pmc logo imageJournal ListSearchpmc logo image
Logo of pnasPNAS Home page.PNAS Editorial BoardPNAS AboutPNAS SubscriptionsPNAS Info for Authors
This journal provides immediate access to some articles.
Other Issues:  previous | next | latest | archive
Volume 99(24);  November 26, 2002
Colloquium Papers
Multiplicity results for the Yamabe problem on Sn
Antonio Ambrosetti
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15252–15256. Published online 2002 October 24. doi: 10.1073/pnas.222494199.
PMCID: PMC137702
Solitary waves and Bohmian mechanics
Alberto Abbondandolo and Vieri Benci
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15257–15261. Published online 2002 October 23. doi: 10.1073/pnas.222494299.
PMCID: PMC137703
On the global Cauchy problem for the nonlinear Schrödinger equation
Jean Bourgain
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15262–15268. Published online 2002 November 13. doi: 10.1073/pnas.222494399.
PMCID: PMC137704
Non-Lipschitz minimizers of smooth uniformly convex functionals
Vladimír Sverák and Xiaodong Yan
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15269–15276. Published online 2002 October 28. doi: 10.1073/pnas.222494699.
PMCID: PMC137705
Crystalline variational methods
Jean E. Taylor
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15277–15280. Published online 2002 November 11. doi: 10.1073/pnas.222494799.
PMCID: PMC137706
Elliptic Yang–Mills equation
Gang Tian
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15281–15286. Published online 2002 November 8. doi: 10.1073/pnas.222494899.
PMCID: PMC137707
Some nonlinear elliptic equations from geometry
YanYan Li
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15287–15290. Published online 2002 November 20. doi: 10.1073/pnas.222494999.
PMCID: PMC137708
Commentaries
Fungus-farming insects: Multiple origins and diverse evolutionary histories
Ulrich G. Mueller and Nicole Gerardo
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15247–15249. Published online 2002 November 18. doi: 10.1073/pnas.242594799.
PMCID: PMC137700
Statistical learning in infants
Gerry T. M. Altmann
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15250–15251. Published online 2002 November 18. doi: 10.1073/pnas.262659399.
PMCID: PMC137701
Physical Sciences
Applied Mathematics
Quantifying predictability in a model with statistical features of the atmosphere
Richard Kleeman, Andrew J. Majda, and Ilya Timofeyev
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15291–15296. Published online 2002 November 12. doi: 10.1073/pnas.192583699.
PMCID: PMC137709
Chemistry
Ultrafast surface hydration dynamics and expression of protein functionality: α-Chymotrypsin
Samir Kumar Pal, Jorge Peon, and Ahmed H. Zewail
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15297–15302. Published online 2002 November 11. doi: 10.1073/pnas.242600399.
PMCID: PMC137710
Are helionitronium trications stable?
Wolfgang Eisfeld and Joseph S. Francisco
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15303–15307. Published online 2002 November 12. doi: 10.1073/pnas.242490299.
PMCID: PMC137711
Peroxone chemistry: Formation of H2O3 and ring-(HO2)(HO3) from O3/H2O2
Xin Xu and William A. Goddard, III
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15308–15312. Published online 2002 November 18. doi: 10.1073/pnas.202596799.
PMCID: PMC137712
Invisible liposomes: Refractive index matching with sucrose enables flow dichroism assessment of peptide orientation in lipid vesicle membrane
Malin Ardhammar, Per Lincoln, and Bengt Nordén
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15313–15317. Published online 2002 November 6. doi: 10.1073/pnas.192583499.
PMCID: PMC137713
Engineering
Gaussian curvature and the equilibrium among bilayer cylinders, spheres, and discs
H.-T. Jung, S. Y. Lee, E. W. Kaler, B. Coldren, and J. A. Zasadzinski
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15318–15322. Published online 2002 November 20. doi: 10.1073/pnas.242374499.
PMCID: PMC137714
Geology
From the Cover:
Low-magnesium calcite produced by coralline algae in seawater of Late Cretaceous composition
Steven M. Stanley, Justin B. Ries, and Lawrence A. Hardie
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15323–15326. Published online 2002 October 24. doi: 10.1073/pnas.232569499.
PMCID: PMC137715
Biological Sciences
Biochemistry
Escherichia coli RecO protein anneals ssDNA complexed with its cognate ssDNA-binding protein: A common step in genetic recombination
Noriko Kantake, Murty V. V. M. Madiraju, Tomohiko Sugiyama, and Stephen C. Kowalczykowski
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15327–15332. Published online 2002 November 18. doi: 10.1073/pnas.252633399.
