| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2007 February 27; 104(9): 3017–3018. doi: 10.1073/iti0907104.PMCID: PMC1805565 Commentaries Illuminating the molecular basis for some antipsychotic drug-induced metabolic burden Herbert Y. Meltzer PMCID: PMC1805573 Small is big: The microfossil perspective on human–plant interaction Daniel H. Sandweiss PMCID: PMC1805511 Profile Profile of Joseph R. Ecker Bijal P. Trivedi PMCID: PMC1805523 Physical Sciences Chemistry Effect of carbonates/phosphates as nucleophilic catalysts in dimethylformamide for efficient cyanosilylation of aldehydes and ketones G. K. Surya Prakash, Habiba Vaghoo, Chiradeep Panja, Vijayalakshmi Surampudi, Roman Kultyshev, Thomas Mathew, and George A. Olah PMCID: PMC1805593 Engineering From the Cover:
Interfacial plasticity governs strain rate sensitivity and ductility in nanostructured metals Ting Zhu, Ju Li, Amit Samanta, Hyoung Gyu Kim, and Subra Suresh PMCID: PMC1805608 Environmental Sciences An estimate of anthropogenic CO2 inventory from decadal changes in oceanic carbon content Toste Tanhua, Arne Körtzinger, Karsten Friis, Darryn W. Waugh, and Douglas W. R. Wallace PMCID: PMC1802019 Biological Sciences Anthropology 4,300-Year-old chimpanzee sites and the origins of percussive stone technology Julio Mercader, Huw Barton, Jason Gillespie, Jack Harris, Steven Kuhn, Robert Tyler, and Christophe Boesch PMCID: PMC1805589 From the Cover:
Starch grain evidence for the preceramic dispersals of maize and root crops into tropical dry and humid forests of Panama Ruth Dickau, Anthony J. Ranere, and Richard G. Cooke PMCID: PMC1805539 Applied Biological Sciences Biomimetic tissue-engineered anterior cruciate ligament replacement James A. Cooper, Jr., Janmeet S. Sahota, W. Jay Gorum, II, Janell Carter, Stephen B. Doty, and Cato T. Laurencin PMCID: PMC1805619 Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases Erica A. Moehle, Jeremy M. Rock, Ya-Li Lee, Yann Jouvenot, Russell C. DeKelver, Philip D. Gregory, Fyodor D. Urnov, and Michael C. Holmes PMCID: PMC1802009 Biochemistry Quantifying DNA–protein binding specificities by using oligonucleotide mass tags and mass spectroscopy Lingang Zhang, Simon Kasif, and and Charles R. Cantor PMCID: PMC1805538 In vitro analysis of DNA–protein interactions by proximity ligation Sigrun M. Gustafsdottir, Joerg Schlingemann, Alvaro Rada-Iglesias, Edith Schallmeiner, Masood Kamali-Moghaddam, Claes Wadelius, and Ulf Landegren PMCID: PMC1805562 Structure of the non-redox-active tungsten/[4Fe:4S] enzyme acetylene hydratase Grazyna B. Seiffert, G. Matthias Ullmann, Albrecht Messerschmidt, Bernhard Schink, Peter M. H. Kroneck, and Oliver Einsle PMCID: PMC1805521 Requirements for DNA hairpin formation by RAG1/2 Gabrielle J. Grundy, Joanne E. Hesse, and Martin Gellert PMCID: PMC1805602 Fusicoccins are biosynthesized by an unusual chimera diterpene synthase in fungi Tomonobu Toyomasu, Mai Tsukahara, Akane Kaneko, Rie Niida, Wataru Mitsuhashi, Tohru Dairi, Nobuo Kato, and Takeshi Sassa PMCID: PMC1805559 Evidence for a dual binding mode of dockerin modules to cohesins Ana Luísa Carvalho, Fernando M. V. Dias, Tibor Nagy, José A. M. Prates, Mark R. Proctor, Nicola Smith, Edward A. Bayer, Gideon J. Davies, Luís M. A. Ferreira, Maria J. Romão, Carlos M. G. A. Fontes, and Harry J. Gilbert PMCID: PMC1805526 From the Cover:
Structure of the Parkin in-between-ring domain provides insights for E3-ligase dysfunction in autosomal recessive Parkinson's disease Steven A. Beasley, Ventzislava A. Hristova, and Gary S. Shaw PMCID: PMC1805599 Trigger Factor can antagonize both SecB and DnaK/DnaJ chaperone functions in Escherichia coli Ronald S. Ullers, Debbie Ang, Françoise Schwager, Costa Georgopoulos, and Pierre Genevaux PMCID: PMC1805596 Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization Begoña García-Álvarez, Guillermo de Cárcer, Sonia Ibañez, Elisabeth Bragado-Nilsson, and Guillermo Montoya PMCID: PMC1805623 Structural basis and evolutionary origin of actin filament capping by twinfilin Ville O. Paavilainen, Maarit Hellman, Emmanuèle Helfer, Miia Bovellan, Arto Annila, Marie-France Carlier, Perttu Permi, and Pekka Lappalainen PMCID: PMC1805582 Concerted ATP-induced allosteric transitions in GroEL facilitate release of protein substrate domains in an all-or-none manner Yakov Kipnis, Niv Papo, Gilad Haran, and Amnon Horovitz PMCID: PMC1805612 Each rhodopsin molecule binds its own arrestin Susan M. Hanson, Eugenia V. Gurevich, Sergey A. Vishnivetskiy, Mohamed R. Ahmed, Xiufeng Song, and Vsevolod V. Gurevich PMCID: PMC1805568 RNA-binding proteins that inhibit RNA virus infection Jian Zhu, Kodetham Gopinath, Ayaluru Murali, Guanghui Yi, S. Diane Hayward, Heng Zhu, and Cheng Kao PMCID: PMC1805585 Regulation of a glutamyl-tRNA synthetase by the heme status Gloria Levicán, Assaf Katz, Merly de Armas, Harold Núñez, and Omar Orellana PMCID: PMC1805545 Pyrrolysine is not hardwired for cotranslational insertion at UAG codons Alexandre Ambrogelly, Sarath Gundllapalli, Stephanie Herring, Carla Polycarpo, Carina Frauer, and Dieter Söll PMCID: PMC1805618 Biophysics Determining the stoichiometry of protein heterocomplexes in living cells with fluorescence fluctuation spectroscopy Yan Chen and Joachim D. Müller PMCID: PMC1805531 Intramolecular domain–domain association/dissociation and phosphoryl transfer in the mannitol transporter of Escherichia coli are not coupled Jeong-Yong Suh, Junji Iwahara, and G. Marius Clore PMCID: PMC1805604 Establishing the entatic state in folding metallated Pseudomonas aeruginosa azurin Chenghang Zong, Corey J. Wilson, Tongye Shen, Pernilla Wittung-Stafshede, Steven L. Mayo, and Peter G. Wolynes PMCID: PMC1805512 Large-scale fluid/fluid phase separation of proteins and lipids in giant plasma membrane vesicles Tobias Baumgart, Adam T. Hammond, Prabuddha Sengupta, Samuel T. Hess, David A. Holowka, Barbara A. Baird, and Watt W. Webb PMCID: PMC1805587 Extending the absorbing boundary method to fit dwell-time distributions of molecular motors with complex kinetic pathways Jung-Chi Liao, James A. Spudich, David Parker, and Scott L. Delp PMCID: PMC1805548 Near-native structure refinement using in vacuo energy minimization Christopher M. Summa and Michael Levitt PMCID: PMC1802011 Growth of novel protein structural data Michael Levitt PMCID: PMC1802002 Cell Biology Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2 Daniel W. Young, Mohammad Q. Hassan, Xiao-Qing Yang, Mario Galindo, Amjad Javed, Sayyed K. Zaidi, Paul Furcinitti, David Lapointe, Martin Montecino, Jane B. Lian, Janet L. Stein, Andre J. van Wijnen, and Gary S. Stein PMCID: PMC1805558 Structural characterization of the fission yeast U5.U2/U6 spliceosome complex