| | This journal provides immediate access to some articles. Commentaries Secondary loss of chloroplasts in trypanosomes William Martin and Piet Borst PMCID: PMC298673 Flow, NO, and atherogenesis John P. Cooke PMCID: PMC298674 Hysteresis meets the cell cycle Mark J. Solomon PMCID: PMC298675 The dichotomy of complex I: A sodium ion pump or a proton pump Judy Hirst PMCID: PMC298676 Perspective Multiple mutations and cancer Lawrence A. Loeb, Keith R. Loeb, and Jon P. Anderson PMCID: PMC298677 Physical Sciences Applied Mathematics Coarse-grained stochastic processes for microscopic lattice systems Markos A. Katsoulakis, Andrew J. Majda, and Dionisios G. Vlachos PMCID: PMC298678 Least effort and the origins of scaling in human language Ramon Ferrer i Cancho and Ricard V. Solé PMCID: PMC298679 Chemistry Diffusion-limited kinetics of the solution–solid phase transition of molecular substances Dimiter N. Petsev, Kai Chen, Olga Gliko, and Peter G. Vekilov PMCID: PMC298680 Reactivity-based one-pot total synthesis of fucose GM1 oligosaccharide: A sialylated antigenic epitope of small-cell lung cancer Tony Kwok-Kong Mong, Hing-Ken Lee, Sergio G. Durón, and Chi-Huey Wong PMCID: PMC298681 Evaporation and instabilities of microscopic capillary bridges Nobuo Maeda, Jacob N. Israelachvili, and Mika M. Kohonen PMCID: PMC298682 The missing link between thermodynamics and structure in F1-ATPase W. Yang, Y. Q. Gao, Q. Cui, J. Ma, and M. Karplus PMCID: PMC298694 Observation of liquid–liquid phase separation for eye lens γS-crystallin Onofrio Annunziata, Olutayo Ogun, and George B. Benedek PMCID: PMC298710 Biological Sciences Agricultural Sciences Sex pheromone biosynthetic pathway for disparlure in the gypsy moth, Lymantria dispar Russell A. Jurenka, Mitko Subchev, José-Luis Abad, Man-Yeon Choi, and Gemma Fabriàs PMCID: PMC298683 Applied Biological Sciences Microbe forensics: Oxygen and hydrogen stable isotope ratios in Bacillus subtilis cells and spores Helen W. Kreuzer-Martin, Michael J. Lott, Janet Dorigan, and James R. Ehleringer PMCID: PMC298684 Direct detection of antibody–antigen binding using an on-chip artificial pore Omar A. Saleh and Lydia L. Sohn PMCID: PMC298685 INAUGURAL ARTICLE by a Recently Elected Academy Member: Engineering the metabolism of Escherichia coli W3110 for the conversion of sugar to redox-neutral and oxidized products: Homoacetate production T. B. Causey, S. Zhou, K. T. Shanmugam, and L. O. Ingram PMCID: PMC298686 Biochemistry Diffusion-limited kinetics of the solution–solid phase transition of molecular substances Dimiter N. Petsev, Kai Chen, Olga Gliko, and Peter G. Vekilov PMCID: PMC298680 Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance Isabelle Dussault, Hye-Dong Yoo, Min Lin, Eric Wang, Ming Fan, Ashok K. Batta, Gerald Salen, Sandra K. Erickson, and Barry M. Forman PMCID: PMC298687 From the Cover:
Sodium ion cycling mediates energy coupling between complex I and ATP synthase Anja C. Gemperli, Peter Dimroth, and Julia Steuber PMCID: PMC298688 Crystal structure of the MurG:UDP-GlcNAc complex reveals common structural principles of a superfamily of glycosyltransferases Yanan Hu, Lan Chen, Sha Ha, Ben Gross, Brian Falcone, Deborah Walker, Maryam Mokhtarzadeh, and Suzanne Walker PMCID: PMC298689 CCAAT/enhancer-binding protein β is required for mitotic clonal expansion during adipogenesis Qi-Qun Tang, Tamara C. Otto, and M. Daniel Lane PMCID: PMC298690 Structural evidence for substrate strain in antibody catalysis Jun Yin, Scott E. Andryski, Albert E. Beuscher, IV, Raymond C. Stevens, and Peter G. Schultz PMCID: PMC298691 Evolution of feedback-inhibited β/α barrel isoenzymes by gene duplication and a single mutation Markus Hartmann, Thomas R. Schneider, Andrea Pfeil, Gabriele Heinrich, William N. Lipscomb, and Gerhard H. Braus PMCID: PMC298692 Structure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexes Cindy R. Sinars, Joyce Cheung-Flynn, Ronald A. Rimerman, Jonathan G. Scammell, David F. Smith, and Jon Clardy PMCID: PMC298693 The missing link between thermodynamics and structure in F1-ATPase W. Yang, Y. Q. Gao, Q. Cui, J. Ma, and M. Karplus PMCID: PMC298694 Quantitation of changes in protein phosphorylation: A simple method based on stable isotope labeling and mass spectrometry Débora Bonenfant, Tobias Schmelzle, Estela Jacinto, José L. Crespo, Thierry Mini, Michael N. Hall, and Paul Jenoe PMCID: PMC298695 A photochemical approach to the lipid accessibility of engineered cysteinyl residues Jing Li, Lei Shi, and Arthur Karlin PMCID: PMC298696 Unique mitochondrial genome architecture in unicellular relatives of animals Gertraud Burger, Lise Forget, Yun Zhu, Michael W. Gray, and B. Franz Lang PMCID: PMC298697 Origin-specific unwinding of herpes simplex virus 1 DNA by the viral UL9 and ICP8 proteins: Visualization of a specific preunwinding complex Alexander M. Makhov, Sam S.-K. Lee, I. Robert Lehman, and Jack D. Griffith PMCID: PMC298698 Biochemical characterization of the Yersinia YopT protease: Cleavage site and recognition elements in Rho GTPases Feng Shao, Panayiotis O. Vacratsis, Zhaoqin Bao, Katherine E. Bowers, Carol A. Fierke, and Jack E. Dixon PMCID: PMC298699 Mechanistic studies of β-arylsulfotransferase IV Eli Chapman, Marian C. Bryan, and Chi-Huey Wong PMCID: PMC298700 Oncogenic targeting of an activated tyrosine kinase to the Golgi apparatus in a glioblastoma Alan Charest, Vicky Kheifets, Julie Park, Keara Lane, Kevin McMahon, Cathy L. Nutt, and David Housman PMCID: PMC298701 One scorpion, two venoms: Prevenom of Parabuthus transvaalicus acts as an alternative type of venom with distinct mechanism of action Bora Inceoglu, Jozsef Lango, Jie Jing, Lili Chen, Fuat Doymaz, Isaac N. Pessah, and Bruce D. Hammock PMCID: PMC298702 The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): Liver regeneration and neuronal differentiation Nabil G. Seidah, Suzanne Benjannet, Louise Wickham, Jadwiga Marcinkiewicz, Stéphanie Bélanger Jasmin, Stefano Stifani, Ajoy Basak, Annik Prat, and Michel Chrétien PMCID: PMC298703 A single-stranded promoter for RNA polymerase III Oliver Schröder, E. Peter Geiduschek, and George A. Kassavetis PMCID: PMC298704 β-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates β-adrenoceptor switching from Gs to Gi George S. Baillie, Arvind Sood, Ian McPhee, Irene Gall, Stephen J. Perry, Robert J. Lefkowitz, and Miles D. Houslay PMCID: PMC298705 Biophysics A quantitative structure–function relationship for the Photosystem II reaction center: Supermolecular behavior in natural photosynthesis Laura M. C. Barter, James R. Durrant, and David R. Klug PMCID: PMC298706 Determination of the energetics governing the regulatory step in growth hormone-induced receptor homodimerization Bryan Bernat, Gabor Pal, Miao Sun, and Anthony A. Kossiakoff PMCID: PMC298707 Hair-bundle movements elicited by transepithelial electrical stimulation of hair cells in the sacculus of the bullfrog D. Bozovic and A. J. Hudspeth PMCID: PMC298708 Conformational dynamics of the Na+/K+-ATPase probed by voltage clamp fluorometry Sven Geibel, Jack H. Kaplan, Ernst Bamberg, and Thomas Friedrich PMCID: PMC298709 Observation of liquid–liquid phase separation for eye lens γS-crystallin Onofrio Annunziata, Olutayo Ogun, and George B. Benedek PMCID: PMC298710 Cell Biology From the Cover:
Hysteresis drives cell-cycle transitions in Xenopus laevis egg extracts Wei Sha, Jonathan Moore, Katherine Chen, Antonio D. Lassaletta, Chung-Seon Yi, John J. Tyson, and Jill C. Sible PMCID: PMC298711 Depletion of a single nucleoporin, Nup107, prevents the assembly of a subset of nucleoporins into the nuclear pore complex Thomas Boehmer, Jost Enninga, Samuel Dales, Günter Blobel, and Hualin Zhong PMCID: PMC298712 Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia Katrina M. Comerford, Martin O. Leonard, Jorn Karhausen, Robyn Carey, Sean P. Colgan, and Cormac T. Taylor PMCID: PMC298713 The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12 Mark A. Hall, David J. Curtis, Donald Metcalf, Andrew G. Elefanty, K. Sourris, Lorraine Robb, Joachim R. Göthert, Stephen M. Jane, and C. Glenn Begley PMCID: PMC298714 Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells Przemyslaw Blyszczuk, Jaroslaw Czyz, Gabriela Kania, Martin Wagner, Ursula Roll, Luc St-Onge, and Anna M. Wobus PMCID: PMC298715 Molecular features of adult mouse small intestinal epithelial progenitors Thaddeus S. Stappenbeck, Jason C. Mills, and Jeffrey I. Gordon PMCID: PMC298716 The C-terminal domain of myosin-like protein 1 (Mlp1p) is a docking site for heterogeneous nuclear ribonucleoproteins that are required for mRNA export Deanna M. Green, Christie P. Johnson, Henry Hagan, and Anita H. Corbett PMCID: PMC298717 Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2 K. C. Leung, N. Doyle, M. Ballesteros, K. Sjogren, C. K. W. Watts, T. H. Low, G. M. Leong, R. J. M. Ross, and K. K. Y. Ho PMCID: PMC298718 Bcl-xL overexpression blocks bax-mediated mitochondrial contact site formation and apoptosis in rod photoreceptors of lead-exposed mice Lihua He, Guy A. Perkins, Ann T. Poblenz, Jeffrey B. Harris, Michael Hung, Mark H. Ellisman, and Donald A. Fox PMCID: PMC298719 Identification of nucleocytoplasmic cycling as a remote sensor in cellular signaling by databased modeling I. Swameye, T. G. Müller, J. Timmer, O. Sandra, and U. Klingmüller PMCID: PMC298720 Involvement of bone morphogenetic protein 4 (BMP-4) in pituitary prolactinoma pathogenesis through a Smad/estrogen receptor crosstalk Marcelo Páez-Pereda, Damiana Giacomini, Damian Refojo, Alberto Carbia Nagashima, Ursula Hopfner, Yvonne Grübler, Alberto Chervin, Victoria Goldberg, Rodolfo Goya, Shane T. Hentges, Malcolm J. Low, Florian Holsboer, Günter K. Stalla, and Eduardo Arzt PMCID: PMC298721 Developmental Biology Requirement of the calcineurin subunit gene canB2 for indirect flight muscle formation in Drosophila Kathleen Gajewski, Jianbo