PMCID: PMC137716
Tissue factor deficiency causes cardiac fibrosis and left ventricular dysfunction
R. Pawlinski, A. Fernandes, B. Kehrle, B. Pedersen, G. Parry, J. Erlich, R. Pyo, D. Gutstein, J. Zhang, F. Castellino, E. Melis, P. Carmeliet, G. Baretton, T. Luther, M. Taubman, E. Rosen, and N. Mackman
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15333–15338. Published online 2002 November 8. doi: 10.1073/pnas.242501899.
PMCID: PMC137717
Early stages of energy transduction by myosin: Roles of Arg in Switch I, of Glu in Switch II, and of the salt-bridge between them
Hirofumi Onishi, Takashi Ohki, Naoki Mochizuki, and Manuel F. Morales
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15339–15344. Published online 2002 November 12. doi: 10.1073/pnas.242604099.
PMCID: PMC137718
Measurement in vivo of proliferation rates of slow turnover cells by 2H2O labeling of the deoxyribose moiety of DNA
R. A. Neese, L. M. Misell, S. Turner, A. Chu, J. Kim, D. Cesar, R. Hoh, F. Antelo, A. Strawford, J. M. McCune, M. Christiansen, and M. K. Hellerstein
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15345–15350. Published online 2002 November 7. doi: 10.1073/pnas.232551499.
PMCID: PMC137719
Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway
Charles E. Dann, III, Richard K. Bruick, and Johann Deisenhofer
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15351–15356. Published online 2002 November 13. doi: 10.1073/pnas.202614999.
PMCID: PMC137720
Structure and function from the circadian clock protein KaiA of Synechococcus elongatus: A potential clock input mechanism
Stanly B. Williams, Ioannis Vakonakis, Susan S. Golden, and Andy C. LiWang
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15357–15362. Published online 2002 November 15. doi: 10.1073/pnas.232517099.
PMCID: PMC137721
Identification in Drosophila melanogaster of the invertebrate G protein-coupled FMRFamide receptor
Tom Meeusen, Inge Mertens, Elke Clynen, Geert Baggerman, Ruthann Nichols, Ronald J. Nachman, Roger Huybrechts, Arnold De Loof, and Liliane Schoofs
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15363–15368. Published online 2002 November 18. doi: 10.1073/pnas.252339599.
PMCID: PMC137722
Crystal structure of a human aminoacyl-tRNA synthetase cytokine
Xiang-Lei Yang, Robert J. Skene, Duncan E. McRee, and Paul Schimmel
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15369–15374. Published online 2002 November 11. doi: 10.1073/pnas.242611799.
PMCID: PMC137723
Bornyl diphosphate synthase: Structure and strategy for carbocation manipulation by a terpenoid cyclase
Douglas A. Whittington, Mitchell L. Wise, Marek Urbansky, Robert M. Coates, Rodney B. Croteau, and David W. Christianson
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15375–15380. Published online 2002 November 13. doi: 10.1073/pnas.232591099.
PMCID: PMC137724
SWI/SNF-dependent long-range remodeling of yeast HIS3 chromatin
Yeonjung Kim and David J. Clark
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15381–15386. Published online 2002 November 13. doi: 10.1073/pnas.242536699.
PMCID: PMC137725
The mechanism of topoisomerase I poisoning by a camptothecin analog
Bart L. Staker, Kathryn Hjerrild, Michael D. Feese, Craig A. Behnke, Alex B. Burgin, Jr., and Lance Stewart
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15387–15392. Published online 2002 November 8. doi: 10.1073/pnas.242259599.
PMCID: PMC137726
Biophysics
Ultrafast surface hydration dynamics and expression of protein functionality: α-Chymotrypsin
Samir Kumar Pal, Jorge Peon, and Ahmed H. Zewail
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15297–15302. Published online 2002 November 11. doi: 10.1073/pnas.242600399.
PMCID: PMC137710
Invisible liposomes: Refractive index matching with sucrose enables flow dichroism assessment of peptide orientation in lipid vesicle membrane
Malin Ardhammar, Per Lincoln, and Bengt Nordén
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15313–15317. Published online 2002 November 6. doi: 10.1073/pnas.192583499.
PMCID: PMC137713
From the Cover:
Mitotic chromosomes are chromatin networks without a mechanically contiguous protein scaffold
Michael G. Poirier and John F. Marko
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15393–15397. Published online 2002 November 18. doi: 10.1073/pnas.232442599.
