| | This journal provides immediate access to some articles. Commentaries The Alzheimer family of diseases: Many etiologies, one pathogenesis? John Hardy Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2095–2097. PMCID: PMC33655 Pax-6: Where to be conserved is not conservative William A. Harris Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2098–2100. PMCID: PMC33656 Bronchial asthma: Lessons from murine models G. J. Gleich and H. Kita Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2101–2102. PMCID: PMC33657 Altered DNA methylation and genome instability: A new pathway
to cancer? Peter A. Jones and Mark L. Gonzalgo Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2103–2105. PMCID: PMC33658 Perspective The objects of selection Ernst Mayr Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2091–2094. PMCID: PMC33654 Physical Sciences Chemistry Virtual combinatorial libraries: Dynamic generation of molecular and supramolecular diversity by self-assembly Ivan Huc and Jean-Marie Lehn Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2106–2110. PMCID: PMC20048 Biological Sciences Agricultural Sciences Transgenic elite indica rice plants expressing CryIAc -endotoxin of Bacillus thuringiensis are resistant against yellow stem borer ( Scirpophagaincertulas) Pritilata Nayak, Debabrata Basu, Sampa Das, Asitava Basu, Dipankar Ghosh, Neeliyath A. Ramakrishnan, Maloy Ghosh, and Soumitra K. Sen Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2111–2116. PMCID: PMC20049 Applied Biological Sciences Selection of marker-free transgenic plants using the isopentenyl transferase gene Hiroyasu Ebinuma, Koichi Sugita, Etsuko Matsunaga, and Mikiko Yamakado Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2117–2121. PMCID: PMC20050 Removal of a cryptic intron and subcellular localization of green fluorescent protein are required to mark transgenic Arabidopsis plants brightly Jim Haseloff, Kirby R. Siemering, Douglas C. Prasher, and Sarah Hodge Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2122–2127. PMCID: PMC20051 Generation of cDNA expression libraries enriched for in-frame sequences Claytus A. Davis and Seymour Benzer Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2128–2132. PMCID: PMC20052 Biochemistry Identification of a functional water channel in cytochrome P450 enzymes Tudor I. Oprea, Gerhard Hummer, and Angel E. García Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2133–2138. PMCID: PMC20053 Structural features of the binding site for ribosomal protein S8 in Escherichia coli 16S rRNA defined using NMR spectroscopy K. Kalurachchi, K. Uma, R. A. Zimmermann, and E. P. Nikonowicz Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2139–2144. PMCID: PMC20054 From phosphatases to vanadium peroxidases: A similar architecture of the active site Wieger Hemrika, Rokus Renirie, Henk L. Dekker, Phil Barnett, and Ron Wever Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2145–2149. PMCID: PMC20055 Discovery and analysis of inflammatory disease-related genes using cDNA microarrays Renu A. Heller, Mark Schena, Andrew Chai, Dari Shalon, Tod Bedilion, James Gilmore, David E. Woolley, and Ronald W. Davis Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2150–2155. PMCID: PMC20056 The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins Arnim Pause, Stephen Lee, Robert A. Worrell, David Y. T. Chen, Wilson H. Burgess, W. Marston Linehan, and Richard D. Klausner Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2156–2161. PMCID: PMC20057 Nucleoprotein-based nanoscale assembly Steven S. Smith, Luming Niu, David J. Baker, John A. Wendel, Susan E. Kane, and Darrin S. Joy Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2162–2167. PMCID: PMC20058 Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase Young-Guen Kwon, Soo Young Lee, Yongwon Choi, Paul Greengard, and Angus C. Nairn Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2168–2173. PMCID: PMC20059 Supercoil-induced extrusion of a regulatory DNA hairpin Xing Dai, Miriam B. Greizerstein, Krisztina Nadas-Chinni, and Lucia B. Rothman-Denes Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2174–2179. PMCID: PMC20060 Receptor and Gβγ isoform-specific interactions with G protein-coupled receptor kinases Yehia Daaka, Julie A. Pitcher, Mark Richardson, Robert