| | This journal provides immediate access to some articles. Commentaries Glycosylphosphatidylinositol biosynthesis validated as a drug
target for African sleeping sickness Michael A. J. Ferguson PMCID: PMC34041 Mice, microarrays, and the genetic diversity of the brain Daniel H. Geschwind PMCID: PMC34042 Breaking the affinity ceiling for antibodies and T
cell receptors Jefferson Foote and Herman N. Eisen PMCID: PMC34043 Viral interference with IL-1 and Toll signaling Charles Janeway, Jr. and Ruslan Medzhitov PMCID: PMC34044 Hominoid systematics: The soft evidence David Pilbeam PMCID: PMC34045 Physical Sciences Applied Physical Sciences Capacitance cytometry: Measuring biological cells one by one L. L. Sohn, O. A. Saleh, G. R. Facer, A. J. Beavis, R. S. Allan, and D. A. Notterman PMCID: PMC27083 Chemistry Microbial iron transport via a siderophore shuttle: A
membrane ion transport paradigm Alain Stintzi, Carmen Barnes, Jide Xu, and Kenneth N. Raymond PMCID: PMC27084 Physics From the Cover:
Temperature, ordering, and equilibrium with time-dependent
confining forces J. P. Schiffer, M. Drewsen, J. S. Hangst, and L. Hornekær PMCID: PMC27085 Biological Sciences Applied Biological Sciences Directed evolution of antibody fragments with monovalent
femtomolar antigen-binding affinity Eric T. Boder, Katarina S. Midelfort, and K. Dane Wittrup PMCID: PMC27086 Biochemistry Elucidating the mechanism of familial amyloidosis– Finnish
type: NMR studies of human gelsolin domain 2 Steven L. Kazmirski, Mark J. Howard, Rivka L. Isaacson, and Alan R. Fersht PMCID: PMC27087 Molecular mechanisms underlying differential odor responses of a
mouse olfactory receptor Wely B. Floriano, Nagarajan Vaidehi, William A. Goddard, III, Michael S. Singer, and Gordon M. Shepherd PMCID: PMC27088 Quantitative, chemically specific imaging of selenium
transformation in plants Ingrid J. Pickering, Roger C. Prince, David E. Salt, and Graham N. George PMCID: PMC27089 Crystal structures of bovine milk xanthine dehydrogenase and
xanthine oxidase: Structure-based mechanism of conversion Cristofer Enroth, Bryan T. Eger, Ken Okamoto, Tomoko Nishino, Takeshi Nishino, and Emil F. Pai PMCID: PMC27090 Unraveling the mechanism of the lactose permease of
Escherichia coli Miklós Sahin-Tóth, Arthur Karlin, and H. Ronald Kaback PMCID: PMC27091 Old Yellow Enzyme: Stepwise reduction of nitro-olefins and
catalysis of aci-nitro tautomerization Younus Meah and Vincent Massey PMCID: PMC27092 Position-specific trapping of topoisomerase I–DNA cleavage
complexes by intercalated benzo[a]- pyrene diol
epoxide adducts at the 6-amino group of adenine Yves Pommier, Gary S. Laco, Glenda Kohlhagen, Jane M. Sayer, Heiko Kroth, and Donald M. Jerina PMCID: PMC27093 An initiation element in the yeast CUP1 promoter
is recognized by RNA polymerase II in the absence of TATA
box-binding protein if the DNA is negatively supercoiled Benoit P. Leblanc, Craig J. Benham, and David J. Clark PMCID: PMC27094 Identification of a third distinct estrogen receptor and
reclassification of estrogen receptors in teleosts Mary Beth Hawkins, Joseph W. Thornton, David Crews, James K. Skipper, Alyssa Dotte, and Peter Thomas PMCID: PMC27095 N-terminal transcriptional activation domain of LZIP comprises
two LxxLL motifs and the Host Cell Factor-1 binding motif Randy L. Luciano and Angus C. Wilson PMCID: PMC27096 Human recombinant soluble guanylyl cyclase: Expression,