PMCID: PMC137727
The substrate binding domain of DnaK facilitates slow protein refolding
Naoki Tanaka, Shota Nakao, Hiromasa Wadai, Shoichi Ikeda, Jean Chatellier, and Shigeru Kunugi
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15398–15403. Published online 2002 November 14. doi: 10.1073/pnas.242317099.
PMCID: PMC137728
Control of biochemical reactions through supramolecular RING domain self-assembly
Alex Kentsis, Ronald E. Gordon, and Katherine L. B. Borden
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15404–15409. Published online 2002 November 18. doi: 10.1073/pnas.202608799.
PMCID: PMC137729
Conformational-relaxation models of single-enzyme kinetics
Hans-Philipp Lerch, Alexander S. Mikhailov, and Benno Hess
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15410–15415. Published online 2002 November 12. doi: 10.1073/pnas.232376799.
PMCID: PMC137730
Circular dichroism spectra of short, fixed-nucleus alanine helices
Der-Hang Chin, Robert W. Woody, Carol A. Rohl, and Robert L. Baldwin
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15416–15421. Published online 2002 November 11. doi: 10.1073/pnas.232591399.
PMCID: PMC137731
Cell Biology
Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI
Thomas J. F. Nieland, Marsha Penman, Limor Dori, Monty Krieger, and Tomas Kirchhausen
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15422–15427. Published online 2002 November 18. doi: 10.1073/pnas.222421399.
PMCID: PMC137732
Chemical chaperones increase the cellular activity of N370S β-glucosidase: A therapeutic strategy for Gaucher disease
Anu R. Sawkar, Wei-Chieh Cheng, Ernest Beutler, Chi-Huey Wong, William E. Balch, and Jeffery W. Kelly
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15428–15433. Published online 2002 November 14. doi: 10.1073/pnas.192582899.
PMCID: PMC137733
Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins
Karina Barseguian, Bart Lutterbach, Scott W. Hiebert, Jeffrey Nickerson, Jane B. Lian, Janet L. Stein, Andre J. van Wijnen, and Gary S. Stein
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15434–15439. Published online 2002 November 11. doi: 10.1073/pnas.242588499.
PMCID: PMC137734
Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A
Laurie E. Littlepage, Hua Wu, Thorkell Andresson, Julia K. Deanehan, Laufey T. Amundadottir, and Joan V. Ruderman
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15440–15445. Published online 2002 November 6. doi: 10.1073/pnas.202606599.
PMCID: PMC137735
Developmental Biology
Bombyxin is a growth factor for wing imaginal disks in Lepidoptera
H. Frederik Nijhout and Laura W. Grunert
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15446–15450. Published online 2002 November 12. doi: 10.1073/pnas.242548399.
PMCID: PMC137736
Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells
Thaddeus S. Stappenbeck, Lora V. Hooper, and Jeffrey I. Gordon
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15451–15455. Published online 2002 November 13. doi: 10.1073/pnas.202604299.
PMCID: PMC137737
Pineal expression-promoting element (PIPE), a cis-acting element, directs pineal-specific gene expression in zebrafish
Yoichi Asaoka, Hiroaki Mano, Daisuke Kojima, and Yoshitaka Fukada
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15456–15461. Published online 2002 November 18. doi: 10.1073/pnas.232444199.
PMCID: PMC137738
Role of the thyroid-stimulating hormone receptor signaling in development and differentiation of the thyroid gland
M. P. Postiglione, R. Parlato, A. Rodriguez-Mallon, A. Rosica, P. Mithbaokar, M. Maresca, R. C. Marians, T. F. Davies, M. S. Zannini, M. De Felice, and R. Di Lauro
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15462–15467. Published online 2002 November 13. doi: 10.1073/pnas.242328999.
PMCID: PMC137739
Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cells
Chang-Zheng Chen, Min Li, David de Graaf, Stefano Monti, Berthold Göttgens, Maria-Jose Sanchez, Eric S. Lander, Todd R. Golub, Anthony R. Green, and Harvey F. Lodish
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15468–15473. Published online 2002 November 15. doi: 10.1073/pnas.202614899.
PMCID: PMC137740
Activin A induces craniofacial cartilage from undifferentiated Xenopus ectoderm in vitro
Miho Furue, Yasufumi Myoishi, Yasuto Fukui, Takashi Ariizumi, Tetsuji Okamoto, and Makoto Asashima
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15474–15479. Published online 2002 November 7. doi: 10.1073/pnas.242597399.
