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Volume 105(12);  March 25, 2008
Chemical Ecology Special Feature
Introductory Perspective
Chemical ecology in retrospect and prospect
Jerrold Meinwald and Thomas Eisner
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4539–4540. doi: 10.1073/pnas.0800649105.
PMCID: PMC2290750
Research Articles
The lost origin of chemical ecology in the late 19th century
Thomas Hartmann
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4541–4546. doi: 10.1073/pnas.0709231105.
PMCID: PMC2290813
Selection for chemical trait remixing in an invasive weed after reassociation with a coevolved specialist
A. R. Zangerl, M. C. Stanley, and M. R. Berenbaum
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4547–4552. doi: 10.1073/pnas.0710280105.
PMCID: PMC2290761
cis-Jasmone induces Arabidopsis genes that affect the chemical ecology of multitrophic interactions with aphids and their parasitoids
Toby J. A. Bruce, Michaela C. Matthes, Keith Chamberlain, Christine M. Woodcock, Abdul Mohib, Ben Webster, Lesley E. Smart, Michael A. Birkett, John A. Pickett, and Johnathan A. Napier
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4553–4558. doi: 10.1073/pnas.0710305105.
PMCID: PMC2290791
Herbivory-induced changes in the small-RNA transcriptome and phytohormone signaling in Nicotiana attenuata
Shree P. Pandey, Priyanka Shahi, Klaus Gase, and Ian T. Baldwin
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4559–4564. doi: 10.1073/pnas.0711363105.
PMCID: PMC2290812
Context- and scale-dependent effects of floral CO2 on nectar foraging by Manduca sexta
Joaquín Goyret, Poppy M. Markwell, and Robert A. Raguso
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4565–4570. doi: 10.1073/pnas.0708629105.
PMCID: PMC2290757
Seed odor mediates an obligate ant–plant mutualism in Amazonian rainforests
Elsa Youngsteadt, Satoshi Nojima, Christopher Häberlein, Stefan Schulz, and Coby Schal
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4571–4575. doi: 10.1073/pnas.0708643105.
PMCID: PMC2290770
From the Cover: Chemical Ecology Special Feature:
Evidence for olfactory search in wandering albatross, Diomedea exulans
Gabrielle A. Nevitt, Marcel Losekoot, and Henri Weimerskirch
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4576–4581. doi: 10.1073/pnas.0709047105.
PMCID: PMC2290754
Factors promoting marine invasions: A chemoecological approach
Ernesto Mollo, Margherita Gavagnin, Marianna Carbone, Francesco Castelluccio, Ferdinando Pozone, Vassilios Roussis, José Templado, Michael T. Ghiselin, and Guido Cimino
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4582–4586. doi: 10.1073/pnas.0709355105.
PMCID: PMC2290762
Evolution of polyketide synthases in bacteria
Christian P. Ridley, Ho Young Lee, and Chaitan Khosla
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4595–4600. doi: 10.1073/pnas.0710107105.
PMCID: PMC2290765
Perspective
Biosynthetic origin of natural products isolated from marine microorganism–invertebrate assemblages
T. Luke Simmons, R. Cameron Coates, Benjamin R. Clark, Niclas Engene, David Gonzalez, Eduardo Esquenazi, Pieter C. Dorrestein, and William H. Gerwick
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4587–4594. doi: 10.1073/pnas.0709851105.
PMCID: PMC2290810
The evolution of gene collectives: How natural selection drives chemical innovation
Michael A. Fischbach, Christopher T. Walsh, and Jon Clardy
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4601–4608. doi: 10.1073/pnas.0709132105.
PMCID: PMC2290807
Letter
Reply to Pape et al.: The phylogeography of HIV-1 group M subtype B
Michael Worobey, Arthur E. Pitchenik, M. Thomas P. Gilbert, Gabriela Wlasiuk, and Andrew Rambaut
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): E16. doi: 10.1073/pnas.0712128105.