Wang, Jeffery D. Molkentin, Elizabeth H. Chen, Eric N. Olson, and Robert A. Schulz PMCID: PMC298722 Ecology Global variation in terrestrial conservation costs, conservation benefits, and unmet conservation needs Andrew Balmford, Kevin J. Gaston, Simon Blyth, Alex James, and Val Kapos PMCID: PMC298723 Reduction of cholera in Bangladeshi villages by simple filtration Rita R. Colwell, Anwar Huq, M. Sirajul Islam, K. M. A. Aziz, M. Yunus, N. Huda Khan, A. Mahmud, R. Bradley Sack, G. B. Nair, J. Chakraborty, David A. Sack, and E. Russek-Cohen PMCID: PMC298724 Evolution Placental mammal diversification and the Cretaceous–Tertiary boundary Mark S. Springer, William J. Murphy, Eduardo Eizirik, and Stephen J. O'Brien PMCID: PMC298725 Reciprocal chromosome painting among human, aardvark, and elephant (superorder Afrotheria) reveals the likely eutherian ancestral karyotype F. Yang, E. Z. Alkalaeva, P. L. Perelman, A. T. Pardini, W. R. Harrison, P. C. M. O'Brien, B. Fu, A. S. Graphodatsky, M. A. Ferguson-Smith, and T. J. Robinson PMCID: PMC298726 From the Cover:
Plant-like traits associated with metabolism of Trypanosoma parasites Véronique Hannaert, Emma Saavedra, Francis Duffieux, Jean-Pierre Szikora, Daniel J. Rigden, Paul A. M. Michels, and Fred R. Opperdoes PMCID: PMC298727 Parallel changes in gene expression after 20,000 generations of evolution in Escherichia coli Tim F. Cooper, Daniel E. Rozen, and Richard E. Lenski PMCID: PMC298728 Genetic diversity, asymmetrical aggression, and recognition in a widespread invasive species Neil D. Tsutsui, Andrew V. Suarez, and Richard K. Grosberg PMCID: PMC298729 Hox gene clusters in the Indonesian coelacanth, Latimeria menadoensis Esther G. L. Koh, Kevin Lam, Alan Christoffels, Mark V. Erdmann, Sydney Brenner, and Byrappa Venkatesh PMCID: PMC298730 Genetic biases for showy males: Are some genetic systems especially conducive to sexual selection? Hudson Kern Reeve and David W. Pfennig PMCID: PMC298731 An evolutionary scenario for the transition to undifferentiated multicellularity Thomas Pfeiffer and Sebastian Bonhoeffer PMCID: PMC298732 INAUGURAL ARTICLE by a Recently Elected Academy Member: Emergence and evolution of Vibrio cholerae O139 Shah M. Faruque, David A. Sack, R. Bradley Sack, Rita R. Colwell, Yoshifumi Takeda, and G. Balakrish Nair PMCID: PMC298768 Genetics Discovery of the breast cancer gene BASE using a molecular approach to enrich for genes encoding membrane and secreted proteins Kristi A. Egland, James J. Vincent, Robert Strausberg, Byungkook Lee, and Ira Pastan PMCID: PMC298733 Chromatin insulation by a transcriptional activator Nathan B. Sutter, David Scalzo, Steven Fiering, Mark Groudine, and David I. K. Martin PMCID: PMC298734 Promoters of the murine embryonic β-like globin genes Ey and βh1 do not compete for interaction with the β-globin locus control region Xiao Hu, Michael Bulger, Julia N. Roach, Susan K. Eszterhas, Emmanuel Olivier, Eric E. Bouhassira, Mark T. Groudine, and Steven Fiering PMCID: PMC298735 Strikingly higher frequency in centenarians and twins of mtDNA mutation causing remodeling of replication origin in leukocytes Jin Zhang, Jordi Asin-Cayuela, Jennifer Fish, Yuichi Michikawa, Massimiliano Bonafé, Fabiola Olivieri, Giuseppe Passarino, Giovanna De Benedictis, Claudio Franceschi, and