PMCID: PMC137741
Two isoforms of the Notch antagonist Hairless are produced by differential translation initiation
Dieter Maier, Anja C. Nagel, and Anette Preiss
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15480–15485. Published online 2002 November 6. doi: 10.1073/pnas.242596699.
PMCID: PMC137742
Ecology
Altered host plant volatiles are proxies for sex pheromones in the gall wasp Antistrophus rufus
John F. Tooker, Wilfried A. Koenig, and Lawrence M. Hanks
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15486–15491. Published online 2002 November 18. doi: 10.1073/pnas.252626799.
PMCID: PMC137743
A computational method for resequencing long DNA targets by universal oligonucleotide arrays
Itsik Pe'er, Naama Arbili, and Ron Shamir
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15492–15496. Published online 2002 November 12. doi: 10.1073/pnas.232278299.
PMCID: PMC137744
Linking climate change and biological invasions: Ocean warming facilitates nonindigenous species invasions
John J. Stachowicz, Jeffrey R. Terwin, Robert B. Whitlatch, and Richard W. Osman
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15497–15500. Published online 2002 November 6. doi: 10.1073/pnas.242437499.
PMCID: PMC137745
Evolution
The effect of selection on a long wavelength-sensitive (LWS) opsin gene of Lake Victoria cichlid fishes
Yohey Terai, Werner E. Mayer, Jan Klein, Herbert Tichy, and Norihiro Okada
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15501–15506. Published online 2002 November 15. doi: 10.1073/pnas.232561099.
PMCID: PMC137746
From the Cover:
The single, ancient origin of chromist plastids
Hwan Su Yoon, Jeremiah D. Hackett, Gabriele Pinto, and Debashish Bhattacharya
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15507–15512. Published online 2002 November 15. doi: 10.1073/pnas.242379899.
PMCID: PMC137747
The signal of ancient introns is obscured by intron density and homolog number
Scott William Roy, Alexei Fedorov, and Walter Gilbert
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15513–15517. Published online 2002 November 13. doi: 10.1073/pnas.242600199.
PMCID: PMC137748
A general population genetic theory for the evolution of developmental interactions
Sean H. Rice
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15518–15523. Published online 2002 November 18. doi: 10.1073/pnas.202620999.
PMCID: PMC137749
Genetics
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
George Adrian Calin, Calin Dan Dumitru, Masayoshi Shimizu, Roberta Bichi, Simona Zupo, Evan Noch, Hansjuerg Aldler, Sashi Rattan, Michael Keating, Kanti Rai, Laura Rassenti, Thomas Kipps, Massimo Negrini, Florencia Bullrich, and Carlo M. Croce
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15524–15529. Published online 2002 November 14. doi: 10.1073/pnas.242606799.
PMCID: PMC137750
Parallel phenotypic analysis of sporulation and postgermination growth in Saccharomyces cerevisiae
Adam M. Deutschbauer, Roy M. Williams, Angela M. Chu, and Ronald W. Davis
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15530–15535. Published online 2002 November 13. doi: 10.1073/pnas.202604399.
PMCID: PMC137751
Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain
Matthew Tudor, Schahram Akbarian, Richard Z. Chen, and Rudolf Jaenisch
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15536–15541. Published online 2002 November 13. doi: 10.1073/pnas.242566899.
PMCID: PMC137752
An allelic series of mutations in Smad2 and Smad4 identified in a genotype-based screen of N-ethyl-N- nitrosourea-mutagenized mouse embryonic stem cells
Jay L. Vivian, Yijing Chen, Della Yee, Elizabeth Schneider, and Terry Magnuson
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15542–15547. Published online 2002 November 13. doi: 10.1073/pnas.242474199.
PMCID: PMC137753
Polκ protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene
Tomoo Ogi, Yoichi Shinkai, Kiyoji Tanaka, and Haruo Ohmori
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15548–15553. Published online 2002 November 13. doi: 10.1073/pnas.222377899.
PMCID: PMC137754
Identification of the gene responsible for the cblA complementation group of vitamin B12-responsive methylmalonic acidemia based on analysis of prokaryotic gene arrangements
C. Melissa Dobson, Timothy Wai, Daniel Leclerc, Aaron Wilson, Xuchu Wu, Carole Doré, Thomas Hudson, David S. Rosenblatt, and Roy A. Gravel
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15554–15559. Published online 2002 November 15. doi: 10.1073/pnas.242614799.
