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Volume 104(10);  March 6, 2007
Biological Science
Plant Biology
Arabidopsis SNI1 and RAD51D regulate both gene transcription and DNA recombination during the defense response
Wendy E. Durrant, Shui Wang, and Xinnian Dong
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4223–4227. Published online 2007 February 21. doi: 10.1073/pnas.0609357104.
PMCID: PMC1820736
This Week in PNAS
In This Issue
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3669–3670. doi: 10.1073/iti1007104.
PMCID: PMC1820638
Commentaries
The role of evolution in the invasion process
Stephen J. Novak
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3671–3672. Published online 2007 February 28. doi: 10.1073/pnas.0700224104.
PMCID: PMC1820639
Meiosis in living color: Fluorescence-based tetrad analysis in Arabidopsis
R. Scott Hawley
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3673–3674. Published online 2007 February 28. doi: 10.1073/pnas.0700276104.
PMCID: PMC1820640
Biofortification of plant-based food: Enhancing folate levels by metabolic engineering
Dean DellaPenna
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3675–3676. Published online 2007 March 5. doi: 10.1073/pnas.0700640104.
PMCID: PMC1820641
Physical Sciences
Applied Mathematics
Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer
Matthew D. Johnston, Carina M. Edwards, Walter F. Bodmer, Philip K. Maini, and S. Jonathan Chapman
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4008–4013. Published online 2007 February 28. doi: 10.1073/pnas.0611179104.
PMCID: PMC1820699
Applied Physical Sciences
Predicting response to breast cancer neoadjuvant chemotherapy using diffuse optical spectroscopy
Albert Cerussi, David Hsiang, Natasha Shah, Rita Mehta, Amanda Durkin, John Butler, and Bruce J. Tromberg
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4014–4019. Published online 2007 February 28. doi: 10.1073/pnas.0611058104.
PMCID: PMC1805697
Chemistry
Antibody-catalyzed anaerobic destruction of methamphetamine
Yang Xu, Mark S. Hixon, Noboru Yamamoto, Laura A. McAllister, Anita D. Wentworth, Paul Wentworth, Jr., and Kim D. Janda
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3681–3686. Published online 2007 February 28. doi: 10.1073/pnas.0611094104.
PMCID: PMC1820643
Electrostatic gating of a nanometer water channel
Jingyuan Li, Xiaojing Gong, Hangjun Lu, Ding Li, Haiping Fang, and Ruhong Zhou
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3687–3692. Published online 2007 February 27. doi: 10.1073/pnas.0604541104.
PMCID: PMC1820644
A hexahistidine-Zn2+-dye label reveals STIM1 surface exposure
Christina T. Hauser and Roger Y. Tsien
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3693–3697. Published online 2007 February 28. doi: 10.1073/pnas.0611713104.
PMCID: PMC1805700
Mechanism of metal-independent decomposition of organic hydroperoxides and formation of alkoxyl radicals by halogenated quinones
Ben-Zhan Zhu, Hong-Tao Zhao, Balaraman Kalyanaraman, Jun Liu, Guo-Qiang Shan, Yu-Guo Du, and Balz Frei
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3698–3702. Published online 2007 February 28. doi: 10.1073/pnas.0605527104.
PMCID: PMC1820646
Gallium (III) triflate catalyzed efficient Strecker reaction of ketones and their fluorinated analogs
G. K. Surya Prakash, Thomas Mathew, Chiradeep Panja, Steevens Alconcel, Habiba Vaghoo, Clement Do, and George A. Olah
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3703–3706. Published online 2007 February 28. doi: 10.1073/pnas.0611316104.
PMCID: PMC1820647
Scanning tunneling microscopy of the formation, transformation, and property of oligothiophene self-organizations on graphite and gold surfaces
Zhi-Yong Yang, Hui-Min Zhang, Cun-Ji Yan, Shan-Shan Li, Hui-Juan Yan, Wei-Guo Song, and Li-Jun Wan
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3707–3712. Published online 2007 February 28. doi: 10.1073/pnas.0611585104.
PMCID: PMC1820648
Environmental Sciences
Solar influence on climate during the past millennium: Results from transient simulations with the NCAR Climate System Model
Caspar M. Ammann, Fortunat Joos, David S. Schimel, Bette L. Otto-Bliesner, and Robert A. Tomas
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3713–3718. Published online 2007 March 5. doi: 10.1073/pnas.0605064103.
PMCID: PMC1810336
Geophysics
Delayed upwelling alters nearshore coastal ocean ecosystems in the northern California current
John A. Barth, Bruce A. Menge, Jane Lubchenco, Francis Chan, John M. Bane, Anthony R. Kirincich, Margaret A. McManus, Karina J. Nielsen, Stephen D. Pierce, and Libe Washburn
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3719–3724. Published online 2007 February 27. doi: 10.1073/pnas.0700462104.
PMCID: PMC1805484
Mathematics
Lifting cusp forms to Maass forms with an application to partitions
Kathrin Bringmann and Ken Ono
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3725–3731. Published online 2007 February 28. doi: 10.1073/pnas.0611414104.
