| | This journal provides immediate access to some articles. From the Academy Introduction to “From the Academy”  Nicholas R. Cozzarelli PMCID: PMC34136 The U.S. National Academy of Sciences—In service to science and  society Jack Halpern PMCID: PMC34137 Opportunities await Ronald L. Phillips PMCID: PMC34138 Colleges of agriculture at the land grant universities: Public
service and public policy PMCID: PMC34139 Workshop on Schizophrenia Samuel H. Barondes, Bruce M. Alberts, Nancy C. Andreasen, Cornelia Bargmann, Francine Benes, Patricia Goldman-Rakic, Irving Gottesman, Stephen F. Heinemann, Edward G. Jones, Marc Kirschner, David Lewis, Martin Raff, Allen Roses, John Rubenstein, Solomon Snyder, Stanley J. Watson, Daniel R. Weinberger, and Robert H. Yolken PMCID: PMC34140 Commentaries Expression pattern of HIV-1 coreceptors on T cells: Implications for viral transmission and lymphocyte homing Derya Unutmaz and Dan R. Littman PMCID: PMC34141 Choosing the right sugar: How polymerases select a
nucleotide substrate Catherine M. Joyce PMCID: PMC34142 Physical Sciences Chemistry Analysis of highly disfavored processes through pathway-specific correlated fluorescence James J. La Clair PMCID: PMC19966 Rapid, sensitive structure analysis of oligosaccharides Yingming Zhao, Stephen B. H. Kent, and Brian T. Chait PMCID: PMC19967 Computer Sciences Ensemble quantum computing by NMR spectroscopy David G. Cory, Amr F. Fahmy, and Timothy F. Havel PMCID: PMC19968 Biological Sciences Agricultural Sciences One gene in diamondback moth confers resistance to four Bacillus thuringiensistoxins Bruce E. Tabashnik, Yong-Biao Liu, Naomi Finson, Luke Masson, and David G. Heckel PMCID: PMC19969 Applied Biological Sciences Persistence in muscle of an adenoviral vector that lacks all viral genes Hsiao-Huei Chen, Lisa M. Mack, Robert Kelly, Marcia Ontell, Stefan Kochanek, and Paula R. Clemens PMCID: PMC19970 Gene transfer by guanidinium-cholesterol cationic lipids into airway epithelial cells in vitro and invivoNoufissa Oudrhiri, Jean-Pierre Vigneron, Michel Peuchmaur, Tony Leclerc, Jean-Marie Lehn, and Pierre Lehn PMCID: PMC19971 Biochemistry A mixed-charge pair in human interleukin 4 dominates high-affinity interaction with the receptor α chain Yonghong Wang, Bo-Jiang Shen, and Walter Sebald PMCID: PMC19972 “Peptabody”: A new type of high avidity binding protein Alexey V. Terskikh, Jean-Marc Le Doussal, Reto Crameri, Igor Fisch, Jean-Pierre Mach, and Andrey V. Kajava PMCID: PMC19973 Unexpected genetic and structural relationships of a long-forgotten flavoenzyme to NAD(P)H:quinone reductase (DT-diaphorase) Qinjian Zhao, Xiao Ling Yang, W. David Holtzclaw, and Paul Talalay PMCID: PMC19974 Daidzin inhibits mitochondrial aldehyde dehydrogenase and suppresses ethanol intake of Syrian golden hamsters Wing Ming Keung, Anatole A. Klyosov, and Bert L. Vallee PMCID: PMC19975 Development of “substrate-trapping” mutants to identify physiological substrates of protein tyrosine phosphatases Andrew J. Flint, Tony Tiganis, David Barford, and Nicholas K. Tonks PMCID: PMC19976 Conformation-dependent phosphorylation of p53 Victor Adler, Matthew R. Pincus, Toshinari Minamoto, Serge Y. Fuchs, Mark J. Bluth, Paul W. Brandt-Rauf, Fred K. Friedman, Richard C. Robinson, James M. Chen, Xin Wei Wang, Curtis C. Harris, and Ze’ev Ronai PMCID: PMC19977 Chirality of DNA trefoils: Implications in intramolecular synapsis of distant DNA segments Stanley Y. Shaw and James C. Wang PMCID: PMC19978 Detection of changes in pairwise interactions during allosteric transitions: Coupling between local and global conformational changes in GroEL