PMCID: PMC2290816
This Week in PNAS
In This Issue
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4531–4532. doi: 10.1073/iti1208105.
PMCID: PMC2290819
Commentaries
Local knowledge helps determine protein structures
Michael R. Gryk and Jeffrey C. Hoch
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4533–4534. doi: 10.1073/pnas.0801069105.
PMCID: PMC2290792
The continuing evolution of a bacterial pathogen
James B. Kaper and Mohamed A. Karmali
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4535–4536. doi: 10.1073/pnas.0801435105.
PMCID: PMC2290787
SYMRK, an enigmatic receptor guarding and guiding microbial endosymbioses with plant roots
Marcelle Holsters
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4537–4538. doi: 10.1073/pnas.0801270105.
PMCID: PMC2290752
Physical Sciences
Applied Physical Sciences
Tug-of-war as a cooperative mechanism for bidirectional cargo transport by molecular motors
Melanie J. I. Müller, Stefan Klumpp, and Reinhard Lipowsky
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4609–4614. doi: 10.1073/pnas.0706825105.
PMCID: PMC2290779
Chemistry
Factors promoting marine invasions: A chemoecological approach
Ernesto Mollo, Margherita Gavagnin, Marianna Carbone, Francesco Castelluccio, Ferdinando Pozone, Vassilios Roussis, José Templado, Michael T. Ghiselin, and Guido Cimino
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4582–4586. doi: 10.1073/pnas.0709355105.
PMCID: PMC2290762
A two-step nucleotide-flipping mechanism enables kinetic discrimination of DNA lesions by AGT
Jie Hu, Ao Ma, and Aaron R. Dinner
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4615–4620. doi: 10.1073/pnas.0708058105.
PMCID: PMC2290773
Dipole tensor-based atomic-resolution structure determination of a nanocrystalline protein by solid-state NMR
W. Trent Franks, Benjamin J. Wylie, Heather L. Frericks Schmidt, Andrew J. Nieuwkoop, Rebecca-Maria Mayrhofer, Gautam J. Shah, Daniel T. Graesser, and Chad M. Rienstra
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4621–4626. doi: 10.1073/pnas.0712393105.
PMCID: PMC2290771
Incremental parameter evaluation from incomplete data with application to the population pharmacology of anticoagulants
Marcel O. Vlad, Alexandru Dan Corlan, Federico Morán, Peter Oefner, and John Ross
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4627–4632. doi: 10.1073/pnas.0711508105.
PMCID: PMC2290818
Computer Sciences
Tracing information flow on a global scale using Internet chain-letter data
David Liben-Nowell and Jon Kleinberg
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4633–4638. doi: 10.1073/pnas.0708471105.
PMCID: PMC2290760
Biological Sciences
Anthropology
Close correspondence between quantitative- and molecular-genetic divergence times for Neandertals and modern humans
Timothy D. Weaver, Charles C. Roseman, and Chris B. Stringer
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4645–4649. doi: 10.1073/pnas.0709079105.
PMCID: PMC2290803
The Homo floresiensis cranium (LB1): Size, scaling, and early Homo affinities
Adam D. Gordon, Lisa Nevell, and Bernard Wood
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4650–4655. doi: 10.1073/pnas.0710041105.
PMCID: PMC2290802
Applied Biological Sciences
Immunization by a bacterial aerosol
Lucila Garcia-Contreras, Yun-Ling Wong, Pavan Muttil, Danielle Padilla, Jerry Sadoff, Jessica DeRousse, Willem Andreas Germishuizen, Sunali Goonesekera, Katharina Elbert, Barry R. Bloom, Rich Miller, P. Bernard Fourie, Anthony Hickey, and David Edwards
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4656–4660. doi: 10.1073/pnas.0800043105.