PMCID: PMC1820651
Physics
Experiments with probe masses
V. B. Braginsky
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3677–3680. Published online 2007 February 12. doi: 10.1073/pnas.0610311104.
PMCID: PMC1820642
Unified picture of the oxygen isotope effect in cuprate superconductors
Xiao-Jia Chen, Viktor V. Struzhkin, Zhigang Wu, Hai-Qing Lin, Russell J. Hemley, and Ho-kwang Mao
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3732–3735. Published online 2007 February 26. doi: 10.1073/pnas.0611473104.
PMCID: PMC1820652
On the mechanism of wing size determination in fly development
Lars Hufnagel, Aurelio A. Teleman, Hervé Rouault, Stephen M. Cohen, and Boris I. Shraiman
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3835–3840. Published online 2007 February 28. doi: 10.1073/pnas.0607134104.
PMCID: PMC1820670
Biological Sciences
Anthropology
Absence of the lactase-persistence-associated allele in early Neolithic Europeans
J. Burger, M. Kirchner, B. Bramanti, W. Haak, and M. G. Thomas
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3736–3741. Published online 2007 February 28. doi: 10.1073/pnas.0607187104.
PMCID: PMC1820653
Applied Biological Sciences
RNA aptamers directed to discrete functional sites on a single protein structural domain
Hua Shi, Xiaochun Fan, Aarti Sevilimedu, and John T. Lis
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3742–3746. Published online 2007 February 28. doi: 10.1073/pnas.0607805104.
PMCID: PMC1820654
Induction of the celC operon of Clostridium thermocellum by laminaribiose
Michael Newcomb, Chun-Yu Chen, and J. H. David Wu
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3747–3752. Published online 2007 February 27. doi: 10.1073/pnas.0700087104.
PMCID: PMC1820655
Biochemistry
Antibody-catalyzed anaerobic destruction of methamphetamine
Yang Xu, Mark S. Hixon, Noboru Yamamoto, Laura A. McAllister, Anita D. Wentworth, Paul Wentworth, Jr., and Kim D. Janda
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3681–3686. Published online 2007 February 28. doi: 10.1073/pnas.0611094104.
PMCID: PMC1820643
Mechanism for inactivation of the mitotic inhibitory kinase Wee1 at M phase
Kengo Okamoto and Noriyuki Sagata
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3753–3758. Published online 2007 February 23. doi: 10.1073/pnas.0607357104.
PMCID: PMC1820656
Structures of the extracellular regions of the group II/III metabotropic glutamate receptors
Takanori Muto, Daisuke Tsuchiya, Kosuke Morikawa, and Hisato Jingami
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3759–3764. Published online 2007 February 26. doi: 10.1073/pnas.0611577104.
PMCID: PMC1820657
Regulation of poly(ADP-ribose) polymerase 1 activity by the phosphorylation state of the nuclear NAD biosynthetic enzyme NMN adenylyl transferase 1
Felicitas Berger, Corinna Lau, and Mathias Ziegler
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3765–3770. Published online 2007 February 22. doi: 10.1073/pnas.0609211104.
PMCID: PMC1820658
Inhibition of regulated proteolysis by RseB
Brent O. Cezairliyan and Robert T. Sauer
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3771–3776. Published online 2007 February 26. doi: 10.1073/pnas.0611567104.
PMCID: PMC1820659
Biophysics
Electrostatic gating of a nanometer water channel
Jingyuan Li, Xiaojing Gong, Hangjun Lu, Ding Li, Haiping Fang, and Ruhong Zhou
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3687–3692. Published online 2007 February 27. doi: 10.1073/pnas.0604541104.
PMCID: PMC1820644
Direct visualization of Escherichia coli chemotaxis receptor arrays using cryo-electron microscopy
Peijun Zhang, Cezar M. Khursigara, Lisa M. Hartnell, and Sriram Subramaniam
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3777–3781. Published online 2007 February 26. doi: 10.1073/pnas.0610106104.
PMCID: PMC1820660
Adhesion mechanisms of the mussel foot proteins mfp-1 and mfp-3
Qi Lin, Delphine Gourdon, Chengjun Sun, Niels Holten-Andersen, Travers H. Anderson, J. Herbert Waite, and Jacob N. Israelachvili
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3782–3786. Published online 2007 February 28. doi: 10.1073/pnas.0607852104.
PMCID: PMC1820661
Cell Biology
A hexahistidine-Zn2+-dye label reveals STIM1 surface exposure
Christina T. Hauser and Roger Y. Tsien
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3693–3697. Published online 2007 February 28. doi: 10.1073/pnas.0611713104.
PMCID: PMC1805700
Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis
Tobias Schmelzle, Arnaud A. Mailleux, Michael Overholtzer, Jason S. Carroll, Nicole L. Solimini, Eric S. Lightcap, Ole P. Veiby, and Joan S. Brugge
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3787–3792. Published online 2007 February 26. doi: 10.1073/pnas.0700115104.
PMCID: PMC1820662
Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate
Roberto Zoncu, Rushika M. Perera, Rafael Sebastian, Fubito Nakatsu, Hong Chen, Tamas Balla, Guillermo Ayala, Derek Toomre, and Pietro V. De Camilli
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3793–3798. Published online 2007 February 27. doi: 10.1073/pnas.0611733104.
