| | This journal provides immediate access to some articles. From the Academy Academy Honors 17 for Major
Contributions to Science Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1173–1174. PMCID: PMC33551 Commentaries An arrayable flow-through microcentrifuge for high-throughput
instrumentation–a matter of scale Thomas M. Laue Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1163. PMCID: PMC33547 1918 Spanish influenza: The secrets remain elusive Robert G. Webster Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1164–1166. PMCID: PMC33548 Malaria vaccines Anthony A. Holder Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1167–1169. PMCID: PMC33549 Genetic isolates: Separate but equal? Leonid Kruglyak Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1170–1172. PMCID: PMC33550 Perspective Nitrogen fertilizer: Retrospect and prospect Charles R. Frink, Paul E. Waggoner, and Jesse H. Ausubel Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1175–1180. PMCID: PMC33552 Physical Sciences Chemistry Accelerated chemical synthesis of peptides and small proteins Les P. Miranda and Paul F. Alewood Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1181–1186. PMCID: PMC15437 Femtosecond dynamics of the DNA intercalator ethidium and
electron transfer with mononucleotides in water Torsten Fiebig, Chaozhi Wan, Shana O. Kelley, Jacqueline K. Barton, and Ahmed H. Zewail Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1187–1192. PMCID: PMC15438 INAUGURAL ARTICLE by a Recently Elected Academy Member: Brominated 7-hydroxycoumarin-4-ylmethyls: Photolabile protecting
groups with biologically useful cross-sections for two photon
photolysis Toshiaki Furuta, Samuel S.-H. Wang, Jami L. Dantzker, Timothy M. Dore, Wendy J. Bybee, Edward M. Callaway, Winfried Denk, and Roger Y. Tsien Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1193–1200. PMCID: PMC15439 Volatile buffers can override the “pH memory” of subtilisin
catalysis in organic media Evagelos Zacharis, Peter J. Halling, and D. Gareth Rees Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1201–1205. PMCID: PMC15440 Geophysics INAUGURAL ARTICLE by a Recently Elected Academy Member: Separation of a midlevel density current from the
bottom of a continental slope M. E. Stern Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1206–1211. PMCID: PMC15441 Biological Sciences Applied Biological Sciences Volatile buffers can override the “pH memory” of subtilisin
catalysis in organic media Evagelos Zacharis, Peter J. Halling, and D. Gareth Rees Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1201–1205. PMCID: PMC15440 A plant virus-encoded protein facilitates long-distance movement
of heterologous viral RNA Eugene V. Ryabov, David J. Robinson, and Michael E. Taliansky Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1212–1217. PMCID: PMC15442 Biochemistry Structure-activity analysis of synthetic autoinducing thiolactone
peptides from Staphylococcus aureus responsible
for virulence Patricia Mayville, Guangyong Ji, Ronald Beavis, Hongmei Yang, Michael Goger, Richard P. Novick, and Tom W. Muir Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1218–1223. PMCID: PMC15443 Receptor-induced polymerization of coatomer Constanze Reinhard, Cordula Harter, Martina Bremser, Britta Brügger, Kai Sohn, J. Bernd Helms, and Felix Wieland Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1224–1228. PMCID: PMC15444 Nuclear localization of the C1 factor (host cell factor) in
sensory neurons correlates with reactivation of herpes simplex virus
from latency Thomas M. Kristie, Jodi L. Vogel, and Amy E. Sears Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1229–1233. PMCID: PMC15445 Two differently regulated nuclear factor κB activation pathways
triggered by the cytoplasmic tail of CD40 Nobuo Tsukamoto, Norihiko Kobayashi, Sakura Azuma, Tadashi Yamamoto, and Jun-ichiro Inoue Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1234–1239. PMCID: PMC15446 Principles of quasi-equivalence and Euclidean geometry govern the
assembly of cubic and dodecahedral cores of pyruvate