PMCID: PMC2290758
Biochemistry
Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-Å structure of the heparin-bridged complex
Wei Li, Ty E. Adams, Jyoti Nangalia, Charles T. Esmon, and James A. Huntington
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4661–4666. doi: 10.1073/pnas.0711055105.
PMCID: PMC2290767
RNA-dependent lipid remodeling by bacterial multiple peptide resistance factors
Hervé Roy and Michael Ibba
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4667–4672. doi: 10.1073/pnas.0800006105.
PMCID: PMC2290796
The structure of LepA, the ribosomal back translocase
Robin N. Evans, Gregor Blaha, Scott Bailey, and Thomas A. Steitz
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4673–4678. doi: 10.1073/pnas.0801308105.
PMCID: PMC2290774
Biophysics
Tug-of-war as a cooperative mechanism for bidirectional cargo transport by molecular motors
Melanie J. I. Müller, Stefan Klumpp, and Reinhard Lipowsky
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4609–4614. doi: 10.1073/pnas.0706825105.
PMCID: PMC2290779
A two-step nucleotide-flipping mechanism enables kinetic discrimination of DNA lesions by AGT
Jie Hu, Ao Ma, and Aaron R. Dinner
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4615–4620. doi: 10.1073/pnas.0708058105.
PMCID: PMC2290773
Dipole tensor-based atomic-resolution structure determination of a nanocrystalline protein by solid-state NMR
W. Trent Franks, Benjamin J. Wylie, Heather L. Frericks Schmidt, Andrew J. Nieuwkoop, Rebecca-Maria Mayrhofer, Gautam J. Shah, Daniel T. Graesser, and Chad M. Rienstra
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4621–4626. doi: 10.1073/pnas.0712393105.
PMCID: PMC2290771
Reassessing a sparse energetic network within a single protein domain
Celestine N. Chi, Lisa Elfström, Yao Shi, Tord Snäll, Åke Engström, and Per Jemth
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4679–4684. doi: 10.1073/pnas.0711732105.
PMCID: PMC2290805
From the Cover:
Consistent blind protein structure generation from NMR chemical shift data
Yang Shen, Oliver Lange, Frank Delaglio, Paolo Rossi, James M. Aramini, Gaohua Liu, Alexander Eletsky, Yibing Wu, Kiran K. Singarapu, Alexander Lemak, Alexandr Ignatchenko, Cheryl H. Arrowsmith, Thomas Szyperski, Gaetano T. Montelione, David Baker, and Ad Bax
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4685–4690. doi: 10.1073/pnas.0800256105.
PMCID: PMC2290745
Myosin V and Kinesin act as tethers to enhance each others' processivity
M. Yusuf Ali, Hailong Lu, Carol S. Bookwalter, David M. Warshaw, and Kathleen M. Trybus
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4691–4696. doi: 10.1073/pnas.0711531105.
PMCID: PMC2290781
Unilamellar vesicle formation and encapsulation by microfluidic jetting
Jeanne C. Stachowiak, David L. Richmond, Thomas H. Li, Allen P. Liu, Sapun H. Parekh, and Daniel A. Fletcher
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4697–4702. doi: 10.1073/pnas.0710875105.
PMCID: PMC2290793
Monolayer purification: A rapid method for isolating protein complexes for single-particle electron microscopy
Deborah F. Kelly, Danijela Dukovski, and Thomas Walz
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4703–4708. doi: 10.1073/pnas.0800867105.
PMCID: PMC2290746
Cell Biology
X-inactivation in female human embryonic stem cells is in a nonrandom pattern and prone to epigenetic alterations
Yin Shen, Youko Matsuno, Shaun D. Fouse, Nagesh Rao, Sierra Root, Renhe Xu, Matteo Pellegrini, Arthur D. Riggs, and Guoping Fan
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4709–4714. doi: 10.1073/pnas.0712018105.