PMCID: PMC1805489
Trophoblast cell activation by trophinin ligation is implicated in human embryo implantation
Kazuhiro Sugihara, Daijiro Sugiyama, James Byrne, Don P. Wolf, Kevin P. Lowitz, Yoichi Kobayashi, Maryam Kabir-Salmani, Daita Nadano, Daisuke Aoki, Shiro Nozawa, Jun Nakayama, Tomas Mustelin, Erkki Ruoslahti, Naoto Yamaguchi, and Michiko N. Fukuda
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3799–3804. Published online 2007 February 26. doi: 10.1073/pnas.0611516104.
PMCID: PMC1805454
Cross-talk between Chk1 and Chk2 in double-mutant thymocytes
Kathrin Zaugg, Yu-Wen Su, Patrick T. Reilly, Yasmin Moolani, Carol C. Cheung, Razquallah Hakem, Atsushi Hirao, Quinghua Liu, Stephen J. Elledge, and Tak W. Mak
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3805–3810. Published online 2007 February 26. doi: 10.1073/pnas.0611584104.
PMCID: PMC1820665
Cell-cycle-dependent phosphorylation of the nuclear pore Nup107–160 subcomplex
Joseph S. Glavy, Andrew N. Krutchinsky, Ileana M. Cristea, Ian C. Berke, Thomas Boehmer, Günter Blobel, and Brian T. Chait
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3811–3816. Published online 2007 February 28. doi: 10.1073/pnas.0700058104.
PMCID: PMC1820666
Heterotrimeric G protein signaling in the Arabidopsis unfolded protein response
Shiyu Wang, Savitha Narendra, and Nina Fedoroff
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3817–3822. Published online 2007 February 28. doi: 10.1073/pnas.0611735104.
PMCID: PMC1820667
E-Syts, a family of membranous Ca2+-sensor proteins with multiple C2 domains
Sang-Won Min, Wen-Pin Chang, and Thomas C. Südhof
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3823–3828. Published online 2007 February 28. doi: 10.1073/pnas.0611725104.
PMCID: PMC1820668
c-Myb is required for progenitor cell homeostasis in colonic crypts
Jordane Malaterre, Marina Carpinelli, Matthias Ernst, Warren Alexander, Michael Cooke, Susan Sutton, Sebastian Dworkin, Joan K. Heath, Jon Frampton, Grant McArthur, Hans Clevers, Douglas Hilton, Theo Mantamadiotis, and Robert G. Ramsay
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3829–3834. Published online 2007 February 26. doi: 10.1073/pnas.0610055104.
PMCID: PMC1820669
Developmental Biology
On the mechanism of wing size determination in fly development
Lars Hufnagel, Aurelio A. Teleman, Hervé Rouault, Stephen M. Cohen, and Boris I. Shraiman
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3835–3840. Published online 2007 February 28. doi: 10.1073/pnas.0607134104.
PMCID: PMC1820670
C-type natriuretic peptide regulates blood–testis barrier dynamics in adult rat testes
Weiliang Xia, Dolores D. Mruk, and C. Yan Cheng
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3841–3846. Published online 2007 February 27. doi: 10.1073/pnas.0610100104.
PMCID: PMC1820671
Linking pattern formation to cell-type specification: Dichaete and Ind directly repress achaete gene expression in the Drosophila CNS
Guoyan Zhao, Grace Boekhoff-Falk, Beth A. Wilson, and James B. Skeath
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3847–3852. Published online 2007 February 26. doi: 10.1073/pnas.0611700104.
PMCID: PMC1820672
MafB is required for islet β cell maturation
Isabella Artner, Bruno Blanchi, Jeffrey C. Raum, Min Guo, Tomomi Kaneko, Sabine Cordes, Michael Sieweke, and Roland Stein
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3853–3858. Published online 2007 February 22. doi: 10.1073/pnas.0700013104.
PMCID: PMC1803762
Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells
Yu Liu, Masanori Asakura, Hironori Inoue, Teruya Nakamura, Motoaki Sano, Zhiyv Niu, Michelle Chen, Robert J. Schwartz, and Michael D. Schneider
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3859–3864. Published online 2007 February 28. doi: 10.1073/pnas.0609100104.
PMCID: PMC1820674
DMY gene induces male development in genetically female (XX) medaka fish
Masaru Matsuda, Ai Shinomiya, Masato Kinoshita, Aya Suzuki, Tohru Kobayashi, Bindhu Paul-Prasanth, En-lieng Lau, Satoshi Hamaguchi, Mitsuru Sakaizumi, and Yoshitaka Nagahama
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3865–3870. Published online 2007 February 28. doi: 10.1073/pnas.0611707104.
PMCID: PMC1820675
Interaction with the mammary microenvironment redirects spermatogenic cell fate in vivo
Corinne A. Boulanger, David L. Mack, Brian W. Booth, and Gilbert H. Smith
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3871–3876. Published online 2007 February 28. doi: 10.1073/pnas.0611637104.
