pmc logo imageJournal ListSearchpmc logo image
Logo of pnasPNAS Home page.PNAS Editorial BoardPNAS AboutPNAS SubscriptionsPNAS Info for Authors
This journal provides immediate access to some articles.
Other Issues:  previous | next | latest | archive
Volume 100(19);  September 16, 2003
Commentaries
Blocking the docking of HIV-1
Áine McKnight and Robin A. Weiss
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10581–10582. Published online 2003 September 8. doi: 10.1073/pnas.2035071100.
PMCID: PMC196843
Two distinct roles for terminal uridylyl transferases in RNA editing
Jonatha M. Gott
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10583–10584. Published online 2003 September 8. doi: 10.1073/pnas.2035062100.
PMCID: PMC196844
From the Cover:
Extending the utility of gene profiling data by bridging microarray platforms
Gregory Z. Ferl, John M. Timmerman, and Owen N. Witte
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10585–10587. Published online 2003 September 8. doi: 10.1073/pnas.2034937100.
PMCID: PMC196845
Endothelin-1 and osteoblastic metastasis
Gregory R. Mundy
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10588–10589. Published online 2003 September 8. doi: 10.1073/pnas.2035063100.
PMCID: PMC196846
Innovations in the design of bundled-item auctions
Charles Noussair
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10590–10591. Published online 2003 September 8. doi: 10.1073/pnas.1934705100.
PMCID: PMC196847
Perspective
The Trojan exosome hypothesis
Stephen J. Gould, Amy M. Booth, and James E. K. Hildreth
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10592–10597. Published online 2003 August 28. doi: 10.1073/pnas.1831413100.
PMCID: PMC196848
The entry of entry inhibitors: A fusion of science and medicine
John P. Moore and Robert W. Doms
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10598–10602. Published online 2003 September 5. doi: 10.1073/pnas.1932511100.
PMCID: PMC196849
Physical Sciences
Applied Mathematics
Combinatorial auction design
David Porter, Stephen Rassenti, Anil Roopnarine, and Vernon Smith
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11153–11157. Published online 2003 July 31. doi: 10.1073/pnas.1633736100.
PMCID: PMC196943
Applied Physical Sciences
From micro to nano contacts in biological attachment devices
Eduard Arzt, Stanislav Gorb, and Ralph Spolenak
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10603–10606. Published online 2003 September 5. doi: 10.1073/pnas.1534701100.
PMCID: PMC196850
Smart dust: Self-assembling, self-orienting photonic crystals of porous Si
Jamie R. Link and Michael J. Sailor
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10607–10610. Published online 2003 August 28. doi: 10.1073/pnas.1233824100.
PMCID: PMC196851
Chemistry
Evidence for an enantioselective pumiliotoxin 7-hydroxylase in dendrobatid poison frogs of the genus Dendrobates
John W. Daly, H. Martin Garraffo, Thomas F. Spande, Valerie C. Clark, Jingyuan Ma, Herman Ziffer, and John F. Cover, Jr.
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11092–11097. Published online 2003 September 5. doi: 10.1073/pnas.1834430100.
PMCID: PMC196932
Biological Sciences
Applied Biological Sciences
Polydispersity of a mammalian chaperone: Mass spectrometry reveals the population of oligomers in αB-crystallin
J. Andrew Aquilina, Justin L. P. Benesch, Orval A. Bateman, Christine Slingsby, and Carol V. Robinson
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10611–10616. Published online 2003 August 28. doi: 10.1073/pnas.1932958100.
PMCID: PMC196852
Biochemistry
From the Cover:
A tale of two TUTases
Ruslan Aphasizhev, Inna Aphasizheva, and Larry Simpson
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10617–10622. Published online 2003 September 3. doi: 10.1073/pnas.1833120100.
PMCID: PMC196853
Endothelial cell diversity revealed by global expression profiling
Jen-Tsan Chi, Howard Y. Chang, Guttorm Haraldsen, Frode L. Jahnsen, Olga G. Troyanskaya, Dustin S. Chang, Zhen Wang, Stanley G. Rockson, Matt van de Rijn, David Botstein, and Patrick O. Brown
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10623–10628. Published online 2003 September 8. doi: 10.1073/pnas.1434429100.
PMCID: PMC196854
Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187
Scott Classen, Stephane Olland, and James M. Berger
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10629–10634. Published online 2003 September 8. doi: 10.1073/pnas.1832879100.
PMCID: PMC196855
The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies
Yutong Xue, Richard Gibbons, Zhijiang Yan, Dafeng Yang, Tarra L. McDowell, Salvatore Sechi, Jun Qin, Sharleen Zhou, Doug Higgs, and Weidong Wang
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10635–10640. Published online 2003 September 2. doi: 10.1073/pnas.1937626100.