H. Stoffel, Janet D. Robishaw, and Robert J. Lefkowitz Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2180–2185. PMCID: PMC20061 Silent information regulator protein complexes in Saccharomyces cerevisiae: A SIR2/SIR4 complex and evidence for a regulatory domain in SIR4 that inhibits its interaction with SIR3 Danesh Moazed, Amy Kistler, Amy Axelrod, Jasper Rine, and Alexander D. Johnson Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2186–2191. PMCID: PMC20062 Evidence for a lipochaperonin: Association of active proteinfolding GroESL oligomers with lipids can stabilize membranes under heat shock conditions Zsolt Török, Ibolya Horváth, Pierre Goloubinoff, Eszter Kovács, Attila Glatz, Gábor Balogh, and László Vígh Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2192–2197. PMCID: PMC20063 Identification of an alternative form of human lactoferrin mRNA that is expressed differentially in normal tissues and tumor-derived cell lines Paul D. Siebert and Betty C. B. Huang Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2198–2203. PMCID: PMC20064 A putative angiogenin receptor in angiogenin-responsive human endothelial cells Guo-fu Hu, James F. Riordan, and Bert L. Vallee Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2204–2209. PMCID: PMC20065 Volatile signals of the major histocompatibility complex in male mouse urine Alan G. Singer, Gary K. Beauchamp, and Kunio Yamazaki Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2210–2214. PMCID: PMC20066 DNA damage can alter the stability of nucleosomes: Effects are dependent on damage type David B. Mann, David L. Springer, and Michael J. Smerdon Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2215–2220. PMCID: PMC20067 Regulation of E2F through ubiquitin–proteasome-dependent degradation: Stabilization by the pRB tumor suppressor protein Miguel R. Campanero and Erik K. Flemington Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2221–2226. PMCID: PMC20068 Identification of a novel negative retinoic acid responsive element in the promoter of the human matrix Gla protein gene Jutta Kirfel, Manuela Kelter, Leonor M. Cancela, Paul A. Price, and Roland Schüle Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2227–2232. PMCID: PMC20069 Coordination dynamics of biological zinc “clusters” in metallothioneins and in the DNA-binding domain of the transcription factor Gal4 Wolfgang Maret, Kjeld S. Larsen, and Bert L. Vallee Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2233–2237. PMCID: PMC20070 Molecular characterization of human and mouse fatty acid amide hydrolases Dan K. Giang and Benjamin F. Cravatt Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2238–2242. PMCID: PMC20071 Sequence requirements of the HIV-1 protease flap region determined by saturation mutagenesis and kinetic analysis of flap mutants Wei Shao, Lorraine Everitt, Marianne Manchester, Daniel D. Loeb, Clyde A. Hutchison, III, and Ronald Swanstrom Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2243–2248. PMCID: PMC20072 The La antigen binds 5′ noncoding region of the hepatitis C virus RNA in the context of the initiator AUG codon and stimulates internal ribosome entry site-mediated translation Naushad Ali and Aleem Siddiqui Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2249–2254. PMCID: PMC20073 The biochemical basis for l-canavanine tolerance by the tobacco budworm Heliothis virescens(Noctuidae) Coromoto Melangeli, Gerald A. Rosenthal, and Douglas L. Dalman Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2255–2260. PMCID: PMC20074 Poly(ADP-ribose) polymerase enhances activator-dependent transcription invitroMichael Meisterernst, Gertraud Stelzer, and Robert G. Roeder Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2261–2265. PMCID: PMC20075 UV-induced mutagenesis of human p53 in a vector replicated in SaccharomycescerevisiaeDeborah J. Moshinsky and Gerald N. Wogan Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2266–2271. PMCID: PMC20076 Enhancer blocking activity located near the 3′ end of the sea urchin early H2A histone gene Franco Palla, Raffaella Melfi, Letizia Anello, Maria Di Bernardo, and Giovanni Spinelli Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2272–2277. PMCID: PMC20077 Coexpression of nuclear receptor partners increases their solubility and biological activities Chuan Li, John W. R. Schwabe, Ester Banayo, and Ronald M. Evans Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2278–2283. PMCID: PMC20078 Establishment of methylation-sensitive–representational difference analysis and isolation of hypo- and hypermethylated genomic fragments in mouse liver tumors Toshikazu Ushijima, Keiichirou Morimura, Yoko Hosoya, Hideo Okonogi, Masae Tatematsu, Takashi Sugimura, and Minako Nagao Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2284–2289. PMCID: PMC20079 Observations on catalysis by hammerhead ribozymes are consistent