PMCID: PMC1820676
Mechanisms controlling the acquisition of a cardiac phenotype by liver stem cells
Barbara J. Muller-Borer, Wayne E. Cascio, Gwyn L. Esch, Hyung-Suk Kim, William B. Coleman, Joe W. Grisham, Page A. W. Anderson, and Nadia N. Malouf
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3877–3882. Published online 2007 February 26. doi: 10.1073/pnas.0700416104.
PMCID: PMC1805456
Ecology
Delayed upwelling alters nearshore coastal ocean ecosystems in the northern California current
John A. Barth, Bruce A. Menge, Jane Lubchenco, Francis Chan, John M. Bane, Anthony R. Kirincich, Margaret A. McManus, Karina J. Nielsen, Stephen D. Pierce, and Libe Washburn
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3719–3724. Published online 2007 February 27. doi: 10.1073/pnas.0700462104.
PMCID: PMC1805484
From the Cover:
Increased genetic variation and evolutionary potential drive the success of an invasive grass
Sébastien Lavergne and Jane Molofsky
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3883–3888. Published online 2007 February 28. doi: 10.1073/pnas.0607324104.
PMCID: PMC1805698
Gene–environment interactions influence ecological consequences of transgenic animals
L. F. Sundström, M. Lõhmus, W. E. Tymchuk, and Robert H. Devlin
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3889–3894. Published online 2007 February 27. doi: 10.1073/pnas.0608767104.
PMCID: PMC1820679
Environmental Sciences
Chlorination of lignin by ubiquitous fungi has a likely role in global organochlorine production
Patricia Ortiz-Bermúdez, Kolby C. Hirth, Ewald Srebotnik, and Kenneth E. Hammel
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3895–3900. Published online 2007 February 26. doi: 10.1073/pnas.0610074104.
PMCID: PMC1820680
Evolution
From the Cover:
Prospects for fungus identification using CO1 DNA barcodes, with Penicillium as a test case
Keith A. Seifert, Robert A. Samson, Jeremy R. deWaard, Jos Houbraken, C. André Lévesque, Jean-Marc Moncalvo, Gerry Louis-Seize, and Paul D. N. Hebert
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3901–3906. Published online 2007 February 28. doi: 10.1073/pnas.0611691104.
PMCID: PMC1805696
Adaptive evolution in humans revealed by the negative correlation between the polymorphism and fixation phases of evolution
Jun Gojobori, Hua Tang, Joshua M. Akey, and Chung-I Wu
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3907–3912. Published online 2007 February 26. doi: 10.1073/pnas.0605565104.
PMCID: PMC1820682
Genetics
From the Cover:
Pollen tetrad-based visual assay for meiotic recombination in Arabidopsis
Kirk E. Francis, Sandy Y. Lam, Benjamin D. Harrison, Alexandra L. Bey, Luke E. Berchowitz, and Gregory P. Copenhaver
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3913–3918. Published online 2007 February 23. doi: 10.1073/pnas.0608936104.
PMCID: PMC1805420
Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development
Xianghua Zhou, Fei Tian, Johan Sandzén, Renhai Cao, Emilie Flaberg, Laszlo Szekely, Yihai Cao, Claes Ohlsson, Martin O. Bergo, Jan Borén, and Levent M. Akyürek
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3919–3924. Published online 2007 February 26. doi: 10.1073/pnas.0608360104.
PMCID: PMC1820684
Systematic genome instability screens in yeast and their potential relevance to cancer
Karen W. Y. Yuen, Cheryl D. Warren, Ou Chen, Teresa Kwok, Phil Hieter, and Forrest A. Spencer
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3925–3930. Published online 2007 February 28. doi: 10.1073/pnas.0610642104.
PMCID: PMC1820685
Ink4a/Arf tumor suppressor does not modulate the degenerative conditions or tumor spectrum of the telomerase-deficient mouse
Christine M. Khoo, Daniel R. Carrasco, Marcus W. Bosenberg, Ji-Hye Paik, and Ronald A. DePinho
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3931–3936. Published online 2007 February 27. doi: 10.1073/pnas.0700093104.
PMCID: PMC1820686
Skeletal overgrowth is mediated by deficiency in a specific isoform of fibroblast growth factor receptor 3
Veraragavan P. Eswarakumar and Joseph Schlessinger
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3937–3942. Published online 2007 February 23. doi: 10.1073/pnas.0700012104.
PMCID: PMC1820687
KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging
Karen Ocorr, Nick L. Reeves, Robert J. Wessells, Martin Fink, H.-S. Vincent Chen, Takeshi Akasaka, Soichiro Yasuda, Joseph M. Metzger, Wayne Giles, James W. Posakony, and Rolf Bodmer
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3943–3948. Published online 2007 February 28. doi: 10.1073/pnas.0609278104.
PMCID: PMC1820688
Targeted deletion of Wwox reveals a tumor suppressor function
Rami I. Aqeilan, Francesco Trapasso, Sadiq Hussain, Stefan Costinean, Dean Marshall, Yuri Pekarsky, John P. Hagan, Nicola Zanesi, Mohamed Kaou, Gary S. Stein, Jane B. Lian, and Carlo M. Croce
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3949–3954. Published online 2007 February 27. doi: 10.1073/pnas.0609783104.