purification, and regulation Yu-Chen Lee, Emil Martin, and Ferid Murad PMCID: PMC27097 CXR, a chicken xenobiotic-sensing orphan nuclear receptor, is
related to both mammalian pregnane X receptor (PXR) and constitutive androstane receptor (CAR) Christoph Handschin, Michael Podvinec, and Urs A. Meyer PMCID: PMC27098 Biophysics How does a β-hairpin fold/unfold? Competition between
topology and heterogeneity in a solvable model Chinlin Guo, Herbert Levine, and David A. Kessler PMCID: PMC27099 Folding simulations of a three-stranded antiparallel
β-sheet peptide Philippe Ferrara and Amedeo Caflisch PMCID: PMC27100 Energetics of the interaction between water and the helical
peptide group and its role in determining helix propensities Franc Avbelj, Peizhi Luo, and Robert L. Baldwin PMCID: PMC27101 Shape anisotropy of a single random-walk polymer Charbel Haber, Sami Alom Ruiz, and Denis Wirtz PMCID: PMC27102 Absence of stable intermediates on the folding pathway
of barnase Jiro Takei, Rui-Ai Chu, and Yawen Bai PMCID: PMC27103 Unbinding process of adsorbed proteins under external stress
studied by atomic force microscopy spectroscopy C. Gergely, J.-C. Voegel, P. Schaaf, B. Senger, M. Maaloum, J. K. H. Hörber, and J. Hemmerlé PMCID: PMC27104 Femtosecond dynamics of the forbidden carotenoid S1
state in light-harvesting complexes of purple bacteria observed after
two-photon excitation Peter J. Walla, Patricia A. Linden, Chao-Ping Hsu, Gregory D. Scholes, and Graham R. Fleming PMCID: PMC27105 Cell Biology Capacitance cytometry: Measuring biological cells one by one L. L. Sohn, O. A. Saleh, G. R. Facer, A. J. Beavis, R. S. Allan, and D. A. Notterman PMCID: PMC27083 Tid1/Rdh54 promotes colocalization of Rad51 and Dmc1 during
meiotic recombination Miki Shinohara, Stephen L. Gasior, Douglas K. Bishop, and Akira Shinohara PMCID: PMC27106 Combinatorial roles for pRB, p107, and p130 in E2F-mediated cell
cycle control Marie Classon, Sofie Salama, Carolyn Gorka, Roseann Mulloy, Pascal Braun, and Ed Harlow PMCID: PMC27107 Opposing roles of pRB and p107 in adipocyte differentiation Marie Classon, Brian K. Kennedy, Roseann Mulloy, and Ed Harlow PMCID: PMC27108 Modulation of Akt kinase activity by binding to Hsp90 Saori Sato, Naoya Fujita, and Takashi Tsuruo PMCID: PMC27109 Developmental Biology sqv-3, -7, and -8, a
set of genes affecting morphogenesis in
Caenorhabditis elegans, encode
enzymes required for glycosaminoglycan biosynthesis Dorota A. Bulik, Ge Wei, Hidenao Toyoda, Akiko Kinoshita-Toyoda, W. Ross Waldrip, Jeffrey D. Esko, Phillips W. Robbins, and Scott B. Selleck PMCID: PMC27110 Function of bicoid and hunchback
homologs in the basal cyclorrhaphan fly
Megaselia (Phoridae) Michael Stauber, Heike Taubert, and Urs Schmidt-Ott PMCID: PMC27111 Ecology Predicting species diversity in tropical forests Joshua B. Plotkin, Matthew D. Potts, Douglas W. Yu, Sarayudh Bunyavejchewin, Richard Condit, Robin Foster, Stephen Hubbell, James LaFrankie, N. Manokaran, Lee Hua Seng, Raman Sukumar, Martin A. Nowak, and Peter S. Ashton PMCID: PMC27112 Evolution Postsymbiotic plasmid acquisition and evolution of the
repA1-replicon in Buchnera aphidicola Roeland C. H. J. Van Ham, Fernando González-Candelas, Francisco J. Silva, Beatriz Sabater, Andrés Moya, and Amparo Latorre PMCID: PMC27113 Adaptive evolution of a candidate gene for aging in