with a two-divalent-metal-ion mechanism Brian W. Pontius, William B. Lott, and Peter H. von Hippel Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2290–2294. PMCID: PMC20080 Stat5 is a physiological substrate of the insulin receptor Jing Chen, Henry B. Sadowski, Ronald A. Kohanski, and Lu-Hai Wang Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2295–2300. PMCID: PMC20081 Biophysics Feedback inhibition of Ca 2+ channels by Ca 2+ depends on a short sequence of the C terminus that does not include the Ca 2+-binding function of a motif with similarity to Ca 2+-binding domains Jianming Zhou, Riccardo Olcese, Ning Qin, Francesca Noceti, Lutz Birnbaumer, and Enrico Stefani Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2301–2305. PMCID: PMC20082 Structural basis for dual excitation and photoisomerization of the Aequorea victoria green fluorescent protein Katjuša Brejc, Titia K. Sixma, Paul A. Kitts, Steven R. Kain, Roger Y. Tsien, Mats Ormö, and S. James Remington Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2306–2311. PMCID: PMC20083 Stepped versus continuous rotatory motors at the molecular scale Dirk Sabbert and Wolfgang Junge Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2312–2317. PMCID: PMC20084 An elementary mode coupling theory of random
heteropolymer dynamics Shoji Takada, John J. Portman, and Peter G. Wolynes Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2318–2321. PMCID: PMC20085 Single amino acid residue as a functional determinant of rod and cone visual pigments Hiroo Imai, Daisuke Kojima, Tomonori Oura, Shuji Tachibanaki, Akihisa Terakita, and Yoshinori Shichida Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2322–2326. PMCID: PMC20086 The structure of mitogen-activated protein kinase p38 at 2.1-Å resolution Zhulun Wang, Paul C. Harkins, Richard J. Ulevitch, Jiahuai Han, Melanie H. Cobb, and Elizabeth J. Goldsmith Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2327–2332. PMCID: PMC20087 Cell Biology COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform Kiyotoshi Kaneko, Martin Vey, Michael Scott, Susanne Pilkuhn, Fred E. Cohen, and Stanley B. Prusiner Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2333–2338. PMCID: PMC20088 Quantitative analysis of biological membrane lipids at the low picomole level by nano-electrospray ionization tandem mass spectrometry B. Brügger, G. Erben, R. Sandhoff, F. T. Wieland, and W. D. Lehmann Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2339–2344. PMCID: PMC20089 bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis Mila E. McCurrach, Thomas M. F. Connor, C. Michael Knudson, Stanley J. Korsmeyer, and Scott W. Lowe Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2345–2349. PMCID: PMC20090 Dissecting the thrombopoietin receptor: Functional elements of the Mpl cytoplasmic domain Jonathan G. Drachman and Kenneth Kaushansky Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2350–2355. PMCID: PMC20091 Downstream of Crk adaptor signaling pathway: Activation of Jun kinase by v-Crk through the guanine nucleotide exchange protein C3G Shinya Tanaka, Toru Ouchi, and Hidesaburo Hanafusa Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2356–2361. PMCID: PMC20092 Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase Fiona M. Townsley, Alexander Aristarkhov, Sharon Beck, Avram Hershko, and Joan V. Ruderman Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2362–2367. PMCID: PMC20093 Identification of the second cluster of ligand-binding repeats in megalin as a site for receptor–ligand interactions Robert A. Orlando, Markus Exner, Ralf-Peter Czekay, Hajime Yamazaki, Akihiko Saito, Robert Ullrich, Dontscho Kerjaschki, and Marilyn Gist