Melanie D. Ohi, Liping Ren, Joseph S. Wall, Kathleen L. Gould, and Thomas Walz PMCID: PMC1805518 Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1γ Fuminobu Kuroda, Joel Moss, and Martha Vaughan PMCID: PMC1805514 Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomas Jose M. Polo, Przemyslaw Juszczynski, Stefano Monti, Leandro Cerchietti, Kenny Ye, John M. Greally, Margaret Shipp, and Ari Melnick PMCID: PMC1805543 Loss of α-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulated synaptic function Koji Ikegami, Robb L. Heier, Midori Taruishi, Hiroshi Takagi, Masahiro Mukai, Shuichi Shimma, Shu Taira, Ken Hatanaka, Nobuhiro Morone, Ikuko Yao, Patrick K. Campbell, Shigeki Yuasa, Carsten Janke, Grant R. MacGregor, and Mitsutoshi Setou PMCID: PMC1802010 Developmental Biology Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting I. B. Lobov, R. A. Renard, N. Papadopoulos, N. W. Gale, G. Thurston, G. D. Yancopoulos, and S. J. Wiegand PMCID: PMC1805530 The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching Steven Suchting, Catarina Freitas, Ferdinand le Noble, Rui Benedito, Christiane Bréant, Antonio Duarte, and Anne Eichmann PMCID: PMC1805603 Reciprocal asymmetry of SYS-1/β-catenin and POP-1/TCF controls asymmetric divisions in Caenorhabditis elegans Bryan T. Phillips, Ambrose R. Kidd, III, Ryan King, Jeff Hardin, and Judith Kimble PMCID: PMC1796998 Promoter targeting sequence mediates enhancer interference in the Drosophila embryo Qing Lin, Qi Chen, Lan Lin, Sheryl Smith, and Jumin Zhou PMCID: PMC1805586 Vascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesis Melissa G. Dominguez, Virginia C. Hughes, Li Pan, Mary Simmons, Christopher Daly, Keith Anderson, Irene Noguera-Troise, Andrew J. Murphy, David M. Valenzuela, Samuel Davis, Gavin Thurston, George D. Yancopoulos, and Nicholas W. Gale PMCID: PMC1802730 An ancient chordin-like gene in organizer formation of Hydra Fabian Rentzsch, Corina Guder, Dirk Vocke, Bert Hobmayer, and Thomas W. Holstein PMCID: PMC1805574 p63 induces key target genes required for epidermal morphogenesis Maranke I. Koster, Daisy Dai, Barbara Marinari, Yuji Sano, Antonio Costanzo, Michael Karin, and Dennis R. Roop PMCID: PMC1805532 The Nf2 tumor suppressor regulates cell–cell adhesion during tissue fusion Margaret E. McLaughlin, Genevieve M. Kruger, Kelly L. Slocum, Denise Crowley, Norman A. Michaud, Jennifer Huang, Margaret Magendantz, and Tyler Jacks PMCID: PMC1801999 Ecology Complex larval connectivity patterns among marine invertebrate populations Bonnie J. Becker, Lisa A. Levin, F. Joel Fodrie, and Pat A. McMillan PMCID: PMC1802003 From the Cover:
Compensatory dynamics are rare in natural ecological communities J. E. Houlahan, D. J. Currie, K. Cottenie, G. S. Cumming, S. K. M. Ernest, C. S. Findlay, S. D. Fuhlendorf, U. Gaedke, P. Legendre, J. J. Magnuson, B. H. McArdle, E. H. Muldavin, D. Noble, R. Russell, R. D. Stevens, T. J. Willis, I. P. Woiwod, and S. M. Wondzell PMCID: PMC1805590 Differential contribution of frugivores to complex seed dispersal patterns P. Jordano, C. García, J. A. Godoy, and J. L. García-Castaño PMCID: PMC1805555 Evolution Systems-level analysis and evolution of the phototransduction network in Drosophila Christian R. Landry, Cristian I. Castillo-Davis, Atsushi Ogura, Jun S. Liu, and Daniel L. Hartl PMCID: PMC1805570 Genetic evidence for a second