Drosophila Paul S. Schmidt, David D. Duvernell, and Walter F. Eanes PMCID: PMC27114 Purifying selection and birth-and-death evolution in the
ubiquitin gene family Masatoshi Nei, Igor B. Rogozin, and Helen Piontkivska PMCID: PMC27115 Genetics Mutational inactivation of the proapoptotic gene
BAX confers selective advantage during tumor
clonal evolution Yurij Ionov, Hiroyuki Yamamoto, Stanislaw Krajewski, John C. Reed, and Manuel Perucho PMCID: PMC27116 Genomic organization of α1 and β1 subunits of the mammalian
soluble guanylyl cyclase genes I. G. Sharina, J. S. Krumenacker, E. Martin, and F. Murad PMCID: PMC27117 Roles of a conserved arginine residue of DsbB in linking protein
disulfide-bond-formation pathway to the respiratory chain of
Escherichia coli Hiroshi Kadokura, Martin Bader, Hongping Tian, James C. A. Bardwell, and Jon Beckwith PMCID: PMC27118 Position-dependent activity of α-fetoprotein enhancer element
III in the adult liver is due to negative regulation David K. Peyton, Tennore Ramesh, and Brett T. Spear PMCID: PMC27119 Robust gut-specific gene expression in transgenic Aedes
aegypti mosquitoes Luciano A. Moreira, Marten J. Edwards, Faisal Adhami, Nijole Jasinskiene, Anthony A. James, and Marcelo Jacobs-Lorena PMCID: PMC27120 Borrelia burgdorferi periplasmic flagella have
both skeletal and motility functions Mohammed Abdul Motaleb, Linda Corum, James L. Bono, Abdallah F. Elias, Patricia Rosa, D. Scott Samuels, and Nyles W. Charon PMCID: PMC27121 Immunology Diverse roles of the tumor necrosis factor family member TRANCE
in skeletal physiology revealed by TRANCE deficiency and partial
rescue by a lymphocyte-expressed TRANCE transgene Nacksung Kim, Paul R. Odgren, Dong-Ku Kim, Sandy C. Marks, Jr., and Yongwon Choi PMCID: PMC27122 Fully competent dendritic cells as inducers of T cell anergy
in autoimmunity Sonia Quaratino, Linda P. Duddy, and Marco Londei PMCID: PMC27123 Strategy for monitoring T cell responses to NY-ESO-1 in patients
with any HLA class I allele Sacha Gnjatic, Yasuhiro Nagata, Elke Jäger, Elisabeth Stockert, Srinivas Shankara, Bruce L. Roberts, Gail P. Mazzara, Sang Yull Lee, P. Rod Dunbar, Bo Dupont, Vincenzo Cerundolo, Gerd Ritter, Yao-Tseng Chen, Alexander Knuth, and Lloyd J. Old PMCID: PMC27124 INAUGURAL ARTICLE by a Recently Elected Academy Member: T-cell receptor antagonists induce Vav phosphorylation by
selective activation of Fyn kinase Jianyong Huang, Darcie Tilly, Amnon Altman, Katsuji Sugie, and Howard M. Grey PMCID: PMC27125 From the Cover:
Antibodies have the intrinsic capacity to destroy antigens Anita D. Wentworth, Lyn H. Jones, Paul Wentworth, Jr., Kim D. Janda, and Richard A. Lerner PMCID: PMC27126 Medical Sciences Implications of EPHB6, EFNB2, and
EFNB3 expressions in human neuroblastoma Xao X. Tang, Huaqing Zhao, Marjorie E. Robinson, Brian Cohen, Avital Cnaan, Wendy London, Susan L. Cohn, Nai-Kong V. Cheung, Garrett M. Brodeur, Audrey E. Evans, and Naohiko Ikegaki PMCID: PMC27127 A first trial of retrospective collaboration for positional
cloning in complex inheritance: Assay of the cytokine region on chromosome 5 by the Consortium on Asthma Genetics (COAG) C. Lonjou, K. Barnes, H. Chen, W. O. C. M. Cookson, K. A. Deichmann, I. P. Hall, J. W. Holloway, T. Laitinen, L. J. Palmer, M. Wjst, and N. E. Morton PMCID: PMC27128 Antiretroviral resistance during successful therapy of HIV type