Farquhar Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2368–2373. PMCID: PMC20094 cDNA cloning and expression of bovine procollagen I N-proteinase: A new member of the superfamily of zinc-metalloproteinases with binding sites for cells and other matrix components Alain Colige, Shi-Wu Li, Aleksander L. Sieron, Betty V. Nusgens, Darwin J. Prockop, and Charles M. Lapière Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2374–2379. PMCID: PMC20095 Aberrant trafficking of hepatitis B virus glycoproteins in cells in which N-glycan processing is inhibited Xuanyong Lu, Anand Mehta, Mitra Dadmarz, Raymond Dwek, Baruch S. Blumberg, and Timothy M. Block Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2380–2385. PMCID: PMC20096 Developmental Biology Expression of a dominant-negative type II transforming growth factor β (TGF-β) receptor in the epidermis of transgenic mice blocks TGF-β-mediated growth inhibition Xiao-Jing Wang, David A. Greenhalgh, Jackie R. Bickenbach, Aibo Jiang, Donnie S. Bundman, Thomas Krieg, Rik Derynck, and Dennis R. Roop Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2386–2391. PMCID: PMC20097 Function and regulation of heat shock factor 2 during mouse embryogenesis M. Rallu, Mt. Loones, Y. Lallemand, R. Morimoto, M. Morange, and V. Mezger Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2392–2397. PMCID: PMC20098 Molecular characterization of Br-cadherin, a developmentally regulated, brain-specific cadherin Sara Selig, Hart G. W. Lidov, Sandra A. Bruno, Michael M. Segal, and Louis M. Kunkel Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2398–2403. PMCID: PMC20099 Hedgehog signaling regulates transcription through cubitus interruptus, a sequence-specific DNA binding protein Tonia Von Ohlen, Derek Lessing, Roel Nusse, and Joan E. Hooper Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2404–2409. PMCID: PMC20100 Four highly stable eukaryotic mRNAs assemble 3′ untranslated region RNA–protein complexes sharing cis and trans components Martin Holcik and Stephen A. Liebhaber Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2410–2414. PMCID: PMC20101 Evolution Floral homeotic genes were recruited from homologous MADS-box genes preexisting in the common ancestor of ferns and seed plants Thomas Münster, Jens Pahnke, Alexandra Di Rosa, Jan T. Kim, William Martin, Heinz Saedler, and Günter Theissen Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2415–2420. PMCID: PMC20102 Squid Pax-6 and eye development Stanislav I. Tomarev, Patrick Callaerts, Lidia Kos, Rina Zinovieva, Georg Halder, Walter Gehring, and Joram Piatigorsky Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2421–2426. PMCID: PMC20103 Genetics Mutational studies of yeast transcription factor IIB in vivo reveal a functional surface important for gene activation Shruti P. Shaw, Daniel J. Carson, Michael J. Dorsey, and Jun Ma Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2427–2432. PMCID: PMC20104 egl-17 encodes an invertebrate fibroblast growth factor family member required specifically for sex myoblast migration in Caenorhabditiselegans Rebecca D. Burdine, Estella B. Chen, Shing F. Kwok, and Michael J. Stern Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2433–2437. PMCID: PMC20105 Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice Ryoko Araki, Akira Fujimori, Kiyohiro Hamatani, Kazuei Mita, Toshiyuki Saito, Masahiko Mori, Ryutaro Fukumura, Mitsuoki Morimyo, Masahiro Muto, Masahiro Itoh, Kouichi Tatsumi, and Masumi Abe Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2438–2443. PMCID: PMC20106 Binary transgenic mouse model for studying the trans control of globin gene switching: Evidence that GATA-1 is an in vivo repressor of human gene expression Qiliang Li, Christopher Clegg, Kenneth Peterson, Sara Shaw, Natacha Raich, and George Stamatoyannopoulos Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2444–2448. PMCID: PMC20107 Detection of heterozygous truncating mutations in the BRCA1 and APC genes by using a rapid screening assay in yeast Chikashi Ishioka, Takao Suzuki, Michael FitzGerald, Michael Krainer, Hideki Shimodaira, Akira Shimada, Tadashi Nomizu, Kurt J. Isselbacher, Daniel Haber, and Ryunosuke Kanamaru Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2449–2453. PMCID: PMC20108 Immunology Exploring the