domestication of barley (Hordeum vulgare) east of the Fertile Crescent Peter L. Morrell and Michael T. Clegg PMCID: PMC1805597 Multigene phylogeny reveals eusociality evolved twice in vespid wasps Heather M. Hines, James H. Hunt, Timothy K. O'Connor, Joseph J. Gillespie, and Sydney A. Cameron PMCID: PMC1805554 Human polymorphism at microRNAs and microRNA target sites Matthew A. Saunders, Han Liang, and Wen-Hsiung Li PMCID: PMC1805605 An Andean origin of Phytophthora infestans inferred from mitochondrial and nuclear gene genealogies Luis Gómez-Alpizar, Ignazio Carbone, and Jean Beagle Ristaino PMCID: PMC1805513 Genetics An optimized transgenesis system for Drosophila using germ-line-specific ![[var phi]](corehtml/pmc/pmcents/x03C6.gif) C31 integrases Johannes Bischof, Robert K. Maeda, Monika Hediger, François Karch, and Konrad Basler PMCID: PMC1805588 Bioinformatic prediction and experimental validation of a microRNA-directed tandem trans-acting siRNA cascade in Arabidopsis Ho-Ming Chen, Yi-Hang Li, and Shu-Hsing Wu PMCID: PMC1805617 Serial analysis of chromatin occupancy identifies β-catenin target genes in colorectal carcinoma cells Gregory S. Yochum, Shannon McWeeney, Veena Rajaraman, Ryan Cleland, Sandra Peters, and Richard H. Goodman PMCID: PMC1805576 Potential targets of FOXL2, a transcription factor involved in craniofacial and follicular development, identified by transcriptomics Frank Batista, Daniel Vaiman, Jean Dausset, Marc Fellous, and Reiner A. Veitia PMCID: PMC1805535 A common variant in combination with a nonsense mutation in a member of the thioredoxin family causes primary ciliary dyskinesia Bénédicte Duriez, Philippe Duquesnoy, Estelle Escudier, Anne-Marie Bridoux, Denise Escalier, Isabelle Rayet, Elisabeth Marcos, Anne-Marie Vojtek, Jean-François Bercher, and Serge Amselem PMCID: PMC1805560 Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation Brooke H. Miller, Erin L. McDearmon, Satchidananda Panda, Kevin R. Hayes, Jie Zhang, Jessica L. Andrews, Marina P. Antoch, John R. Walker, Karyn A. Esser, John B. Hogenesch, and Joseph S. Takahashi PMCID: PMC1802006 Arabidopsis intragenomic conserved noncoding sequence Brian C. Thomas, Lakshmi Rapaka, Eric Lyons, Brent Pedersen, and Michael Freeling PMCID: PMC1805546 Immunology A haplotype of the human CXCR1 gene protective against rapid disease progression in HIV-1+ patients A. Vasilescu, Y. Terashima, M. Enomoto, S. Heath, V. Poonpiriya, H. Gatanaga, H. Do, G. Diop, T. Hirtzig, P. Auewarakul, D. Lauhakirti, T. Sura, P. Charneau, S. Marullo, A. Therwath, S. Oka, S. Kanegasaki, M. Lathrop, K. Matsushima, J.-F. Zagury, and F. Matsuda PMCID: PMC1805621 Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer Junzo Hamanishi, Masaki Mandai, Masashi Iwasaki, Taku Okazaki, Yoshimasa Tanaka, Ken Yamaguchi, Toshihiro Higuchi, Haruhiko Yagi, Kenji Takakura, Nagahiro Minato, Tasuku Honjo, and Shingo Fujii PMCID: PMC1805580 Host shutoff during productive Epstein–Barr virus infection is mediated by BGLF5 and may contribute to immune evasion Martin Rowe, Britt Glaunsinger, Daphne van Leeuwen, Jianmin Zuo, David Sweetman, Don Ganem, Jaap Middeldorp, Emmanuel J. H. J. Wiertz, and Maaike E. Ressing PMCID: PMC1805610 NF-κB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1 Sinead M. Miggin, Eva Pålsson-McDermott, Aisling Dunne, Caroline Jefferies, Emmanuel