PMCID: PMC196856
(+)-Larreatricin hydroxylase, an enantio-specific polyphenol oxidase from the creosote bush (Larrea tridentata)
Man-Ho Cho, Syed G. A. Moinuddin, Gregory L. Helms, Shojiro Hishiyama, Dietmar Eichinger, Laurence B. Davin, and Norman G. Lewis
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10641–10646. Published online 2003 September 5. doi: 10.1073/pnas.1934562100.
PMCID: PMC196857
Cholesterol-induced conformational change in SCAP enhanced by Insig proteins and mimicked by cationic amphiphiles
Christopher M. Adams, Joseph L. Goldstein, and Michael S. Brown
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10647–10652. Published online 2003 September 8. doi: 10.1073/pnas.1534833100.
PMCID: PMC196858
Nitric oxide inhibits H2O2-induced transferrin receptor-dependent apoptosis in endothelial cells: Role of ubiquitin-proteasome pathway
Srigiridhar Kotamraju, Yoshiko Tampo, Agnes Keszler, Christopher R. Chitambar, Joy Joseph, Arthur L. Haas, and B. Kalyanaraman
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10653–10658. Published online 2003 September 4. doi: 10.1073/pnas.1933581100.
PMCID: PMC196859
De novo synthesis of bacterial glycogen: Agrobacterium tumefaciens glycogen synthase is involved in glucan initiation and elongation
Juan E. Ugalde, Armando J. Parodi, and Rodolfo A. Ugalde
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10659–10663. Published online 2003 September 5. doi: 10.1073/pnas.1534787100.
PMCID: PMC196860
VEGF induces S1P1 receptors in endothelial cells: Implications for cross-talk between sphingolipid and growth factor receptors
Junsuke Igarashi, Phillip A. Erwin, Ana Paula V. Dantas, Hongjie Chen, and Thomas Michel
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10664–10669. Published online 2003 September 8. doi: 10.1073/pnas.1934494100.
PMCID: PMC196861
Age-dependent deficiency in import of mitochondrial DNA glycosylases required for repair of oxidatively damaged bases
Bartosz Szczesny, Tapas K. Hazra, John Papaconstantinou, Sankar Mitra, and Istvan Boldogh
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10670–10675. Published online 2003 September 5. doi: 10.1073/pnas.1932854100.
PMCID: PMC196862
Calcium regulation of the soluble adenylyl cyclase expressed in mammalian spermatozoa
Bijay S. Jaiswal and Marco Conti
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10676–10681. Published online 2003 September 4. doi: 10.1073/pnas.1831008100.
PMCID: PMC196863
GPI transamidase of Trypanosoma brucei has two previously uncharacterized (trypanosomatid transamidase 1 and 2) and three common subunits
Kisaburo Nagamune, Kazuhito Ohishi, Hisashi Ashida, Yeonchul Hong, Jun Hino, Kenji Kangawa, Norimitsu Inoue, Yusuke Maeda, and Taroh Kinoshita
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10682–10687. Published online 2003 September 4. doi: 10.1073/pnas.1833260100.
PMCID: PMC196864
Differential substrate-induced signaling through the TonB-dependent transporter BtuB
Nathalie Cadieux, Phu G. Phan, David S. Cafiso, and Robert J. Kadner
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10688–10693. Published online 2003 September 4. doi: 10.1073/pnas.1932538100.
PMCID: PMC196865
The first external loop of the metal ion transporter DCT1 is involved in metal ion binding and specificity
Adiel Cohen, Yaniv Nevo, and Nathan Nelson
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10694–10699. Published online 2003 September 3. doi: 10.1073/pnas.1934572100.
PMCID: PMC196866
Biophysics
Funnel sculpting for in silico assembly of secondary structure elements of proteins
Boris Fain and Michael Levitt
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10700–10705. Published online 2003 August 18. doi: 10.1073/pnas.1732312100.
PMCID: PMC293046
The conformation of neurotensin bound to its G protein-coupled receptor
Sorin Luca, Jim F. White, Awinder K. Sohal, Dmitri V. Filippov, Jacques H. van Boom, Reinhard Grisshammer, and Marc Baldus
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10706–10711. Published online 2003 September 5. doi: 10.1073/pnas.1834523100.
PMCID: PMC196868
Coarse-grained sequences for protein folding and design
Scott Brown, Nicolas J. Fawzi, and Teresa Head-Gordon
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10712–10717. Published online 2003 September 8. doi: 10.1073/pnas.1931882100.
PMCID: PMC196869
Engineering asymmetric vesicles
Sophie Pautot, Barbara J. Frisken, and D. A. Weitz
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10718–10721. Published online 2003 September 8. doi: 10.1073/pnas.1931005100.
PMCID: PMC196870
Brain imaging in awake infants by near-infrared optical topography
Gentaro Taga, Kayo Asakawa, Atsushi Maki, Yukuo Konishi, and Hideaki Koizumi
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10722–10727. Published online 2003 September 5. doi: 10.1073/pnas.1932552100.