PMCID: PMC2290804
Transposition of a reconstructed Harbinger element in human cells and functional homology with two transposon-derived cellular genes
Ludivine Sinzelle, Vladimir V. Kapitonov, Dawid P. Grzela, Tobias Jursch, Jerzy Jurka, Zsuzsanna Izsvák, and Zoltán Ivics
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4715–4720. doi: 10.1073/pnas.0707746105.
PMCID: PMC2290759
Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1α and oxidative phosphorylation
Zoltan Arany, Bridget K. Wagner, Yanhong Ma, Jessica Chinsomboon, Dina Laznik, and Bruce M. Spiegelman
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4721–4726. doi: 10.1073/pnas.0800979105.
PMCID: PMC2290788
Protein phosphatase 2A controls the activity of histone deacetylase 7 during T cell apoptosis and angiogenesis
Maud Martin, Michael Potente, Veerle Janssens, Didier Vertommen, Jean-Claude Twizere, Mark H. Rider, Jozef Goris, Stefanie Dimmeler, Richard Kettmann, and Franck Dequiedt
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4727–4732. doi: 10.1073/pnas.0708455105.
PMCID: PMC2290748
Splicing mediates the activity of four putative cellular internal ribosome entry sites
Brian T. Baranick, Nathan A. Lemp, Jill Nagashima, Kei Hiraoka, Noriyuki Kasahara, and Christopher R. Logg
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4733–4738. doi: 10.1073/pnas.0710650105.
PMCID: PMC2290820
Inositol trisphosphate 3-kinase B (InsP3KB) as a physiological modulator of myelopoiesis
Yonghui Jia, Fabien Loison, Hidenori Hattori, Yitang Li, Christophe Erneux, Shin-Young Park, Chong Gao, Li Chai, Leslie E. Silberstein, Stephane Schurmans, and Hongbo R. Luo
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4739–4744. doi: 10.1073/pnas.0800218105.
PMCID: PMC2290809
PHDs overactivation during chronic hypoxia “desensitizes” HIFα and protects cells from necrosis
Amandine Ginouvès, Karine Ilc, Nuria Macías, Jacques Pouysségur, and Edurne Berra
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4745–4750. doi: 10.1073/pnas.0705680105.
PMCID: PMC2290777
Heparan sulfate biosynthesis enzymes EXT1 and EXT2 affect NDST1 expression and heparan sulfate sulfation
Jenny Presto, Maria Thuveson, Pernilla Carlsson, Marta Busse, Maria Wilén, Inger Eriksson, Marion Kusche-Gullberg, and Lena Kjellén
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4751–4756. doi: 10.1073/pnas.0705807105.
PMCID: PMC2290785
ATP-dependent activation of p21WAF1/CIP1-associated Cdk2 by Cdc6
Qiuming Kan, Shigeki Jinno, Hanako Yamamoto, Kohei Kobayashi, and Hiroto Okayama
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4757–4762. doi: 10.1073/pnas.0706392105.
PMCID: PMC2290776
Developmental Biology
Zebrafish early cardiac connexin, Cx36.7/Ecx, regulates myofibril orientation and heart morphogenesis by establishing Nkx2.5 expression
Naznin Sultana, Kakon Nag, Kazuyuki Hoshijima, Dale W. Laird, Atsushi Kawakami, and Shigehisa Hirose
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4763–4768. doi: 10.1073/pnas.0708451105.
PMCID: PMC2290751
Ecology
The lost origin of chemical ecology in the late 19th century
Thomas Hartmann
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4541–4546. doi: 10.1073/pnas.0709231105.
PMCID: PMC2290813
Herbivory-induced changes in the small-RNA transcriptome and phytohormone signaling in Nicotiana attenuata
Shree P. Pandey, Priyanka Shahi, Klaus Gase, and Ian T. Baldwin
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4559–4564. doi: 10.1073/pnas.0711363105.
PMCID: PMC2290812
Context- and scale-dependent effects of floral CO2 on nectar foraging by Manduca sexta
Joaquín Goyret, Poppy M. Markwell, and Robert A. Raguso
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4565–4570. doi: 10.1073/pnas.0708629105.