dehydrogenase complexes Tina Izard, Arnthor Ævarsson, Mark D. Allen, Adrie H. Westphal, Richard N. Perham, Aart de Kok, and Wim G. J. Hol Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1240–1245. PMCID: PMC15447 Opposing actions of intact and N-terminal fragments of the human
prolactin/growth hormone family members on angiogenesis: An
efficient mechanism for the regulation of angiogenesis Ingrid Struman, Frauke Bentzien, Hsinyu Lee, Véronique Mainfroid, Gisela D’Angelo, Vincent Goffin, Richard I. Weiner, and Joseph A. Martial Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1246–1251. PMCID: PMC15448 Dissecting Fas signaling with an altered-specificity death-domain
mutant: Requirement of FADD binding for apoptosis but not Jun N-terminal kinase activation Howard Y. Chang, Xiaolu Yang, and David Baltimore Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1252–1256. PMCID: PMC15449 Crystal structure of a dimeric chymotrypsin inhibitor 2
mutant containing an inserted glutamine repeat Yu Wai Chen, Kelvin Stott, and Max F. Perutz Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1257–1261. PMCID: PMC15450 Structure, thermostability, and conformational flexibility of hen
egg-white lysozyme dissolved in glycerol Tatyana Knubovets, John J. Osterhout, Peter J. Connolly, and Alexander M. Klibanov Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1262–1267. PMCID: PMC15451 Cooperative binding of ATP and MgADP in the sulfonylurea receptor
is modulated by glibenclamide Kazumitsu Ueda, Jun Komine, Michinori Matsuo, Susumu Seino, and Teruo Amachi Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1268–1272. PMCID: PMC15452 Folding pathway of a lattice model for proteins Vijay S. Pande and Daniel S. Rokhsar Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1273–1278. PMCID: PMC15453 Role of calpain in adipocyte differentiation Yashomati M. Patel and M. Daniel Lane Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1279–1284. PMCID: PMC15454 Interactions between human cyclin T, Tat, and the transactivation
response element (TAR) are disrupted by a cysteine to tyrosine
substitution found in mouse cyclin T Koh Fujinaga, Ran Taube, Jörg Wimmer, Thomas P. Cujec, and B. Matija Peterlin Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1285–1290. PMCID: PMC15455 Modulation of type M2 pyruvate kinase activity by the
human papillomavirus type 16 E7 oncoprotein Werner Zwerschke, Sybille Mazurek, Paola Massimi, Lawrence Banks, Erich Eigenbrodt, and Pidder Jansen-Dürr Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1291–1296. PMCID: PMC15456 The charged region of Hsp90 modulates the function of the
N-terminal domain Thomas Scheibel, Heiko Ingo Siegmund, Rainer Jaenicke, Peter Ganz, Hauke Lilie, and Johannes Buchner Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1297–1302. PMCID: PMC15457 A role for FEN-1 in nonhomologous DNA end joining: The order of
strand annealing and nucleolytic processing events Xiantuo Wu, Thomas E. Wilson, and Michael R. Lieber Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1303–1308. PMCID: PMC15458 Dimethylallyl pyrophosphate is not the committed precursor of
isopentenyl pyrophosphate during terpenoid biosynthesis from
1-deoxyxylulose in higher plants Duilio Arigoni, Wolfgang Eisenreich, Christoph Latzel, Silvia Sagner, Tanja Radykewicz, Meinhart H. Zenk, and Adelbert Bacher Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1309–1314. PMCID: PMC15459 The retinitis pigmentosa GTPase regulator, RPGR, interacts with
the delta subunit of rod cyclic GMP phosphodiesterase Marco Linari, Marius Ueffing, Forbes Manson, Alan Wright, Thomas Meitinger, and Jörg Becker Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1315–1320. PMCID: PMC15460 Mammalian subtilisin/kexin isozyme SKI-1: A widely
expressed proprotein convertase with a unique cleavage specificity and
cellular localization Nabil G. Seidah, Seyed J. Mowla, Josée Hamelin, Aida M. Mamarbachi, Suzanne Benjannet, Barry B. Touré, Ajoy Basak, Jon Scott Munzer, Jadwiga Marcinkiewicz, Mei Zhong, Jean-Christophe Barale, Claude Lazure, Richard A. Murphy, Michel Chrétien, and Mieczyslaw Marcinkiewicz Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1321–1326. PMCID: PMC15461 Posttranslational modification of Gαo1 generates