PMCID: PMC1820689
Loss of a histone deacetylase dramatically alters the genomic distribution of Spo11p-catalyzed DNA breaks in Saccharomyces cerevisiae
Piotr A. Mieczkowski, Margaret Dominska, Michael J. Buck, Jason D. Lieb, and Thomas D. Petes
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3955–3960. Published online 2007 February 28. doi: 10.1073/pnas.0700412104.
PMCID: PMC1805699
Association of a common complement receptor 2 haplotype with increased risk of systemic lupus erythematosus
Hui Wu, Susan A. Boackle, Punchong Hanvivadhanakul, Daniela Ulgiati, Jennifer M. Grossman, Youngho Lee, Nan Shen, Lawrence J. Abraham, Timothy R. Mercer, Elly Park, Lee A. Hebert, Brad H. Rovin, Dan J. Birmingham, Deh-Ming Chang, Chung Jen Chen, Deborah McCurdy, Humeira M. Badsha, Bernard Y. H. Thong, Hiok H. Chng, Frank C. Arnett, Daniel J. Wallace, C. Yung Yu, Bevra H. Hahn, Rita M. Cantor, and Betty P. Tsao
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3961–3966. Published online 2007 February 22. doi: 10.1073/pnas.0609101104.
PMCID: PMC1820691
Immunology
CD8 tumor-infiltrating lymphocytes are predictive of survival in muscle-invasive urothelial carcinoma
Padmanee Sharma, Yu Shen, Sijin Wen, Sachiko Yamada, Achim A. Jungbluth, Sacha Gnjatic, Dean F. Bajorin, Victor E. Reuter, Harry Herr, Lloyd J. Old, and Eiichi Sato
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3967–3972. Published online 2007 February 27. doi: 10.1073/pnas.0611618104.
PMCID: PMC1820692
Innate response to self-antigen significantly exacerbates burn wound depth
Freeman Suber, Michael C. Carroll, and Francis D. Moore, Jr.
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3973–3977. Published online 2007 February 28. doi: 10.1073/pnas.0609026104.
PMCID: PMC1820693
Stable masking by H-2Dd cis ligand limits Ly49A relocalization to the site of NK cell/target cell contact
Jonathan Back, Anick Chalifour, Léonardo Scarpellino, and Werner Held
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3978–3983. Published online 2007 February 26. doi: 10.1073/pnas.0607418104.
PMCID: PMC1820694
Invariant NKT cells sustain specific B cell responses and memory
Grazia Galli, Paola Pittoni, Elena Tonti, Carmine Malzone, Yasushi Uematsu, Marco Tortoli, Domenico Maione, Gianfranco Volpini, Oretta Finco, Sandra Nuti, Simona Tavarini, Paolo Dellabona, Rino Rappuoli, Giulia Casorati, and Sergio Abrignani
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3984–3989. Published online 2007 February 27. doi: 10.1073/pnas.0700191104.
PMCID: PMC1805488
Immunotherapeutic activity of a conjugate of a Toll-like receptor 7 ligand
Christina C. N. Wu, Tomoko Hayashi, Kenji Takabayashi, Mojgan Sabet, Donald F. Smee, Donald D. Guiney, Howard B. Cottam, and Dennis A. Carson
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3990–3995. Published online 2007 February 21. doi: 10.1073/pnas.0611624104.
PMCID: PMC1820696
From the Cover:
Endogenous IL-12 triggers an antiangiogenic program in melanoma cells
Irma Airoldi, Emma Di Carlo, Claudia Cocco, Giuseppe Taverniti, Tommaso D'Antuono, Emanuela Ognio, Morihiro Watanabe, Domenico Ribatti, and Vito Pistoia
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3996–4001. Published online 2007 February 23. doi: 10.1073/pnas.0609028104.
PMCID: PMC1820697
Restriction of endogenous T cell antigen receptor β rearrangements to Vβ14 through selective recombination signal sequence modifications
Cherry Wu, Sheila Ranganath, Megan Gleason, Barbara B. Woodman, Tiffany M. Borjeson, Frederick W. Alt, and Craig H. Bassing
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4002–4007. Published online 2007 February 27. doi: 10.1073/pnas.0700081104.
PMCID: PMC1820698
Medical Sciences
Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer
Matthew D. Johnston, Carina M. Edwards, Walter F. Bodmer, Philip K. Maini, and S. Jonathan Chapman
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4008–4013. Published online 2007 February 28. doi: 10.1073/pnas.0611179104.
PMCID: PMC1820699
Predicting response to breast cancer neoadjuvant chemotherapy using diffuse optical spectroscopy
Albert Cerussi, David Hsiang, Natasha Shah, Rita Mehta, Amanda Durkin, John Butler, and Bruce J. Tromberg
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4014–4019. Published online 2007 February 28. doi: 10.1073/pnas.0611058104.