basis of peptide–carbohydrate crossreactivity: Evidence for discrimination by peptides between closely related anti-carbohydrate antibodies Shannon L. Harris, Lisa Craig, Jarnail S. Mehroke, Michael Rashed, Michael B. Zwick, Kelly Kenar, Eric J. Toone, Neil Greenspan, France-Isabelle Auzanneau, José-R. Marino-Albernas, B. Mario Pinto, and Jamie K. Scott Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2454–2459. PMCID: PMC20109 Lymphotoxin-β receptor signaling complex: Role of tumor necrosis factor receptor-associated factor 3 recruitment in cell death and activation of nuclear factor κB Todd L. VanArsdale, Sammee L. VanArsdale, Walker R. Force, Barbara N. Walter, George Mosialos, Elliott Kieff, John C. Reed, and Carl F. Ware Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2460–2465. PMCID: PMC20110 The pentamer channel stiffening model for drug action on human rhinovirus HRV-1A Nagarajan Vaidehi and William A. Goddard, III Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2466–2471. PMCID: PMC20111 Generation of NK1.1 + T cell antigen receptor α/β + thymocytes associated with intact thymic structure Ken-ichi Nakagawa, Kazuya Iwabuchi, Kazumasa Ogasawara, Manabu Ato, Masaharu Kajiwara, Hiroki Nishihori, Chikako Iwabuchi, Hiroshi Ishikura, Robert A. Good, and Kazunori Onoé Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2472–2477. PMCID: PMC20112 Impairment of antigen-specific antibody production in transgenic mice expressing a dominant-negative form of gp130 Atsushi Kumanogoh, Satoko Marukawa, Takayuki Kumanogoh, Hisao Hirota, Kenji Yoshida, Ihn-Sook Lee, Teruhito Yasui, Kanji Yoshida, Tetsuya Taga, and Tadamitsu Kishimoto Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2478–2482. PMCID: PMC20113 T cells cooperate with passive antibody to modify Cryptococcus neoformans infection in mice RuiRong Yuan, Arturo Casadevall, Jin Oh, and Matthew D. Scharff Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2483–2488. PMCID: PMC20114 Genetically engineered superantigens as tolerable antitumor agents Johan Hansson, Lennart Ohlsson, Robert Persson, Gunnar Andersson, Nils-Gunnar Ilbäck, Mark J. Litton, Terje Kalland, and Mikael Dohlsten Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2489–2494. PMCID: PMC20115 Stability of empty and peptide-loaded class II major histocompatibility complex molecules at neutral and endosomal pH: Comparison to class I proteins Ziv Reich, John D. Altman, J. Jay Boniface, Daniel S. Lyons, Haruo Kozono, Graham Ogg, Chantal Morgan, and Mark M. Davis Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2495–2500. PMCID: PMC20116 Importance of acidic, proline/serine/threonine-rich, and GTPbinding regions in the major histocompatibility complex class II transactivator: Generation of transdominant-negative mutants Keh-Chuang Chin, George G.-X. Li, and Jenny P.-Y. Ting Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2501–2506. PMCID: PMC20117 Fig1, an interleukin 4-induced mouse B cell gene isolated by cDNA representational difference analysis Charles C. Chu and William E. Paul Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2507–2512. PMCID: PMC20118 Pluripotent hemopoietic stem cells are c-kit <lowHiroshi Doi, Muneo Inaba, Yoshihisa Yamamoto, Shigeru Taketani, Shin-Ichiro Mori, Akira Sugihara, Hajime Ogata, Junko Toki, Hiroko Hisha, Kayo Inaba, Shinji Sogo, Masakazu Adachi, Tadashi Matsuda, Robert A. Good, and Susumu Ikehara Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2513–2517. PMCID: PMC20119 T cell receptor restriction of diabetogenic autoimmune NOD T cells E. Simone, D. Daniel, N. Schloot, P. Gottlieb, S. Babu, E. Kawasaki, D. Wegmann, and G. S. Eisenbarth Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2518–2521. PMCID: PMC20120 Medical Sciences Point mutations at the purine nucleoside phosphorylase locus impair thymocyte differentiation in the mouse Floyd F. Snyder, Jack P. Jenuth, Ellen R. Mably, and Rupinder K. Mangat Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2522–2527. PMCID: PMC20121 Prevention of experimental allergic encephalomyelitis by targeting nitric oxide and peroxynitrite: Implications for the treatment of multiple sclerosis D. Craig Hooper, Omar Bagasra, Joseph C. Marini, Anna Zborek, S. Tsuyoshi Ohnishi, Rhonda Kean, Jean M. Champion, Ashit