Gαo3, an abundant G protein in brain Torsten Exner, Ole N. Jensen, Matthias Mann, Christiane Kleuss, and Bernd Nürnberg Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1327–1332. PMCID: PMC15462 The neurotransmitter receptor-anchoring protein gephyrin
reconstitutes molybdenum cofactor biosynthesis in bacteria, plants,
and mammalian cells B. Stallmeyer, G. Schwarz, J. Schulze, A. Nerlich, J. Reiss, J. Kirsch, and R. R. Mendel Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1333–1338. PMCID: PMC15463 rRNA-complementarity in the 5′ untranslated region of mRNA
specifying the Gtx homeodomain protein: Evidence that base- pairing to
18S rRNA affects translational efficiency Michael C.-Y. Hu, Pedro Tranque, Gerald M. Edelman, and Vincent P. Mauro Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1339–1344. PMCID: PMC15464 Histone modification governs the cell cycle regulation of a
replication-independent chromatin assembly pathway in
Saccharomyces cerevisiae Brent A. Altheim and Michael C. Schultz Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1345–1350. PMCID: PMC15465 Biophysics Forced unfolding of the fibronectin type III module reveals a
tensile molecular recognition switch André Krammer, Hui Lu, Barry Isralewitz, Klaus Schulten, and Viola Vogel Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1351–1356. PMCID: PMC15466 Critical role of conserved proline residues in the transmembrane
segment 4 voltage sensor function and in the gating of L-type
calcium channels Hiroshi Yamaguchi, James N. Muth, Maria Varadi, Arnold Schwartz, and Gyula Varadi Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1357–1362. PMCID: PMC15467 Structural analysis at 2.2 Å of orthorhombic crystals presents
the asymmetry of the allophycocyanin–linker complex,
AP L C7.8, from phycobilisomes of
Mastigocladus laminosusWolfgang Reuter, Georg Wiegand, Robert Huber, and Manuel E. Than Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1363–1368. PMCID: PMC15468 Coevolutionary analysis of resistance-evading peptidomimetic
inhibitors of HIV-1 protease Christopher D. Rosin, Richard K. Belew, Garrett M. Morris, Arthur J. Olson, and David S. Goodsell Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1369–1374. PMCID: PMC15469 Confocal fluorescence coincidence analysis: An approach to ultra
high-throughput screening Thorsten Winkler, Ulrich Kettling, Andre Koltermann, and Manfred Eigen Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1375–1378. PMCID: PMC15470 An approach to long-range electron transfer mechanisms in
metalloproteins: In situ scanning tunneling
microscopy with submolecular resolution Esben P. Friis, Jens E. T. Andersen, Yu. I. Kharkats, A. M. Kuznetsov, R. J. Nichols, J.-D. Zhang, and Jens Ulstrup Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1379–1384. PMCID: PMC15471 Cell Biology A human cell-surface receptor for xenotropic and polytropic
murine leukemia viruses: Possible role in G protein-coupled
signal transduction Jean-Luc Battini, John E. J. Rasko, and A. Dusty Miller Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1385–1390. PMCID: PMC15472 Phosphorylation of presenilin-2 regulates its cleavage by
caspases and retards progression of apoptosis Jochen Walter, Alice Schindzielorz, Jürgen Grünberg, and Christian Haass Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1391–1396. PMCID: PMC15473 Differential regulation of maternal vs. paternal centrosomes Xingyong Wu and Robert E. Palazzo Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1397–1402. PMCID: PMC15474 Catalytic subunit of DNA-dependent protein kinase: Impact on
lymphocyte development and tumorigenesis Akihiro Kurimasa, Honghai Ouyang, Li-jin Dong, Sa Wang, Xiaoling Li, Carlos Cordon-Cardo, David J. Chen, and Gloria C. Li Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1403–1408. PMCID: PMC15475 Identification of SSF1, CNS1, and
HCH1 as multicopy suppressors of a Saccharomyces
cerevisiae Hsp90 loss-of-function mutation Debra F. Nathan, Melissa Harju Vos, and Susan Lindquist Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1409–1414. PMCID: PMC15476 Mechanism of biological synergy between cellular Src and