PMCID: PMC2290757
Seed odor mediates an obligate ant–plant mutualism in Amazonian rainforests
Elsa Youngsteadt, Satoshi Nojima, Christopher Häberlein, Stefan Schulz, and Coby Schal
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4571–4575. doi: 10.1073/pnas.0708643105.
PMCID: PMC2290770
From the Cover: Chemical Ecology Special Feature:
Evidence for olfactory search in wandering albatross, Diomedea exulans
Gabrielle A. Nevitt, Marcel Losekoot, and Henri Weimerskirch
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4576–4581. doi: 10.1073/pnas.0709047105.
PMCID: PMC2290754
Factors promoting marine invasions: A chemoecological approach
Ernesto Mollo, Margherita Gavagnin, Marianna Carbone, Francesco Castelluccio, Ferdinando Pozone, Vassilios Roussis, José Templado, Michael T. Ghiselin, and Guido Cimino
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4582–4586. doi: 10.1073/pnas.0709355105.
PMCID: PMC2290762
Evolution of polyketide synthases in bacteria
Christian P. Ridley, Ho Young Lee, and Chaitan Khosla
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4595–4600. doi: 10.1073/pnas.0710107105.
PMCID: PMC2290765
Mapping H5N1 highly pathogenic avian influenza risk in Southeast Asia
Marius Gilbert, Xiangming Xiao, Dirk U. Pfeiffer, M. Epprecht, Stephen Boles, Christina Czarnecki, Prasit Chaitaweesub, Wantanee Kalpravidh, Phan Q. Minh, M. J. Otte, Vincent Martin, and Jan Slingenbergh
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4769–4774. doi: 10.1073/pnas.0710581105.
PMCID: PMC2290786
Environmental Sciences
Photosynthetic maximum quantum yield increases are an essential component of the Southern Ocean phytoplankton response to iron
Michael R. Hiscock, Veronica P. Lance, Amy M. Apprill, Robert R. Bidigare, Zackary I. Johnson, B. Greg Mitchell, Walker O. Smith, Jr., and Richard T. Barber
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4775–4780. doi: 10.1073/pnas.0705006105.
PMCID: PMC2290768
Evolution
Selection for chemical trait remixing in an invasive weed after reassociation with a coevolved specialist
A. R. Zangerl, M. C. Stanley, and M. R. Berenbaum
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4547–4552. doi: 10.1073/pnas.0710280105.
PMCID: PMC2290761
Evolution of malaria parasite plastid targeting sequences
Christopher J. Tonkin, Bernardo J. Foth, Stuart A. Ralph, Nicole Struck, Alan F. Cowman, and Geoffrey I. McFadden
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4781–4785. doi: 10.1073/pnas.0707827105.
PMCID: PMC2290815
Increasing morphological complexity in multiple parallel lineages of the Crustacea
Sarah J. Adamowicz, Andy Purvis, and Matthew A. Wills
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4786–4791. doi: 10.1073/pnas.0709378105.
PMCID: PMC2290764
Rapid large-scale evolutionary divergence in morphology and performance associated with exploitation of a different dietary resource
Anthony Herrel, Katleen Huyghe, Bieke Vanhooydonck, Thierry Backeljau, Karin Breugelmans, Irena Grbac, Raoul Van Damme, and Duncan J. Irschick
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4792–4795. doi: 10.1073/pnas.0711998105.
PMCID: PMC2290806
Immunology
HDAC inhibitor reduces cytokine storm and facilitates induction of chimerism that reverses lupus in anti-CD3 conditioning regimen
Nainong Li, Dongchang Zhao, Mark Kirschbaum, Chunyan Zhang, Chia-Lei Lin, Ivan Todorov, Fouad Kandeel, Stephen Forman, and Defu Zeng
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4796–4801. doi: 10.1073/pnas.0712051105.