Amir Aharoni and Amnon Horovitz PMCID: PMC19979 A Xenopus oocyte β subunit: Evidence for a role in the assembly/expression of voltage-gated calcium channels that is separate from its role as a regulatory subunit Erwin Tareilus, Michel Roux, Ning Qin, Riccardo Olcese, Jianming Zhou, Enrico Stefani, and Lutz Birnbaumer PMCID: PMC19980 The two α subunits of Escherichia coli RNA polymerase are asymmetrically arranged and contact different halves of the DNA upstream element Katsuhiko Murakami, Makoto Kimura, Jeffrey T. Owens, Claude F. Meares, and Akira Ishihama PMCID: PMC19981 Structure and function in rhodopsin: Peptide sequences in the cytoplasmic loops of rhodopsin are intimately involved in interaction with rhodopsin kinase Robin L. Thurmond, Carole Creuzenet, Philip J. Reeves, and H. Gobind Khorana PMCID: PMC19982 Galactose-dependent reversible interaction of Gal3p with Gal80p in the induction pathway of Gal4p-activated genes of SaccharomycescerevisiaeKen-ichi Yano and Toshio Fukasawa PMCID: PMC19983 Gα o is necessary for muscarinic regulation of Ca 2+ channels in mouse heart D. Valenzuela, X. Han, U. Mende, C. Fankhauser, H. Mashimo, P. Huang, J. Pfeffer, E. J. Neer, and M. C. Fishman PMCID: PMC19984 Cloning of murine RNA polymerase I-specific TAF factors: Conserved interactions between the subunits of the species-specific transcription initiation factor TIF-IB/SL1 Jutta Heix, Joost C. B. M. Zomerdijk, Ali Ravanpay, Robert Tjian, and Ingrid Grummt PMCID: PMC19985 A heparin-binding synthetic peptide of heparin/heparan sulfateinteracting protein modulates blood coagulation activities Shouchun Liu, Fanyu Zhou, Magnus Höök, and Daniel D. Carson PMCID: PMC19986 Cytohesin-1, a cytosolic guanine nucleotide-exchange protein for ADP-ribosylation factor Elisabetta Meacci, Su-Chen Tsai, Ronald Adamik, Joel Moss, and Martha Vaughan PMCID: PMC19987 Benzo[ a]pyrene diol epoxide-DNA cis adduct formation through a trans chlorohydrin intermediate Thomas Meehan, Alan R. Wolfe, George R. Negrete, and Qi Song PMCID: PMC19988 Transcriptional arrest: Escherichia coli RNA polymerase translocates backward, leaving the 3′ end of the RNA intact and extruded Natalia Komissarova and Mikhail Kashlev PMCID: PMC19989 Site-specific mutagenesis reveals differences in the structural bases for tight binding of RNase inhibitor to angiogenin and RNase A Chang-Zheng Chen and Robert Shapiro PMCID: PMC19990 Biophysics Electron diffraction studies of light-induced conformational changes in the Leu-93 → Ala bacteriorhodopsin mutant Sriram Subramaniam, A. R. Faruqi, Dieter Oesterhelt, and Richard Henderson PMCID: PMC19991 Cooperative effects of photodynamic treatment of cells in microcolonies Jostein Dahle, Olav Kaalhus, Johan Moan, and Harald B. Steen PMCID: PMC19992 Submillisecond protein folding kinetics studied by ultrarapid mixing Chi-Kin Chan, Yi Hu, Satoshi Takahashi, Denis L. Rousseau, William A. Eaton, and James Hofrichter PMCID: PMC19993 Direct in vivo measurement of targeted binding in a human tumor xenograft David A. Berk, Fan Yuan, Michael Leunig, and Rakesh K. Jain PMCID: PMC19994 Direct phase determination in protein electron crystallography: The pseudo-atom approximation Douglas L. Dorset PMCID: PMC19995 Cell Biology Inhibition by uridine but not thymidine of p53-dependent intestinal apoptosis initiated by 5-fluorouracil: Evidence for the involvement of RNA perturbation D. Mark Pritchard, Alastair J. M. Watson, Christopher S. Potten, Ann L. Jackman, and John A. Hickman PMCID: PMC19996 Na + pump low and high ouabain affinity α subunit isoforms are differently distributed in cells Magdalena