| | This journal provides immediate access to some articles. Commentaries Tet B or not tet B: Advances in tetracycline-inducible gene expression Helen M. Blau and Fabio M. V. Rossi PMCID: PMC33520 Disease transmission dynamics and the evolution of antibiotic
resistance in hospitals and communal settings Simon A. Levin and Viggo Andreasen PMCID: PMC33521 Xenotropism: The elusive viral receptor finally uncovered Jay A. Levy PMCID: PMC33522 Biological Sciences Biochemistry Niemann-Pick C1 protein: Obligatory roles for N-terminal domains and lysosomal targeting in cholesterol mobilization Hidemichi Watari, E. Joan Blanchette-Mackie, Nancy K. Dwyer, Jane M. Glick, Shutish Patel, Edward B. Neufeld, Roscoe O. Brady, Peter G. Pentchev, and Jerome F. Strauss, III PMCID: PMC15306 INAUGURAL ARTICLE by a Recently Elected Academy Member: Origins of DNA-binding specificity: Role of protein contacts with the DNA backbone Joel F. Schildbach, A. Wali Karzai, Brigitte E. Raumann, and Robert T. Sauer PMCID: PMC15307 Trimeric domain-swapped barnase Ingrid Zegers, Joeri Deswarte, and Lode Wyns PMCID: PMC15308 Three-dimensional structure of phosphoenolpyruvate carboxylase: A proposed mechanism for allosteric inhibition Yasushi Kai, Hiroyoshi Matsumura, Tsuyoshi Inoue, Kazutoyo Terada, Yoshitaka Nagara, Takeo Yoshinaga, Akio Kihara, Kennji Tsumura, and Katsura Izui PMCID: PMC15309 Xenopus laevis sperm receptor gp69/64 glycoprotein is a homolog of the mammalian sperm receptor ZP2 Jingdong Tian, Hui Gong, and William J. Lennarz PMCID: PMC15310 Levels of major selenoproteins in T cells decrease during HIV infection and low molecular mass selenium compounds increase Vadim N. Gladyshev, Thressa C. Stadtman, Dolph L. Hatfield, and Kuan-Teh Jeang PMCID: PMC15311 Structure of the ternary complex of human 17β-hydroxysteroid dehydrogenase type 1 with 3-hydroxyestra-1,3,5,7-tetraen-17-one (equilin) and NADP+ Mark W. Sawicki, Mary Erman, Terhi Puranen, Pirkko Vihko, and Debashis Ghosh PMCID: PMC15312 Mitochondrial disease in superoxide dismutase 2 mutant mice Simon Melov, Pinar Coskun, Manisha Patel, Robbyn Tuinstra, Barbara Cottrell, Albert S. Jun, Tomsz H. Zastawny, Miral Dizdaroglu, Stephen I. Goodman, Ting-Ting Huang, Henry Miziorko, Charles J. Epstein, and Douglas C. Wallace PMCID: PMC15313 U1 small nuclear RNA and spliceosomal introns in Euglena gracilis David G. Breckenridge, Yoh-ichi Watanabe, Spencer J. Greenwood, Michael W. Gray, and Murray N. Schnare PMCID: PMC15314 The specificity of interaction of archaeal transducers with their cognate sensory rhodopsins is determined by their transmembrane helices Xue-Nong Zhang, Jingya Zhu, and John L. Spudich PMCID: PMC15315 TOXCAT: A measure of transmembrane helix association in a biological membrane William P. Russ and Donald M. Engelman PMCID: PMC15316 The C-terminal domain of the regulatory protein NOVH is sufficient to promote interaction with fibulin 1C: A clue for a role of NOVH in cell-adhesion signaling Bernard Perbal, Cécile Martinerie, Richard Sainson, Michel Werner, Bin He, and Bernard Roizman PMCID: PMC15317 Induced fit of a peptide loop of methionyl-tRNA formyltransferase triggered by the initiator tRNA substrate Vaidyanathan Ramesh, Christine Mayer, Michael R. Dyson, Sadanand Gite, and Uttam L. RajBhandary PMCID: PMC15318 Similarity in the catalysis of DNA breakage and rejoining by type IA and IIA DNA topoisomerases Qiyong Liu and James C. Wang PMCID: PMC15319 The minimal gene set member msrA, encoding peptide methionine sulfoxide reductase, is a virulence determinant of the plant pathogen Erwinia chrysanthemi Mohammed El Hassouni, Jean Pierre Chambost, Dominique Expert, Frederique Van Gijsegem, and Frederic Barras PMCID: PMC15320 Biophysics Single-molecule fluorescence spectroscopy of enzyme conformational dynamics and cleavage mechanism Taekjip Ha, Alice Y. Ting, Joy Liang, W. Brett Caldwell, Ashok A. Deniz, Daniel S. Chemla, Peter G. Schultz, and Shimon Weiss PMCID: PMC15321 Enhanced rate of intramolecular electron transfer in an engineered purple CuA azurin Ole Farver, Yi Lu, Majorie C. Ang, and Israel Pecht PMCID: PMC15322 α-Helix nucleation by a calcium-binding peptide loop Monika Siedlecka, Grażyna Goch, Andrzej Ejchart, Heinrich Sticht, and Andrzej Bierzy  ski PMCID: PMC15323 Cell Biology SEM1, a homologue of the split hand/split foot malformation candidate gene Dss1, regulates exocytosis and pseudohyphal differentiation in yeast Jussi Jäntti, Johanna Lahdenranta, Vesa M. Olkkonen, Hans Söderlund, and Sirkka Keränen PMCID: PMC15324 Expression cloning of LDLB, a gene essential for normal Golgi function and assembly of the ldlCp complex Jon E. Chatterton, David Hirsch, John J. Schwartz, Perry E. Bickel, Robert D. Rosenberg, Harvey F. Lodish, and Monty Krieger PMCID: PMC15325 Dimensional and mechanical dynamics of active and stable edges in motile fibroblasts investigated by using atomic force microscopy Christian Rotsch, Ken Jacobson, and Manfred Radmacher PMCID: PMC15326 Cloning and characterization of a cell surface receptor for xenotropic and polytropic murine leukemia viruses Chetankumar S. Tailor, Ali Nouri, Chun G. Lee, Christine Kozak, and David Kabat PMCID: PMC15327 The nuclear matrix prepared by amine modification Katherine M. Wan, Jeffrey A. Nickerson, Gabriela Krockmalnic, and Sheldon Penman PMCID: PMC15328 Model of maltose-binding protein/chemoreceptor complex supports intrasubunit signaling mechanism Yinghua Zhang, Paul J. Gardina, Ann S. Kuebler, Hui S. Kang, Jon A. Christopher, and Michael D. Manson PMCID: PMC15329 Multiple and diverse forms of regulated exocytosis in wild-type and defective PC12 cells Haruo Kasai, Takuya Kishimoto, Ting-Ting Liu, Yasushi Miyashita, Paola Podini, Fabio Grohovaz, and Jacopo Meldolesi PMCID: PMC15330 Developmental Biology FOG-2: A novel GATA-family cofactor related to multitype zinc-finger proteins Friend of GATA-1 and U-shaped Sergei G. Tevosian, Anne E. Deconinck, Alan B. Cantor, Heather I. Rieff, Yuko Fujiwara, Gabriel Corfas, and Stuart H. Orkin PMCID: PMC15331 Molecular cloning of FOG-2: A modulator of transcription factor GATA-4 in cardiomyocytes Eric C. Svensson, Rachel L. Tufts, Christine E. Polk, and Jeffrey M. Leiden PMCID: PMC15332 Metamorphosis is inhibited in transgenic Xenopus laevis tadpoles that overexpress type III deiodinase Haochu Huang, Nicholas Marsh-Armstrong, and Donald D. Brown PMCID: PMC15333 sqv mutants of Caenorhabditis elegans are defective in vulval epithelial invagination Tory Herman, Erika Hartwieg, and H. Robert Horvitz PMCID: PMC15334 Three proteins involved in Caenorhabditis elegans vulval invagination are similar to components of a glycosylation pathway Tory Herman and H. Robert Horvitz PMCID: PMC15335 Ecology Perception of solar UVB radiation by phytophagous insects: Behavioral responses and ecosystem implications Carlos A. Mazza, Jorge Zavala, Ana L. Scopel, and Carlos L. Ballaré PMCID: PMC15336 Interspecific and intraspecific competition as causes of direct and delayed density dependence in a fluctuating vole population Thomas F. Hansen, Nils C. Stenseth, Heikki Henttonen, and Johan Tast PMCID: PMC15337 Evolution Species realities and numbers in sexual vertebrates: Perspectives from an asexually transmitted genome John C. Avise and DeEtte Walker PMCID: PMC15338 Genetics Ectopic expression of E47 or E12 promotes the death of E2A-deficient lymphomas Isaac Engel and Cornelis Murre