Giuseppe Attardi PMCID: PMC298736 A segmental nearest neighbor normalization and gene identification method gives superior results for DNA-array analysis He Yang, Hadar Haddad, Christopher Tomas, Keith Alsaker, and E. Terry Papoutsakis PMCID: PMC298737 Modular organization of cellular networks Alexander W. Rives and Timothy Galitski PMCID: PMC298738 Stabilization of perfect and imperfect tandem repeats by single-strand DNA exonucleases Vladimir V. Feschenko, Luis A. Rajman, and Susan T. Lovett PMCID: PMC298739 Comparison of mouse and human genomes followed by experimental verification yields an estimated 1,019 additional genes Roderic Guigó, Emmanouil T. Dermitzakis, Pankaj Agarwal, Chris P. Ponting, Genís Parra, Alexandre Reymond, Josep F. Abril, Evan Keibler, Robert Lyle, Catherine Ucla, Stylianos E. Antonarakis, and Michael R. Brent PMCID: PMC298740 The mouse organellar biogenesis mutant buff results from a mutation in Vps33a, a homologue of yeast vps33 and Drosophila carnation Tamio Suzuki, Naoki Oiso, Rashi Gautam, Edward K. Novak, Jean-Jacques Panthier, P. G. Suprabha, Thomas Vida, Richard T. Swank, and Richard A. Spritz PMCID: PMC298741 Understanding missense mutations in the BRCA1 gene: An evolutionary approach Melissa A. Fleming, John D. Potter, Christina J. Ramirez, Gary K. Ostrander, and Elaine A. Ostrander PMCID: PMC298742 Immunology Innate and acquired immunity intersect in a global view of the acute-phase response Joo-Yeon Yoo and Stephen Desiderio PMCID: PMC298743 Optimized expression and specific activity of IL-12 by directed molecular evolution Steven R. Leong, Jean C. C. Chang, Randal Ong, Glenn Dawes, Willem P. C. Stemmer, and Juha Punnonen PMCID: PMC298744 Chemogenomic identification of Ref-1/AP-1 as a therapeutic target for asthma Cu Nguyen, Jia-Ling Teo, Akihisa Matsuda, Masakatsu Eguchi, Emil Y. Chi, William R. Henderson, Jr., and Michael Kahn PMCID: PMC298745 Activation of human eosinophils through leukocyte immunoglobulin-like receptor 7 Nicodemus Tedla, Christianne Bandeira-Melo, Paolo Tassinari, David E. Sloane, Mary Samplaski, David Cosman, Luis Borges, Peter F. Weller, and Jonathan P. Arm PMCID: PMC298746 Definitive separation of graft-versus-leukemia- and graft-versus-host-specific CD4+ T cells by virtue of their receptor β loci sequences J. Michálek, R. H. Collins, H. P. Durrani, P. Václavková, L. E. Ruff, D. C. Douek, and E. S. Vitetta PMCID: PMC298747 Competition for self ligands restrains homeostatic proliferation of naive CD4 T cells Christina T. Moses, Kristen M. Thorstenson, Stephen C. Jameson, and Alexander Khoruts PMCID: PMC298748 HLA-G gene repression is reversed by demethylation Philippe Moreau, Gaël Mouillot, Philippe Rousseau, Céline Marcou, Jean Dausset, and Edgardo D. Carosella PMCID: PMC298749 Without peripheral interference, thymic deletion is mediated in a cohort of double-positive cells without classical activation Yifan Zhan, Jared F. Purton, Dale I. Godfrey, Timothy J. Cole, William R. Heath, and Andrew M. Lew PMCID: PMC298750 The role of nuclear factor-κB essential modulator (NEMO) in B cell development and survival Shinyop Kim, Ross N. A. La Motte-Mohs, Dorothea Rudolph, Juan Carlos Zúñiga-Pflücker, and Tak W. Mak PMCID: PMC298751 Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice Yoshiko