| | This journal provides immediate access to some articles. Commentaries Varitint-waddler: A double whammy for hearing Karen P. Steel PMCID: PMC133623 Shedding light on an underground problem Jeanne Harris PMCID: PMC137465 New insights and new approaches toward the study of age-related macular degeneration Dean Bok PMCID: PMC137466 Head to head with Boas: Did he err on the plasticity of head form? Ralph L. Holloway PMCID: PMC137467 Perspective Explaining the Pleistocene megafaunal extinctions: Models, chronologies, and assumptions Barry W. Brook and David M. J. S. Bowman PMCID: PMC137468 Physical Sciences Applied Mathematics INAUGURAL ARTICLE by a Recently Elected Academy Member: Finding important sites in protein sequences Peter J. Bickel, Katherina J. Kechris, Philip C. Spector, Gary J. Wedemayer, and Alexander N. Glazer PMCID: PMC137493 Chemistry Prebiotic synthesis from CO atmospheres: Implications for the origins of life Shin Miyakawa, Hiroto Yamanashi, Kensei Kobayashi, H. James Cleaves, and Stanley L. Miller PMCID: PMC137469 Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells Mini Thomas and Alexander M. Klibanov PMCID: PMC137472 Physics No time loophole in Bell's theorem: The Hess–Philipp model is nonlocal R. D. Gill, G. Weihs, A. Zeilinger, and M. Żukowski PMCID: PMC137470 Biological Sciences Anthropology-BS A reassessment of human cranial plasticity: Boas revisited Corey S. Sparks and Richard L. Jantz PMCID: PMC137471 Applied Biological Sciences Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells Mini Thomas and Alexander M. Klibanov PMCID: PMC137472 S-layer-streptavidin fusion proteins as template for nanopatterned molecular arrays Dieter Moll, Carina Huber, Birgit Schlegel, Dietmar Pum, Uwe B. Sleytr, and Margit Sára PMCID: PMC137473 A cell-free protein synthesis system for high-throughput proteomics Tatsuya Sawasaki, Tomio Ogasawara, Ryo Morishita, and Yaeta Endo PMCID: PMC137474 Biochemistry Resistance to the macrolide antibiotic tylosin is conferred by single methylations at 23S rRNA nucleotides G748 and A2058 acting in synergy Mingfu Liu and Stephen Douthwaite PMCID: PMC137475 Short constrained peptides that inhibit HIV-1 entry Samuel K. Sia, Peter A. Carr, Andrea G. Cochran, Vladimir N. Malashkevich, and Peter S. Kim PMCID: PMC137476 The A14–A43 heterodimer subunit in yeast RNA pol I and their relationship to Rpb4–Rpb7 pol II subunits Gérald Peyroche, Erwann Levillain, Magali Siaut, Isabelle Callebaut, Patrick Schultz, André Sentenac, Michel Riva, and Christophe Carles PMCID: PMC137477 Posttranslational modifications in the CP43 subunit of photosystem II Lorraine B. Anderson, Melissa Maderia, Anthony J. A. Ouellette, Cindy Putnam-Evans, LeeAnn Higgins, Thomas Krick, Michael J. MacCoss, Hanjo Lim, John R. Yates, III, and Bridgette A. Barry PMCID: PMC137478 From the Cover:
Drusen proteome analysis: An approach to the etiology of age-related macular degeneration John W. Crabb, Masaru Miyagi, Xiaorong Gu, Karen Shadrach, Karen A. West, Hirokazu Sakaguchi, Motohiro Kamei, Azeem Hasan, Lin Yan, Mary E. Rayborn, Robert G. Salomon, and Joe G. Hollyfield PMCID: PMC137479 Catalysis of amide synthesis by RNA phosphodiester and hydroxyl groups Stacy I. Chamberlin, Edward J. Merino, and Kevin M. Weeks PMCID: PMC137480 A ligand for the aryl hydrocarbon receptor isolated from lung Jiasheng Song, Margaret Clagett-Dame, Richard E. Peterson, Mark E. Hahn, William M. Westler, Rafal R. Sicinski, and Hector F. DeLuca PMCID: PMC137481 Conformational energetics of stable and metastable