1 infection J. Martinez-Picado, M. P. DePasquale, N. Kartsonis, G. J. Hanna, J. Wong, D. Finzi, E. Rosenberg, H. F. Günthard, L. Sutton, A. Savara, C. J. Petropoulos, N. Hellmann, B. D. Walker, D. D. Richman, R. Siliciano, and R. T. D'Aquila PMCID: PMC27129 Microglial activation precedes acute neurodegeneration in
Sandhoff disease and is suppressed by bone marrow transplantation Ryuichi Wada, Cynthia J. Tifft, and Richard L. Proia PMCID: PMC27130 Enrichment for murine keratinocyte stem cells based on cell
surface phenotype Hiroaki Tani, Rebecca
J. Morris, and Pritinder Kaur PMCID: PMC27131 Influence of follicular dendritic cells on decay of HIV during
antiretroviral therapy William S. Hlavacek, Nikolaos I. Stilianakis, Daan W. Notermans, Sven A. Danner, and Alan S. Perelson PMCID: PMC27132 Regulation of vascular endothelial growth factor (VEGF) gene
transcription by estrogen receptors α and β Michael D. Mueller, Jean-Louis Vigne, Alexander Minchenko, Dan I. Lebovic, Dale C. Leitman, and Robert N. Taylor PMCID: PMC27133 Rapid induction of senescence in human cervical carcinoma cells Edward C. Goodwin, Eva Yang, Chan-Jae Lee, Han-Woong Lee, Daniel DiMaio, and Eun-Seong Hwang PMCID: PMC27134 Retrovirus-mediated gene transfer of MLL-ELL
transforms primary myeloid progenitors and causes acute myeloid
leukemias in mice Catherine Lavau, Roger T. Luo, Changchun Du, and Michael J. Thirman PMCID: PMC27135 Effects of ligand activation of peroxisome proliferator-activated
receptor γ in human prostate cancer Elisabetta Mueller, Matthew Smith, Pasha Sarraf, Todd Kroll, Anita Aiyer, Donald S. Kaufman, William Oh, George Demetri, William D. Figg, Xiao-Ping Zhou, Charis Eng, Bruce M. Spiegelman, and Philip W. Kantoff PMCID: PMC27136 Microbiology Microbial iron transport via a siderophore shuttle: A
membrane ion transport paradigm Alain Stintzi, Carmen Barnes, Jide Xu, and Kenneth N. Raymond PMCID: PMC27084 The role of cdc2 in the expression of herpes simplex virus genes Sunil J. Advani, Ralph R. Weichselbaum, and Bernard Roizman PMCID: PMC27137 The essential protein encoded by the UL31 gene of
herpes simplex virus 1 depends for its stability on the presence of
UL34 protein Guo-Jie Ye and Bernard Roizman PMCID: PMC27138 Contribution of Salmonella typhimurium type III
secretion components to needle complex formation Tyler G. Kimbrough and Samuel I. Miller PMCID: PMC27139 Neurobiology Cerebral protein synthesis in a genetic mouse model
of phenylketonuria Carolyn Beebe Smith and Julia Kang PMCID: PMC27140 Modifications of retinal neurons in a mouse model of
retinitis pigmentosa Enrica Strettoi and Vincenzo Pignatelli PMCID: PMC27141 An approach to probe some neural systems interaction by
functional MRI at neural time scale down to milliseconds Seiji Ogawa, Tso-Ming Lee, Ray Stepnoski, Wei Chen, Xiao-Hong Zhu, and Kamil Ugurbil PMCID: PMC27142 Prenatal stress produces learning deficits associated with an
inhibition of neurogenesis in the hippocampus V. Lemaire, M. Koehl, M. Le Moal, and D. N. Abrous PMCID: PMC27143 From the Cover:
Regional and strain-specific gene expression mapping in the adult