epidermal growth factor receptor David A. Tice, Jacqueline S. Biscardi, Amanda L. Nickles, and Sarah J. Parsons Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1415–1420. PMCID: PMC15477 Specificities of CD40 signaling: Involvement of TRAF2 in
CD40-induced NF-κB activation and intercellular adhesion
molecule-1 up-regulation Ho H. Lee, Paul W. Dempsey, Thomas P. Parks, Xiaoqing Zhu, David Baltimore, and Genhong Cheng Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1421–1426. PMCID: PMC15478 G1 cell cycle arrest and apoptosis induction
by nuclear Smad4/Dpc4: Phenotypes reversed by a tumorigenic mutation Jia Le Dai, Ravi K. Bansal, and Scott E. Kern Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1427–1432. PMCID: PMC15479 Identification of the cyclin D1 gene as a target of activating
transcription factor 2 in chondrocytes Frank Beier, Richard J. Lee, Allison C. Taylor, Richard G. Pestell, and Phyllis LuValle Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1433–1438. PMCID: PMC15480 The molecular chaperone Hsp90 can negatively regulate the
activity of a glucocorticosteroid-dependent promoter Kwang Il Kang, Xia Meng, Jocelyne Devin-Leclerc, Ilham Bouhouche, Ahmed Chadli, Françoise Cadepond, Etienne-Emile Baulieu, and Maria-Grazia Catelli Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1439–1444. PMCID: PMC15481 Developmental Biology Head-specific gene expression in Hydra:
Complexity of DNA– protein interactions at the promoter of
ks1 is inversely correlated to the head
activation potential Ingrid Endl, Jan U. Lohmann, and Thomas C. G. Bosch Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1445–1450. PMCID: PMC15482 Targeted disruption of gene function in Drosophila
by RNA interference (RNA-i): A role for nautilus in
embryonic somatic muscle formation Leonie Misquitta and Bruce M. Paterson Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1451–1456. PMCID: PMC15483 Expression of a murine homologue of the inhibitor of
apoptosis protein is related to cell proliferation Koichi Kobayashi, Masahiko Hatano, Masayuki Otaki, Takeshi Ogasawara, and Takeshi Tokuhisa Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1457–1462. PMCID: PMC15484 Ecology Biodiversity and ecosystem productivity in a
fluctuating environment: The insurance hypothesis Shigeo Yachi and Michel Loreau Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1463–1468. PMCID: PMC15485 Evolution Organization of an echinoderm Hox gene cluster Pedro Martinez, Jonathan P. Rast, César Arenas-Mena, and Eric H. Davidson Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1469–1474. PMCID: PMC15486 Patterns of nucleotide substitution in Drosophila
and mammalian genomes Dmitri A. Petrov and Daniel L. Hartl Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1475–1479. PMCID: PMC15487 Genetics The Arabidopsis thaliana proton transporters,
AtNhx1 and Avp1, can function in cation detoxification in yeast Roberto A. Gaxiola, Rajini Rao, Amir Sherman, Paula Grisafi, Seth L. Alper, and Gerald R. Fink Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1480–1485. PMCID: PMC15488 Global response of Saccharomyces cerevisiae
to an alkylating agent Scott A. Jelinsky and Leona D. Samson Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1486–1491. PMCID: PMC15489 Lethal mutagenesis of HIV with mutagenic nucleoside analogs Lawrence A. Loeb, John M. Essigmann, Farhad Kazazi, Jue Zhang, Karl D. Rose, and James I. Mullins Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1492–1497. PMCID: PMC15492 The [URE3] prion is an aggregated form of Ure2p that can be
cured by overexpression of Ure2p fragments Herman K. Edskes, Vaughn T. Gray, and Reed B. Wickner Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1498–1503. PMCID: PMC15494 Triplet repeats form secondary structures that escape DNA repair
in yeast Hutton Moore, Patricia W. Greenwell, Chin-Pin Liu, Norman Arnheim, and Thomas D. Petes Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1504–1509. PMCID: PMC15496 The identification of markers segregating with resistance to