Akamatsu, Robert Monroe, Darryll D. Dudley, Sheryl K. Elkin, Frank Gärtner, Sadiqur R. Talukder, Yousuke Takahama, Frederick W. Alt, Craig H. Bassing, and Marjorie A. Oettinger PMCID: PMC298752 Medical Sciences Essential role for Atox1 in the copper-mediated intracellular trafficking of the Menkes ATPase Iqbal Hamza, Joseph Prohaska, and Jonathan D. Gitlin PMCID: PMC298753 Components of the Rb pathway are critical targets of UV mutagenesis in a murine melanoma model Karuppiah Kannan, Norman E. Sharpless, Jin Xu, Ronan C. O'Hagan, Marcus Bosenberg, and Lynda Chin PMCID: PMC298754 A critical role for PPARα-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: Modulation by dietary fat content Brian N. Finck, Xianlin Han, Michael Courtois, Franck Aimond, Jeanne M. Nerbonne, Attila Kovacs, Richard W. Gross, and Daniel P. Kelly PMCID: PMC298755 Quantitative imaging of the T cell antitumor response by positron-emission tomography Purnima Dubey, Helen Su, Nona Adonai, Shouying Du, Antonio Rosato, Jonathan Braun, Sanjiv S. Gambhir, and Owen N. Witte PMCID: PMC298756 Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis Rainer Spanbroek, Rolf Gräbner, Katharina Lötzer, Markus Hildner, Anja Urbach, Katharina Rühling, Michael P. W. Moos, Brigitte Kaiser, Tina U. Cohnert, Thorsten Wahlers, Arthur Zieske, Gabriele Plenz, Horst Robenek, Peter Salbach, Hartmut Kühn, Olof Rådmark, Bengt Samuelsson, and Andreas J. R. Habenicht PMCID: PMC298757 Crowding-dependent production of colony-stimulating factors by cultured syngeneic or allogeneic hematopoietic cells Donald Metcalf, Ladina Di Rago, and Sandra Mifsud PMCID: PMC298758 Growth hormone-releasing hormone (GHRH) antagonists inhibit the proliferation of androgen-dependent and -independent prostate cancers Markus Letsch, Andrew V. Schally, Rebeca Busto, Ana M. Bajo, and Jozsef L. Varga PMCID: PMC298759 Two Hsp70 family members expressed in atherosclerotic lesions Zhihua Han, Quynh A. Truong, Shirley Park, and Jan L. Breslow PMCID: PMC298760 Deficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient mice Emily L. Willner, Bryan Tow, Kimberly K. Buhman, Martha Wilson, David A. Sanan, Lawrence L. Rudel, and Robert V. Farese, Jr. PMCID: PMC298761 PPARδ is a very low-density lipoprotein sensor in macrophages Ajay Chawla, Chih-Hao Lee, Yaacov Barak, Weimin He, John Rosenfeld, Debbie Liao, Jungyeob Han, Heonjoong Kang, and Ronald M. Evans PMCID: PMC298762 Lectin-like oxidized LDL receptor-1 is a cell-adhesion molecule involved in endotoxin-induced inflammation Megumi Honjo, Kayo Nakamura, Kenji Yamashiro, Junichi Kiryu, Hidenobu Tanihara, Leslie M. McEvoy, Yoshihito Honda, Eugene C. Butcher, Tomoh Masaki, and Tatsuya Sawamura PMCID: PMC298763 Microbiology CTXΦ-independent production of the RS1 satellite phage by Vibrio cholerae Shah M. Faruque, M. Kamruzzaman, Asadulghani, David A. Sack, John J. Mekalanos, and G. Balakrish Nair PMCID: PMC298764 Determination of the transcriptome of Vibrio cholerae during intraintestinal growth and midexponential phase in vitro Qing Xu, Michelle Dziejman, and John J. Mekalanos PMCID: PMC298765 Distinct gene expression profiles characterize the histopathological stages of disease in Helicobacter-induced mucosa-associated lymphoid tissue lymphoma Anne Mueller, Jani O'Rourke, Jan Grimm, Karen