PMCID: PMC1805697
WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo
Aaron M. Ring, Sam X. Cheng, Qiang Leng, Kristopher T. Kahle, Jesse Rinehart, Maria D. Lalioti, Heather M. Volkman, Frederick H. Wilson, Steven C. Hebert, and Richard P. Lifton
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4020–4024. Published online 2007 February 26. doi: 10.1073/pnas.0611727104.
PMCID: PMC1805455
An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis
Aaron M. Ring, Qiang Leng, Jesse Rinehart, Frederick H. Wilson, Kristopher T. Kahle, Steven C. Hebert, and Richard P. Lifton
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4025–4029. Published online 2007 February 22. doi: 10.1073/pnas.0611728104.
PMCID: PMC1803763
Fusion of proinsulin-producing bone marrow-derived cells with hepatocytes in diabetes
Mineko Fujimiya, Hideto Kojima, Masumi Ichinose, Ryohachi Arai, Hiroshi Kimura, Atsunori Kashiwagi, and Lawrence Chan
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4030–4035. Published online 2007 February 27. doi: 10.1073/pnas.0700220104.
PMCID: PMC1820703
A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancer
James M. Amos-Landgraf, Lawrence N. Kwong, Christina M. Kendziorski, Mark Reichelderfer, Jose Torrealba, Jamey Weichert, Jill D. Haag, Kai-Shun Chen, Jordy L. Waller, Michael N. Gould, and William F. Dove
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4036–4041. Published online 2007 February 27. doi: 10.1073/pnas.0611690104.
PMCID: PMC1805486
Spatial navigation deficit in amnestic mild cognitive impairment
Jakub Hort, Jan Laczó, Martin Vyhnálek, Martin Bojar, Jan Bureš, and Kamil Vlček
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4042–4047. Published online 2007 February 28. doi: 10.1073/pnas.0611314104.
PMCID: PMC1820705
Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma
Craig D. Peacock, Qiuju Wang, Gregory S. Gesell, Ian M. Corcoran-Schwartz, Evan Jones, Jynho Kim, Wendy L. Devereux, Jonathan T. Rhodes, Carol A. Huff, Philip A. Beachy, D. Neil Watkins, and William Matsui
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4048–4053. Published online 2007 February 27. doi: 10.1073/pnas.0611682104.
PMCID: PMC1805487
The nuclear function of p53 is required for PUMA-mediated apoptosis induced by DNA damage
Peng Wang, Jian Yu, and Lin Zhang
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4054–4059. Published online 2007 February 28. doi: 10.1073/pnas.0700020104.
PMCID: PMC1820707
Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T
Xiaodong Zhang, Ailan Guo, Jianshi Yu, Anthony Possemato, Yueting Chen, Weiping Zheng, Roberto D. Polakiewicz, Kenneth W. Kinzler, Bert Vogelstein, Victor E. Velculescu, and Zhenghe John Wang
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4060–4064. Published online 2007 February 21. doi: 10.1073/pnas.0611665104.
PMCID: PMC1802729
Steroid receptor coactivator 3 is a coactivator for myocardin, the regulator of smooth muscle transcription and differentiation
Hui Joyce Li, Zaffar Haque, Qing Lu, Li Li, Richard Karas, and Michael Mendelsohn
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4065–4070. Published online 2007 February 28. doi: 10.1073/pnas.0611639104.
PMCID: PMC1820709
A phase I clinical trial with monoclonal antibody ch806 targeting transitional state and mutant epidermal growth factor receptors
Andrew M. Scott, Fook-Thean Lee, Niall Tebbutt, Rebecca Herbertson, Sanjeev S. Gill, Zhanqi Liu, Effie Skrinos, Carmel Murone, Timothy H. Saunder, Bridget Chappell, Anthony T. Papenfuss, Aurora M. T. Poon, Wendie Hopkins, Fiona E. Smyth, Duncan MacGregor, Lawrence M. Cher, Achim A. Jungbluth, Gerd Ritter, Martin W. Brechbiel, Roger Murphy, Antony W. Burgess, Eric W. Hoffman, Terrance G. Johns, and Lloyd J. Old
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4071–4076. Published online 2007 February 28. doi: 10.1073/pnas.0611693104.
PMCID: PMC1805701
α-Lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway
Wei-Jian Zhang, Hao Wei, Tory Hagen, and Balz Frei
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4077–4082. Published online 2007 February 27. doi: 10.1073/pnas.0700305104.
PMCID: PMC1805485
Adenosine regulation of alveolar fluid clearance
Phillip Factor, Göskhan M. Mutlu, Lan Chen, Jameel Mohameed, Alexander T. Akhmedov, Fan Jing Meng, Tamas Jilling, Erin Rachel Lewis, Meshell D. Johnson, Anna Xu, Daniel Kass, Janice M. Martino, Amy Bellmeyer, John S. Albazi, Charles Emala, H. T. Lee, Leland G. Dobbs, and Sadis Matalon
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4083–4088. Published online 2007 February 28. doi: 10.1073/pnas.0601117104.