PMCID: PMC196871
Ionizing radiation induces heritable disruption of epithelial cell interactions
Catherine C. Park, Rhonda L. Henshall-Powell, Anna C. Erickson, Rabih Talhouk, Bahram Parvin, Mina J. Bissell, and Mary Helen Barcellos-Hoff
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10728–10733. Published online 2003 September 5. doi: 10.1073/pnas.1832185100.
PMCID: PMC196872
The role of certain Post classes in Boolean network models of genetic networks
Ilya Shmulevich, Harri Lähdesmäki, Edward R. Dougherty, Jaakko Astola, and Wei Zhang
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10734–10739. Published online 2003 September 8. doi: 10.1073/pnas.1534782100.
PMCID: PMC202352
Cell Biology
Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration
M. Okigaki, C. Davis, M. Falasca, S. Harroch, D. P. Felsenfeld, M. P. Sheetz, and J. Schlessinger
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10740–10745. Published online 2003 September 5. doi: 10.1073/pnas.1834348100.
PMCID: PMC196873
Role of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferase
Kiran N. Mahajan and Beverly S. Mitchell
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10746–10751. Published online 2003 September 5. doi: 10.1073/pnas.1631060100.
PMCID: PMC196874
Nuclear actin and protein 4.1: Essential interactions during nuclear assembly in vitro
Sharon Wald Krauss, Cynthia Chen, Sheldon Penman, and Rebecca Heald
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10752–10757. Published online 2003 September 5. doi: 10.1073/pnas.1934680100.
PMCID: PMC196875
Intra-G1 arrest in response to UV irradiation in fission yeast
Esben A. Nilssen, Marianne Synnes, Nancy Kleckner, Beáta Grallert, and Erik Boye
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10758–10763. Published online 2003 September 5. doi: 10.1073/pnas.1833769100.
PMCID: PMC196876
A quantitative characterization of the yeast heterotrimeric G protein cycle
Tau-Mu Yi, Hiroaki Kitano, and Melvin I. Simon
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10764–10769. Published online 2003 September 5. doi: 10.1073/pnas.1834247100.
PMCID: PMC196877
Transcription factor JunD, deprived of menin, switches from growth suppressor to growth promoter
Sunita K. Agarwal, Elizabeth A. Novotny, Judy S. Crabtree, Jonathan B. Weitzman, Moshe Yaniv, A. Lee Burns, Settara C. Chandrasekharappa, Francis S. Collins, Allen M. Spiegel, and Stephen J. Marx
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10770–10775. Published online 2003 September 5. doi: 10.1073/pnas.1834524100.
PMCID: PMC196878
The PDZ-binding motif of the β2-adrenoceptor is essential for physiologic signaling and trafficking in cardiac myocytes
Yang Xiang and Brian Kobilka
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10776–10781. Published online 2003 September 3. doi: 10.1073/pnas.1831718100.
PMCID: PMC196879
Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
Huijun Wei, Seungkirl Ahn, Sudha K. Shenoy, Sadashiva S. Karnik, László Hunyady, Louis M. Luttrell, and Robert J. Lefkowitz
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10782–10787. Published online 2003 August 29. doi: 10.1073/pnas.1834556100.
PMCID: PMC196880
Rho-dependent formation of epithelial “leader” cells during wound healing
T. Omelchenko, J. M. Vasiliev, I. M. Gelfand, H. H. Feder, and E. M. Bonder
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10788–10793. Published online 2003 September 5. doi: 10.1073/pnas.1834401100.
PMCID: PMC196881
Developmental Biology
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
Hwei-Ling Cheng, Raul Mostoslavsky, Shin'ichi Saito, John P. Manis, Yansong Gu, Parin Patel, Roderick Bronson, Ettore Appella, Frederick W. Alt, and Katrin F. Chua
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10794–10799. Published online 2003 September 5. doi: 10.1073/pnas.1934713100.
PMCID: PMC196882
Ecology
Sporormiella and the late Holocene extinctions in Madagascar
David A. Burney, Guy S. Robinson, and Lida Pigott Burney
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10800–10805. Published online 2003 September 5. doi: 10.1073/pnas.1534700100.
PMCID: PMC196883
Evolution
From micro to nano contacts in biological attachment devices
Eduard Arzt, Stanislav Gorb, and Ralph Spolenak
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10603–10606. Published online 2003 September 5. doi: 10.1073/pnas.1534701100.
PMCID: PMC196850
Active self-splicing group I introns in 23S rRNA genes of hyperthermophilic bacteria, derived from introns in eukaryotic organelles
Camilla L. Nesbø and W. Ford Doolittle
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10806–10811. Published online 2003 August 28. doi: 10.1073/pnas.1434268100.
PMCID: PMC196884
Distinct geographic patterns of genetic diversity are maintained in wild barley (Hordeum vulgare ssp. spontaneum) despite migration
Peter L. Morrell, Karen E. Lundy, and Michael T. Clegg
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10812–10817. Published online 2003 September 8. doi: 10.1073/pnas.1633708100.
