| | This journal provides immediate access to some articles. Inaugural Article Histone arginine methylation is required for vernalization-induced epigenetic silencing of FLC in winter-annual Arabidopsis thaliana Robert J. Schmitz, Sibum Sung, and Richard M. Amasino PMCID: PMC2206549 Letters Ancient lineages in the genome: A response to Fagundes et al. Daniel Garrigan and Michael F. Hammer PMCID: PMC2206625 Reply to Garrigan and Hammer: Ancient lineages and assimilation Nelson J. R. Fagundes, Nicolas Ray, Mark Beaumont, Samuel Neuenschwander, Francisco M. Salzano, Sandro L. Bonatto, and Laurent Excoffier PMCID: PMC2206626 This Week in PNAS Proc Natl Acad Sci U S A. 2008 January 15; 105(2): 401–402. doi: 10.1073/iti0208105.PMCID: PMC2206544 Commentaries Heme–copper oxidases use tunneling pathways David N. Beratan and Ilya A. Balabin PMCID: PMC2206545 Alternative endings James E. Haber PMCID: PMC2206546 Linkages between CO2, climate, and evolution in deep time Dana L. Royer PMCID: PMC2206547 Thyroid mimetic as an option for lowering low-density lipoprotein Scott M. Grundy PMCID: PMC2206548 Physical Sciences Applied Physical Sciences Noise in solid-state nanopores R. M. M. Smeets, U. F. Keyser, N. H. Dekker, and C. Dekker PMCID: PMC2206550 Single-shot detection of bacterial endospores via coherent Raman spectroscopy Dmitry Pestov, Xi Wang, Gombojav O. Ariunbold, Robert K. Murawski, Vladimir A. Sautenkov, Arthur Dogariu, Alexei V. Sokolov, and Marlan O. Scully PMCID: PMC2206551 Instability in pipe flow D. L. Cotrell, G. B. McFadden, and B. J. Alder PMCID: PMC2206552 Chemistry Domain requirement of moenomycin binding to bifunctional transglycosylases and development of high-throughput discovery of antibiotics Ting-Jen Rachel Cheng, Ming-Ta Sung, Hsin-Yu Liao, Yi-Fan Chang, Chia-Wei Chen, Chia-Ying Huang, Lien-Yang Chou, Yen-Da Wu, Yin-Hsuan Chen, Yih-Shyun E. Cheng, Chi-Huey Wong, Che Ma, and Wei-Chieh Cheng PMCID: PMC2206553 Temperature dependence of the two-dimensional infrared spectrum of liquid H2O D. Kraemer, M. L. Cowan, A. Paarmann, N. Huse, E. T. J. Nibbering, T. Elsaesser, and R. J. Dwayne Miller PMCID: PMC2206554 Nanoelectrochemistry of mammalian cells Peng Sun, François O. Laforge, Thushara P. Abeyweera, Susan A. Rotenberg, James Carpino, and Michael V. Mirkin PMCID: PMC2206555 Preferred side-chain constellations at antiparallel coiled-coil interfaces Erik B. Hadley, Oliver D. Testa, Derek N. Woolfson, and Samuel H. Gellman PMCID: PMC2206570 Geology From the Cover:
The impact of Miocene atmospheric carbon dioxide fluctuations on climate and the evolution of terrestrial ecosystems Wolfram M. Kürschner, Zlatko Kvaček, and David L. Dilcher PMCID: PMC2206556 Geophysics Climate forcing from the transport sectors Jan Fuglestvedt, Terje Berntsen, Gunnar Myhre, Kristin Rypdal, and Ragnhild Bieltvedt Skeie PMCID: PMC2206557 Physics Anomalous dynamics of cell migration Peter Dieterich, Rainer Klages, Roland Preuss, and Albrecht Schwab PMCID: PMC2206558 Biological Sciences Agricultural Sciences Net energy of cellulosic ethanol from switchgrass M. R. Schmer, K. P. Vogel, R. B. Mitchell, and R. K. Perrin PMCID: PMC2206559 A crop population perspective on maize seed systems in Mexico George A. Dyer and J. Edward Taylor PMCID: PMC2206560 Applied Biological Sciences Domain requirement of moenomycin binding to bifunctional transglycosylases and development of high-throughput discovery of antibiotics Ting-Jen Rachel Cheng, Ming-Ta Sung, Hsin-Yu Liao, Yi-Fan Chang, Chia-Wei Chen, Chia-Ying Huang, Lien-Yang Chou, Yen-Da Wu, Yin-Hsuan Chen, Yih-Shyun E. Cheng, Chi-Huey Wong, Che Ma, and Wei-Chieh Cheng PMCID: PMC2206553 Ultrafast DNA sequencing on a microchip by a hybrid separation mechanism that