Guillemin, Michael F. Dixon, Adrian Lee, and Stanley Falkow PMCID: PMC298766 Abrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells Neeltje A. Kootstra, Carsten Münk, Nina Tonnu, Nathaniel R. Landau, and Inder M. Verma PMCID: PMC298767 INAUGURAL ARTICLE by a Recently Elected Academy Member: Emergence and evolution of Vibrio cholerae O139 Shah M. Faruque, David A. Sack, R. Bradley Sack, Rita R. Colwell, Yoshifumi Takeda, and G. Balakrish Nair PMCID: PMC298768 Transcriptional and posttranscriptional control of hepatitis B virus gene expression Susan L. Uprichard, Stefan F. Wieland, Alana Althage, and Francis V. Chisari PMCID: PMC298769 The genome sequence of Clostridium tetani, the causative agent of tetanus disease Holger Brüggemann, Sebastian Bäumer, Wolfgang Florian Fricke, Arnim Wiezer, Heiko Liesegang, Iwona Decker, Christina Herzberg, Rosa Martínez-Arias, Rainer Merkl, Anke Henne, and Gerhard Gottschalk PMCID: PMC298770 Neuroscience Metabotropic mGlu5 receptors regulate adenosine A2A receptor signaling Akinori Nishi, Feng Liu, Seiichiro Matsuyama, Miho Hamada, Hideho Higashi, Angus C. Nairn, and Paul Greengard PMCID: PMC298771 The hippocampus mediates glucocorticoid-induced impairment of spatial memory retrieval: Dependence on the basolateral amygdala Benno Roozendaal, Qyana K. Griffith, Jason Buranday, Dominique J.-F. de Quervain, and James L. McGaugh PMCID: PMC298772 Eye opening induces a rapid dendritic localization of PSD-95 in central visual neurons Akira Yoshii, Morgan H. Sheng, and Martha Constantine-Paton PMCID: PMC298773 Developmental loss of miniature N-methyl-d-aspartate receptor currents in NR2A knockout mice Matthew Townsend, Akira Yoshii, M. Mishina, and Martha Constantine-Paton PMCID: PMC298774 Adenosine receptor blockade reverses hypophagia and enhances locomotor activity of dopamine-deficient mice Douglas S. Kim and Richard D. Palmiter PMCID: PMC298775 Photochemical gating of heterologous ion channels: Remote control over genetically designated populations of neurons Boris V. Zemelman, Nasri Nesnas, Georgia A. Lee, and Gero Miesenböck PMCID: PMC298776 GABAergic synapses made by a retinal dopaminergic neuron Massimo Contini and Elio Raviola PMCID: PMC298777 Transplanted bone marrow generates new neurons in human brains Éva Mezey, Sharon Key, Georgia Vogelsang, Ildiko Szalayova, G. David Lange, and Barbara Crain PMCID: PMC298778 Contrasting roles of axonal (pyramidal cell) and dendritic (interneuron) electrical coupling in the generation of neuronal network oscillations Roger D. Traub, Isabel Pais, Andrea Bibbig, Fiona E. N. LeBeau, Eberhard H. Buhl, Sheriar G. Hormuzdi, Hannah Monyer, and Miles A. Whittington PMCID: PMC298779 No hypothermic response to serotonin in 5-HT7 receptor knockout mice P. B. Hedlund, P. E. Danielson, E. A. Thomas, K. Slanina, M. J. Carson, and J. G. Sutcliffe PMCID: PMC298780 Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: A magnetic resonance microscopy and stereologic analysis Jeffrey M. Redwine, Barry Kosofsky, Russell E. Jacobs, Dora Games, John F. Reilly, John H. Morrison, Warren G. Young, and Floyd E. Bloom PMCID: PMC298781 Course of illness, hippocampal function, and hippocampal volume in major depression Glenda M. MacQueen, Stephanie Campbell, Bruce S. McEwen, Kathryn Macdonald, Shigeko