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Global regulatory logic for specification of an embryonic cell lineage Paola Oliveri, Qiang Tu, and Eric H. Davidson PMCID: PMC2329687 Letters Lithium may slow progression of amyotrophic lateral sclerosis, but further study is needed Richard S. Bedlack, Nicholas Maragakis, and Terry Heiman-Patterson PMCID: PMC2329692 Reply to Bedlack et al.: A small pilot study calls for large clinical trials to evaluate the effects of lithium before prescribing the drug for amyotrophic lateral sclerosis Francesco Fornai, Gabriele Siciliano, Maria Laura Manca, Luigi Murri, Antonio Paparelli, and Stefano Ruggieri PMCID: PMC2329707 This Week in PNAS Proc Natl Acad Sci U S A. 2008 April 22; 105(16): 5947–5948. doi: 10.1073/iti1608105.PMCID: PMC2329723 Commentaries Vesicular ATP transport is a hard (V)NUT to crack Gary Rudnick PMCID: PMC2329674 Gene regulatory networks and embryonic specification Leroy Hood PMCID: PMC2329716 Understanding epilepsy through network modeling Astrid A. Prinz PMCID: PMC2329695 Physical Sciences Applied Mathematics The influence of cochlear shape on low-frequency hearing Daphne Manoussaki, Richard S. Chadwick, Darlene R. Ketten, Julie Arruda, Emilios K. Dimitriadis, and Jen T. O'Malley PMCID: PMC2299218 Chemistry From biosilicification to tailored materials: Optimizing hydrophobic domains and resistance to protonation of polyamines David J. Belton, Siddharth V. Patwardhan, Vadim V. Annenkov, Elena N. Danilovtseva, and Carole C. Perry PMCID: PMC2329702 Physics Proton order in the ice crystal surface V. Buch, H. Groenzin, I. Li, M. J. Shultz, and E. Tosatti PMCID: PMC2329717 Biological Sciences Agricultural Sciences Mitochondrial heteroplasmy and the evolution of insecticide resistance: Non-Mendelian inheritance in action Thomas Van Leeuwen, Bartel Vanholme, Steven Van Pottelberge, Pieter Van Nieuwenhuyse, Ralf Nauen, Luc Tirry, and Ian Denholm PMCID: PMC2329677 Biochemistry From the Cover:
Combinatorial antibody libraries from survivors of the Turkish H5N1 avian influenza outbreak reveal virus neutralization strategies Arun K. Kashyap, John Steel, Ahmet F. Oner, Michael A. Dillon, Ryann E. Swale, Katherine M. Wall, Kimberly J. Perry, Aleksandr Faynboym, Mahmut Ilhan, Michael Horowitz, Lawrence Horowitz, Peter Palese, Ramesh R. Bhatt, and Richard A. Lerner PMCID: PMC2329690 Mechanism of Cu+-transporting ATPases: Soluble Cu+ chaperones directly transfer Cu+ to transmembrane transport sites Manuel González-Guerrero and José M. Argüello PMCID: PMC2329688 Dephosphorylation of 2,3-bisphosphoglycerate by MIPP expands the regulatory capacity of the Rapoport–Luebering glycolytic shunt Jaiesoon Cho, Jason S. King, Xun Qian, Adrian J. Harwood, and Stephen B. Shears PMCID: PMC2329705 Alteration of cyclin D1 transcript elongation by a mutated transcription factor up-regulates the oncogenic D1b splice isoform in cancer Gabriel Sanchez, Danielle Bittencourt, Karine Laud, Jérôme Barbier, Olivier Delattre, Didier Auboeuf, and Martin Dutertre PMCID: PMC2329709 Identification and evolution of fungal mitochondrial tyrosyl-tRNA synthetases with group I intron splicing activity Paul J. Paukstelis and Alan M. Lambowitz PMCID: PMC2329719 Biophysics The mitotic kinesin CENP-E is a processive transport motor Hasan Yardimci, Marilyn van Duffelen, Yinghui Mao, Steven S. Rosenfeld, and Paul R. Selvin PMCID: PMC2329722 Conservation of the regulated structure of folded myosin 2 in species separated by at least 600 million years of independent evolution Hyun Suk Jung, Stan A. Burgess, Neil Billington, Melanie Colegrave, Hitesh Patel, Joseph M. Chalovich, Peter D. Chantler, and Peter J. Knight PMCID: PMC2329715 Role of the familial Dutch mutation E22Q in the folding and aggregation of the 15–28 fragment of the Alzheimer amyloid-β protein Andrij Baumketner, Mary Griffin Krone, and Joan-Emma Shea PMCID: PMC2329720 Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane Maarten F. M. Engel, Lucie Khemtémourian, Cécile C. Kleijer, Hans J. D. Meeldijk, Jet Jacobs, Arie J. Verkleij, Ben de Kruijff, J. Antoinette Killian, and Jo W. M. Höppener