Schistosoma mansoni infection in the snail
Biomphalaria glabrata Matty Knight, Andre N. Miller, Carolyn N. Patterson, Christopher G. Rowe, George Michaels, Daniel Carr, Charles S. Richards, and Fred A. Lewis Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1510–1515. PMCID: PMC15498 Trapping cDNAs encoding secreted proteins from the salivary
glands of the malaria vector
Anopheles gambiae Bruno Arcà, Fabrizio Lombardo, Margareth de Lara Capurro, Alessandra della Torre, George Dimopoulos, Anthony A. James, and Mario Coluzzi Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1516–1521. PMCID: PMC15500 Immunology Odortypes: Their origin and composition Kunio Yamazaki, Gary K. Beauchamp, Alan Singer, Judith Bard, and Edward A. Boyse Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1522–1525. PMCID: PMC15502 Recombination and transcription of the endogenous Ig
heavy chain locus is effected by the Ig heavy chain intronic enhancer
core region in the absence of the matrix attachment regions Eiko Sakai, Andrea Bottaro, Laurie Davidson, Barry P. Sleckman, and Frederick W. Alt Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1526–1531. PMCID: PMC15504 Immune regulatory loops determine productive interactions within
human T lymphocyte–dendritic cell clusters G. Stuhler, A. Zobywalski, F. Grünebach, P. Brossart, V. L. Reichardt, H. Barth, S. Stevanovic, W. Brugger, L. Kanz, and S. F. Schlossman Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1532–1535. PMCID: PMC15506 T cell receptor gene deletion circles identify recent thymic
emigrants in the peripheral T cell pool Fan-kun Kong, Chen-lo H. Chen, Adrien Six, Richard D. Hockett, and Max D. Cooper Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1536–1540. PMCID: PMC15507 GA-binding protein factors, in concert with the coactivator CREB
binding protein/p300, control the induction of the interleukin 16
promoter in T lymphocytes Norbert Bannert, Andris Avots, Michael Baier, Edgar Serfling, and Reinhard Kurth Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1541–1546. PMCID: PMC15509 Multivalent structure of an αβT cell receptor Gemma Fernández-Miguel, Balbino Alarcón, Antonio Iglesias, Horst Bluethmann, Melchor Alvarez-Mon, Eva Sanz, and Antonio de la Hera Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1547–1552. PMCID: PMC15512 Medical Sciences A gene therapy for cancer using intramuscular injection of
plasmid DNA encoding interferon α Holly M. Horton, Deborah Anderson, Pepe Hernandez, Kerry M. Barnhart, Jon A. Norman, and Suezanne E. Parker Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1553–1558. PMCID: PMC15514 On the mechanism by which vascular endothelial cells regulate
their oxygen consumption Emilio Clementi, Guy Charles Brown, Neale Foxwell, and Salvador Moncada Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1559–1562. PMCID: PMC15516 Mutation of Pten/Mmac1 in mice causes neoplasia
in multiple organ systems Katrina Podsypanina, Lora Hedrick Ellenson, Adriana Nemes, Jianguo Gu, Masahito Tamura, Kenneth M. Yamada, Carlos Cordon-Cardo, Giorgio Catoretti, Peter E. Fisher, and Ramon Parsons Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1563–1568. PMCID: PMC15517 Prototypic G protein-coupled receptor for the intestinotrophic
factor glucagon-like peptide 2 Donald G. Munroe, Ashwani K. Gupta, Fatemeh Kooshesh, Tejal B. Vyas, Geihan Rizkalla, Hong Wang, Lidia Demchyshyn, Zhi-Jie Yang, Rajender K. Kamboj, Hongyun Chen, Kirk McCallum, Martin Sumner-Smith, Daniel J. Drucker, and Anna Crivici Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1569–1573. PMCID: PMC15520 Multinuclear solid-state three-dimensional
MRI of bone and synthetic calcium phosphates Yaotang Wu, David A. Chesler, Melvin
J. Glimcher, Leoncio Garrido, Jinxi Wang, Hong J. Jiang, and Jerome
L. Ackerman Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1574–1578. PMCID: PMC15521 Association of HFE protein with transferrin receptor in crypt
enterocytes of human duodenum Abdul Waheed, Seppo Parkkila, Juha Saarnio, Robert E. Fleming, Xiao Yan Zhou, Shunji Tomatsu, Robert S. Britton, Bruce R. Bacon, and William S. Sly Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1579–1584. PMCID: PMC15523 Mouse steroid receptor coactivator-1 is not essential for