states formed by DNA triplet repeat oligonucleotides: Implications for triplet expansion diseases J. Völker, N. Makube, G. E. Plum, H. H. Klump, and K. J. Breslauer PMCID: PMC137482 Transcriptional activating regions target a cyclin-dependent kinase Aseem Z. Ansari, Sang Seok Koh, Zafar Zaman, Christine Bongards, Norbert Lehming, Richard A. Young, and Mark Ptashne PMCID: PMC137483 A single point mutation in ecdysone receptor leads to increased ligand specificity: Implications for gene switch applications M. B. Kumar, T. Fujimoto, D. W. Potter, Q. Deng, and S. R. Palli PMCID: PMC137484 Confirmation by FRET in individual living cells of the absence of significant amyloid β-mediated caspase 8 activation Reiko Onuki, Akira Nagasaki, Hiroaki Kawasaki, Tadashi Baba, Taro Q. P. Uyeda, and Kazunari Taira PMCID: PMC137485 Pre-steady-state DNA unwinding by bacteriophage T4 Dda helicase reveals a monomeric molecular motor Bindu Nanduri, Alicia K. Byrd, Robert L. Eoff, Alan J. Tackett, and Kevin D. Raney PMCID: PMC137486 Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130 Masahiko Hayashi, Mun-Chual Rho, Akiko Enomoto, Akiko Fukami, Yong-Pil Kim, Yuji Kikuchi, Toshiaki Sunazuka, Tomoyasu Hirose, Kanki Komiyama, and Satoshi Omura PMCID: PMC137487 Differentiation of Hdm2-mediated p53 ubiquitination and Hdm2 autoubiquitination activity by small molecular weight inhibitors Zhihong Lai, Tao Yang, Young B. Kim, Thais M. Sielecki, Melody A. Diamond, Peter Strack, Mark Rolfe, Maureen Caligiuri, Pamela A. Benfield, Kurt R. Auger, and Robert A. Copeland PMCID: PMC137488 Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Gαq/11 pathway Sang-Kyou Han, Xinzhong Dong, Jong-Ik Hwang, Mark J. Zylka, David J. Anderson, and Melvin I. Simon PMCID: PMC137489 The catalytic domain of RNase E shows inherent 3′ to 5′ directionality in cleavage site selection Yanan Feng, Timothy A. Vickers, and Stanley N. Cohen PMCID: PMC137490 The catalytic cycle of β-lactam synthetase observed by x-ray crystallographic snapshots Matthew T. Miller, Brian O. Bachmann, Craig A. Townsend, and Amy C. Rosenzweig PMCID: PMC137491 Biophysics The structure and evolution of the major capsid protein of a large, lipid-containing DNA virus Narayanasamy Nandhagopal, Alan A. Simpson, James R. Gurnon, Xiadong Yan, Timothy S. Baker, Michael V. Graves, James L. Van Etten, and Michael G. Rossmann PMCID: PMC137492 INAUGURAL ARTICLE by a Recently Elected Academy Member: Finding important sites in protein sequences Peter J. Bickel, Katherina J. Kechris, Philip C. Spector, Gary J. Wedemayer, and Alexander N. Glazer PMCID: PMC137493 Cytoskeletal-assisted dynamics of the mitochondrial reticulum in living cells Michelle K. Knowles, Marina G. Guenza, Roderick A. Capaldi, and Andrew H. Marcus PMCID: PMC137494 Structural features of cytochrome c′ folding intermediates revealed by fluorescence energy-transfer kinetics Jennifer C. Lee, K. Cecilia Engman, F. Akif Tezcan, Harry B. Gray, and Jay R. Winkler PMCID: PMC137495 Cell Biology Estrogen receptor-interacting protein that modulates its nongenomic activity-crosstalk with Src/Erk phosphorylation cascade Chi-Wai Wong, Christopher McNally, Elliot Nickbarg, Barry S. Komm, and Boris J. Cheskis PMCID: PMC137496 Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal Vivienne I. Rebel, Andrew L. Kung, Elizabeth A. Tanner, Hong Yang, Roderick T. Bronson, and David M. Livingston PMCID: PMC137497 Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints Hui Zhao, Janis L. Watkins, and Helen Piwnica-Worms PMCID: PMC137498 Coordination of the two heads of myosin during muscle contraction Diane S. Lidke and David D. Thomas PMCID: PMC137499 Heme deficiency may be a factor in the mitochondrial and neuronal decay of aging Hani Atamna, David W. Killilea, Alison Nisbet Killilea, and Bruce N. Ames PMCID: PMC137500 From the Cover:
DE-cadherin-mediated cell adhesion is essential for maintaining somatic stem cells in the Drosophila ovary Xiaoqing Song and Ting Xie PMCID: PMC137501 Molecular characterization of mouse gastric epithelial progenitor cells Jason C. Mills, Niklas Andersson, Chieu V. Hong, Thaddeus S. Stappenbeck, and Jeffrey I. Gordon PMCID: PMC137502 Transcriptome analysis during cell division in plants Peter Breyne, Rozemarijn Dreesen, Klaas Vandepoele, Lieven De Veylder, Frank Van Breusegem, Lindy Callewaert, Stephane Rombauts, Jeroen Raes, Bernard Cannoot, Gilbert Engler, Dirk Inzé, and Marc Zabeau PMCID: PMC137503 A chemoattractant for ascidian spermatozoa is a sulfated steroid Manabu Yoshida, Michio Murata, Kazuo Inaba, and Masaaki Morisawa PMCID: PMC137504 Amino acids regulate the intracellular trafficking of the general amino acid permease of Saccharomyces cerevisiae Esther J. Chen and Chris A. Kaiser PMCID: PMC137505 Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3 Xiao-Bo Qiu and Alfred L. Goldberg PMCID: PMC137506 Synthetic small inhibiting RNAs: Efficient tools to inactivate oncogenic mutations and restore p53 pathways Luis Alfonso Martinez, Irina Naguibneva, Heike Lehrmann, Arlette Vervisch, Thierry Tchénio, Guillermina Lozano, and Annick Harel-Bellan PMCID: PMC137507 Developmental Biology Potentiation of serum response factor activity by a family of myocardin-related transcription factors Da-Zhi Wang, Shijie Li, Dirk Hockemeyer, Lillian Sutherland, Zhigao Wang, Gerhard Schratt, James A. Richardson, Alfred Nordheim, and Eric N. Olson PMCID: PMC137508 In vivo stabilization of the Dnmt1 (cytosine-5)- methyltransferase protein Feng Ding and J. Richard Chaillet PMCID: PMC137509 Ecology Evidence of hybridity in invasive watermilfoil (Myriophyllum) populations Michael L. Moody and Donald H. Les PMCID: PMC137510 The inflationary effects of environmental fluctuations in source–sink systems Andrew Gonzalez and Robert D. Holt PMCID: PMC137511 Evolution Dobzhansky–Muller incompatibilities in protein evolution Alexey S. Kondrashov, Shamil Sunyaev, and Fyodor A. Kondrashov PMCID: PMC137512 Female investment is retarded pending reception of allosperm in a hermaphroditic colonial invertebrate Roger N. Hughes, Patricio H. Manríquez, and John D. D. Bishop PMCID: PMC137513 The evolution of fungus-growing termites and their mutualistic fungal symbionts Duur K. Aanen, Paul Eggleton, Corinne Rouland-Lefèvre, Tobias Guldberg-Frøslev, Søren Rosendahl, and Jacobus J. Boomsma PMCID: PMC137514 Origin of plant glycerol transporters by horizontal gene transfer and functional recruitment Rafael Zardoya, Xiaodong Ding, Yoshichika Kitagawa, and Maarten J. Chrispeels PMCID: PMC137515 Uncoupling direct and indirect components of female choice in the wild Ryan Calsbeek and Barry Sinervo PMCID: PMC137516 Genetics Combining mapping and arraying: An approach to candidate gene identification M. L. Wayne and L. M. McIntyre PMCID: PMC137517 Metabolic specialization associated with phenotypic switching in Candida albicans Chung-Yu Lan, George Newport, Luis A. Murillo, Ted Jones, Stewart Scherer, Ronald W. Davis, and Nina Agabian PMCID: PMC137518 Coordinate regulation of energy transduction modules in Halobacterium sp. analyzed by a global