PMCID: PMC2290749
Maintenance of the plasma cell pool is independent of memory B cells
Anupama Ahuja, Shannon M. Anderson, Ashraf Khalil, and Mark J. Shlomchik
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4802–4807. doi: 10.1073/pnas.0800555105.
PMCID: PMC2290811
Role of the Akt pathway in mRNA translation of interferon-stimulated genes
Surinder Kaur, Antonella Sassano, Blazej Dolniak, Sonali Joshi, Beata Majchrzak-Kita, Darren P. Baker, Nissim Hay, Eleanor N. Fish, and Leonidas C. Platanias
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4808–4813. doi: 10.1073/pnas.0710907105.
PMCID: PMC2290753
Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria
Gabriele S. V. Campanella, Andrew M. Tager, Joseph K. El Khoury, Seddon Y. Thomas, Tabitha A. Abrazinski, Lindsay A. Manice, Richard A. Colvin, and Andrew D. Luster
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4814–4819. doi: 10.1073/pnas.0801544105.
PMCID: PMC2290783
Medical Sciences
Incremental parameter evaluation from incomplete data with application to the population pharmacology of anticoagulants
Marcel O. Vlad, Alexandru Dan Corlan, Federico Morán, Peter Oefner, and John Ross
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4627–4632. doi: 10.1073/pnas.0711508105.
PMCID: PMC2290818
X-chromosome inactivation and epigenetic fluidity in human embryonic stem cells
Susana S. Silva, Rebecca K. Rowntree, Shila Mekhoubad, and Jeannie T. Lee
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4820–4825. doi: 10.1073/pnas.0712136105.
PMCID: PMC2290799
Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia
Lan Wang, Guang-Biao Zhou, Ping Liu, Jun-Hong Song, Yang Liang, Xiao-Jing Yan, Fang Xu, Bing-Shun Wang, Jian-Hua Mao, Zhi-Xiang Shen, Sai-Juan Chen, and Zhu Chen
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4826–4831. doi: 10.1073/pnas.0712365105.
PMCID: PMC2290784
Decay dynamics of HIV-1 depend on the inhibited stages of the viral life cycle
Ahmad R. Sedaghat, Jason B. Dinoso, Lin Shen, Claus O. Wilke, and Robert F. Siliciano
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4832–4837. doi: 10.1073/pnas.0711372105.
PMCID: PMC2290747
Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2
Yoshinori Abe, Eri Oda-Sato, Kei Tobiume, Keiko Kawauchi, Yoichi Taya, Koji Okamoto, Moshe Oren, and Nobuyuki Tanaka
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4838–4843. doi: 10.1073/pnas.0712216105.
PMCID: PMC2290789
Cytosine methylation profiling of cancer cell lines
Mathias Ehrich, Julia Turner, Peter Gibbs, Lara Lipton, Mara Giovanneti, Charles Cantor, and Dirk van den Boom
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4844–4849. doi: 10.1073/pnas.0712251105.
PMCID: PMC2290817
Netrin-1 expression confers a selective advantage for tumor cell survival in metastatic breast cancer
Julien Fitamant, Céline Guenebeaud, Marie-May Coissieux, Catherine Guix, Isabelle Treilleux, Jean-Yves Scoazec, Thomas Bachelot, Agnès Bernet, and Patrick Mehlen
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4850–4855. doi: 10.1073/pnas.0709810105.
PMCID: PMC2290782
Linking Notch signaling to ischemic stroke
Joseph F. Arboleda-Velasquez, Zhipeng Zhou, Hwa Kyoung Shin, Angeliki Louvi, Hyung-Hwan Kim, Sean I. Savitz, James K. Liao, Salvatore Salomone, Cenk Ayata, Michael A. Moskowitz, and Spyros Artavanis-Tsakonas
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4856–4861. doi: 10.1073/pnas.0709867105.