peroxisome proliferator-activated receptor α-regulated
gene expression Chao Qi, Yijun Zhu, Jie Pan, Anjana V. Yeldandi, M. Sambasiva Rao, Nobuyo Maeda, V. Subbarao, Sujata Pulikuri, Takashi Hashimoto, and Janardan K. Reddy Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1585–1590. PMCID: PMC15526 Synergy between an antiangiogenic integrin αv
antagonist and an antibody–cytokine fusion protein eradicates
spontaneous tumor metastases Holger N. Lode, Thomas Moehler, Rong Xiang, Alfred Jonczyk, Stephen D. Gillies, David A. Cheresh, and Ralph A. Reisfeld Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1591–1596. PMCID: PMC15528 Regulation of selectin binding activity by cyclization of sialic
acid moiety of carbohydrate ligands on human leukocytes Chikako Mitsuoka, Katsuyuki Ohmori, Naoko Kimura, Akiko Kanamori, Shiro Komba, Hideharu Ishida, Makoto Kiso, and Reiji Kannagi Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1597–1602. PMCID: PMC15530 Target genes of β-catenin–T
cell-factor/lymphoid-enhancer-factor signaling in human colorectal
carcinomas B. Mann, M. Gelos, A. Siedow, M. L. Hanski, A. Gratchev, M. Ilyas, W. F. Bodmer, M. P. Moyer, E. O. Riecken, H. J. Buhr, and C. Hanski Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1603–1608. PMCID: PMC15532 Activating and dominant inactivating c-KIT
catalytic domain mutations in distinct clinical forms of
human mastocytosis B. Jack Longley, Jr., Dean D. Metcalfe, Michael Tharp, Xiaomei Wang, Lynda Tyrrell, Shu-zhuang Lu, David Heitjan, and Yongsheng Ma Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1609–1614. PMCID: PMC15534 Immunogenicity and in vitro protective efficacy of
a recombinant multistage Plasmodium falciparum
candidate vaccine Ya Ping Shi, Seyed E. Hasnain, John B. Sacci, Brian P. Holloway, Hisashi Fujioka, Nirbhay Kumar, Robert Wohlhueter, Stephen L. Hoffman, William E. Collins, and Altaf A. Lal Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1615–1620. PMCID: PMC15536 Allelic association between marker loci C. Lonjou, A. Collins, and N. E. Morton Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1621–1626. PMCID: PMC15538 Human single-chain Fv immunoconjugates targeted to a
melanoma-associated chondroitin sulfate proteoglycan mediate specific
lysis of human melanoma cells by natural killer cells and complement Baiyang Wang, Yi-Bin Chen, Oran Ayalon, Jeffrey Bender, and Alan Garen Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1627–1632. PMCID: PMC15540 Epiregulin is a potent vascular smooth muscle cell-derived
mitogen induced by angiotensin II, endothelin-1, and thrombin David S. Taylor, Xinbo Cheng, John E. Pawlowski, Alison R. Wallace, Patricia Ferrer, and Christopher J. Molloy Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1633–1638. PMCID: PMC15542 Microbiology Quorum sensing in Escherichia coli,
Salmonella typhimurium, and Vibrio
harveyi: A new family of genes responsible for
autoinducer production Michael G. Surette, Melissa B. Miller, and Bonnie L. Bassler Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1639–1644. PMCID: PMC15544 In vivo transposition of mariner-based
elements in enteric bacteria and mycobacteria Eric J. Rubin, Brian J. Akerley, Veronica N. Novik, David J. Lampe, Robert N. Husson, and John J. Mekalanos Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1645–1650. PMCID: PMC15546 Origin and evolution of the 1918 “Spanish” influenza virus
hemagglutinin gene Ann H. Reid, Thomas G. Fanning, Johan V. Hultin, and Jeffery K. Taubenberger Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1651–1656. PMCID: PMC15547 Neurobiology INAUGURAL ARTICLE by a Recently Elected Academy Member: Brominated 7-hydroxycoumarin-4-ylmethyls: Photolabile protecting
groups with biologically useful cross-sections for two photon
photolysis Toshiaki Furuta, Samuel S.-H. Wang, Jami L. Dantzker, Timothy M. Dore, Wendy J. Bybee, Edward M. Callaway, Winfried Denk, and Roger Y. Tsien Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1193–1200. PMCID: PMC15439 Localization of Niemann–Pick C1 protein in astrocytes:
Implications for neuronal degeneration in Niemann– Pick type
C disease Shutish C. Patel, Sundar Suresh, Ujendra Kumar, C. Y. Hu, Adele Cooney, E. Joan Blanchette-Mackie, Edward B. Neufeld, Ramesh C. Patel, Roscoe O. Brady, Yogesh C. Patel, Peter G. Pentchev, and Wei-Yi Ong Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1657–1662. PMCID: PMC15549 Functional MRI reveals spatially specific attentional modulation
in human primary visual cortex David C. Somers, Anders M. Dale, Adriane E. Seiffert, and Roger B. H. Tootell Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1663–1668. PMCID: PMC15552 Covariation of activity in visual and prefrontal cortex
associated with subjective visual perception Erik D. Lumer and Geraint Rees Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1669–1673. PMCID: PMC15554 Dynamics of tremor-related oscillations in the human globus
pallidus: A single case study José M. Hurtado, Charles M. Gray, Laszlo B. Tamas, and Karen A. Sigvardt Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1674–1679. PMCID: PMC15556 A subcortical pathway to the right amygdala mediating
“unseen” fear J. S. Morris, A. Öhman, and R. J. Dolan Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1680–1685. PMCID: PMC15559 The 70-kDa heat shock cognate protein (Hsc73) gene is enhanced by
ovarian hormones in the ventromedial hypothalamus Christopher J. Krebs, Erich D. Jarvis, and Donald W. Pfaff Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1686–1691. PMCID: PMC15561 Pronounced pharmacologic deficits in M2 muscarinic acetylcholine
receptor knockout mice Jesus Gomeza, Harlan Shannon, Evi Kostenis, Christian Felder, Lu Zhang, Jesse Brodkin, Alexander Grinberg, Hui Sheng, and Jürgen Wess Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1692–1697. PMCID: PMC15563 Increased anxiety and altered responses to anxiolytics in mice
deficient in the 65-kDa isoform of glutamic acid decarboxylase Shera F. Kash, Laurence H. Tecott, Clyde Hodge, and Steinunn Baekkeskov Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1698–1703. PMCID: PMC15565 Control of spine formation by electrical activity in the adult
rat cerebellum Monica Bravin, Laura Morando, Alessandro Vercelli, Ferdinando Rossi, and Piergiorgio Strata Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1704–1709. PMCID: PMC15567 Two serine residues of the glutamate transporter GLT-1 are
crucial for coupling the fluxes of sodium and the neurotransmitter Yumin Zhang and Baruch I. Kanner Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1710–1715. PMCID: PMC15569 Elimination of zinc from synaptic vesicles in the intact mouse
brain by disruption of the ZnT3 gene Toby B. Cole, H. Jürgen Wenzel, Kathy E. Kafer, Philip A. Schwartzkroin, and Richard D. Palmiter Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1716–1721. PMCID: PMC15571 Physiology β-Endorphin blocks luteinizing hormone-releasing hormone
release by inhibiting the nitricoxidergic pathway controlling
its release Alicia G. Faletti, Claudio A. Mastronardi, Alejandro Lomniczi, Adriana Seilicovich, Martha Gimeno, Samuel M. McCann, and Valeria Rettori Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1722–1726. PMCID: PMC15573 Disruption of the β subunit of the epithelial Na+
channel in mice: Hyperkalemia and neonatal death associated with a pseudohypoaldosteronism phenotype Fiona J. McDonald, Baoli Yang, Ron F. Hrstka, Heather A. Drummond, Deirdre E. Tarr, Paul B. McCray, Jr., John B. Stokes, Michael J. Welsh, and Roger A. Williamson Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1727–1731. PMCID: PMC15575 Salt restriction induces pseudohypoaldosteronism type 1 in mice
expressing low levels of the β-subunit of the amiloride-sensitive
epithelial sodium channel Sylvain Pradervand, Pierre M. Barker, Qing Wang, Stephen A. Ernst, Friedrich Beermann, Barbara R. Grubb, Michel Burnier, Andrea Schmidt, Rene J. M. Bindels, John T. Gatzy, Bernard C. Rossier, and Edith Hummler Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1732–1737. PMCID: PMC15577 Plant Biology A protein phosphatase 2C gene,