PMCID: PMC1820712
Transgenic cyclin E triggers dysplasia and multiple pulmonary adenocarcinomas
Yan Ma, Steven Fiering, Candice Black, Xi Liu, Ziqiang Yuan, Vincent A. Memoli, David J. Robbins, Heather A. Bentley, Gregory J. Tsongalis, Eugene Demidenko, Sarah J. Freemantle, and Ethan Dmitrovsky
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4089–4094. Published online 2007 February 27. doi: 10.1073/pnas.0606537104.
PMCID: PMC1820713
Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1
Dan Peer, Pengcheng Zhu, Christopher V. Carman, Judy Lieberman, and Motomu Shimaoka
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4095–4100. Published online 2007 February 28. doi: 10.1073/pnas.0608491104.
PMCID: PMC1820714
Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations
Marianthi Georgitsi, Anniina Raitila, Auli Karhu, Karoliina Tuppurainen, Markus J. Mäkinen, Outi Vierimaa, Ralf Paschke, Wolfgang Saeger, Rob B. van der Luijt, Timo Sane, Mercedes Robledo, Ernesto De Menis, Robert J. Weil, Anna Wasik, Grzegorz Zielinski, Olga Lucewicz, Jan Lubinski, Virpi Launonen, Pia Vahteristo, and Lauri A. Aaltonen
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4101–4105. Published online 2007 February 28. doi: 10.1073/pnas.0700004104.
PMCID: PMC1820715
Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase
Mark G. Manfredi, Jeffrey A. Ecsedy, Kristan A. Meetze, Suresh K. Balani, Olga Burenkova, Wei Chen, Katherine M. Galvin, Kara M. Hoar, Jessica J. Huck, Patrick J. LeRoy, Emily T. Ray, Todd B. Sells, Bradley Stringer, Stephen G. Stroud, Tricia J. Vos, Gabriel S. Weatherhead, Deborah R. Wysong, Mengkun Zhang, Joseph B. Bolen, and Christopher F. Claiborne
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4106–4111. Published online 2007 February 23. doi: 10.1073/pnas.0608798104.
PMCID: PMC1820716
Microbiology
DgrA is a member of a new family of cyclic diguanosine monophosphate receptors and controls flagellar motor function in Caulobacter crescentus
Matthias Christen, Beat Christen, Martin G. Allan, Marc Folcher, Paul Jenö, Stephan Grzesiek, and Urs Jenal
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4112–4117. Published online 2007 February 27. doi: 10.1073/pnas.0607738104.
PMCID: PMC1805490
Distinct roles of haptoglobin-related protein and apolipoprotein L-I in trypanolysis by human serum
Benoit Vanhollebeke, Marianne J. Nielsen, Yoshihisa Watanabe, Philippe Truc, Luc Vanhamme, Kazunori Nakajima, Soren K. Moestrup, and Etienne Pays
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4118–4123. Published online 2007 February 26. doi: 10.1073/pnas.0609902104.
PMCID: PMC1820718
Escherichia coli enzyme IIANtr regulates the K+ transporter TrkA
Chang-Ro Lee, Seung-Hyon Cho, Mi-Jeong Yoon, Alan Peterkofsky, and Yeong-Jae Seok
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4124–4129. Published online 2007 February 8. doi: 10.1073/pnas.0609897104.
PMCID: PMC1794712
HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1
Bärbel Schröfelbauer, Yoshiyuki Hakata, and Nathaniel R. Landau
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4130–4135. Published online 2007 February 28. doi: 10.1073/pnas.0610167104.
PMCID: PMC1820720
Attenuated virulence of a Francisella mutant lacking the lipid A 4′-phosphatase
Xiaoyuan Wang, Anthony A. Ribeiro, Ziqiang Guan, Soman N. Abraham, and Christian R. H. Raetz
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4136–4141. Published online 2007 February 26. doi: 10.1073/pnas.0611606104.
PMCID: PMC1820721
Separation of receptor-binding and profusogenic domains of glycoprotein D of herpes simplex virus 1 into distinct interacting proteins
Guoying Zhou and Bernard Roizman
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4142–4146. Published online 2007 February 27. doi: 10.1073/pnas.0611565104.
PMCID: PMC1820722
Neuroscience
Inhibition of Cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine
Jane R. Taylor, Wendy J. Lynch, Hayde Sanchez, Peter Olausson, Eric J. Nestler, and James A. Bibb
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4147–4152. Published online 2007 February 23. doi: 10.1073/pnas.0610288104.
PMCID: PMC1820723
Cortical area size dictates performance at modality-specific behaviors
Axel Leingärtner, Sandrine Thuret, Todd T. Kroll, Shen-Ju Chou, J. Leigh Leasure, Fred H. Gage, and Dennis D. M. O'Leary
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4153–4158. Published online 2007 February 27. doi: 10.1073/pnas.0611723104.
PMCID: PMC1820724
Regulation of Alzheimer's disease amyloid-β formation by casein kinase I
Marc Flajolet, Gen He, Myriam Heiman, Angie Lin, Angus C. Nairn, and Paul Greengard
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4159–4164. Published online 2007 February 27. doi: 10.1073/pnas.0611236104.
PMCID: PMC1820725
Stimulus-specific competitive selection in macaque extrastriate visual area V4
Mazyar Fallah, Gene R. Stoner, and John H. Reynolds
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4165–4169. Published online 2007 February 28. doi: 10.1073/pnas.0611722104.
