: Kent E. Vrana, et al. Colloquium Paper: Regenerative Medicine: Nonhuman primate parthenogenetic stem cells. Proc Natl Acad Sci U S A. 2003 September 30; 100(Suppl 1): 11911–11916.
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