PMCID: PMC196885
Semipermeable species boundaries between Anopheles gambiae and Anopheles arabiensis: Evidence from multilocus DNA sequence variation
N. J. Besansky, J. Krzywinski, T. Lehmann, F. Simard, M. Kern, O. Mukabayire, D. Fontenille, Y. Touré, and N'F. Sagnon
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10818–10823. Published online 2003 August 28. doi: 10.1073/pnas.1434337100.
PMCID: PMC196886
Horizontal gene transfer from flowering plants to Gnetum
Hyosig Won and Susanne S. Renner
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10824–10829. Published online 2003 September 8. doi: 10.1073/pnas.1833775100.
PMCID: PMC196887
Resistance of virus to extinction on bottleneck passages: Study of a decaying and fluctuating pattern of fitness loss
Ester Lázaro, Cristina Escarmís, Juan Pérez-Mercader, Susanna C. Manrubia, and Esteban Domingo
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10830–10835. Published online 2003 September 5. doi: 10.1073/pnas.1332668100.
PMCID: PMC196888
Synteny perturbations between wheat homoeologous chromosomes caused by locus duplications and deletions correlate with recombination rates
Eduard D. Akhunov, Alina R. Akhunova, Anna M. Linkiewicz, Jorge Dubcovsky, David Hummel, Gerry Lazo, Shiaoman Chao, Olin D. Anderson, Jacques David, Lili Qi, Benjamin Echalier, Bikram S. Gill, Miftahudin, J. Perry Gustafson, Mauricio La Rota, Mark E. Sorrells, Deshui Zhang, Henry T. Nguyen, Venugopal Kalavacharla, Khwaja Hossain, Shahryar F. Kianian, Junhua Peng, Nora L. V. Lapitan, Emily J. Wennerlind, Vivienne Nduati, James A. Anderson, Deepak Sidhu, Kulvinder S. Gill, Patrick E. McGuire, Calvin O. Qualset, and Jan Dvorak
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10836–10841. Published online 2003 September 5. doi: 10.1073/pnas.1934431100.
PMCID: PMC196889
Genetics
Local Context Finder (LCF) reveals multidimensional relationships among mRNA expression profiles of Arabidopsis responding to pathogen infection
Fumiaki Katagiri and Jane Glazebrook
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10842–10847. Published online 2003 September 5. doi: 10.1073/pnas.1934349100.
PMCID: PMC196890
Specificity in the activation and control of transcription factor E2F-dependent apoptosis
Timothy C. Hallstrom and Joseph R. Nevins
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10848–10853. Published online 2003 September 3. doi: 10.1073/pnas.1831408100.
PMCID: PMC196891
Genetic regulation of telomere-telomere fusions in the yeast Saccharomyces cerevisae
Piotr A. Mieczkowski, Joanna O. Mieczkowska, Margaret Dominska, and Thomas D. Petes
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10854–10859. Published online 2003 September 8. doi: 10.1073/pnas.1934561100.
PMCID: PMC196892
Mapping Drosophila mutations with molecularly defined P element insertions
R. Grace Zhai, P. Robin Hiesinger, Tong-Wey Koh, Patrik Verstreken, Karen L. Schulze, Yu Cao, Hamed Jafar-Nejad, Koenraad K. Norga, Hongling Pan, Vafa Bayat, Michael P. Greenbaum, and Hugo J. Bellen
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10860–10865. Published online 2003 September 5. doi: 10.1073/pnas.1832753100.
PMCID: PMC196893
Wnt4 overexpression disrupts normal testicular vasculature and inhibits testosterone synthesis by repressing steroidogenic factor 1/β-catenin synergy
Brian K. Jordan, Jennifer H.-C. Shen, Robert Olaso, Holly A. Ingraham, and Eric Vilain
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10866–10871. Published online 2003 August 29. doi: 10.1073/pnas.1834480100.
PMCID: PMC196894
Immunology
Selective contribution of IFN-α/β signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection
Kenya Honda, Shinya Sakaguchi, Chigusa Nakajima, Ai Watanabe, Hideyuki Yanai, Misako Matsumoto, Toshiaki Ohteki, Tsuneyasu Kaisho, Akinori Takaoka, Shizuo Akira, Tsukasa Seya, and Tadatsugu Taniguchi
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10872–10877. Published online 2003 September 5. doi: 10.1073/pnas.1934678100.
PMCID: PMC196895
CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-β–TGF-β receptor interactions in type 1 diabetes
E. Allison Green, Leonid Gorelik, Catrin M. McGregor, Elise H. Tran, and Richard A. Flavell
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10878–10883. Published online 2003 August 29. doi: 10.1073/pnas.1834400100.
PMCID: PMC196896
Diversity of core antigen epitopes of hepatitis B virus
D. M. Belnap, N. R. Watts, J. F. Conway, N. Cheng, S. J. Stahl, P. T. Wingfield, and A. C. Steven
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10884–10889. Published online 2003 September 3. doi: 10.1073/pnas.1834404100.