B. Sarker, Lisa Bobroski, John L. Farber, Takaaki Akaike, Hiroshi Maeda, and Hilary Koprowski Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2528–2533. PMCID: PMC20122 Immunohistochemistry of HLA-H, the protein defective in patients with hereditary hemochromatosis, reveals unique pattern of expression in gastrointestinal tract Seppo Parkkila, Abdul Waheed, Robert S. Britton, John N. Feder, Zenta Tsuchihashi, Randall C. Schatzman, Bruce R. Bacon, and William S. Sly Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2534–2539. PMCID: PMC20123 α-Galactosidase A deficient mice: A model of Fabry disease Toshio Ohshima, Gary J. Murray, William D. Swaim, Glenn Longenecker, Jane M. Quirk, Carol O. Cardarelli, Yoshikazu Sugimoto, Ira Pastan, Michael M. Gottesman, Roscoe O. Brady, and Ashok B. Kulkarni Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2540–2544. PMCID: PMC20124 DNA methylation and genetic instability in colorectal cancer cells Christoph Lengauer, Kenneth W. Kinzler, and Bert Vogelstein Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2545–2550. PMCID: PMC20125 A PMLRARα transgene initiates murine acute promyelocytic leukemia Diane Brown, Scott Kogan, Eric Lagasse, Irving Weissman, Myriam Alcalay, Pier Giuseppe Pelicci, Susan Atwater, and J. Michael Bishop Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2551–2556. PMCID: PMC20126 Obesity increases sensitivity to endotoxin liver injury: Implications for the pathogenesis of steatohepatitis Shi Qi Yang, Hui Zhi Lin, M. Daniel Lane, Mark Clemens, and Anna Mae Diehl Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2557–2562. PMCID: PMC20127 EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia Chi Wai So, Carlos Caldas, Meng-Min Liu, Sai-Juan Chen, Qiu-Hua Huang, Long-Jun Gu, Mai Har Sham, Leanne Marie Wiedemann, and Li Chong Chan Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2563–2568. PMCID: PMC20128 Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: Evidence from a novel positron emission tomography method A. Breier, T.-P. Su, R. Saunders, R. E. Carson, B. S. Kolachana, A. de Bartolomeis, D. R. Weinberger, N. Weisenfeld, A. K. Malhotra, W. C. Eckelman, and D. Pickar Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2569–2574. PMCID: PMC20129 Transgenic mice expressing rabbit C-reactive protein are resistant to endotoxemia Dongyuan Xia and David Samols Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2575–2580. PMCID: PMC20130 The quinone reductase gene: A unique estrogen receptor-regulated gene that is activated by antiestrogens Monica M. Montano and Benita S. Katzenellenbogen Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2581–2586. PMCID: PMC20131 Insertion of the adenoviral E3 region into a recombinant viral vector prevents antiviral humoral and cellular immune responses and permits long-term gene expression Yaron Ilan, Gustavo Droguett, Namita Roy Chowdhury, Yongan Li, Krishna Sengupta, Narsing R. Thummala, Anne Davidson, Jayanta Roy Chowdhury, and Marshall S. Horwitz Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2587–2592. PMCID: PMC20132 UDP activates a mucosal-restricted receptor on human nasal epithelial cells that is distinct from the P2Y 2receptor Eduardo R. Lazarowski, Anthony M. Paradiso, William C. Watt, T. Kendall Harden, and Richard C. Boucher Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2599–2603. PMCID: PMC20134 In vivo activation of the cystic fibrosis transmembrane conductance regulator mutant ΔF508 in murine nasal epithelium Thomas J. Kelley, Kirk Thomas, Laura J. H. Milgram, and Mitchell L. Drumm Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2604–2608. PMCID: PMC20135 Pivotal role for the NFIL3/E4BP4 transcription factor in interleukin 3-mediated survival of pro-B lymphocytes Satoshi Ikushima, Takeshi Inukai, Toshiya Inaba, Stephen D. Nimer, John L. Cleveland, and A. Thomas Look Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2609–2614. PMCID: PMC20136 Calorie restriction reduces the incidence of myeloid leukemia induced by a single whole-body radiation in C3H/He mice Kazuko Yoshida, Tohru Inoue, Kumie Nojima, Yoko Hirabayashi, and Toshihiko Sado Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2615–2619. PMCID: PMC20137 Mixed-backbone oligonucleotides as second generation antisense