PMCID: PMC137755
High incidence of epithelial cancers in mice deficient for DNA polymerase δ proofreading
Robert E. Goldsby, Laura E. Hays, Xin Chen, Elise A. Olmsted, William B. Slayton, Gerry J. Spangrude, and Bradley D. Preston
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15560–15565. Published online 2002 November 12. doi: 10.1073/pnas.232340999.
PMCID: PMC137756
Immunology
RAG-dependent peripheral T cell receptor diversification in CD8+ T lymphocytes
Pau Serra, Abdelaziz Amrani, Bingye Han, Jun Yamanouchi, Shari J. Thiessen, and Pere Santamaria
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15566–15571. Published online 2002 November 13. doi: 10.1073/pnas.242321099.
PMCID: PMC137757
In vivo dynamics of T cell activation, proliferation, and death in HIV-1 infection: Why are CD4+ but not CD8+ T cells depleted?
Ruy M. Ribeiro, Hiroshi Mohri, David D. Ho, and Alan S. Perelson
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15572–15577. Published online 2002 November 14. doi: 10.1073/pnas.242358099.
PMCID: PMC137758
Medical Sciences
Involvement of estrogen receptor β in terminal differentiation of mammary gland epithelium
Carola Förster, Sari Mäkela, Anni Wärri, Silke Kietz, David Becker, Kjell Hultenby, Margaret Warner, and Jan-Åke Gustafsson
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15578–15583. Published online 2002 November 18. doi: 10.1073/pnas.192561299.
PMCID: PMC137759
A comparison of the molecular clock of hepatitis C virus in the United States and Japan predicts that hepatocellular carcinoma incidence in the United States will increase over the next two decades
Yasuhito Tanaka, Kousuke Hanada, Masashi Mizokami, Anthony E. T. Yeo, J. Wai-Kuo Shih, Takashi Gojobori, and Harvey J. Alter
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15584–15589. Published online 2002 November 18. doi: 10.1073/pnas.242608099.
PMCID: PMC137760
Cell surface CCR5 density determines the postentry efficiency of R5 HIV-1 infection
Yea-Lih Lin, Clément Mettling, Pierre Portales, Jacques Reynes, Jacques Clot, and Pierre Corbeau
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15590–15595. Published online 2002 November 14. doi: 10.1073/pnas.242134499.
PMCID: PMC137761
Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy
Helen Vlassara, Weijing Cai, Jill Crandall, Teresia Goldberg, Robert Oberstein, Veronique Dardaine, Melpomeni Peppa, and Elliot J. Rayfield
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15596–15601. Published online 2002 November 12. doi: 10.1073/pnas.242407999.
PMCID: PMC137762
The hemochromatosis protein HFE inhibits iron export from macrophages
Hal Drakesmith, Emma Sweetland, Lisa Schimanski, Jon Edwards, Diana Cowley, Mubeen Ashraf, Judy Bastin, and Alain R. M. Townsend
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15602–15607. Published online 2002 November 12. doi: 10.1073/pnas.242614699.
PMCID: PMC137763
Noninvasive imaging of protein–protein interactions in living subjects by using reporter protein complementation and reconstitution strategies
R. Paulmurugan, Y. Umezawa, and S. S. Gambhir
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15608–15613. Published online 2002 November 18. doi: 10.1073/pnas.242594299.
PMCID: PMC137764
Targeting the Mycobacterium tuberculosis 30/32-kDa mycolyl transferase complex as a therapeutic strategy against tuberculosis: Proof of principle by using antisense technology
Günter Harth, Marcus A. Horwitz, David Tabatadze, and Paul C. Zamecnik
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15614–15619. Published online 2002 November 11. doi: 10.1073/pnas.242612299.
PMCID: PMC137765
Neuroprotective autoimmunity: Naturally occurring CD4+CD25+ regulatory T cells suppress the ability to withstand injury to the central nervous system
Jonathan Kipnis, Tal Mizrahi, Ehud Hauben, Iftach Shaked, Ethan Shevach, and Michal Schwartz
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15620–15625. Published online 2002 November 12. doi: 10.1073/pnas.232565399.
PMCID: PMC137766
A genomic-scale view of the cAMP response element-enhancer decoy: A tumor target-based genetic tool
Yee Sook Cho, Meyoung-Kon Kim, Chris Cheadle, Catherine Neary, Yun Gyu Park, Kevin G. Becker, and Yoon S. Cho-Chung
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15626–15631. Published online 2002 November 18. doi: 10.1073/pnas.242617799.