PMCID: PMC2290794
Activation of Trk neurotrophin receptors by glucocorticoids provides a neuroprotective effect
Freddy Jeanneteau, Michael J. Garabedian, and Moses V. Chao
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4862–4867. doi: 10.1073/pnas.0709102105.
PMCID: PMC2290769
Microbiology
From the Cover:
Variation in virulence among clades of Escherichia coli O157:H7 associated with disease outbreaks
Shannon D. Manning, Alifiya S. Motiwala, A. Cody Springman, Weihong Qi, David W. Lacher, Lindsey M. Ouellette, Janice M. Mladonicky, Patricia Somsel, James T. Rudrik, Stephen E. Dietrich, Wei Zhang, Bala Swaminathan, David Alland, and Thomas S. Whittam
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4868–4873. doi: 10.1073/pnas.0710834105.
PMCID: PMC2290780
RXLR effector reservoir in two Phytophthora species is dominated by a single rapidly evolving superfamily with more than 700 members
Rays H. Y. Jiang, Sucheta Tripathy, Francine Govers, and Brett M. Tyler
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4874–4879. doi: 10.1073/pnas.0709303105.
PMCID: PMC2290801
Temperature-induced switch to the pathogenic yeast form of Histoplasma capsulatum requires Ryp1, a conserved transcriptional regulator
Van Q. Nguyen and Anita Sil
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4880–4885. doi: 10.1073/pnas.0710448105.
PMCID: PMC2290814
Rifamycin antibiotic resistance by ADP-ribosylation: Structure and diversity of Arr
Jennifer Baysarowich, Kalinka Koteva, Donald W. Hughes, Linda Ejim, Emma Griffiths, Kun Zhang, Murray Junop, and Gerard D. Wright
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4886–4891. doi: 10.1073/pnas.0711939105.
PMCID: PMC2290778
Neuroscience
Ischemic preconditioning blocks BAD translocation, Bcl-xL cleavage, and large channel activity in mitochondria of postischemic hippocampal neurons
Takahiro Miyawaki, Toshihiro Mashiko, Dimitry Ofengeim, Richard J. Flannery, Kyung-Min Noh, Sho Fujisawa, Laura Bonanni, Michael V. L. Bennett, R. Suzanne Zukin, and Elizabeth A. Jonas
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4892–4897. doi: 10.1073/pnas.0800628105.
PMCID: PMC2290755
Light deprivation damages monoamine neurons and produces a depressive behavioral phenotype in rats
M. M. C. Gonzalez and G. Aston-Jones
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4898–4903. doi: 10.1073/pnas.0703615105.
PMCID: PMC2290795
Chemical transmission between dopaminergic neuron pairs
Marie Vandecasteele, Jacques Glowinski, Jean-Michel Deniau, and Laurent Venance
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4904–4909. doi: 10.1073/pnas.0703121105.
PMCID: PMC2290772
Motion vision is independent of color in Drosophila
Satoko Yamaguchi, Reinhard Wolf, Claude Desplan, and Martin Heisenberg
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4910–4915. doi: 10.1073/pnas.0711484105.
PMCID: PMC2290790
Loss of the inactive myotubularin-related phosphatase Mtmr13 leads to a Charcot–Marie–Tooth 4B2-like peripheral neuropathy in mice
Fred L. Robinson, Ingrid R. Niesman, Kristina K. Beiswenger, and Jack E. Dixon
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4916–4921. doi: 10.1073/pnas.0800742105.
PMCID: PMC2290800
Vesicle association and exocytosis at ribbon and extraribbon sites in retinal bipolar cell presynaptic terminals
David Zenisek
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4922–4927. doi: 10.1073/pnas.0709067105.
PMCID: PMC2290766
Plant Biology
cis-Jasmone induces Arabidopsis genes that affect the chemical ecology of multitrophic interactions with aphids and their parasitoids
Toby J. A. Bruce, Michaela C. Matthes, Keith Chamberlain, Christine M. Woodcock, Abdul Mohib, Ben Webster, Lesley E. Smart, Michael A. Birkett, John A. Pickett, and Johnathan A. Napier
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4553–4558. doi: 10.1073/pnas.0710305105.