systems approach Nitin S. Baliga, Min Pan, Young Ah Goo, Eugene C. Yi, David R. Goodlett, Krassen Dimitrov, Paul Shannon, Ruedi Aebersold, Wailap Victor Ng, and Leroy Hood PMCID: PMC137519 Production of maternal-zygotic mutant zebrafish by germ-line replacement Brian Ciruna, Gilbert Weidinger, Holger Knaut, Bernard Thisse, Christine Thisse, Erez Raz, and Alexander F. Schier PMCID: PMC137520 Expression profiling of CD34+ hematopoietic stem/ progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia Zhijian Qian, Anthony A. Fernald, Lucy A. Godley, Richard A. Larson, and Michelle M. Le Beau PMCID: PMC137521 Production of transgenic rats by lentiviral transduction of male germ-line stem cells F. Kent Hamra, Joel Gatlin, Karen M. Chapman, Dana M. Grellhesl, J. Victor Garcia, Robert E. Hammer, and David L. Garbers PMCID: PMC137522 Mbd4 inactivation increases C→T transition mutations and promotes gastrointestinal tumor formation Edmund Wong, Kan Yang, Mari Kuraguchi, Uwe Werling, Elena Avdievich, Kunhua Fan, Melissa Fazzari, Bo Jin, Anthony M. C. Brown, Martin Lipkin, and Winfried Edelmann PMCID: PMC137523 Retroviral delivery of small interfering RNA into primary cells Gregory M. Barton and Ruslan Medzhitov PMCID: PMC137524 The Usher syndrome proteins cadherin 23 and harmonin form a complex by means of PDZ-domain interactions Jan Siemens, Piotr Kazmierczak, Anna Reynolds, Melanie Sticker, Amanda Littlewood-Evans, and Ulrich Müller PMCID: PMC137525 The observed human sperm mutation frequency cannot explain the achondroplasia paternal age effect Irene Tiemann-Boege, William Navidi, Raji Grewal, Dan Cohn, Brenda Eskenazi, Andrew J. Wyrobek, and Norman Arnheim PMCID: PMC137526 The Coprinus cinereus adherin Rad9 functions in Mre11-dependent DNA repair, meiotic sister-chromatid cohesion, and meiotic homolog pairing W. Jason Cummings, Sandra T. Merino, Kevin G. Young, Libo Li, Christopher W. Johnson, Elizabeth A. Sierra, and Miriam E. Zolan PMCID: PMC137527 The phage λ CII transcriptional activator carries a C-terminal domain signaling for rapid proteolysis Oren Kobiler, Simi Koby, Dinah Teff, Donald Court, and Amos B. Oppenheim PMCID: PMC137528 Repair of topoisomerase I covalent complexes in the absence of the tyrosyl-DNA phosphodiesterase Tdp1 Chunyan Liu, Jeffrey J. Pouliot, and Howard A. Nash PMCID: PMC137529 Biological models and genes of tumor reversion: Cellular reprogramming through tpt1/TCTP and SIAH-1 Marcel Tuynder, Laurent Susini, Sylvie Prieur, Stéphanie Besse, Giusy Fiucci, Robert Amson, and Adam Telerman PMCID: PMC137530 Missense models [Gustm(E536A)Sly, Gustm(E536Q)Sly, and Gustm(L175F)Sly] of murine mucopolysaccharidosis type VII produced by targeted mutagenesis Shunji Tomatsu, Koji O. Orii, Carole Vogler, Jeffrey H. Grubb, Elizabeth M. Snella, Monica A. Gutierrez, Tatiana Dieter, Kazuko Sukegawa, Tadao Orii, Naomi Kondo, and William S. Sly PMCID: PMC137531 Transcriptional profiles associated with aging and middle age-onset caloric restriction in mouse hearts Cheol-Koo Lee, David B. Allison, Jaap Brand, Richard Weindruch, and Tomas A. Prolla PMCID: PMC137532 From the Cover:
Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice Federica Di Palma, Inna A. Belyantseva, Hung J. Kim, Thomas F. Vogt, Bechara Kachar, and Konrad Noben-Trauth PMCID: PMC137533 Gene expression comparison of biopsies from Duchenne muscular dystrophy (DMD) and normal skeletal muscle Judith N. Haslett, Despina Sanoudou, Alvin T. Kho, Richard R. Bennett, Steven A. Greenberg, Isaac S. Kohane, Alan H. Beggs, and Louis M. Kunkel PMCID: PMC137534 Immunology Human CD8+ T cells do not require the polarization of lipid rafts for activation and proliferation Birgit Kovacs, Marcela V. Maus, James L. Riley, Geo S. Derimanov, Gary A. Koretzky, Carl H. June, and Terri H. Finkel PMCID: PMC137535 Presentation of antagonist peptides to naive CD4+ T cells abrogates spatial reorganization of class II MHC peptide complexes on the surface of dendritic cells Bartosz Chmielowski, Rafal Pacholczyk, Piotr Kraj, Pawel Kisielow, and Leszek Ignatowicz PMCID: PMC137536 Negative autoregulation of BCL-6 is bypassed by genetic alterations in diffuse large B cell lymphomas Xing Wang, Zhiping Li, Akira Naganuma, and B. Hilda Ye PMCID: PMC137537 Quantifying signaling-induced reorientation of T cell receptors during immunological synapse formation William C. Moss, Darrell J. Irvine, Mark M. Davis, and Matthew F. Krummel PMCID: PMC137538 Identification of E2A target genes in B lymphocyte development by using a gene tagging-based chromatin immunoprecipitation system Stephen Greenbaum and Yuan Zhuang PMCID: PMC137539 Medical Sciences Glycoprotein gp110 of Epstein–Barr virus determines viral tropism and efficiency of infection B. Neuhierl, R. Feederle, W. Hammerschmidt, and H. J. Delecluse PMCID: PMC137540 Down-regulation of parkin protein in transient focal cerebral ischemia: A link between stroke and degenerative disease? Thorsten Mengesdorf, Poul H. Jensen, Günter Mies, Christoph Aufenberg, and Wulf Paschen PMCID: PMC137541 Effects of long-term treatment with the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl and the LHRH antagonist Cetrorelix on the levels of pituitary LHRH receptors and their mRNA expression in rats Judit E. Horvath, Ana M. Bajo, Andrew V. Schally, Magdolna Kovacs, Francine Herbert, and Kate Groot PMCID: PMC137542 Finding genetic contributions to sporadic disease: A recessive locus at 12q24 commonly contributes to patent ductus arteriosus Arya Mani, Seyed-Mahmoud Meraji, Roozbeh Houshyar, Jayaram Radhakrishnan, Alaleh Mani, Mehrabeh Ahangar, Tayebeh M. Rezaie, Mohammad-Ali Taghavinejad, Behrooz Broumand, Hongyu Zhao, Carol Nelson-Williams, and Richard P. Lifton PMCID: PMC137543 The lipid phosphatase myotubularin is essential for skeletal muscle maintenance but not for myogenesis in mice Anna Buj-Bello, Vincent Laugel, Nadia Messaddeq, Hala Zahreddine, Jocelyn Laporte, Jean-François Pellissier, and Jean-Louis Mandel PMCID: PMC524320 Increased mitochondrial mass in mitochondrial myopathy mice Anna Wredenberg, Rolf Wibom, Hans Wilhelmsson, Caroline Graff, Heidi H. Wiener, Steven J. Burden, Anders Oldfors, Håkan Westerblad, and Nils-Göran Larsson PMCID: PMC137544 Proliferative action of mast-cell tryptase is mediated by PAR2, COX2, prostaglandins, and PPARγ: Possible relevance to human fibrotic disorders Mónica B. Frungieri, Stephan Weidinger, Viktor Meineke, Frank M. Köhn, and Artur Mayerhofer PMCID: PMC137545 Expression of human epileptic temporal lobe neurotransmitter receptors in Xenopus oocytes: An innovative approach to study epilepsy Eleonora Palma, Vincenzo Esposito, Anna Maria Mileo, Giancarlo Di Gennaro, Pierpaolo Quarato, Felice Giangaspero, Ciriaco Scoppetta, Paolo Onorati, Flavia Trettel, Ricardo Miledi, and Fabrizio Eusebi PMCID: PMC137546 A previously undescribed chemical link between smoking and metabolic disease Tobin J. Dickerson and Kim D. Janda PMCID: PMC137547 Antiepileptic drugs and apoptotic neurodegeneration in the developing brain Petra Bittigau, Marco Sifringer, Kerstin Genz, Ellen Reith, Dana