Pinteaux, Kathy Banahan, Caroline Murphy, Paul Moynagh, Masahiro Yamamoto, Shizuo Akira, Nancy Rothwell, Douglas Golenbock, Katherine A. Fitzgerald, and Luke A. J. O'Neill PMCID: PMC1805564 TGFβ promotes conversion of CD16+ peripheral blood NK cells into CD16− NK cells with similarities to decidual NK cells Derin B. Keskin, David S. J. Allan, Basya Rybalov, Milena M. Andzelm, Joel N. H. Stern, Hernan D. Kopcow, Louise A. Koopman, and Jack L. Strominger PMCID: PMC1805591 Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46 Thierry Walzer, Mathieu Bléry, Julie Chaix, Nicolas Fuseri, Lionel Chasson, Scott H. Robbins, Sébastien Jaeger, Pascale André, Laurent Gauthier, Laurent Daniel, Karine Chemin, Yannis Morel, Marc Dalod, Jean Imbert, Michel Pierres, Alessandro Moretta, François Romagné, and Eric Vivier PMCID: PMC1805551 Suppression of HIV-specific T cell activity by lymph node CD25+ regulatory T cells from HIV-infected individuals Audrey Kinter, Jonathan McNally, Lindsey Riggin, Robert Jackson, Gregg Roby, and Anthony S. Fauci PMCID: PMC1805624 HIV-1 gp120 inhibits TLR9-mediated activation and IFN-α secretion in plasmacytoid dendritic cells Elena Martinelli, Claudia Cicala, Donald Van Ryk, Diana J. Goode, Katilyn Macleod, James Arthos, and Anthony S. Fauci PMCID: PMC1805537 Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression Hideyuki Yanai, Hui-min Chen, Takayuki Inuzuka, Seiji Kondo, Tak W. Mak, Akinori Takaoka, Kenya Honda, and Tadatsugu Taniguchi PMCID: PMC1805533 Medical Sciences Methionine transmethylation and transsulfuration in the piglet gastrointestinal tract Maaike A. Riedijk, Barbara Stoll, Shaji Chacko, Henk Schierbeek, Agneta L. Sunehag, Johannes B. van Goudoever, and Douglas G. Burrin PMCID: PMC1805557 Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas Nathan D. Price, Jonathan Trent, Adel K. El-Naggar, David Cogdell, Ellen Taylor, Kelly K. Hunt, Raphael E. Pollock, Leroy Hood, Ilya Shmulevich, and Wei Zhang PMCID: PMC1805517 Adrenomedullin gene expression differences in mice do not affect blood pressure but modulate hypertension-induced pathology in males Kathleen Caron, John Hagaman, Toshio Nishikimi, Hyung-Suk Kim, and Oliver Smithies PMCID: PMC1802008 An intronic element contributes to splicing repression in spinal muscular atrophy Tsuyoshi Kashima, Nishta Rao, and James L. Manley PMCID: PMC1805620 MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-β-induced collagen expression via inhibition of E-box repressors Mitsuo Kato, Jane Zhang, Mei Wang, Linda Lanting, Hang Yuan, John J. Rossi, and Rama Natarajan PMCID: PMC1805579 HIV-tat induces formation of an LRP–PSD-95– NMDAR–nNOS complex that promotes apoptosis in neurons and astrocytes Eliseo A. Eugenin, Jessie E. King, Avindra Nath, Tina M. Calderon, R. Suzanne Zukin, Michael V. L. Bennett, and Joan W. Berman PMCID: PMC1805607 Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy Michael H. Radke, Jun Peng, Yiming Wu, Mark McNabb, O. Lynne Nelson, Henk Granzier, and Michael Gotthardt PMCID: PMC1805563 Circadian variation of blood pressure and the vascular response to asynchronous stress Anne M. Curtis, Yan Cheng, Shiv Kapoor, Dermot Reilly, Tom S. Price, and Garret A. FitzGerald PMCID: PMC1802007 From the Cover:
Antipsychotic drug-induced weight gain mediated by histamine H1 receptor-linked activation of hypothalamic AMP-kinase Sangwon F. Kim, Alex S. Huang, Adele M. Snowman, Cory Teuscher, and Solomon H. Snyder PMCID: PMC1805549 Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-β signaling Mitsunobu R. Kano, Younsoo Bae, Caname Iwata, Yasuyuki Morishita, Masakazu Yashiro, Masako Oka, Tomoko Fujii, Akiyoshi Komuro, Kunihiko Kiyono, Michio Kaminishi, Kosei Hirakawa, Yasuyoshi Ouchi, Nobuhiro Nishiyama, Kazunori Kataoka, and Kohei Miyazono PMCID: PMC1800736 Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma Liliana Soroceanu, Samir Kharbanda, Ruihuan Chen, Robert H. Soriano, Ken Aldape, Anjan Misra, Jiping Zha, William F. Forrest, Janice M. Nigro, Zora Modrusan, Burt G. Feuerstein, and Heidi S. Phillips PMCID: PMC1802005 Dysfunction of GABAA receptor glycolysis-dependent modulation in human partial epilepsy Jacques J. Laschet, Irène Kurcewicz, Frédéric Minier, Suzanne Trottier, Jamila Khallou-Laschet, Jacques Louvel, Sylvain Gigout, Baris Turak, Arnaud Biraben, Jean-Marie Scarabin, Bertrand Devaux, Patrick Chauvel, and René Pumain PMCID: PMC1805601 Mice expressing a humanized form of VEGF-A may provide insights into the safety and efficacy of anti-VEGF antibodies Hans-Peter Gerber, Xiumin Wu, Lanlan Yu, Christian Wiesmann, Xiao Huan Liang, Chingwei V. Lee, Germaine Fuh, Christine Olsson, Lisa Damico, David Xie, Y. Gloria Meng, Johnny Gutierrez, Racquel Corpuz, Bing Li, Linda Hall, Linda Rangell, Ron Ferrando, Henry Lowman, Franklin Peale, and Napoleone Ferrara PMCID: PMC1805509 Strategy for reversing resistance to a single anticancer agent in human prostate and pancreatic carcinomas Irina V. Lebedeva, Ilyas Washington, Devanand Sarkar, Jennifer A. Clark, Robert L. Fine, Paul Dent, David T. Curiel, Nicholas J. Turro, and Paul B. Fisher PMCID: PMC1805584 c-Myc-mediated genomic instability proceeds via a megakaryocytic endomitosis pathway involving Gp1bα Youjun Li, Jie Lu, and Edward V. Prochownik PMCID: PMC1805544 Microbiology Selective retention of herpes simplex virus-specific T cells in latently infected human trigeminal ganglia Georges M. G. M. Verjans, Rogier Q. Hintzen, Jessica M. van Dun, Angelique Poot, Johannes C. Milikan, Jon D. Laman, Anton W. Langerak, Paul R. Kinchington, and Albert D. M. E. Osterhaus PMCID: PMC1805572 SseL, a Salmonella deubiquitinase required for macrophage killing and virulence Anne Rytkönen, John Poh, Junkal Garmendia, Cliona Boyle, Arthur Thompson, Mei Liu, Paul Freemont, Jay C. D. Hinton, and David W. Holden PMCID: PMC1802004 A eukaryotic-type Ser/Thr kinase in Enterococcus faecalis mediates antimicrobial resistance and intestinal persistence Christopher J. Kristich, Carol L. Wells, and Gary M. Dunny PMCID: PMC1805595 Point mutations in TOR confer Rheb-independent growth in fission yeast and nutrient-independent mammalian TOR signaling in mammalian cells Jun Urano, Tatsuhiro Sato, Tomohiko Matsuo, Yoko Otsubo, Masayuki Yamamoto, and Fuyuhiko Tamanoi PMCID: PMC1805553 c-Src protein kinase inhibitors block assembly and maturation of dengue virus J. J. H. Chu and Priscilla L. Yang PMCID: PMC1805510 A polyphosphate kinase 1 (ppk1) mutant of Pseudomonas aeruginosa exhibits multiple ultrastructural and functional defects Cresson D. Fraley, M. Harunur Rashid, Sam S. K. Lee, Rebecca Gottschalk, Janine Harrison, Pauline J. Wood, Michael R. W. Brown, and Arthur Kornberg PMCID: PMC1803759 Neuroscience Cortical