PMCID: PMC2290791
From the Cover:
SymRK defines a common genetic basis for plant root endosymbioses with arbuscular mycorrhiza fungi, rhizobia, and Frankiabacteria
Hassen Gherbi, Katharina Markmann, Sergio Svistoonoff, Joan Estevan, Daphné Autran, Gabor Giczey, Florence Auguy, Benjamin Péret, Laurent Laplaze, Claudine Franche, Martin Parniske, and Didier Bogusz
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4928–4932. doi: 10.1073/pnas.0710618105.
PMCID: PMC2290763
Three thioredoxin targets in the inner envelope membrane of chloroplasts function in protein import and chlorophyll metabolism
Sandra Bartsch, Julie Monnet, Kristina Selbach, Françoise Quigley, John Gray, Diter von Wettstein, Steffen Reinbothe, and Christiane Reinbothe
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4933–4938. doi: 10.1073/pnas.0800378105.
PMCID: PMC2290756
Systems approach identifies an organic nitrogen-responsive gene network that is regulated by the master clock control gene CCA1
Rodrigo A. Gutiérrez, Trevor L. Stokes, Karen Thum, Xiaodong Xu, Mariana Obertello, Manpreet S. Katari, Milos Tanurdzic, Alexis Dean, Damion C. Nero, C. Robertson McClung, and Gloria M. Coruzzi
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4939–4944. doi: 10.1073/pnas.0800211105.
PMCID: PMC2290744
Involvement of Arabidopsis HOS15 in histone deacetylation and cold tolerance
Jianhua Zhu, Jae Cheol Jeong, Yanmei Zhu, Irina Sokolchik, Saori Miyazaki, Jian-Kang Zhu, Paul M. Hasegawa, Hans J. Bohnert, Huazhong Shi, Dae-Jin Yun, and Ray A. Bressan
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4945–4950. doi: 10.1073/pnas.0801029105.
PMCID: PMC2290775
Genome-wide analysis for discovery of rice microRNAs reveals natural antisense microRNAs (nat-miRNAs)
Cheng Lu, Dong-Hoon Jeong, Karthik Kulkarni, Manoj Pillay, Kan Nobuta, Rana German, Shawn R. Thatcher, Christopher Maher, Lifang Zhang, Doreen Ware, Bin Liu, Xiaofeng Cao, Blake C. Meyers, and Pamela J. Green
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4951–4956. doi: 10.1073/pnas.0708743105.
PMCID: PMC2290808
Population Biology
Population genomics of the wild yeast Saccharomyces paradoxus: Quantifying the life cycle
Isheng J. Tsai, Douda Bensasson, Austin Burt, and Vassiliki Koufopanou
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4957–4962. doi: 10.1073/pnas.0707314105.
PMCID: PMC2290798
Social Sciences
Environmental Sciences
Modeling targeted layered containment of an influenza pandemic in the United States
M. Elizabeth Halloran, Neil M. Ferguson, Stephen Eubank, Ira M. Longini, Jr., Derek A. T. Cummings, Bryan Lewis, Shufu Xu, Christophe Fraser, Anil Vullikanti, Timothy C. Germann, Diane Wagener, Richard Beckman, Kai Kadau, Chris Barrett, Catherine A. Macken, Donald S. Burke, and Philip Cooley
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4639–4644. doi: 10.1073/pnas.0706849105.
PMCID: PMC2290797
Social Sciences
Tracing information flow on a global scale using Internet chain-letter data
David Liben-Nowell and Jon Kleinberg
Proc Natl Acad Sci U S A. 2008 March 25; 105(12): 4633–4638. doi: 10.1073/pnas.0708471105.
PMCID: PMC2290760
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