PMCID: PMC15339 Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma protein-mediated G1 arrest after γ-irradiation James Brugarolas, Ken Moberg, Scott D. Boyd, Yoichi Taya, Tyler Jacks, and Jacqueline A. Lees PMCID: PMC15340 Progressive juvenile-onset punctate cataracts caused by mutation of the γD-crystallin gene Dietrich A. Stephan, Elizabeth Gillanders, Deborah Vanderveen, Diana Freas-Lutz, Graeme Wistow, Andreas D. Baxevanis, Christiane M. Robbins, Ann Van Auken, Matthew I. Quesenberry, Joan Bailey-Wilson, Suh-Hang Hank Juo, Jeffrey M. Trent, Lois Smith, and Michael J. Brownstein PMCID: PMC15341 Generation of conditional mutants in higher eukaryotes by switching between the expression of two genes Udo Baron, Dirk Schnappinger, Vera Helbl, Manfred Gossen, Wolfgang Hillen, and Hermann Bujard PMCID: PMC15342 Immunology CD48-deficient mice have a pronounced defect in CD4+ T cell activation Jesús González-Cabrero, Catherine J. Wise, Yvette Latchman, Gordon J. Freeman, Arlene H. Sharpe, and Hans Reiser PMCID: PMC15343 T cell antigen receptor-mediated activation of the Ras/mitogen-activated protein kinase pathway controls interleukin 4 receptor function and type-2 helper T cell differentiation Masakatsu Yamashita, Motoko Kimura, Masato Kubo, Chiori Shimizu, Tomio Tada, Roger M. Perlmutter, and Toshinori Nakayama PMCID: PMC15344 Lack of infection in HIV-exposed individuals is associated with a strong CD8+ cell noncytotoxic anti-HIV response Sharon A. Stranford, Joan Skurnick, Donald Louria, Dennis Osmond, Sheng-Yung Chang, John Sninsky, Guido Ferrari, Kent Weinhold, Craig Lindquist, and Jay A. Levy PMCID: PMC15345 Distinct dendritic cell subsets differentially regulate the class of immune response in vivo B. Pulendran, J. L. Smith, G. Caspary, K. Brasel, D. Pettit, E. Maraskovsky, and C. R. Maliszewski PMCID: PMC15346 Identification of a cell protein (FIP-3) as a modulator of NF-κB activity and as a target of an adenovirus inhibitor of tumor necrosis factor α-induced apoptosis Yongan Li, Jian Kang, Joshua Friedman, Leonid Tarassishin, Jianjiang Ye, Andrei Kovalenko, David Wallach, and Marshall S. Horwitz PMCID: PMC15347 Medical Sciences The stretch-activation response may be critical to the proper functioning of the mammalian heart Ramesh Vemuri, Edward B. Lankford, Karl Poetter, Shahin Hassanzadeh, Kazuyo Takeda, Zu-Xi Yu, Victor J. Ferrans, and Neal D. Epstein PMCID: PMC15348 Defective collagen crosslinking in bone, but not in ligament or cartilage, in Bruck syndrome: Indications for a bone-specific telopeptide lysyl hydroxylase on chromosome 17 Ruud A. Bank, Simon P. Robins, Cisca Wijmenga, Liesbeth J. Breslau-Siderius, Alfons F. J. Bardoel, Hans A. Van der Sluijs, Hans E. H. Pruijs, and Johan M. TeKoppele PMCID: PMC15349 Enhancing versus suppressive effects of stress hormones on skin immune function Firdaus S. Dhabhar and Bruce S. McEwen PMCID: PMC15350 Gene therapy to promote thromboresistance: Local overexpression of tissue plasminogen activator to prevent arterial thrombosis in an in vivo rabbit model J. M. Waugh, M. Kattash, J. Li, E. Yuksel, M. D. Kuo, M. Lussier, A. B. Weinfeld, R. Saxena, E. D. Rabinovsky, S. Thung, S. L. C. Woo, and S. M. Shenaq PMCID: PMC15351 The relationship between the volume of antimicrobial consumption in human communities and the frequency of resistance D. J. Austin, K. G. Kristinsson, and R. M. Anderson PMCID: PMC15366 Microbiology Identification of a Vibrio cholerae RTX toxin gene cluster that is tightly linked to the cholera toxin prophage Wei Lin, Karla Jean Fullner, Rebecca Clayton, Jessica A. Sexton, Marc B. Rogers, Kerstin E. Calia, Stephen B. Calderwood, Claire Fraser, and John J. Mekalanos PMCID: PMC15352 