Pospischil, Suresh Govindarajalu, Mark Dzietko, Stefanie Pesditschek, Ingrid Mai, Krikor Dikranian, John W. Olney, and Chrysanthy Ikonomidou PMCID: PMC137548 Multistage carcinogenesis and the incidence of colorectal cancer E. Georg Luebeck and Suresh H. Moolgavkar PMCID: PMC137549 Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia Joseph L. Wiemels, Brian C. Leonard, Yunxia Wang, Mark R. Segal, Stephen P. Hunger, Martyn T. Smith, Vonda Crouse, Xiaomei Ma, Patricia A. Buffler, and Sharon R. Pine PMCID: PMC137550 Microbiology East Asian genotypes of Helicobacter pylori strains in Amerindians provide evidence for its ancient human carriage Chandrabali Ghose, Guillermo I. Perez-Perez, Maria-Gloria Dominguez-Bello, David T. Pride, Claudio M. Bravi, and Martin J. Blaser PMCID: PMC137551 Analysis of optimality in natural and perturbed metabolic networks Daniel Segrè, Dennis Vitkup, and George M. Church PMCID: PMC137552 Replicating hepatitis delta virus RNA is edited in the nucleus by the small form of ADAR1 Swee Kee Wong and David W. Lazinski PMCID: PMC137553 Engineered herpes simplex virus 1 is dependent on IL13Rα2 receptor for cell entry and independent of glycoprotein D receptor interaction Guoying Zhou, Guo-Jie Ye, Waldemar Debinski, and Bernard Roizman PMCID: PMC137554 Reactivation of a complex retrovirus is controlled by a molecular switch and is inhibited by a viral protein Christopher D. Meiering and Maxine L. Linial PMCID: PMC137555 Cag pathogenicity island-specific responses of gastric epithelial cells to Helicobacter pylori infection Karen Guillemin, Nina R. Salama, Lucy S. Tompkins, and Stanley Falkow PMCID: PMC137556 Neuroscience Time-lapse imaging of a dynamic phosphorylation-dependent protein–protein interaction in mammalian cells James M. Spotts, Ricardo E. Dolmetsch, and Michael E. Greenberg PMCID: PMC137557 Transneuronal tracing of diverse CNS circuits by Cre-mediated induction of wheat germ agglutinin in transgenic mice Joao M. Braz, Beatriz Rico, and Allan I. Basbaum PMCID: PMC137558 Neuroendocrine control of a sexually dimorphic behavior by a few neurons of the pars intercerebralis in Drosophila Yesser Hadj Belgacem and Jean-René Martin PMCID: PMC137559 Motion perception of saccade-induced retinal translation Eric Castet, Sébastien Jeanjean, and Guillaume S. Masson PMCID: PMC137560 Shape perception reduces activity in human primary visual cortex Scott O. Murray, Daniel Kersten, Bruno A. Olshausen, Paul Schrater, and David L. Woods PMCID: PMC137561 Altered kinetics and benzodiazepine sensitivity of a GABAA receptor subunit mutation [γ2(R43Q)] found in human epilepsy David N. Bowser, David A. Wagner, Cynthia Czajkowski, Brett A. Cromer, Michael W. Parker, Robyn H. Wallace, Louise A. Harkin, John C. Mulley, Carla Marini, Samuel F. Berkovic, David A. Williams, Mathew V. Jones, and Steven Petrou PMCID: PMC137562 Spectral mixing of rhythmic neuronal signals in sensory cortex Kurt F. Ahrens, Herbert Levine, Harry Suhl, and David Kleinfeld PMCID: PMC137563 Laminar specificity of functional MRI onset times during somatosensory stimulation in rat Afonso C. Silva and Alan P. Koretsky PMCID: PMC137564 Caspase activation and neuroprotection in caspase-3- deficient mice after in vivo cerebral ischemia and in vitro oxygen glucose deprivation Dean A. Le, Yongqin Wu, Zhihong Huang, Kohji Matsushita, Nikolaus Plesnila, Jean C. Augustinack, Bradley T. Hyman, Junying Yuan, Keisuke Kuida, Richard A. Flavell, and Michael A. Moskowitz PMCID: PMC137565 RNA-binding protein Musashi family: Roles for CNS stem cells and a subpopulation of ependymal cells revealed by targeted disruption and antisense ablation Shin-ichi Sakakibara, Yuki Nakamura, Tetsu Yoshida, Shinsuke Shibata, Masato Koike, Hiroshi Takano, Shuichi Ueda, Yasuo Uchiyama, Tetsuo Noda, and Hideyuki Okano PMCID: PMC137566 Viable hypomorphic signaling mutant of the Met receptor reveals a role for hepatocyte growth factor in postnatal cerebellar development Alessandro Ieraci, Paolo E. Forni, and Carola Ponzetto PMCID: PMC137567 Plant Biology From the Cover:
A Lotus basic leucine zipper protein with a RING-finger motif negatively regulates the developmental program of nodulation Rieko Nishimura, Masayuki Ohmori, Hironori Fujita, and Masayoshi Kawaguchi PMCID: PMC137568 Control of photoperiod-regulated tuberization in potato by the Arabidopsis flowering-time gene CONSTANS Jaime F. Martínez-García, Ariadna Virgós-Soler, and Salomé Prat PMCID: PMC137569 Expression of the antiapoptotic baculovirus p35 gene in tomato blocks programmed cell death and provides broad-spectrum resistance to disease James E. Lincoln, Craig Richael, Bert Overduin, Kathy Smith, Richard Bostock, and David G. Gilchrist PMCID: PMC137570 PsbS-dependent enhancement of feedback de-excitation protects photosystem II from photoinhibition Xiao-Ping Li, Patricia Müller-Moulé, Adam M. Gilmore, and Krishna K. Niyogi PMCID: PMC137571 From the Cover:
A viral suppressor of RNA silencing differentially regulates the accumulation of short interfering RNAs and micro-RNAs in tobacco Allison C. Mallory, Brenda J. Reinhart, David Bartel, Vicki B. Vance, and Lewis H. Bowman PMCID: PMC137572 Population Biology Herpes viruses hedge their bets Michael P. H. Stumpf, Zoë Laidlaw, and Vincent A. A. Jansen PMCID: PMC137573 Psychology (Biological Sciences) Distinct neural systems subserve person and object knowledge Jason P. Mitchell, Todd F. Heatherton, and C. Neil Macrae PMCID: PMC137574 Corrections Proc Natl Acad Sci U S A. 2002 November 12; 99(23): 15244. Published online 2002 November 1. doi: 10.1073/pnas.242607799.PMCID: PMC133618 Corrects: Michael Q. Zhang. Extracting functional information from microarrays: A challenge for functional genomics. Proc Natl Acad Sci U S A. 2002 October 1; 99(20): 12509–12511. Proc Natl Acad Sci U S A. 2002 November 12; 99(23): 15244. Published online 2002 November 1. doi: 10.1073/pnas.222533199.PMCID: PMC133619 Corrects: Bing Gong, et al. Creating nanocavities of tunable sizes: Hollow helices. Proc Natl Acad Sci U S A. 2002 September 3; 99(18): 11583–11588. Proc Natl Acad Sci U S A. 2002 November 12; 99(23): 15244. Published online 2002 October 25. doi: 10.1073/pnas.242581399.PMCID: PMC133620 Corrects: Boris N. Kholodenko, et al. Untangling the wires: A strategy to trace functional interactions in signaling and gene networks. Proc Natl Acad Sci U S A. 2002 October 1; 99(20): 12841–12846. Proc Natl Acad Sci U S A. 2002 November 12; 99(23): 15244. Published online 2002 November 1. doi: 10.1073/pnas.242617899.PMCID: PMC133621 Corrects: Shuyuan Yeh, et al. Generation and characterization of androgen receptor knockout (ARKO) mice: An in vivo model for the study of androgen functions in selective tissues. Proc Natl Acad Sci U S A. 2002 October 15; 99(21): 13498–13503. Proc Natl Acad Sci U S A. 2002 November 12; 99(23): 15244. Published online 2002 October 25. doi: 10.1073/pnas.222520199.PMCID: PMC133622 Corrects: Maximilian Diehn, et al. Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation. Proc Natl Acad Sci U S A. 2002 September 3; 99(18): 11796–11801. |