PMCID: PMC137767
Gene expression profiling of isogenic cells with different TP53 gene dosage reveals numerous genes that are affected by TP53 dosage and identifies CSPG2 as a direct target of p53
Heejei Yoon, Sandya Liyanarachchi, Fred A. Wright, Ramana Davuluri, Janet C. Lockman, Albert de la Chapelle, and Natalia S. Pellegata
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15632–15637. Published online 2002 November 15. doi: 10.1073/pnas.242597299.
PMCID: PMC137768
Measurements of endothelial cell-to-cell and cell-to-substrate gaps and micromechanical properties of endothelial cells during monocyte adhesion
Noriyuki Kataoka, Kanso Iwaki, Ken Hashimoto, Seiichi Mochizuki, Yasuo Ogasawara, Masaaki Sato, Katsuhiko Tsujioka, and Fumihiko Kajiya
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15638–15643. Published online 2002 November 14. doi: 10.1073/pnas.242590799.
PMCID: PMC137769
Progesterone receptor knockout mice have an improved glucose homeostasis secondary to β-cell proliferation
Frédéric Picard, Mitsuhiro Wanatabe, Kristina Schoonjans, John Lydon, Bert W. O'Malley, and Johan Auwerx
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15644–15648. Published online 2002 November 15. doi: 10.1073/pnas.202612199.
PMCID: PMC137770
The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria
Johan W. Jonker, Marije Buitelaar, Els Wagenaar, Martin A. van der Valk, George L. Scheffer, Rik J. Scheper, Torsten Plösch, Folkert Kuipers, Ronald P. J. Oude Elferink, Hilde Rosing, Jos H. Beijnen, and Alfred H. Schinkel
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15649–15654. Published online 2002 November 12. doi: 10.1073/pnas.202607599.
PMCID: PMC137771
Microbiology
Infection of a human hepatoma cell line by hepatitis B virus
Philippe Gripon, Sylvie Rumin, Stephan Urban, Jacques Le Seyec, Denise Glaise, Isabelle Cannie, Claire Guyomard, Josette Lucas, Christian Trepo, and Christiane Guguen-Guillouzo
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15655–15660. Published online 2002 November 13. doi: 10.1073/pnas.232137699.
PMCID: PMC137772
Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease
Robert Thimme, Jens Bukh, Hans Christian Spangenberg, Stefan Wieland, Janell Pemberton, Carola Steiger, Sugantha Govindarajan, Robert H. Purcell, and Francis V. Chisari
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15661–15668. Published online 2002 November 19. doi: 10.1073/pnas.202608299.
PMCID: PMC137773
Genomic analysis of the host response to hepatitis C virus infection
Andrew I. Su, John P. Pezacki, Lisa Wodicka, Amy D. Brideau, Lubica Supekova, Robert Thimme, Stefan Wieland, Jens Bukh, Robert H. Purcell, Peter G. Schultz, and Francis V. Chisari
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15669–15674. Published online 2002 November 19. doi: 10.1073/pnas.202608199.
PMCID: PMC137774
Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis
Eleftherios Mylonakis, Frederick M. Ausubel, John R. Perfect, Joseph Heitman, and Stephen B. Calderwood
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15675–15680. Published online 2002 November 15. doi: 10.1073/pnas.232568599.
PMCID: PMC137775
Cultivating the uncultured
Karsten Zengler, Gerardo Toledo, Michael Rappé, James Elkins, Eric J. Mathur, Jay M. Short, and Martin Keller
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15681–15686. Published online 2002 November 18. doi: 10.1073/pnas.252630999.
PMCID: PMC137776
Microarray-based detection and genotyping of viral pathogens
David Wang, Laurent Coscoy, Maxine Zylberberg, Pedro C. Avila, Homer A. Boushey, Don Ganem, and Joseph L. DeRisi
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15687–15692. Published online 2002 November 12. doi: 10.1073/pnas.242579699.
PMCID: PMC137777
Membrane localization of MinD is mediated by a C-terminal motif that is conserved across eubacteria, archaea, and chloroplasts
Tim H. Szeto, Susan L. Rowland, Lawrence I. Rothfield, and Glenn F. King
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15693–15698. Published online 2002 November 7. doi: 10.1073/pnas.232590599.
PMCID: PMC137778
A simple alfalfa seedling infection model for Pseudomonas aeruginosa strains associated with cystic fibrosis shows AlgT (sigma-22) and RhlR contribute to pathogenesis
Laura Silo-Suh, Sang-Jin Suh, Pamela A. Sokol, and Dennis E. Ohman
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15699–15704. Published online 2002 November 8. doi: 10.1073/pnas.242343999.