oligonucleotides: In vitro and in vivostudies Sudhir Agrawal, Zhiwei Jiang, Qiuyan Zhao, Denise Shaw, Qiuyin Cai, Allysen Roskey, Lakshmi Channavajjala, Carl Saxinger, and Ruiwen Zhang Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2620–2625. PMCID: PMC20138 Microbiology A genetic system for Archaea of the genus Methanosarcina: Liposome-mediated transformation and construction of shuttle vectors William W. Metcalf, Jun Kai Zhang, Ethel Apolinario, Kevin R. Sowers, and Ralph S. Wolfe Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2626–2631. PMCID: PMC20139 Neurobiology Barx2, a new homeobox gene of the Bar class, is expressed in neural and craniofacial structures during development Frederick S. Jones, Chrissa Kioussi, Donald W. Copertino, Pekka Kallunki, Brent D. Holst, and Gerald M. Edelman Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2632–2637. PMCID: PMC20140 A novel seizure-induced synaptotagmin gene identified by differential display Joseph M. Babity, John N. Armstrong, J.-Christophe L. Plumier, R. William Currie, and Harold A. Robertson Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2638–2641. PMCID: PMC20141 Transcription factor NF-κB is activated in primary neurons by amyloid β peptides and in neurons surrounding early plaques from patients with Alzheimer disease Barbara Kaltschmidt, Martin Uherek, Benedikt Volk, Patrick A. Baeuerle, and Christian Kaltschmidt Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2642–2647. PMCID: PMC20142 Neuritin: A gene induced by neural activity and neurotrophins that promotes neuritogenesis Gregory S. Naeve, Meena Ramakrishnan, Rainer Kramer, Dana Hevroni, Yoav Citri, and Lars E. Theill Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2648–2653. PMCID: PMC20143 Induction by agrin of ectopic and functional postsynaptic-like membrane in innervated muscle G. Jones, T. Meier, M. Lichtsteiner, V. Witzemann, B. Sakmann, and H. R. Brenner Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2654–2659. PMCID: PMC20144 The location of the cochlear amplifier: Spatial representation of a single tone on the guinea pig basilar membrane I. J. Russell and K. E. Nilsen Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2660–2664. PMCID: PMC20145 Decreased probability of neurotransmitter release underlies striatal long-term depression and postnatal development of corticostriatal synapses Sukwoo Choi and David M. Lovinger Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2665–2670. PMCID: PMC20146 Dual activity maps in primate visual cortex produced by different temporal patterns of zif268 mRNA and protein expression Avi Chaudhuri, Jonathan Nissanov, Sylvie Larocque, and Lise Rioux Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2671–2675. PMCID: PMC20147 Neuronal (type I) nitric oxide synthase regulates nuclear factorκB activity and immunologic (type II) nitric oxide synthase expression Hitoshi Togashi, Masayuki Sasaki, Elliot Frohman, Eichi Taira, Rajiv R. Ratan, Ted M. Dawson, and Valina L. Dawson Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2676–2680. PMCID: PMC20148 Hyperresponsive febrile reactions to interleukin (IL) 1α and IL-1β, and altered brain cytokine mRNA and serum cytokine levels, in IL-1β-deficient mice Katarina Alheim, Zhen Chai, Giamila Fantuzzi, Homa Hasanvan, David Malinowsky, Elena Di Santo, Pietro Ghezzi, Charles A. Dinarello, and Tamas Bartfai Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2681–2686. PMCID: PMC20149 Glucocorticoid receptor pathways are involved in the inhibition of astrocyte proliferation Kathryn L. Crossin, Ming-Hong Tai, Leslie A. Krushel, Vincent P. Mauro, and Gerald M. Edelman Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2687–2692. PMCID: PMC20150 Antisense oligodeoxynucleotide-mediated disruption of hippocampal cAMP response element binding protein levels impairs consolidation of memory for water maze training John F. Guzowski and James L. McGaugh Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2693–2698. PMCID: PMC20151 In vivo 13C NMR measurements of cerebral glutamine synthesis as evidence for glutamate–glutamine cycling N. R. Sibson, A. Dhankhar, G. F. Mason, K. L. Behar, D. L. Rothman, and R. G. Shulman Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2699–2704. PMCID: PMC20152 Pharmacology