PMCID: PMC196897
Temporal activation of NF-κB regulates an interferon-independent innate antiviral response against cytoplasmic RNA viruses
Santanu Bose, Niladri Kar, Ratan Maitra, Joseph A. DiDonato, and Amiya K. Banerjee
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10890–10895. Published online 2003 September 5. doi: 10.1073/pnas.1832775100.
PMCID: PMC196898
HLA-E-restricted recognition of cytomegalovirus-derived peptides by human CD8+ cytolytic T lymphocytes
Gabriella Pietra, Chiara Romagnani, Paola Mazzarino, Michela Falco, Enrico Millo, Alessandro Moretta, Lorenzo Moretta, and Maria Cristina Mingari
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10896–10901. Published online 2003 September 5. doi: 10.1073/pnas.1834449100.
PMCID: PMC196899
CD4+ CD25+ T cells responding to serologically defined autoantigens suppress antitumor immune responses
Hiroyoshi Nishikawa, Takuma Kato, Koji Tanida, Atsunori Hiasa, Isao Tawara, Hiroaki Ikeda, Yoshinori Ikarashi, Hiro Wakasugi, Mitchell Kronenberg, Toshinori Nakayama, Masaru Taniguchi, Kagemasa Kuribayashi, Lloyd J. Old, and Hiroshi Shiku
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10902–10906. Published online 2003 August 28. doi: 10.1073/pnas.1834479100.
PMCID: PMC196900
Rapid induction of medullary thymocyte phenotypic maturation and egress inhibition by nanomolar sphingosine 1-phosphate receptor agonist
Hugh Rosen, Christopher Alfonso, Charles D. Surh, and Michael G. McHeyzer-Williams
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10907–10912. Published online 2003 September 3. doi: 10.1073/pnas.1832725100.
PMCID: PMC196901
The response of natural killer T cells to glycolipid antigens is characterized by surface receptor down-modulation and expansion
Michael T. Wilson, Cecilia Johansson, Danyvid Olivares-Villagómez, Avneesh K. Singh, Aleksandar K. Stanic, Chyung-Ru Wang, Sebastian Joyce, Mary Jo Wick, and Luc Van Kaer
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10913–10918. Published online 2003 September 5. doi: 10.1073/pnas.1833166100.
PMCID: PMC196902
Antigen-driven T cell anergy and defective memory T cell response via deregulated Rap1 activation in SPA-1-deficient mice
Daisuke Ishida, Hailin Yang, Kyoko Masuda, Kanami Uesugi, Hiroshi Kawamoto, Masakazu Hattori, and Nagahiro Minato
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10919–10924. Published online 2003 September 4. doi: 10.1073/pnas.1834525100.
PMCID: PMC196903
A dually active anthrax vaccine that confers protection against both bacilli and toxins
Gi-Eun Rhie, Michael H. Roehrl, Michael Mourez, R. John Collier, John J. Mekalanos, and Julia Y. Wang
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10925–10930. Published online 2003 September 5. doi: 10.1073/pnas.1834478100.
PMCID: PMC196904
Medical Sciences
Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187
Scott Classen, Stephane Olland, and James M. Berger
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10629–10634. Published online 2003 September 8. doi: 10.1073/pnas.1832879100.
PMCID: PMC196855
A neural survival factor is a candidate oncogene in breast cancer
Dale Porter, Stanislawa Weremowicz, Koei Chin, Pankaj Seth, Aparna Keshaviah, Jaana Lahti-Domenici, Young Kyung Bae, Constance L. Monitto, Ana Merlos-Suarez, Jennifer Chan, Christine M. Hulette, Andrea Richardson, Cynthia C. Morton, Jeffrey Marks, Mabel Duyao, Ralph Hruban, Edward Gabrielson, Rebecca Gelman, and Kornelia Polyak
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10931–10936. Published online 2003 September 2. doi: 10.1073/pnas.1932980100.
PMCID: PMC196905
Interaction of a selective cyclooxygenase-2 inhibitor with aspirin and NO-releasing aspirin in the human gastric mucosa
Stefano Fiorucci, Luca Santucci, John L. Wallace, Marco Sardina, Mario Romano, Piero del Soldato, and Antonio Morelli
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10937–10941. Published online 2003 September 5. doi: 10.1073/pnas.1933204100.
PMCID: PMC196906
Ionizing radiation delivered by specific antibody is therapeutic against a fungal infection
Ekaterina Dadachova, Antonio Nakouzi, Ruth A. Bryan, and Arturo Casadevall
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10942–10947. Published online 2003 August 20. doi: 10.1073/pnas.1731272100.