Variation in expression of the Haemophilus influenzae HMW adhesins: A prokaryotic system reminiscent of eukaryotes Suzanne Dawid, Stephen J. Barenkamp, and Joseph W. St. Geme, III PMCID: PMC15353 Neurobiology The role of presynaptic activity in monocular deprivation: Comparison of homosynaptic and heterosynaptic mechanisms Brian S. Blais, Harel Z. Shouval, and Leon N. Cooper PMCID: PMC15354 Molecular and functional remodeling of electrogenic membrane of hypothalamic neurons in response to changes in their input M. Tanaka, T. R. Cummins, K. Ishikawa, J. A. Black, Y. Ibata, and S. G. Waxman PMCID: PMC15355 A presynaptic role for the ADP ribosylation factor (ARF)-specific GDP/GTP exchange factor msec7-1 Uri Ashery, Henriette Koch, Volker Scheuss, Nils Brose, and Jens Rettig PMCID: PMC15356 Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses Ji-Ying Song, Konstantin Ichtchenko, Thomas C. Südhof, and Nils Brose PMCID: PMC15357 Spatiotemporal activity patterns of rat cortical neurons predict responses in a conditioned task Alessandro E. P. Villa, Igor V. Tetko, Brian Hyland, and Abdellatif Najem PMCID: PMC15358 Neurotrophins regulate agrin-induced postsynaptic differentiation David G. Wells, Beth A. McKechnie, Samir Kelkar, and Justin R. Fallon PMCID: PMC15359 Glutamate and γ-aminobutyric acid mediate a heterosynaptic depression at mossy fiber synapses in the hippocampus Kaspar E. Vogt and Roger A. Nicoll PMCID: PMC15360 Pharmacology Isometric contraction induces the Ca2+-independent activation of the endothelial nitric oxide synthase Ingrid Fleming, Johann Bauersachs, Andreas Schäfer, Dimitri Scholz, Jan Aldershvile, and Rudi Busse PMCID: PMC15361 Physiology Role of mitochondrial lactate dehydrogenase and lactate oxidation in the intracellular lactate shuttle George A. Brooks, Hervé Dubouchaud, Marcia Brown, James P. Sicurello, and C. Eric Butz PMCID: PMC15362 Plant Biology Unusual carotenoid composition and a new type of xanthophyll cycle in plants Ralph A. Bungard, Alexander V. Ruban, Julian M. Hibberd, Malcolm C. Press, Peter Horton, and Julie D. Scholes PMCID: PMC15363 ARG1 (Altered Response to Gravity) encodes a DnaJ-like protein that potentially interacts with the cytoskeleton John C. Sedbrook, Rujin Chen, and Patrick H. Masson PMCID: PMC15364 Antisense-mediated depletion of a potato lipoxygenase reduces wound induction of proteinase inhibitors and increases weight gain of insect pests Joaquín Royo, José León, Guy Vancanneyt, Juan Pablo Albar, Sabine Rosahl, Félix Ortego, Pedro Castañera, and José J. Sánchez-Serrano PMCID: PMC15365 Population Biology The relationship between the volume of antimicrobial consumption in human communities and the frequency of resistance D. J. Austin, K. G. Kristinsson, and R. M. Anderson PMCID: PMC15366 Social Sciences Anthropology Skeletal and dental morphology supports diphyletic origin of baboons and mandrills John G. Fleagle and W. Scott McGraw PMCID: PMC15367 Corrections Proc Natl Acad Sci U S A. 1999 February 2; 96(3): 1162. PMCID: PMC56003 Corrects: Edward A. Berger, et al. Reconsidering targeted toxins to eliminate HIV infection: You gotta
have HAART. Proc Natl Acad Sci U S A. 1998 September 29; 95(20): 11511–11513. Proc Natl Acad Sci U S A. 1999 February 2; 96(3): 1162. PMCID: PMC56004 Corrects: H Bang, et al. Activation of Ca2+ signaling in neutrophils by the mast cell-released immunophilin FKBP12. Proc Natl Acad Sci U S A. 1995 April 11; 92(8): 3435–3438. Proc Natl Acad Sci U S A. 1999 February 2; 96(3): 1162. PMCID: PMC56005 Corrects: Michael J. Shamblott, et al. Derivation of pluripotent stem cells from cultured human primordial germ cells. Proc Natl Acad Sci U S A. 1998 November 10; 95(23): 13726–13731. |