PMCID: PMC137779
Host–pathogen interactions: Host resistance factor Nramp1 up-regulates the expression of Salmonella pathogenicity island-2 virulence genes
Michelle L. Zaharik, Bruce A. Vallance, José L. Puente, Philippe Gros, and B. Brett Finlay
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15705–15710. Published online 2002 November 19. doi: 10.1073/pnas.252415599.
PMCID: PMC137780
The analysis of the intramacrophagic virulome of Brucella suis deciphers the environment encountered by the pathogen inside the macrophage host cell
Stephan Köhler, Vincent Foulongne, Safia Ouahrani-Bettache, Gisèle Bourg, Jacques Teyssier, Michel Ramuz, and Jean-Pierre Liautard
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15711–15716. Published online 2002 November 18. doi: 10.1073/pnas.232454299.
PMCID: PMC137781
Neuroscience
An exchanger-like protein underlies the large Mg2+ current in Paramecium
W. John Haynes, Ching Kung, Yoshiro Saimi, and Robin R. Preston
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15717–15722. Published online 2002 November 6. doi: 10.1073/pnas.242603999.
PMCID: PMC137782
Neurovestibular modulation of circadian and homeostatic regulation: Vestibulohypothalamic connection?
Patrick M. Fuller, Timothy A. Jones, Sherri M. Jones, and Charles A. Fuller
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15723–15728. Published online 2002 November 14. doi: 10.1073/pnas.242251499.
PMCID: PMC137783
Disrupted synaptic development in the hypoxic newborn brain
Sheila M. Curristin, Anjun Cao, William B. Stewart, Heping Zhang, Joseph A. Madri, Jon S. Morrow, and Laura R. Ment
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15729–15734. Published online 2002 November 15. doi: 10.1073/pnas.232568799.
PMCID: PMC137784
Optical imaging reveals retinotopic organization of dorsal V3 in New World owl monkeys
David C. Lyon, Xiangmin Xu, Vivien A. Casagrande, James D. Stefansic, Daniel Shima, and Jon H. Kaas
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15735–15742. Published online 2002 November 19. doi: 10.1073/pnas.242600699.
PMCID: PMC137785
Reorganization of the cochleotopic map in the bat's auditory system by inhibition
Zhongju Xiao and Nobuo Suga
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15743–15748. Published online 2002 November 5. doi: 10.1073/pnas.242606699.
PMCID: PMC137786
Intracerebroventricular corticotropin-releasing factor increases limbic glucose metabolism and has social context-dependent behavioral effects in nonhuman primates
Elissa M. Strome, G. H. Trevor Wheler, J. Dee Higley, D. Lynn Loriaux, Stephen J. Suomi, and Doris J. Doudet
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15749–15754. Published online 2002 November 18. doi: 10.1073/pnas.232480899.
PMCID: PMC137787
Auditory looming perception in rhesus monkeys
Asif A. Ghazanfar, John G. Neuhoff, and Nikos K. Logothetis
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15755–15757. Published online 2002 November 12. doi: 10.1073/pnas.242469699.
PMCID: PMC137788
Increased rates of cerebral glucose metabolism in a mouse model of fragile X mental retardation
Mei Qin, Julia Kang, and Carolyn Beebe Smith
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15758–15763. Published online 2002 November 11. doi: 10.1073/pnas.242377399.
PMCID: PMC137789
Fast synaptic transmission between striatal spiny projection neurons
Uwe Czubayko and Dietmar Plenz
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15764–15769. Published online 2002 November 18. doi: 10.1073/pnas.242428599.
PMCID: PMC137790
Pharmacology
NCX-1015, a nitric-oxide derivative of prednisolone, enhances regulatory T cells in the lamina propria and protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice
Stefano Fiorucci, Elisabetta Antonelli, Eleonora Distrutti, Piero Del Soldato, Roderick J. Flower, Mark J. Paul Clark, Antonio Morelli, Mauro Perretti, and Louis J. Ignarro
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15770–15775. Published online 2002 November 11. doi: 10.1073/pnas.232583599.
PMCID: PMC137791
Physiology
Defining thyrotropin-dependent and -independent steps of thyroid hormone synthesis by using thyrotropin receptor-null mice
R. C. Marians, L. Ng, H. C. Blair, P. Unger, P. N. Graves, and T. F. Davies
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15776–15781. Published online 2002 November 13. doi: 10.1073/pnas.242322099.