LjNPP2C1, from Lotus
japonicus induced during root nodule development Philipp Kapranov, Trine Juul Jensen, Carsten Poulsen, Frans J. de
Bruijn, and Krzysztof Szczyglowski Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1738–1743. PMCID: PMC15579 Molecular basis for semidominance of missense mutations in the
XANTHA-H (42-kDa) subunit of magnesium chelatase Andreas Hansson, C. Gamini Kannangara, Diter von Wettstein, and Mats Hansson Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1744–1749. PMCID: PMC15580 Expression of a soybean cytochrome P450 monooxygenase cDNA in
yeast and tobacco enhances the metabolism of phenylurea herbicides Balazs Siminszky, Frederick T. Corbin, Eric R. Ward, Thomas J. Fleischmann, and Ralph E. Dewey Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1750–1755. PMCID: PMC15582 A wound- and systemin-inducible polygalacturonase in tomato
leaves Daniel R. Bergey, Martha Orozco-Cardenas, Daniel S. de Moura, and Clarence A. Ryan Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1756–1760. PMCID: PMC15585 The tomato DWARF enzyme catalyses C-6 oxidation in
brassinosteroid biosynthesis Gerard J. Bishop, Takahito Nomura, Takao Yokota, Kate Harrison, Takahiro Noguchi, Shozo Fujioka, Suguru Takatsuto, Jonathan D. G. Jones, and Yuji Kamiya Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1761–1766. PMCID: PMC15587 An abscisic acid-induced protein kinase, PKABA1, mediates
abscisic acid-suppressed gene expression in barley aleurone layers Aurelio Gómez-Cadenas, Steven D. Verhey, Lynn D. Holappa, Qingxi Shen, Tuan-Hua David Ho, and M. K. Walker-Simmons Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1767–1772. PMCID: PMC15589 Chromosome regions between centromeres and proximal
crossovers are the physical sites of major effect loci for yield in
potato: Genetic analysis employing meiotic mutants J. A. Buso, L. S. Boiteux, G. C. C. Tai, and S. J. Peloquin Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1773–1778. PMCID: PMC15591 Abscisic acid induces oscillations in guard-cell cytosolic
free calcium that involve phosphoinositide-specific phospholipase C Irina Staxén, Christophe Pical, Lucy T. Montgomery, Julie E. Gray, Alistair M. Hetherington, and Martin R. McAinsh Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1779–1784. PMCID: PMC15593 Population Biology Habitat, world geographic range, and embryonic development of
hosts explain the prevalence of avian hematozoa at small spatial
and phylogenetic scales José L. Tella, Guillermo Blanco, Manuela G. Forero, Álvaro Gajón, José A. Donázar, and Fernando Hiraldo Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1785–1789. PMCID: PMC15595 Psychology Localizing the cortical region mediating visual awareness of
object identity Moshe Bar and Irving Biederman Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1790–1793. PMCID: PMC15596 Task-related and item-related brain processes of
memory retrieval Emrah Düzel, Roberto Cabeza, Terence W. Picton, Andrew P. Yonelinas, Henning Scheich, Hans-Jochen Heinze, and Endel Tulving Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1794–1799. PMCID: PMC15598 Social Sciences Anthropology Hypoglossal canal size and hominid speech David DeGusta, W.
Henry Gilbert, and Scott P. Turner Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1800–1804. PMCID: PMC15600 Neandertal nasal structures and upper respiratory tract
“specialization” Robert G. Franciscus Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1805–1809. PMCID: PMC15602 Correction Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1810. PMCID: PMC56017 Corrects: D. Gachotte, et al. Characterization of the Saccharomyces cerevisiae ERG26 gene encoding the C-3 sterol dehydrogenase (C-4 decarboxylase) involved in sterol biosynthesis. Proc Natl Acad Sci U S A. 1998 November 10; 95(23): 13794–13799. Retraction Proc Natl Acad Sci U S A. 1999 February 16; 96(4): 1810. PMCID: PMC56018 Retracts: S Ruetz, et al. The pfmdr1 gene of Plasmodium falciparum confers cellular resistance to antimalarial drugs in yeast cells. Proc Natl Acad Sci U S A. 1996 September 3; 93(18): 9942–9947. |