gives 600 bases in 6.5 minutes Christopher P. Fredlake, Daniel G. Hert, Cheuk-Wai Kan, Thomas N. Chiesl, Brian E. Root, Ryan E. Forster, and Annelise E. Barron PMCID: PMC2206561 Biochemistry Assembly of Weibel–Palade body-like tubules from N-terminal domains of von Willebrand factor Ren-Huai Huang, Ying Wang, Robyn Roth, Xiong Yu, Angie R. Purvis, John E. Heuser, Edward H. Egelman, and J. Evan Sadler PMCID: PMC2206562 Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide Norio Kudo, Keigo Kumagai, Nario Tomishige, Toshiyuki Yamaji, Soichi Wakatsuki, Masahiro Nishijima, Kentaro Hanada, and Ryuichi Kato PMCID: PMC2206563 Biosynthesis of the enediyne antitumor antibiotic C-1027 involves a new branching point in chorismate metabolism Steven G. Van Lanen, Shuangjun Lin, and Ben Shen PMCID: PMC2206564 Cross-crystal averaging reveals that the structure of the peptidyl-transferase center is the same in the 70S ribosome and the 50S subunit Miljan Simonović and Thomas A. Steitz PMCID: PMC2206565 Allosteric cooperativity in protein kinase A Larry R. Masterson, Alessandro Mascioni, Nathaniel J. Traaseth, Susan S. Taylor, and Gianluigi Veglia PMCID: PMC2206566 In vitro reconstitution of the human RISC-loading complex Ian J. MacRae, Enbo Ma, Min Zhou, Carol V. Robinson, and Jennifer A. Doudna PMCID: PMC2206567 Discovery of an alternate metabolic pathway for urea synthesis in adult Aedes aegypti mosquitoes Patricia Y. Scaraffia, Guanhong Tan, Jun Isoe, Vicki H. Wysocki, Michael A. Wells, and Roger L. Miesfeld PMCID: PMC2206568 D-loop formation by Brh2 protein of Ustilago maydis Nayef Mazloum, Qingwen Zhou, and William K. Holloman PMCID: PMC2206569 Biophysics Noise in solid-state nanopores R. M. M. Smeets, U. F. Keyser, N. H. Dekker, and C. Dekker PMCID: PMC2206550 Anomalous dynamics of cell migration Peter Dieterich, Rainer Klages, Roland Preuss, and Albrecht Schwab PMCID: PMC2206558 Preferred side-chain constellations at antiparallel coiled-coil interfaces Erik B. Hadley, Oliver D. Testa, Derek N. Woolfson, and Samuel H. Gellman PMCID: PMC2206570 Multiscale complex network of protein conformational fluctuations in single-molecule time series Chun-Biu Li, Haw Yang, and Tamiki Komatsuzaki PMCID: PMC2206571 Conformational changes of calmodulin upon Ca2+ binding studied with a microfluidic mixer Hye Yoon Park, Sally A. Kim, Jonas Korlach, Elizabeth Rhoades, Lisa W. Kwok, Warren R. Zipfel, M. Neal Waxham, Watt W. Webb, and Lois Pollack PMCID: PMC2206572 Cooperative binding of ATP and RNA induces a closed conformation in a DEAD box RNA helicase Bettina Theissen, Anne R. Karow, Jürgen Köhler, Airat Gubaev, and Dagmar Klostermeier PMCID: PMC2206573 Developmental Biology Heat-shock protein 90α1 is required for organized myofibril assembly in skeletal muscles of zebrafish embryos Shao Jun Du, Huiqing Li, Yuehong Bian, and Yongwang Zhong PMCID: PMC2206574 Ecology Food limitation leads to behavioral diversification and dietary specialization in sea otters M. Tim Tinker, Gena Bentall, and James A. Estes PMCID: PMC2206575 Ecological rules governing helminth–microparasite coinfection Andrea L. Graham PMCID: PMC2206576 Water shrews detect movement, shape, and smell to find prey underwater Kenneth C. Catania, James F. Hare, and Kevin L. Campbell PMCID: PMC2206577 Interaction location outweighs the competitive advantage of numerical superiority in Cebus capucinus intergroup contests Margaret C. Crofoot, Ian C. Gilby, Martin C. Wikelski, and Roland W. Kays PMCID: PMC2206578 Environmental Sciences Single-shot detection of bacterial endospores via coherent Raman spectroscopy Dmitry Pestov, Xi Wang, Gombojav O. Ariunbold, Robert K. Murawski, Vladimir A. Sautenkov, Arthur Dogariu, Alexei V. Sokolov, and Marlan O. Scully PMCID: PMC2206551 Evolution From the Cover:
Sexual maturity in growing dinosaurs does not fit reptilian growth models Andrew H. Lee and Sarah Werning PMCID: PMC2206579 Phylogeny of endocytic components yields insight into the process of nonendosymbiotic organelle evolution Joel B. Dacks, Pak P. Poon, and Mark C. Field PMCID: PMC2206580 Interactions between the direct and indirect effects of predators determine life history evolution in a killifish Matthew R. Walsh and David N. Reznick PMCID: PMC2206581 Isotopic evidence for omnivory among European cave bears: Late Pleistocene Ursus spelaeus from the Peştera cu Oase, Romania Michael P. Richards, Martina Pacher, Mathias Stiller, Jérôme Quilès, Michael Hofreiter, Silviu Constantin, João Zilhão, and Erik Trinkaus PMCID: PMC2206582 Genetics Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location Carole Yauk, Aris Polyzos, Andrea Rowan-Carroll, Christopher M. Somers, Roger W. Godschalk, Frederik J. Van Schooten, M. Lynn Berndt, Igor P. Pogribny, Igor Koturbash, Andrew Williams, George R. Douglas, and Olga Kovalchuk PMCID: PMC2206583 Hydrogen peroxide scavenging rescues frataxin deficiency in a Drosophila model of Friedreich's ataxia Peter R. Anderson, Kim Kirby, William C. Orr, Arthur J. Hilliker, and John P. Phillips PMCID: PMC2206584 Required sample size and nonreplicability thresholds for heterogeneous genetic associations Ramal Moonesinghe, Muin J. Khoury, Tiebin Liu, and John P. A. Ioannidis PMCID: PMC2206585 Immunology A safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer Elisa Kieback, Jehad Charo, Daniel Sommermeyer, Thomas Blankenstein, and Wolfgang Uckert PMCID: PMC2206586 Platelets prevent IFN-α/β-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus Matteo Iannacone, Giovanni Sitia, Masanori Isogawa, Jason K. Whitmire, Patrizia Marchese, Francis V. Chisari, Zaverio M. Ruggeri, and Luca G. Guidotti PMCID: PMC2206587 Evolution of GITRL immune function: Murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily Kausik Chattopadhyay, Udupi A. Ramagopal, Michael Brenowitz, Stanley G. Nathenson, and Steven C. Almo PMCID: PMC2206588 Structural basis for ligand-mediated mouse GITR activation Zhaocai Zhou, Yukiko Tone, Xiaomin Song, Keiji Furuuchi, James D. Lear, Herman Waldmann, Masahide Tone, Mark I. Greene, and Ramachandran Murali PMCID: PMC2206589 Functional deficit of T regulatory cells in Fulani, an ethnic group with low susceptibility to Plasmodium falciparum malaria Maria G. Torcia, Veronica Santarlasci, Lorenzo Cosmi, AnnMaria Clemente, Laura Maggi, Valentina D. Mangano, Federica Verra, Germana Bancone, Issa Nebie, Bienvenu Sodiomon Sirima, Francesco Liotta, Francesca Frosali, Roberta Angeli, Carlo Severini, Anna R. Sannella, Paolo Bonini, Maria Lucibello, Enrico Maggi, Enrico Garaci, Mario Coluzzi, Federico Cozzolino, Francesco Annunziato, Sergio Romagnani, and David Modiano PMCID: PMC2206590 Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis Jeremy B. Swann, Matthew D. Vesely, Anabel Silva, Janelle Sharkey, Shizuo Akira, Robert D. Schreiber, and Mark J. Smyth PMCID: PMC2206591 Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism Jens Derbinski, Sheena Pinto, Stefanie Rösch, Klaus Hexel, and Bruno Kyewski PMCID: PMC2206592 Medical Sciences From the Cover:
The thyroid hormone mimetic compound KB2115 lowers plasma LDL cholesterol and stimulates bile acid synthesis without cardiac effects in humans Anders Berkenstam, Jens Kristensen, Karin Mellström, Bo Carlsson, Johan Malm, Stefan Rehnmark, Neeraj Garg, Carl Magnus Andersson, Mats Rudling, Folke Sjöberg, Bo Angelin, and John D. Baxter PMCID: PMC2206593 From the Cover:
Addressing the health benefits and risks, involving vitamin D or skin cancer, of increased sun exposure Johan Moan, Alina Carmen Porojnicu, Arne Dahlback, and Richard B. Setlow PMCID: PMC2206594 ICA512 signaling enhances pancreatic β-cell proliferation by regulating cyclins D through STATs Hassan Mziaut, Stephan Kersting, Klaus-Peter Knoch, Wan-Hung Fan, Mirko Trajkovski, Katja Erdmann, Hendrik Bergert, Florian Ehehalt, Hans-Detlev Saeger, and Michele Solimena PMCID: PMC2206595 Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and mast cells Stina Feltenmark, Narinder Gautam, Åsa Brunnström, William Griffiths, Linda Backman, Charlotte Edenius, Lennart Lindbom, Magnus Björkholm, and Hans-Erik Claesson PMCID: PMC2206596 Activation of the hypoxia-inducible factor-1α pathway accelerates bone regeneration Chao Wan, Shawn R. Gilbert, Ying Wang, Xuemei Cao, Xing Shen, Girish Ramaswamy, Kimberly A. Jacobsen, Zainab S. Alaql, Alan W. Eberhardt, Louis C. Gerstenfeld, Thomas A. Einhorn, Lianfu Deng, and Thomas L. Clemens PMCID: PMC2206597 Signaling networks assembled by oncogenic EGFR and c-Met Ailan Guo, Judit Villén, Jon Kornhauser, Kimberly A. Lee, Matthew P. Stokes, Klarisa Rikova, Anthony Possemato, Julie Nardone, Gregory Innocenti, Randall Wetzel, Yi Wang, Joan MacNeill, Jeffrey Mitchell, Steven P. Gygi, John Rush, Roberto D. Polakiewicz, and Michael J. Comb PMCID: PMC2206598 High field gradient targeting of magnetic nanoparticle-loaded endothelial cells to the surfaces of steel stents Boris Polyak, Ilia Fishbein, Michael Chorny, Ivan Alferiev, Darryl Williams, Ben Yellen, Gary Friedman, and Robert J. Levy PMCID: PMC2206599 Microbiology Differential response of the plant Medicago truncatula to its symbiont Sinorhizobium meliloti or an exopolysaccharide-deficient mutant Kathryn M. Jones, Natalya Sharopova, Dasharath P. Lohar, Jennifer Q. Zhang, Kathryn A. VandenBosch, and Graham C. Walker PMCID: PMC2206600 Role for lysosomal enzyme β-hexosaminidase in the control of mycobacteria infection Ingrid Chou Koo, Yamini M. Ohol, Ping Wu, J. Hiroshi Morisaki, Jeffery S. Cox, and Eric J. Brown PMCID: PMC2206601 Neuroscience Specific expression of long noncoding RNAs in the mouse brain Tim R. Mercer, Marcel E. Dinger, Susan M. Sunkin, Mark F. Mehler, and John S. Mattick PMCID: PMC2206602 High-frequency HTR3B variant associated with major depression dramatically augments the signaling of the human 5-HT3AB receptor Karen Krzywkowski, Paul A. Davies, Paula L. Feinberg-Zadek, Hans Bräuner-Osborne, and Anders A. Jensen PMCID: PMC2206603 Hypothesis-based RNAi screening identifies neuroprotective genes in a Parkinson's disease model Shusei Hamamichi, Renee N. Rivas, Adam L. Knight, Songsong Cao, Kim A. Caldwell, and Guy A. Caldwell PMCID: PMC2206604 On BC1 RNA and the fragile X mental retardation protein Anna Iacoangeli, Timofey S. Rozhdestvensky, Natalia Dolzhanskaya, Barthélémy Tournier, Janin Schütt, Jürgen Brosius, Robert B. Denman, Edouard W. Khandjian, Stefan Kindler, and Henri Tiedge PMCID: PMC2206605 Nogo receptor antagonizes p75NTR-dependent motor neuron death Luc Dupuis, Mariana Pehar, Patricia Cassina, Frédérique Rene, Raquel Castellanos, Caroline Rouaux, Mandi Gandelman, Leda Dimou, Martin E. Schwab, Jean-Philippe Loeffler, Luis Barbeito, and Jose-Luis Gonzalez de Aguilar PMCID: PMC2206606 Dendritic glutamate release produces autocrine activation of mGluR1 in cerebellar Purkinje cells Jung Hoon Shin, Yu Shin Kim, and David J. Linden PMCID: PMC2206607 IL-1β is an essential mediator of the antineurogenic and anhedonic effects of stress Ja Wook Koo and Ronald S. Duman PMCID: PMC2206608 Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis Claudio Hetz, Ann-Hwee Lee, Dennisse Gonzalez-Romero, Peter Thielen, Joaquín Castilla, Claudio Soto, and Laurie H. Glimcher