Regulation of intestinal uroguanylin/guanylin receptor-mediated responses by mucosal acidity F. Kent Hamra, Sammy L. Eber, David T. Chin, Mark G. Currie, and Leonard R. Forte Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2705–2710. PMCID: PMC20153 A surface on the G protein β-subunit involved in interactions with adenylyl cyclases Yibang Chen, Gezhi Weng, Jinrong Li, Anya Harry, Joseph Pieroni, Jane Dingus, John D. Hildebrandt, Frank Guarnieri, Harel Weinstein, and Ravi Iyengar Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2711–2714. PMCID: PMC20154 Irreversible antagonism of 5HT2c receptors by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) Y. G. Ni, N. Camacho, and R. Miledi Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2715–2718. PMCID: PMC20155 Alprazolam dependence prevented by substituting with the β-carboline abecarnil Graziano Pinna, Ruggero Galici, Herbert H. Schneider, David N. Stephens, and Lechoslaw Turski Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2719–2723. PMCID: PMC20156 Regulation of sodium channel gene expression by class I antiarrhythmic drugs and n − 3 polyunsaturated fatty acids in cultured neonatal rat cardiac myocytes Jing X. Kang, Yunyuan Li, and Alexander Leaf Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2724–2728. PMCID: PMC20157 Physiology A mutation in autosomal dominant myotonia congenita affects pore properties of the muscle chloride channel Christoph Fahlke, Carol L. Beck, and Alfred L. George, Jr. Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2729–2734. PMCID: PMC20158 Targeting transforming growth factor α expression to discrete loci of the neuroendocrine brain induces female sexual precocity Florence Rage, Diane F. Hill, Miguel Sena-Esteves, Xandra O. Breakefield, Robert J. Coffey, Maria E. Costa, Samuel M. McCann, and Sergio R. Ojeda Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2735–2740. PMCID: PMC20159 Oxytocin stimulates the release of luteinizing hormone-releasing hormone from medial basal hypothalamic explants by releasing nitric oxide V. Rettori, G. Canteros, R. Renoso, M. Gimeno, and S. M. McCann Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2741–2744. PMCID: PMC20160 Plant Biology Cell proliferation and hair tip growth in the Arabidopsis root are under mechanistically different forms of redox control Rocío Sánchez-Fernández, Mark Fricker, Liz B. Corben, Nick S. White, Nicki Sheard, Christopher J. Leaver, Marc Van Montagu, Dirk Inzé, and Mike J. May Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2745–2750. PMCID: PMC20161 Receptor-mediated activation of a plant Ca 2+-permeable ion channel involved in pathogen defense Sabine Zimmermann, Thorsten Nürnberger, Jean-Marie Frachisse, Wolfgang Wirtz, Jean Guern, Rainer Hedrich, and Dierk Scheel Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2751–2755. PMCID: PMC20162 Ethylene can stimulate Arabidopsis hypocotyl elongation in the light Jan Smalle, Mira Haegman, Jasmina Kurepa, Marc Van Montagu, and Dominique Van Der Straeten Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2756–2761. PMCID: PMC20163 Population Biology Early mortality surge in protein-deprived females causes reversal
of sex differential of life expectancy in Mediterranean fruit flies Hans-Georg Müller, Jane-Ling Wang, William B. Capra, Pablo Liedo, and James R. Carey Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2762–2765. PMCID: PMC20164 Social Sciences Psychology Severe spatial navigation deficit in the Morris water maze after single high dose of neonatal x-ray irradiation in the rat András Czurkó, Boldizsár Czéh, László Seress, Lynn Nadel, and Jan Bures Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2766–2771. PMCID: PMC20165 Social Sciences Chronic disability trends in elderly United States populations: 1982–1994 Kenneth G. Manton, Larry Corder, and Eric Stallard Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2593–2598. PMCID: PMC20133 Correction Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2772. PMCID: PMC56216 Corrects: H Goldfine, et al. Membrane permeabilization by Listeria monocytogenes phosphatidylinositol-specific phospholipase C is independent of phospholipid hydrolysis and cooperative with listeriolysin O. Proc Natl Acad Sci U S A. 1995 March 28; 92(7): 2979–2983. |