pooling algorithms for judging global motion direction Ben S. Webb, Timothy Ledgeway, and Paul V. McGraw PMCID: PMC1805614 Moonlight shifts the endogenous clock of Drosophila melanogaster Wolfgang Bachleitner, Lena Kempinger, Corinna Wülbeck, Dirk Rieger, and Charlotte Helfrich-Förster PMCID: PMC1805525 Impact of spatiotemporally correlated images on the structure of memory Alberto Bernacchia and Daniel J. Amit PMCID: PMC1805598 Developmental hearing loss eliminates long-term potentiation in the auditory cortex Vibhakar C. Kotak, Andrew D. Breithaupt, and Dan H. Sanes PMCID: PMC1805556 Retrospective and prospective responses arising in a modeled hippocampus during maze navigation by a brain-based device Jason G. Fleischer, Joseph A. Gally, Gerald M. Edelman, and Jeffrey L. Krichmar PMCID: PMC1802731 Cellular scaling rules for primate brains Suzana Herculano-Houzel, Christine E. Collins, Peiyan Wong, and Jon H. Kaas PMCID: PMC1805542 Apoptotic surge of potassium currents is mediated by p38 phosphorylation of Kv2.1 Patrick T. Redman, Kai He, Karen A. Hartnett, Bahiyya S. Jefferson, Linda Hu, Paul A. Rosenberg, Edwin S. Levitan, and Elias Aizenman PMCID: PMC1805571 The molecular basis of CO2 reception in Drosophila Jae Young Kwon, Anupama Dahanukar, Linnea A. Weiss, and John R. Carlson PMCID: PMC1805529 Regulation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor trafficking through PKA phosphorylation of the Glu receptor 1 subunit Heng-Ye Man, Yoko Sekine-Aizawa, and Richard L. Huganir PMCID: PMC1805611 The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease Günter U. Höglinger, Joshua J. Breunig, Candan Depboylu, Caroline Rouaux, Patrick P. Michel, Daniel Alvarez-Fischer, Anne-Laurence Boutillier, James DeGregori, Wolfgang H. Oertel, Pasko Rakic, Etienne C. Hirsch, and Stéphane Hunot PMCID: PMC1805567 Phosphorylation of tau antagonizes apoptosis by stabilizing β-catenin, a mechanism involved in Alzheimer's neurodegeneration Hong-Lian Li, Hai-Hong Wang, Shi-Jie Liu, Yan-Qiu Deng, Yong-Jie Zhang, Qing Tian, Xiao-Chuan Wang, Xiao-Qian Chen, Ying Yang, Jia-Yu Zhang, Qun Wang, Huaxi Xu, Francesca-Fang Liao, and Jian-Zhi Wang PMCID: PMC1805527 Pharmacology Brain protection using autologous bone marrow cell, metalloproteinase inhibitors, and metabolic treatment in cerebral ischemia Andrew H. Baker, Vincenzo Sica, Lorraine M. Work, Sharon Williams-Ignarro, Filomena de Nigris, Lilach O. Lerman, Amelia Casamassimi, Alessandro Lanza, Concetta Schiano, Monica Rienzo, Louis J. Ignarro, and Claudio Napoli PMCID: PMC1805552 Monitoring the function of membrane transport proteins in detergent-solubilized form Matthias Quick and Jonathan A. Javitch PMCID: PMC1805550 Physiology Defective glycerol metabolism in aquaporin 9 (AQP9) knockout mice Aleksandra M. Rojek, Mariusz T. Skowronski, Ernst-Martin Füchtbauer, Annette C. Füchtbauer, Robert A. Fenton, Peter Agre, Jørgen Frøkiær, and Søren Nielsen PMCID: PMC1805577 Male fetal germ cells are targets for androgens that physiologically inhibit their proliferation Jorge Merlet, Chrystèle Racine, Evelyne Moreau, Stéphanie G. Moreno, and René Habert PMCID: PMC1805536 Interaction between transcellular and paracellular water transport pathways through Aquaporin 5 and the tight junction complex Jitesh D. Kawedia, Michelle L. Nieman, Gregory P. Boivin, James E. Melvin, Ken-Ichiro