Juhaszova and Mordecai P. Blaustein PMCID: PMC19997 Functional interaction of erythropoietin and stem cell factor receptors is essential for erythroid colony formation Hong Wu, Ursula Klingmüller, Adriana Acurio, Jonathan G. Hsiao, and Harvey F. Lodish PMCID: PMC19998 DEK, an autoantigen involved in a chromosomal translocation in acute myelogenous leukemia, binds to the HIV-2 enhancer Glenn K. Fu, Gerard Grosveld, and David M. Markovitz PMCID: PMC19999 Multiple mechanisms of N-phosphonacetyl- l-aspartate resistance in human cell lines: Carbamyl- P synthetase/aspartate transcarbamylase/dihydro-orotase gene amplification is frequent only when chromosome 2 is rearranged Kathleen A. Smith, Olga B. Chernova, Richard P. Groves, Mary B. Stark, José L. Martínez, Jeffrey N. Davidson, Jeffrey M. Trent, Thomas E. Patterson, Archana Agarwal, Pamela Duncan, Munna L. Agarwal, and George R. Stark PMCID: PMC20000 Hepatitis B virus (HBV) envelope glycoproteins vary drastically in their sensitivity to glycan processing: Evidence that alteration of a single N-linked glycosylation site can regulate HBV secretion Anand Mehta, Xuanyong Lu, Timothy M. Block, Baruch S. Blumberg, and Raymond A. Dwek PMCID: PMC20001 GTP-bound forms of rab6 induce the redistribution of Golgi proteins into the endoplasmic reticulum Olivier Martinez, Claude Antony, Gérard Pehau-Arnaudet, Eric G. Berger, Jean Salamero, and Bruno Goud PMCID: PMC20002 Apical sorting of hepatitis B surface antigen (HBsAg) is independent of N-glycosylation and glycosylphosphatidylinositol-anchored protein segregation María Paz Marzolo, Paulina Bull, and Alfonso González PMCID: PMC20003 The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage Kevin D. Brown, Yael Ziv, Sunanda N. Sadanandan, Luciana Chessa, Francis S. Collins, Yosef Shiloh, and Danilo A. Tagle PMCID: PMC20004 Developmental Biology Multiple promoter elements differentially regulate the expression of the mouse tenascin gene Donald W. Copertino, Gerald M. Edelman, and Frederick S. Jones PMCID: PMC20005 Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascular development Xin Liu, Hong Wu, Michael Byrne, Stephen Krane, and Rudolf Jaenisch PMCID: PMC20006 Ecology Plant diversity and ecosystem productivity: Theoretical
considerations David Tilman, Clarence L. Lehman, and Kendall T. Thomson PMCID: PMC20007 Evolution Analysis of HIV-1 env gene sequences reveals evidence for a low effective number in the viral population Andrew J. Leigh Brown PMCID: PMC20008 A single and early migration for the peopling of the Americas supported by mitochondrial DNA sequence data Sandro L. Bonatto and Francisco M. Salzano PMCID: PMC20009 Genetics Sequence patterns indicate an enzymatic involvement in integration of mammalian retroposons Jerzy Jurka PMCID: PMC20010 Immunology Requirement for an initial signal from the membrane-proximal region of the interleukin 2 receptor γ c chain for Janus kinase activation leading to T cell proliferation Brad H. Nelson, Bryan C. McIntosh, Lori L. Rosencrans, and Philip D. Greenberg PMCID: PMC20011 Incomplete endoplasmic reticulum (ER) retention in immature thymocytes as revealed by surface expression of “ER-resident” molecular chaperones David L. Wiest, Avinash Bhandoola, Jennifer Punt, Gert Kreibich, David McKean, and Alfred Singer PMCID: PMC20012 Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection David A. Price, Philip J. R. Goulder, Paul Klenerman, Andrew K. Sewell, Philippa J. Easterbrook, Maxine Troop, Charles R. M. Bangham, and Rodney E. Phillips PMCID: PMC20013 Misfolded major histocompatibility complex class I heavy chains are translocated