PMCID: PMC137792
Kidney-specific chloride channel, OmClC-K, predominantly expressed in the diluting segment of freshwater-adapted tilapia kidney
Hiroaki Miyazaki, Toyoji Kaneko, Shinichi Uchida, Sei Sasaki, and Yoshio Takei
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15782–15787. Published online 2002 November 11. doi: 10.1073/pnas.242611099.
PMCID: PMC137793
Plant Biology
KaiA-stimulated KaiC phosphorylation in circadian timing loops in cyanobacteria
Hideo Iwasaki, Taeko Nishiwaki, Yohko Kitayama, Masato Nakajima, and Takao Kondo
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15788–15793. Published online 2002 October 21. doi: 10.1073/pnas.222467299.
PMCID: PMC137794
Visualization by comprehensive microarray analysis of gene expression programs during transdifferentiation of mesophyll cells into xylem cells
Taku Demura, Gen Tashiro, Gorou Horiguchi, Naoki Kishimoto, Minoru Kubo, Naoko Matsuoka, Atsushi Minami, Miyo Nagata-Hiwatashi, Keiko Nakamura, Yoshimichi Okamura, Naomi Sassa, Shinsuke Suzuki, Junshi Yazaki, Shoshi Kikuchi, and Hiroo Fukuda
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15794–15799. Published online 2002 November 18. doi: 10.1073/pnas.232590499.
PMCID: PMC137795
An Arabidopsis histidine kinase is essential for megagametogenesis
Melissa S. Pischke, Linda G. Jones, Denichiro Otsuga, Donna E. Fernandez, Gary N. Drews, and Michael R. Sussman
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15800–15805. Published online 2002 November 8. doi: 10.1073/pnas.232580499.
PMCID: PMC137796
A chloroplast FKBP interacts with and affects the accumulation of Rieske subunit of cytochrome bf complex
Rajeev Gupta, Ruth M. Mould, Zengyong He, and Sheng Luan
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15806–15811. Published online 2002 November 7. doi: 10.1073/pnas.222550399.
PMCID: PMC137797
Mitogen-activated protein kinase signaling in postgermination arrest of development by abscisic acid
C. Lu, M.-H. Han, A. Guevara-Garcia, and N. V. Fedoroff
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15812–15817. Published online 2002 November 14. doi: 10.1073/pnas.242607499.
PMCID: PMC137798
The systemin precursor gene regulates both defensive and developmental genes in Solanum tuberosum
Javier Narváez-Vásquez and Clarence A. Ryan, Jr.
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15818–15821. Published online 2002 November 8. doi: 10.1073/pnas.232591199.
PMCID: PMC137799
Psychology (Biological Sciences)
From the Cover:
Statistical learning of new visual feature combinations by infants
József Fiser and Richard N. Aslin
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15822–15826. Published online 2002 November 12. doi: 10.1073/pnas.232472899.
PMCID: PMC137800
Social Sciences
Economic Sciences
Testing neoclassical competitive market theory in the field
John A. List
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15827–15830. Published online 2002 November 13. doi: 10.1073/pnas.202602999.
PMCID: PMC137801
Corrections
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15831. Published online 2002 November 13. doi: 10.1073/pnas.242625699.
PMCID: PMC137696
Corrects: Carol M. Kiekhaefer, et al. Hematopoietic-specific activators establish an overlapping pattern of histone acetylation and methylation within a mammalian chromatin domain. Proc Natl Acad Sci U S A. 2002 October 29; 99(22): 14309–14314.
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15831. Published online 2002 November 11. doi: 10.1073/pnas.252628999.
PMCID: PMC137697
Corrects: Linh Hoang, et al. Cytochrome c folding pathway: Kinetic native-state hydrogen exchange. Proc Natl Acad Sci U S A. 2002 September 17; 99(19): 12173–12178.
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15831. Published online 2002 November 18. doi: 10.1073/pnas.222515899.
PMCID: PMC137698
Corrects: Daniel J. Battle, et al. From the Cover:
Specificity of RNA–RNA helix recognition.
Proc Natl Acad Sci U S A. 2002 September 3; 99(18): 11676–11681.
Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15831. Published online 2002 November 12. doi: 10.1073/pnas.232531999.
PMCID: PMC137699
Corrects: Andreas Heise, et al. Two immediate-early pathogen-responsive members of the AtCMPG gene family in Arabidopsis thaliana and the W-box-containing elicitor-response element of AtCMPG1. Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9049–9054.
Other Issues:  previous | next | latest | archive