Kikuchi, Arthur R. Hand, John N. Lorenz, and Anil G. Menon PMCID: PMC1802728 Plant Biology Single-site mutations in the carboxyltransferase domain of plastid acetyl-CoA carboxylase confer resistance to grass-specific herbicides Wenjie Liu, Dion K. Harrison, Dominika Chalupska, Piotr Gornicki, Chris C. O'Donnell, Steve W. Adkins, Robert Haselkorn, and Richard R. Williams PMCID: PMC1802000 Small RNA-mediated chromatin silencing directed to the 3′ region of the Arabidopsis gene encoding the developmental regulator, FLC Szymon Swiezewski, Pedro Crevillen, Fuquan Liu, Joseph R. Ecker, Andrzej Jerzmanowski, and Caroline Dean PMCID: PMC1805594 Arabidopsis plasma membrane protein crucial for Ca2+ influx and touch sensing in roots Yuko Nakagawa, Takeshi Katagiri, Kazuo Shinozaki, Zhi Qi, Hitoshi Tatsumi, Takuya Furuichi, Akio Kishigami, Masahiro Sokabe, Itaru Kojima, Shusei Sato, Tomohiko Kato, Satoshi Tabata, Kazuko Iida, Asuka Terashima, Masataka Nakano, Mitsunobu Ikeda, Takuya Yamanaka, and Hidetoshi Iida PMCID: PMC1802001 Divergent functions of VTI12 and VTI11 in trafficking to storage and lytic vacuoles in Arabidopsis Maite Sanmartín, Angel Ordóñez, Eun Ju Sohn, Stephanie Robert, José Juán Sánchez-Serrano, Marci A. Surpin, Natasha V. Raikhel, and Enrique Rojo PMCID: PMC1805581 Social Sciences Anthropology 4,300-Year-old chimpanzee sites and the origins of percussive stone technology Julio Mercader, Huw Barton, Jason Gillespie, Jack Harris, Steven Kuhn, Robert Tyler, and Christophe Boesch PMCID: PMC1805589 Confirmation of Neanderthal/modern human interstratification at the Chatelperronian type-site Paul Mellars, Brad Gravina, and Christopher Bronk Ramsey PMCID: PMC1805566 The strange case of the earliest silver extraction by European colonists in the New World A. M. Thibodeau, D. J. Killick, J. Ruiz, J. T. Chesley, K. Deagan, J. M. Cruxent, and W. Lyman PMCID: PMC1805524 Sustainability Science Single-site mutations in the carboxyltransferase domain of plastid acetyl-CoA carboxylase confer resistance to grass-specific herbicides Wenjie Liu, Dion K. Harrison, Dominika Chalupska, Piotr Gornicki, Chris C. O'Donnell, Steve W. Adkins, Robert Haselkorn, and Richard R. Williams PMCID: PMC1802000 Correction Correction for Borodinsky and Spitzer, Activity-dependent neurotransmitter-receptor matching at the neuromuscular junction PMCID: PMC1805541 Corrects: Laura N. Borodinsky, et al. Activity-dependent neurotransmitter-receptor matching at the neuromuscular junction. Proc Natl Acad Sci U S A. 2007 January 2; 104(1): 335–340. Retractions Retraction for Ma and Chang, Structure of the multidrug resistance efflux transporter EmrE from Escherichia coli Che Ma and Geoffrey Chang PMCID: PMC1805606 Retracts: Che Ma, et al. Structure of the multidrug resistance efflux transporter EmrE from Escherichia coli. Proc Natl Acad Sci U S A. 2004 March 2; 101(9): 2852–2857. Retraction for Gianni et al., The herpesvirus glycoproteins B and H·L are sequentially recruited to the receptor-bound gD to effect membrane fusion at virus entry Tatiana Gianni, Cristina Forghieri, and Gabriella Campadelli-Fiume PMCID: PMC1805600 Retracts: Tatiana Gianni, et al. The herpesvirus glycoproteins B and H·L are sequentially recruited to the receptor-bound gD to effect membrane fusion at virus entry. Proc Natl Acad Sci U S A. 2006 September 26; 103(39): 14572–14577. |