into the cytoplasm and degraded by the proteasome Eric A. Hughes, Craig Hammond, and Peter Cresswell PMCID: PMC20014 The antigen-binding domain of a human IgG-anti-F(ab′) 2autoantibody Martin Welschof, Peter Terness, Sergey M. Kipriyanov, Diana Stanescu, Frank Breitling, Heinz Dörsam, Stefan Dübel, Melvyn Little, and Gerhard Opelz PMCID: PMC20015 Cyclophosphamide/granulocyte colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilization Sean J. Morrison, Douglas E. Wright, and Irving L. Weissman PMCID: PMC20016 A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening Yao-Tseng Chen, Matthew J. Scanlan, Ugur Sahin, Özlem Türeci, Ali O. Gure, Solam Tsang, Barbara Williamson, Elisabeth Stockert, Michael Pfreundschuh, and Lloyd J. Old PMCID: PMC20017 syk kinase activation by a src kinase-initiated activation loop phosphorylation chain reaction O. El-Hillal, T. Kurosaki, H. Yamamura, J.-P. Kinet, and A. M. Scharenberg PMCID: PMC20018 The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes Conrad C. Bleul, Lijun Wu, James A. Hoxie, Timothy A. Springer, and Charles R. Mackay PMCID: PMC20019 Medical Sciences Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: Implications for CD40–CD40 ligand signaling in atherosclerosis François Mach, Uwe Schönbeck, Galina K. Sukhova, Todd Bourcier, Jean-Yves Bonnefoy, Jordan S. Pober, and Peter Libby PMCID: PMC20020 Targeting RNA decay with 2′,5′ oligoadenylate-antisense in respiratory syncytial virus-infected cells Nick M. Cirino, Guiying Li, Wei Xiao, Paul F. Torrence, and Robert H. Silverman PMCID: PMC20021 Antigen presentation in retroviral vector-mediated gene transfer invivoElizabeth S. Song, Virginia Lee, Charles D. Surh, Andrea Lynn, Duane Brumm, Douglas J. Jolly, John F. Warner, and Sunil Chada PMCID: PMC20022 Functional characterization of ETV6 and ETV6/CBFA2 in the regulation of the MCSFR proximal promoter S. Fears, M. Gavin, D.-E. Zhang, C. Hetherington, Y. Ben-David, J. D. Rowley, and G. Nucifora PMCID: PMC20023 Peptide inhibition of glomerular deposition of an anti-DNA antibody Bruce Gaynor, Chaim Putterman, Philippe Valadon, Linda Spatz, Matthew D. Scharff, and Betty Diamond PMCID: PMC20024 Transfection and overexpression of the calcium binding protein calbindin-D 28k results in a stimulatory effect on insulin synthesis in a rat β cell line (RIN 1046-38) Daphne Reddy, Allan S. Pollock, Samuel A. Clark, Karen Sooy, Rupangi C. Vasavada, Andrew F. Stewart, Thomas Honeyman, and Sylvia Christakos PMCID: PMC20025 Glutathione deficiency is associated with impaired survival in HIV disease Leonore A. Herzenberg, Stephen C. De Rosa, J. Gregson Dubs, Mario Roederer, Michael T. Anderson, Stephen W. Ela, Stanley C. Deresinski, and Leonard A. Herzenberg PMCID: PMC20026 A genetic analysis of integrin function: Glanzmann thrombasthenia invitroElizabeth K. Baker, Eileen Collins Tozer, Martin Pfaff, Sanford J. Shattil, Joseph C. Loftus, and Mark H. Ginsberg PMCID: PMC20027 Microbiology σ 54, a vital protein for MyxococcusxanthusIngrid M. Keseler and Dale Kaiser PMCID: PMC20028 Neurobiology Instrumental conditioning of fast (20- to 50-Hz) oscillations in corticothalamic networks Florin Amzica, Dag Neckelmann, and Mircea Steriade PMCID: PMC20029 Differential pre- and postsynaptic modulation of chemical transmission in the squid giant synapse by tyrosine phosphorylation Rodolfo Llinás, Herman Moreno, Mutsuyuki Sugimori, Moosa Mohammadi, and Joseph Schlessinger PMCID: PMC20030 Identification of components of a phosphoinositide signaling pathway in retinal rod outer segments Y.-W. Peng, S. G. Rhee, W.-P. Yu, Y.-K. Ho, T. Schoen, G. J. Chader, and K.