PMCID: PMC1820726
Ischemic insults promote epigenetic reprogramming of μ opioid receptor expression in hippocampal neurons
Luigi Formisano, Kyung-Min Noh, Takahiro Miyawaki, Toshihiro Mashiko, Michael V. L. Bennett, and R. Suzanne Zukin
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4170–4175. Published online 2007 February 28. doi: 10.1073/pnas.0611704104.
PMCID: PMC1820727
PSD-95 is required for activity-driven synapse stabilization
Ingrid Ehrlich, Matthew Klein, Simon Rumpel, and Roberto Malinow
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4176–4181. Published online 2007 February 27. doi: 10.1073/pnas.0609307104.
PMCID: PMC1820728
Ablation of D1 dopamine receptor-expressing cells generates mice with seizures, dystonia, hyperactivity, and impaired oral behavior
Ilse Gantois, Ke Fang, Luning Jiang, Daniela Babovic, Andrew J. Lawrence, Vincenzo Ferreri, Yaroslav Teper, Bianca Jupp, Jenna Ziebell, Cristina M. Morganti-Kossmann, Terence J. O'Brien, Rachel Nally, Günter Schütz, John Waddington, Gary F. Egan, and John Drago
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4182–4187. Published online 2007 February 28. doi: 10.1073/pnas.0611625104.
PMCID: PMC1820729
A coherent neurobiological framework for functional neuroimaging provided by a model integrating compartmentalized energy metabolism
Agnès Aubert, Luc Pellerin, Pierre J. Magistretti, and Robert Costalat
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4188–4193. Published online 2007 February 28. doi: 10.1073/pnas.0605864104.
PMCID: PMC1820730
Neuronal growth and survival mediated by eIF5A, a polyamine-modified translation initiation factor
Yunfei Huang, Daniel S. Higginson, Lynda Hester, Myung Hee Park, and Solomon H. Snyder
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4194–4199. Published online 2007 February 28. doi: 10.1073/pnas.0611609104.
PMCID: PMC1820731
Physiology
The proton pumping pathway of bovine heart cytochrome c oxidase
Kunitoshi Shimokata, Yukie Katayama, Haruka Murayama, Makoto Suematsu, Tomitake Tsukihara, Kazumasa Muramoto, Hiroshi Aoyama, Shinya Yoshikawa, and Hideo Shimada
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4200–4205. Published online 2007 February 28. doi: 10.1073/pnas.0611627104.
PMCID: PMC1820732
Urocortin 3 regulates glucose-stimulated insulin secretion and energy homeostasis
Chien Li, Peilin Chen, Joan Vaughan, Kuo-Fen Lee, and Wylie Vale
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4206–4211. Published online 2007 February 27. doi: 10.1073/pnas.0611641104.
PMCID: PMC1820733
Two forms of single-vesicle astrocyte exocytosis imaged with total internal reflection fluorescence microscopy
David N. Bowser and Baljit S. Khakh
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4212–4217. Published online 2007 February 26. doi: 10.1073/pnas.0607625104.
PMCID: PMC1820734
Plant Biology
From the Cover:
Folate biofortification of tomato fruit
Rocío I. Díaz de la Garza, Jesse F. Gregory, III, and Andrew D. Hanson
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4218–4222. Published online 2007 March 5. doi: 10.1073/pnas.0700409104.
PMCID: PMC1810332
Population Biology
Using DNA to track the origin of the largest ivory seizure since the 1989 trade ban
Samuel K. Wasser, Celia Mailand, Rebecca Booth, Benezeth Mutayoba, Emily Kisamo, Bill Clark, and Matthew Stephens
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4228–4233. Published online 2007 February 26. doi: 10.1073/pnas.0609714104.
PMCID: PMC1805457
Psychology
Functional and morphometric brain dissociation between dyslexia and reading ability
Fumiko Hoeft, Ann Meyler, Arvel Hernandez, Connie Juel, Heather Taylor-Hill, Jennifer L. Martindale, Glenn McMillon, Galena Kolchugina, Jessica M. Black, Afrooz Faizi, Gayle K. Deutsch, Wai Ting Siok, Allan L. Reiss, Susan Whitfield-Gabrieli, and John D. E. Gabrieli
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4234–4239. Published online 2007 February 23. doi: 10.1073/pnas.0609399104.
PMCID: PMC1820738
Cell Biology
Correction for Amthor et al., Lack of myostatin results in excessive muscle growth but impaired force generation
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4240. Published online 2007 February 23. doi: 10.1073/pnas.0701154104.
PMCID: PMC1820739
Corrects: Helge Amthor, et al. Lack of myostatin results in excessive muscle growth but impaired force generation. Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1835–1840.
Medical Sciences
Correction for Palomero et al., NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth
Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4240. Published online 2007 February 23. doi: 10.1073/pnas.0700840104.
PMCID: PMC1820740
Corrects: Teresa Palomero, et al. NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth. Proc Natl Acad Sci U S A. 2006 November 28; 103(48): 18261–18266.
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