PMCID: PMC2329711 Intrinsic noise, dissipation cost, and robustness of cellular networks: The underlying energy landscape of MAPK signal transduction Saul Lapidus, Bo Han, and Jin Wang PMCID: PMC2329678 TRIM21 is an IgG receptor that is structurally, thermodynamically, and kinetically conserved Anthony H. Keeble, Zahra Khan, Alan Forster, and Leo C. James PMCID: PMC2329685 Cell Biology Multiple kinases in the interferon-γ response D. Watling, C. R. Carmo, I. M. Kerr, and A. P. Costa-Pereira PMCID: PMC2329710 PU.1 and C/EBPα/β convert fibroblasts into macrophage-like cells Ru Feng, Sabrina C. Desbordes, Huafeng Xie, Ester Sanchez Tillo, Fiona Pixley, E. Richard Stanley, and Thomas Graf PMCID: PMC2327209 Cardiogenic small molecules that enhance myocardial repair by stem cells Hesham Sadek, Britta Hannack, Elizabeth Choe, Jessica Wang, Shuaib Latif, Mary G. Garry, Daniel J. Garry, Jamie Longgood, Doug E. Frantz, Eric N. Olson, Jenny Hsieh, and Jay W. Schneider PMCID: PMC2329693 Different phosphorylation states of the anaphase promoting complex in response to antimitotic drugs: A quantitative proteomic analysis Judith A. J. Steen, Hanno Steen, Ann Georgi, Kenneth Parker, Michael Springer, Marc Kirchner, Fred Hamprecht, and Marc W. Kirschner PMCID: PMC2329673 Effective chromosome pairing requires chromatin remodeling at the onset of meiosis Isabelle Colas, Peter Shaw, Pilar Prieto, Michael Wanous, Wolfgang Spielmeyer, Rohit Mago, and Graham Moore PMCID: PMC2329686 Developmental Biology From the Cover: Feature Article:
Global regulatory logic for specification of an embryonic cell lineage Paola Oliveri, Qiang Tu, and Eric H. Davidson PMCID: PMC2329687 Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2 Jinsheng Weng, Jian Luo, Xuhong Cheng, Chang Jin, Xiangtian Zhou, Jia Qu, LiLi Tu, Di Ai, Dali Li, Jun Wang, James F. Martin, Brad A. Amendt, and Mingyao Liu PMCID: PMC2329706 Ecology From the Cover:
Higher effect of plant species diversity on productivity in natural than artificial ecosystems Pedro Flombaum and Osvaldo E. Sala PMCID: PMC2329694 Evolution Transfer of a large gene regulatory apparatus to a new developmental address in echinoid evolution Feng Gao and Eric H. Davidson PMCID: PMC2329712 Higher origination and extinction rates in larger mammals Lee Hsiang Liow, Mikael Fortelius, Ella Bingham, Kari Lintulaakso, Heikki Mannila, Larry Flynn, and Nils Chr. Stenseth PMCID: PMC2329699 Genetics Adenovirus E1A targets p400 to induce the cellular oncoprotein Myc Kathryn A. Tworkowski, Abhishek A. Chakraborty, Andrew V. Samuelson, Yvette R. Seger, Masako Narita, Gregory J. Hannon, Scott W. Lowe, and William P. Tansey PMCID: PMC2329713 Immunology The antibody zalutumumab inhibits epidermal growth factor receptor signaling by limiting intra- and intermolecular flexibility Jeroen J. Lammerts van Bueren, Wim K. Bleeker, Annika Brännström, Anne von Euler, Magnus Jansson, Matthias Peipp, Tanja Schneider-Merck, Thomas Valerius, Jan G. J. van de Winkel, and Paul W. H. I. Parren PMCID: PMC2329681 Sparse production but preferential incorporation of recently produced naïve T cells in the human peripheral pool Nienke Vrisekoop, Ineke den Braber, Anne Bregje de Boer, An F. C. Ruiter, Mariëtte T. Ackermans, Saskia N. van der Crabben, Elise H. R. Schrijver, Gerrit Spierenburg, Hans P. Sauerwein, Mette D. Hazenberg, Rob J. de Boer, Frank Miedema, José A. M. Borghans, and Kiki Tesselaar PMCID: PMC2329696 Dendritic cells in islets of Langerhans constitutively present β cell-derived peptides bound to their class II MHC molecules Boris Calderon, Anish Suri, Mark J. Miller, and Emil R. Unanue PMCID: PMC2329714 Medical Sciences Global metabolic responses of mice to Trypanosoma brucei brucei infection Yulan Wang, Jürg Utzinger, Jasmina Saric, Jia V. Li, Jean Burckhardt, Stephan Dirnhofer, Jeremy K. Nicholson, Burton H. Singer, Reto Brun, and Elaine Holmes PMCID: PMC2329718 The evolutionarily conserved G protein-coupled receptor SREB2/GPR85 influences brain size, behavior, and vulnerability to schizophrenia Mitsuyuki Matsumoto, Richard E. Straub, Stefano Marenco, Kristin K. Nicodemus, Shun-ichiro