-W. Yau PMCID: PMC20031 Changes in multiple brain regions underlie species differences in a complex, congenital behavior Evan Balaban PMCID: PMC20032 Inhibition of interleukin 1β converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage Hideaki Hara, Robert M. Friedlander, Valeria Gagliardini, Cenk Ayata, Klaus Fink, Zhihong Huang, Masao Shimizu-Sasamata, Junying Yuan, and Michael A. Moskowitz PMCID: PMC20033 d-aspartate localizations imply neuronal and neuroendocrine roles Michael J. Schell, Odelia B. Cooper, and Solomon H. Snyder PMCID: PMC20034 Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models Joseph P. Steiner, Gregory S. Hamilton, Douglas T. Ross, Heather L. Valentine, Hongzhi Guo, Maureen A. Connolly, Shi Liang, Cynthia Ramsey, Jia-He J. Li, Wei Huang, Pamela Howorth, Rajat Soni, Michael Fuller, Hans Sauer, Alison C. Nowotnik, and Peter D. Suzdak PMCID: PMC20035 The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid β protein ending at the 42nd (or 43rd) residue Taisuke Tomita, Kei Maruyama, Takaomi C. Saido, Hideaki Kume, Kohki Shinozaki, Shinya Tokuhiro, Anja Capell, Jochen Walter, Jürgen Grünberg, Christian Haass, Takeshi Iwatsubo, and Kunihiko Obata PMCID: PMC20036 Pharmacology Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine Alex Sparreboom, Judith van Asperen, Ulrich Mayer, Alfred H. Schinkel, Johan W. Smit, Dirk K. F. Meijer, Piet Borst, Willem J. Nooijen, Jos H. Beijnen, and Olaf van Tellingen PMCID: PMC20037 Blockage of 5HT 2C serotonin receptors by fluoxetine (Prozac) Y. G. Ni and R. Miledi PMCID: PMC20038 Blockage of muscle and neuronal nicotinic acetylcholine receptors by fluoxetine (Prozac) J. García-Colunga, J. N. Awad, and R. Miledi PMCID: PMC20039 Physiology Pore size of the malaria parasite’s nutrient channel Sanjay A. Desai and Robert L. Rosenberg PMCID: PMC20040 Cloning of cDNA and estrogen-induced hepatic gene expression for choriogenin H, a precursor protein of the fish egg envelope (chorion) Kenji Murata, Hitoshi Sugiyama, Shigeki Yasumasu, Ichiro Iuchi, Ikuo Yasumasu, and Kenjiro Yamagami PMCID: PMC20041 Prostate enlargement in mice due to fetal exposure to low doses of estradiol or diethylstilbestrol and opposite effects at high doses Frederick S. vom Saal, Barry G. Timms, Monica M. Montano, Paola Palanza, Kristina A. Thayer, Susan C. Nagel, Minati D. Dhar, V. K. Ganjam, Stefano Parmigiani, and Wade V. Welshons PMCID: PMC20042 Working underground: Respiratory adaptations in the blind mole rat Hans R. Widmer, Hans Hoppeler, Eviatar Nevo, C. Richard Taylor, and Ewald R. Weibel PMCID: PMC20043 Somatotropic actions of the homologous growth hormone and prolactins in the euryhaline teleost, the tilapia, OreochromismossambicusBrian S. Shepherd, Tatsuya Sakamoto, Richard S. Nishioka, Nurney H. Richman, III, Ikue Mori, Steffen S. Madsen, Thomas T. Chen, Tetsuya Hirano, Howard A. Bern, and E. Gordon Grau PMCID: PMC20044 Plant Biology A mutation in the putative RNA polymerase gene inhibits nonhomologous, but not homologous, genetic recombination in an RNA virus M. Figlerowicz, P. D. Nagy, and J. J. Bujarski PMCID: PMC20045 Rapid, transient, and highly localized induction of plastidial ω-3 fatty acid desaturase mRNA at fungal infection sites in PetroselinumcrispumChristoph Kirsch, Monica Takamiya-Wik, Susanne Reinold, Klaus Hahlbrock, and Imre E. Somssich PMCID: PMC20046 The MUR1 gene of Arabidopsis thaliana encodes an isoform of GDP- d-mannose-4,6-dehydratase, catalyzing the first step in the de novo synthesis of GDP- l-fucose Christopher P. Bonin, Ian Potter, Gary F. Vanzin, and Wolf-Dieter Reiter PMCID: PMC20047 |