PMCID: PMC2206609 The phosphorylation state of Ser-129 in human α-synuclein determines neurodegeneration in a rat model of Parkinson disease Oleg S. Gorbatyuk, Shoudong Li, Layla F. Sullivan, Weijun Chen, Galina Kondrikova, Fredric P. Manfredsson, Ronald J. Mandel, and Nicholas Muzyczka PMCID: PMC2206610 Learning-related long-term potentiation of inhibitory synapses in the cerebellar cortex Bibiana Scelfo, Benedetto Sacchetti, and Piergiorgio Strata PMCID: PMC2206611 Homeostatic regulation of AMPA receptor expression at single hippocampal synapses Qingming Hou, Dawei Zhang, Larissa Jarzylo, Richard L. Huganir, and Heng-Ye Man PMCID: PMC2206612 Rapid cell-cycle reentry and cell death after acute inactivation of the retinoblastoma gene product in postnatal cochlear hair cells Thomas Weber, Mary K. Corbett, Lionel M. L. Chow, Marcus B. Valentine, Suzanne J. Baker, and Jian Zuo PMCID: PMC2206613 Opioid neuropeptide genotypes in relation to heroin abuse: Dopamine tone contributes to reversed mesolimbic proenkephalin expression Andrej Nikoshkov, Katarina Drakenberg, Xinyu Wang, Monika Cs. Horvath, Eva Keller, and Yasmin L. Hurd PMCID: PMC2206614 Physiology The A2b adenosine receptor protects against vascular injury Dan Yang, Milka Koupenova, Donald J. McCrann, Katherine J. Kopeikina, Herbert M. Kagan, Barbara M. Schreiber, and Katya Ravid PMCID: PMC2206615 Plant Biology Histone arginine methylation is required for vernalization-induced epigenetic silencing of FLC in winter-annual Arabidopsis thaliana Robert J. Schmitz, Sibum Sung, and Richard M. Amasino PMCID: PMC2206549 Respiratory metabolism of illuminated leaves depends on CO2 and O2 conditions Guillaume Tcherkez, Richard Bligny, Elizabeth Gout, Aline Mahé, Michael Hodges, and Gabriel Cornic PMCID: PMC2206616 Cell-specific nitrogen responses mediate developmental plasticity Miriam L. Gifford, Alexis Dean, Rodrigo A. Gutierrez, Gloria M. Coruzzi, and Kenneth D. Birnbaum PMCID: PMC2206617 Psychology A predisposition for biological motion in the newborn baby Francesca Simion, Lucia Regolin, and Hermann Bulf PMCID: PMC2206618 From the Cover:
Binaural jitter improves interaural time-difference sensitivity of cochlear implantees at high pulse rates Bernhard Laback and Piotr Majdak PMCID: PMC2206619 Sustainability Science Difficulties in tracking the long-term global trend in tropical forest area Alan Grainger PMCID: PMC2206620 Corrections Correction for Chelur and Chalfie, Targeted cell killing by reconstituted caspases PMCID: PMC2206621 Corrects: Dattananda S. Chelur, et al. From the Cover:
Targeted cell killing by reconstituted caspases. Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2283–2288. Correction for Malone et al., Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism PMCID: PMC2206622 Corrects: Amanda M. D. Malone, et al. Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism. Proc Natl Acad Sci U S A. 2007 August 14; 104(33): 13325–13330. Correction for Zvaritch et al., An Ryr1I4895T mutation abolishes Ca2+ release channel function and delays development in homozygous offspring of a mutant mouse line PMCID: PMC2206623 Corrects: Elena Zvaritch, et al. An Ryr1I4895T mutation abolishes Ca2+ release channel function and delays development in homozygous offspring of a mutant mouse line. Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18537–18542. Correction for Drabsch et al., Mechanism of and requirement for estrogen-regulated MYB expression in estrogen-receptor-positive breast cancer cells PMCID: PMC2206624 Corrects: Yvette Drabsch, et al. Mechanism of and requirement for estrogen-regulated MYB expression in estrogen-receptor-positive breast cancer cells. Proc Natl Acad Sci U S A. 2007 August 21; 104(34): 13762–13767. |