Matsumoto, Akihiko Fujikawa, Sosuke Miyoshi, Miwako Shobo, Shinji Takahashi, Junko Yarimizu, Masatoshi Yuri, Masashi Hiramoto, Shuji Morita, Hiroyuki Yokota, Takeshi Sasayama, Kazuhiro Terai, Masayasu Yoshino, Akira Miyake, Joseph H. Callicott, Michael F. Egan, Andreas Meyer-Lindenberg, Lucas Kempf, Robyn Honea, Radha Krishna Vakkalanka, Jun Takasaki, Masazumi Kamohara, Takatoshi Soga, Hideki Hiyama, Hiroyuki Ishii, Ayako Matsuo, Shintaro Nishimura, Nobuya Matsuoka, Masato Kobori, Hitoshi Matsushime, Masao Katoh, Kiyoshi Furuichi, and Daniel R. Weinberger PMCID: PMC2299221 Adipogenic capacity and the susceptibility to type 2 diabetes and metabolic syndrome May-Yun Wang, Paul Grayburn, Shuyuan Chen, Mariella Ravazzola, Lelio Orci, and Roger H. Unger PMCID: PMC2329698 Microbiology Single-cell protein induction dynamics reveals a period of vulnerability to antibiotics in persister bacteria Orit Gefen, Chana Gabay, Michael Mumcuoglu, Giora Engel, and Nathalie Q. Balaban PMCID: PMC2329697 From the Cover:
Antiinflammatory cAMP signaling and cell migration genes co-opted by the anthrax bacillus Chun Kim, Sarah Wilcox-Adelman, Yasuyo Sano, Wei-Jen Tang, R. John Collier, and Jin Mo Park PMCID: PMC2329691 Global transcriptomic analysis of Cyanothece 51142 reveals robust diurnal oscillation of central metabolic processes Jana Stöckel, Eric A. Welsh, Michelle Liberton, Rangesh Kunnvakkam, Rajeev Aurora, and Himadri B. Pakrasi PMCID: PMC2329701 Neuroscience The influence of cochlear shape on low-frequency hearing Daphne Manoussaki, Richard S. Chadwick, Darlene R. Ketten, Julie Arruda, Emilios K. Dimitriadis, and Jen T. O'Malley PMCID: PMC2299218 Endogenous steroids and financial risk taking on a London trading floor J. M. Coates and J. Herbert PMCID: PMC2329689 Prediction of human errors by maladaptive changes in event-related brain networks Tom Eichele, Stefan Debener, Vince D. Calhoun, Karsten Specht, Andreas K. Engel, Kenneth Hugdahl, D. Yves von Cramon, and Markus Ullsperger PMCID: PMC2329680 From the Cover:
Nonrandom connectivity of the epileptic dentate gyrus predicts a major role for neuronal hubs in seizures Robert J. Morgan and Ivan Soltesz PMCID: PMC2299224 TNF receptor I sensitizes neurons to erythropoietin- and VEGF-mediated neuroprotection after ischemic and excitotoxic injury Era Taoufik, Edwige Petit, Didier Divoux, Vivian Tseveleki, Manuela Mengozzi, Michael L. Roberts, Samuel Valable, Pietro Ghezzi, John Quackenbush, Michael Brines, Anthony Cerami, and Lesley Probert PMCID: PMC2299225 Plant Biology Partitioned expression of duplicated genes during development and evolution of a single cell in a polyploid plant Ran Hovav, Joshua A. Udall, Bhupendra Chaudhary, Ryan Rapp, Lex Flagel, and Jonathan F. Wendel PMCID: PMC2329682 Nonuniform distribution of glucosinolates in Arabidopsis thaliana leaves has important consequences for plant defense Rohit Shroff, Fredd Vergara, Alexander Muck, Aleš Svatoš, and Jonathan Gershenzon PMCID: PMC2329684 Psychology Blood oxygenation level-dependent contrast response functions identify mechanisms of covert attention in early visual areas Xiangrui Li, Zhong-Lin Lu, Bosco S. Tjan, Barbara A. Dosher, and Wilson Chu PMCID: PMC2329700 Social Sciences Psychology An assessment of fixed-capacity models of visual working memory Jeffrey N. Rouder, Richard D. Morey, Nelson Cowan, Christopher E. Zwilling, Candice C. Morey, and Michael S. Pratte PMCID: PMC2329704 Corrections Correction for Wood et al., 6-Ethynylthieno[3,2-d]- and 6-ethynylthieno[2,3-d]pyrimidin-4-anilines as tunable covalent modifiers of ErbB kinases PMCID: PMC2329721 Corrects: Edgar R. Wood, et al. 6-Ethynylthieno[3,2-d]- and 6-ethynylthieno[2,3-d]pyrimidin-4-anilines as tunable covalent modifiers of ErbB kinases. Proc Natl Acad Sci U S A. 2008 February 26; 105(8): 2773–2778. Correction for del Mercato et al., Charge transport and intrinsic fluorescence in amyloid-like fibrils PMCID: PMC2329708 Corrects: Loretta Laureana del Mercato, et al. Charge transport and intrinsic fluorescence in amyloid-like fibrils. Proc Natl Acad Sci U S A. 2007 November 13; 104(46): 18019–18024. |