PMCID: PMC196907
From the Cover:
Bacterial pathogens modulate an apoptosis differentiation program in human neutrophils
Scott D. Kobayashi, Kevin R. Braughton, Adeline R. Whitney, Jovanka M. Voyich, Tom G. Schwan, James M. Musser, and Frank R. DeLeo
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10948–10953. Published online 2003 September 5. doi: 10.1073/pnas.1833375100.
PMCID: PMC196908
From the Cover:
A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases
Juan Juan Yin, Khalid S. Mohammad, Sanna M. Käkönen, Stephen Harris, J. Ruth Wu-Wong, Jerry L. Wessale, Robert J. Padley, I. Ross Garrett, John M. Chirgwin, and Theresa A. Guise
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10954–10959. Published online 2003 August 26. doi: 10.1073/pnas.1830978100.
PMCID: PMC196909
Repeated challenge with prion disease: The risk of infection and impact on incubation period
Mike B. Gravenor, Nigel Stallard, Robert Curnow, and Angela R. McLean
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10960–10965. Published online 2003 September 5. doi: 10.1073/pnas.1833677100.
PMCID: PMC198321
Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice
Faith M. Harris, Walter J. Brecht, Qin Xu, Ina Tesseur, Lisa Kekonius, Tony Wyss-Coray, Jo Dee Fish, Eliezer Masliah, Paul C. Hopkins, Kimberly Scearce-Levie, Karl H. Weisgraber, Lennart Mucke, Robert W. Mahley, and Yadong Huang
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10966–10971. Published online 2003 August 25. doi: 10.1073/pnas.1434398100.
PMCID: PMC196910
Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54
Nicolas de Roux, Emmanuelle Genin, Jean-Claude Carel, Fumihiko Matsuda, Jean-Louis Chaussain, and Edwin Milgrom
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10972–10976. Published online 2003 August 27. doi: 10.1073/pnas.1834399100.
PMCID: PMC196911
CD8+ T cell-mediated CXC chemokine receptor 4-simian/human immunodeficiency virus suppression in dually infected rhesus macaques
Janet M. Harouse, Clarisa Buckner, Agegnehu Gettie, Ross Fuller, Rudolf Bohm, James Blanchard, and Cecilia Cheng-Mayer
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10977–10982. Published online 2003 September 8. doi: 10.1073/pnas.1933268100.
PMCID: PMC196912
Microbiology
Genetic identification of a respiratory arsenate reductase
Chad W. Saltikov and Dianne K. Newman
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10983–10988. Published online 2003 August 25. doi: 10.1073/pnas.1834303100.
PMCID: PMC196913
The EBV nuclear antigen 1 (EBNA1) enhances B cell immortalization several thousandfold
Sibille Humme, Gilbert Reisbach, Regina Feederle, Henri-Jacques Delecluse, Kristine Bousset, Wolfgang Hammerschmidt, and Aloys Schepers
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10989–10994. Published online 2003 August 28. doi: 10.1073/pnas.1832776100.
PMCID: PMC196914
Biofilm dispersal in Xanthomonas campestris is controlled by cell–cell signaling and is required for full virulence to plants
J. Maxwell Dow, Lisa Crossman, Kim Findlay, Yong-Qiang He, Jia-Xun Feng, and Ji-Liang Tang
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 10995–11000. Published online 2003 September 5. doi: 10.1073/pnas.1833360100.
PMCID: PMC196915
The response regulator Rrp2 is essential for the expression of major membrane lipoproteins in Borrelia burgdorferi
Xiaofeng F. Yang, Sophie M. Alani, and Michael V. Norgard
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11001–11006. Published online 2003 August 29. doi: 10.1073/pnas.1834315100.
PMCID: PMC196916
Phagocytosis by neutrophils induces an amino acid deprivation response in Saccharomyces cerevisiae and Candida albicans
Ifat Rubin-Bejerano, Iain Fraser, Paula Grisafi, and Gerald R. Fink
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11007–11012. Published online 2003 September 4. doi: 10.1073/pnas.1834481100.
PMCID: PMC196917
From the Cover:
A small molecule HIV-1 inhibitor that targets the HIV-1 envelope and inhibits CD4 receptor binding
Pin-Fang Lin, Wade Blair, Tao Wang, Timothy Spicer, Qi Guo, Nannan Zhou, Yi-Fei Gong, H.-G. Heidi Wang, Ronald Rose, Gregory Yamanaka, Brett Robinson, Chang-Ben Li, Robert Fridell, Carol Deminie, Gwendeline Demers, Zheng Yang, Lisa Zadjura, Nicholas Meanwell, and Richard Colonno
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11013–11018. Published online 2003 August 20. doi: 10.1073/pnas.1832214100.
PMCID: PMC196918
Neuroscience
Genetic contributions to generalized arousal of brain and behavior
J. Garey, A. Goodwillie, J. Frohlich, M. Morgan, J.-A. Gustafsson, O. Smithies, K. S. Korach, S. Ogawa, and D. W. Pfaff
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11019–11022. Published online 2003 August 20. doi: 10.1073/pnas.1633773100.