Amano, Russell T. Joffe, Claude Nahmias, and L. Trevor Young PMCID: PMC298782 Endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice Lei Wang, Jie Liu, Judith Harvey-White, Andreas Zimmer, and George Kunos PMCID: PMC298783 Working memory and fear conditioning Ronald McKell Carter, Constanze Hofstötter, Naotsugu Tsuchiya, and Christof Koch PMCID: PMC298784 Suppression of cortical representation through backward conditioning Shaowen Bao, Vincent T. Chan, Li I. Zhang, and Michael M. Merzenich PMCID: PMC298785 A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission Angela Ho, Wade Morishita, Robert E. Hammer, Robert C. Malenka, and Thomas C. Südhof PMCID: PMC298786 Understanding neural system dynamics through task modulation and measurement of functional MRI amplitude, latency, and width P. S. F. Bellgowan, Z. S. Saad, and P. A. Bandettini PMCID: PMC298787 Pharmacology From the Cover:
Beneficial effects of antioxidants and l-arginine on oxidation-sensitive gene expression and endothelial NO synthase activity at sites of disturbed shear stress Filomena de Nigris, Lilach O. Lerman, Sharon Williams Ignarro, Giacomo Sica, Amir Lerman, Wulf Palinski, Louis J. Ignarro, and Claudio Napoli PMCID: PMC298788 Release of C-type natriuretic peptide accounts for the biological activity of endothelium-derived hyperpolarizing factor Sharmila D. Chauhan, Holger Nilsson, Amrita Ahluwalia, and Adrian J. Hobbs PMCID: PMC298789 Physiology The maltase-glucoamylase gene: Common ancestry to sucrase-isomaltase with complementary starch digestion activities Buford L. Nichols, Stephen Avery, Partha Sen, Dallas M. Swallow, Dagmar Hahn, and Erwin Sterchi PMCID: PMC298790 Lower blood glucose, hyperglucagonemia, and pancreatic α cell hyperplasia in glucagon receptor knockout mice R. W. Gelling, X. Q. Du, D. S. Dichmann, J. Rømer, H. Huang, L. Cui, S. Obici, B. Tang, J. J. Holst, C. Fledelius, P. B. Johansen, L. Rossetti, L. A. Jelicks, P. Serup, E. Nishimura, and M. J. Charron PMCID: PMC298791 Plant Biology From the Cover:
Extensive and specific responses of a eukaryote to bacterial quorum-sensing signals Ulrike Mathesius, Susan Mulders, Mengsheng Gao, Max Teplitski, Gustavo Caetano-Anollés, Barry G. Rolfe, and Wolfgang D. Bauer PMCID: PMC298792 Interactions among three distinct CesA proteins essential for cellulose synthesis Neil G. Taylor, Rhian M. Howells, Alison K. Huttly, Kate Vickers, and Simon R. Turner PMCID: PMC298793 Blue light activates calcium-permeable channels in Arabidopsis mesophyll cells via the phototropin signaling pathway Sonja Stoelzle, Takatoshi Kagawa, Masamitsu Wada, Rainer Hedrich, and Petra Dietrich PMCID: PMC298794 Corrections Proc Natl Acad Sci U S A. 2003 February 4; 100(3): 1462. Published online 2003 January 17. doi: 10.1073/pnas.0337666100.PMCID: PMC298671 Corrects: Francis Fabre, et al. Alternate pathways involving Sgs1/Top3, Mus81/ Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication. Proc Natl Acad Sci U S A. 2002 December 24; 99(26): 16887–16892. Proc Natl Acad Sci U S A. 2003 February 4; 100(3): 1462. Published online 2003 January 17. doi: 10.1073/pnas.0337734100.PMCID: PMC298672 Corrects: Tapan K. Bera, et al. POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer. Proc Natl Acad Sci U S A. 2002 December 24; 99(26): 16975–16980. |