mouse brain Rickard Sandberg, Rie Yasuda, Daniel G. Pankratz, Todd A. Carter, Jo A. Del Rio, Lisa Wodicka, Mark Mayford, David J. Lockhart, and Carrolee Barlow PMCID: PMC27144 Leptin as a modulator of sweet taste sensitivities in mice Kirio Kawai, Kumiko Sugimoto, Kiyohito Nakashima, Hirohito Miura, and Yuzo Ninomiya PMCID: PMC27145 Measuring the thickness of the human cerebral cortex from
magnetic resonance images Bruce Fischl and Anders M. Dale PMCID: PMC27146 Experimental diabetes in rats causes hippocampal dendritic and
synaptic reorganization and increased glucocorticoid reactivity
to stress Ana María Magariños and Bruce S. McEwen PMCID: PMC27147 Molecular determinants of coordinated proton and zinc inhibition
of N-methyl-d-aspartate NR1/NR2A receptors Chian-Ming Low, Fang Zheng, Polina Lyuboslavsky, and Stephen F. Traynelis PMCID: PMC27148 Surgically created neural pathways mediate visual pattern
discrimination Douglas O. Frost, Denis Boire, Guy Gingras, and Maurice Ptito PMCID: PMC27149 Regulation and localization of tyrosine216
phosphorylation of glycogen synthase kinase-3β in cellular and
animal models of neuronal degeneration Ratan V. Bhat, Jason Shanley, Maryann P. Correll, William E. Fieles, Richard A. Keith, Clay W. Scott, and Chi-Ming Lee PMCID: PMC27150 Physiology High phosphorylation efficiency and depression of uncoupled
respiration in mitochondria under hypoxia Erich Gnaiger, Gabriela Méndez, and Steven C. Hand PMCID: PMC27151 The proliferative and antiapoptotic effects of substance
P are facilitated by formation of a β-arrestin-dependent scaffolding
complex K. A. DeFea, Z. D. Vaughn, E. M. O'Bryan, D. Nishijima, O. Déry, and N. W. Bunnett PMCID: PMC27152 Alternative splicing of the rat sodium/bile acid transporter
changes its cellular localization and transport properties Konstantinos N. Lazaridis, Pam Tietz, Ting Wu, Sertac Kip, Paul A. Dawson, and Nicholas F. LaRusso PMCID: PMC27153 Plant Biology Protection and storage of chlorophyll in
overwintering evergreens Adam M. Gilmore and Marilyn C. Ball PMCID: PMC27154 An alternative pathway to β-carotene formation in plant
chromoplasts discovered by map-based cloning of Beta and
old-gold color mutations in tomato Gil Ronen, Lea Carmel-Goren, Dani Zamir, and Joseph Hirschberg PMCID: PMC27155 Glutathione biosynthesis in Arabidopsis trichome
cells Gloria Gutiérrez-Alcalá, Cecilia Gotor, Andreas J. Meyer, Mark Fricker, José M. Vega, and Luis C. Romero PMCID: PMC27156 Symbiosis-specific expression of Rhizobium etli
casA encoding a secreted
calmodulin-related protein Chuanwu Xi, Eric Schoeters, Jos Vanderleyden, and Jan Michiels PMCID: PMC27157 Psychology From the Cover:
Reactivation of encoding-related brain activity during
memory retrieval Lars Nyberg, Reza Habib, Anthony R. McIntosh, and Endel Tulving PMCID: PMC27158 Memory's echo: Vivid remembering reactivates
sensory-specific cortex Mark E. Wheeler, Steven E. Petersen, and Randy L. Buckner PMCID: PMC27159 Social Sciences Anthropology From the Cover:
Soft-tissue characters in higher primate phylogenetics Sally Gibbs, Mark Collard, and Bernard Wood PMCID: PMC27160 Correction Proc Natl Acad Sci U S A. 2000 September 26; 97(20): 11133. Published online 2000 September 19. PMCID: PMC56101 Corrects: Yoshio Yamaoka, et al. A Mr 34,000 proinflammatory outer membrane protein (oipA) of Helicobacter pylori. Proc Natl Acad Sci U S A. 2000 June 20; 97(13): 7533–7538. |