PMCID: PMC196919
Dynamic inhibition of excitatory synaptic transmission by astrocyte-derived ATP in hippocampal cultures
Schuichi Koizumi, Kayoko Fujishita, Makoto Tsuda, Yukari Shigemoto-Mogami, and Kazuhide Inoue
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11023–11028. Published online 2003 September 4. doi: 10.1073/pnas.1834448100.
PMCID: PMC196920
Odor maps of aldehydes and esters revealed by functional MRI in the glomerular layer of the mouse olfactory bulb
Fuqiang Xu, Nian Liu, Ikuhiro Kida, Douglas L. Rothman, Fahmeed Hyder, and Gordon M. Shepherd
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11029–11034. Published online 2003 September 8. doi: 10.1073/pnas.1832864100.
PMCID: PMC196921
Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons
Michel Cyr, Jean-Martin Beaulieu, Aki Laakso, Tatyana D. Sotnikova, Wei-Dong Yao, Laura M. Bohn, Raul R. Gainetdinov, and Marc G. Caron
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11035–11040. Published online 2003 September 4. doi: 10.1073/pnas.1831768100.
PMCID: PMC196922
Chronic, multisite, multielectrode recordings in macaque monkeys
Miguel A. L. Nicolelis, Dragan Dimitrov, Jose M. Carmena, Roy Crist, Gary Lehew, Jerald D. Kralik, and Steven P. Wise
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11041–11046. Published online 2003 September 5. doi: 10.1073/pnas.1934665100.
PMCID: PMC196923
GABA-enhanced collective behavior in neuronal axons underlies persistent gamma-frequency oscillations
R. D. Traub, M. O. Cunningham, T. Gloveli, F. E. N. LeBeau, A. Bibbig, E. H. Buhl, and M. A. Whittington
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11047–11052. Published online 2003 September 5. doi: 10.1073/pnas.1934854100.
PMCID: PMC196924
Electroencephalographic signatures of attentional and cognitive default modes in spontaneous brain activity fluctuations at rest
H. Laufs, K. Krakow, P. Sterzer, E. Eger, A. Beyerle, A. Salek-Haddadi, and A. Kleinschmidt
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11053–11058. Published online 2003 September 4. doi: 10.1073/pnas.1831638100.
PMCID: PMC196925
The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis
Craig S. Clements, Hugh H. Reid, Travis Beddoe, Fleur E. Tynan, Matthew A. Perugini, Terrance G. Johns, Claude C. A. Bernard, and Jamie Rossjohn
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11059–11064. Published online 2003 September 5. doi: 10.1073/pnas.1833158100.
PMCID: PMC196926
Trace amounts of copper in water induce β-amyloid plaques and learning deficits in a rabbit model of Alzheimer's disease
D. Larry Sparks and Bernard G. Schreurs
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11065–11069. Published online 2003 August 14. doi: 10.1073/pnas.1832769100.
PMCID: PMC196927
Reward-dependent plasticity in the primary auditory cortex of adult monkeys trained to discriminate temporally modulated signals
Ralph E. Beitel, Christoph E. Schreiner, Steven W. Cheung, Xiaoqin Wang, and Michael M. Merzenich
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11070–11075. Published online 2003 August 26. doi: 10.1073/pnas.1334187100.
PMCID: PMC196928
Coordination of central odor representations through transient, non-oscillatory synchronization of glomerular output neurons
Thomas A. Christensen, Hong Lei, and John G. Hildebrand
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11076–11081. Published online 2003 September 5. doi: 10.1073/pnas.1934001100.
PMCID: PMC196929
Neural image processing by dendritic networks
Hermann Cuntz, Jürgen Haag, and Alexander Borst
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11082–11085. Published online 2003 August 28. doi: 10.1073/pnas.1830705100.
PMCID: PMC196930
Pharmacology
Protean agonism at histamine H3 receptors in vitro and in vivo
Florence Gbahou, Agnès Rouleau, Séverine Morisset, Régis Parmentier, Sylvain Crochet, Jian-Sheng Lin, Xavier Ligneau, Joël Tardivel-Lacombe, Holger Stark, Walter Schunack, C. Robin Ganellin, Jean-Charles Schwartz, and Jean-Michel Arrang
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11086–11091. Published online 2003 September 5. doi: 10.1073/pnas.1932276100.
PMCID: PMC196931
Evidence for an enantioselective pumiliotoxin 7-hydroxylase in dendrobatid poison frogs of the genus Dendrobates
John W. Daly, H. Martin Garraffo, Thomas F. Spande, Valerie C. Clark, Jingyuan Ma, Herman Ziffer, and John F. Cover, Jr.
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11092–11097. Published online 2003 September 5. doi: 10.1073/pnas.1834430100.
PMCID: PMC196932
Physiology
Correction of proximal tubule phosphate transport defect in Hyp mice in vivo and in vitro with indomethacin
Michel Baum, Samer Loleh, Neel Saini, Mouin Seikaly, Vangipuram Dwarakanath, and Raymond Quigley
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11098–11103. Published online 2003 September 2. doi: 10.1073/pnas.1834060100.
PMCID: PMC196933
Proteinase-activated receptor 1 activation induces epithelial apoptosis and increases intestinal permeability
Alex C. Chin, Nathalie Vergnolle, Wallace K. MacNaughton, John L. Wallace, Morley D. Hollenberg, and Andre G. Buret
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11104–11109. Published online 2003 September 5. doi: 10.1073/pnas.1831452100.
PMCID: PMC196934
Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle
Shaikh Mizanoor Rahman, Agnieszka Dobrzyn, Pawel Dobrzyn, Seong-Ho Lee, Makoto Miyazaki, and James M. Ntambi
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11110–11115. Published online 2003 September 5. doi: 10.1073/pnas.1934571100.
PMCID: PMC196935
Plant Biology
Nitric oxide regulates K+ and Cl- channels in guard cells through a subset of abscisic acid-evoked signaling pathways
Carlos Garcia-Mata, Robert Gay, Sergei Sokolovski, Adrian Hills, Lorenzo Lamattina, and Michael R. Blatt
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11116–11121. Published online 2003 August 29. doi: 10.1073/pnas.1434381100.
PMCID: PMC196936
The plant homolog to the human sodium/dicarboxylic cotransporter is the vacuolar malate carrier
Vera Emmerlich, Nicole Linka, Thomas Reinhold, Marco A. Hurth, Michaela Traub, Enrico Martinoia, and H. Ekkehard Neuhaus
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11122–11126. Published online 2003 August 28. doi: 10.1073/pnas.1832002100.
PMCID: PMC196937
Localization of a bacterial protein in starch granules of transgenic maize kernels
Rachel K. Chikwamba, M. Paul Scott, Lorena B. Mejía, Hugh S. Mason, and Kan Wang
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11127–11132. Published online 2003 September 5. doi: 10.1073/pnas.1836901100.
PMCID: PMC196938
Strand-biased DNA methylation associated with centromeric regions in Arabidopsis
Song Luo and Daphne Preuss
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11133–11138. Published online 2003 September 5. doi: 10.1073/pnas.1831011100.
PMCID: PMC196939
Population Biology
El Niño drives timing of breeding but not population growth in the song sparrow (Melospiza melodia)
Scott Wilson and Peter Arcese
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11139–11142. Published online 2003 September 5. doi: 10.1073/pnas.1931407100.
PMCID: PMC196940
Population dynamics of rapid fixation in cytotoxic T lymphocyte escape mutants of influenza A
Julia R. Gog, Guus F. Rimmelzwaan, Albert D. M. E. Osterhaus, and Bryan T. Grenfell
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11143–11147. Published online 2003 September 3. doi: 10.1073/pnas.1830296100.
PMCID: PMC196941
Psychology
Affective style and in vivo immune response: Neurobehavioral mechanisms
Melissa A. Rosenkranz, Daren C. Jackson, Kim M. Dalton, Isa Dolski, Carol D. Ryff, Burt H. Singer, Daniel Muller, Ned H. Kalin, and Richard J. Davidson
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11148–11152. Published online 2003 September 5. doi: 10.1073/pnas.1534743100.
PMCID: PMC196942
Social Sciences
Economic Sciences
Combinatorial auction design
David Porter, Stephen Rassenti, Anil Roopnarine, and Vernon Smith
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11153–11157. Published online 2003 July 31. doi: 10.1073/pnas.1633736100.
PMCID: PMC196943
Globalization and the distribution of income: The economic arguments
Ronald W. Jones
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11158–11162. Published online 2003 September 5. doi: 10.1073/pnas.1733335100.
PMCID: PMC196944
Psychology
Culture and point of view
Richard E. Nisbett and Takahiko Masuda
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11163–11170. Published online 2003 September 5. doi: 10.1073/pnas.1934527100.
PMCID: PMC196945
Dissociable neural mechanisms underlying response-based and familiarity-based conflict in working memory
James K. Nelson, Patricia A. Reuter-Lorenz, Ching-Yune C. Sylvester, John Jonides, and Edward E. Smith
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11171–11175. Published online 2003 September 4. doi: 10.1073/pnas.1334125100.
PMCID: PMC196946
Social Sciences
Explaining happiness
Richard A. Easterlin
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11176–11183. Published online 2003 September 4. doi: 10.1073/pnas.1633144100.
PMCID: PMC196947
Correction
Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11184. doi: 10.1073/pnas.1934557100.
PMCID: PMC196948
Corrects: Vikas K. Goel, et al. Band 3 is a host receptor binding merozoite surface protein 1 during the Plasmodium falciparum invasion of erythrocytes. Proc Natl Acad Sci U S A. 2003 April 29; 100(9): 5164–5169.
Other Issues:  previous | next | latest | archive