| | This journal provides immediate access to some articles. Hypothesis The potential role of ribosomal frameshifting in generating aberrant proteins implicated in neurodegenerative diseases Norma M. Wills and John F. Atkins PMCID: PMC1484430 Letter to the Editor An mRNA sequence derived from a programmed frameshifting signal decreases codon discrimination during translation initiation Ana Raman, Carla Guarraia, Dwayne Taliaferro, Guillaume Stahl, and Philip J. Farabaugh PMCID: PMC1484443 Reports Post-transcriptional regulation of microRNA expression Gregor Obernosterer, Philipp J.F. Leuschner, Mattias Alenius, and Javier Martinez PMCID: PMC1484437 The role of RNA structure in the interaction of U1A protein with U1 hairpin II RNA Michael J. Law, Andrew J. Rice, Patti Lin, and Ite A. Laird-Offringa PMCID: PMC1484440 Articles Widespread siRNA “off-target” transcript silencing mediated by seed region sequence complementarity Aimee L. Jackson, Julja Burchard, Janell Schelter, B. Nelson Chau, Michele Cleary, Lee Lim, and Peter S. Linsley PMCID: PMC1484447 Off-target effects by siRNA can induce toxic phenotype Yuriy Fedorov, Emily M. Anderson, Amanda Birmingham, Angela Reynolds, Jon Karpilow, Kathryn Robinson, Devin Leake, William S. Marshall, and Anastasia Khvorova PMCID: PMC1484448 Position-specific chemical modification of siRNAs reduces “off-target” transcript silencing Aimee L. Jackson, Julja Burchard, Devin Leake, Angela Reynolds, Janell Schelter, Jie Guo, Jason M. Johnson, Lee Lim, Jon Karpilow, Kim Nichols, William Marshall, Anastasia Khvorova, and Peter S. Linsley PMCID: PMC1484422 Conserved zinc fingers mediate multiple functions of ZFP100, a U7snRNP associated protein Eric J. Wagner, Jason K. Ospina, Yue Hu, Miroslav Dundr, A. Gregory Matera, and William F. Marzluff PMCID: PMC1484431 RNA editing complex interactions with a site for full-round U deletion in Trypanosoma brucei
Anastasia Sacharidou, Catherine Cifuentes-Rojas, Kari Halbig, Alfredo Hernandez, Lawrence J. Dangott, Monica De Nova-Ocampo, and Jorge Cruz-Reyes PMCID: PMC1484423 30S ribosomal subunits can be assembled in vivo without primary binding ribosomal protein S15 Mikhail Bubunenko, Alexey Korepanov, Donald L. Court, Indu Jagannathan, Daniel Dickinson, Biswajoy Roy Chaudhuri, Maria B. Garber, and Gloria M. Culver PMCID: PMC1484426 Functional conformations of the L11–ribosomal RNA complex revealed by correlative analysis of cryo-EM and molecular dynamics simulations Wen Li, Jayati Sengupta, Bimal K. Rath, and Joachim Frank PMCID: PMC1484425 tRNA regulation of gene expression: Interactions of an mRNA 5′-UTR with a regulatory tRNA Audrey R. Nelson, Tina M. Henkin, and Paul F. Agris PMCID: PMC1484421 Characterization of GE82832, a peptide inhibitor of translocation interacting with bacterial 30S ribosomal subunits Letizia Brandi, Attilio Fabbretti, Michele Di Stefano, Ameriga Lazzarini, Monica Abbondi, and Claudio O. Gualerzi PMCID: PMC1484444 Use of targetrons to disrupt essential and nonessential genes in Staphylococcus aureus reveals temperature sensitivity of Ll.LtrB group II intron splicing Jun Yao, Jin Zhong, Yuan Fang, Edward Geisinger, Richard P. Novick, and Alan M. Lambowitz PMCID: PMC1484445 Chemical rescue, multiple ionizable groups, and general acid–base catalysis in the HDV genomic ribozyme Anne T. Perrotta, Timothy S. Wadkins, and Michael D. Been PMCID: PMC1484427 RBP16 stimulates trypanosome RNA editing in vitro at an early step in the editing reaction Melissa M. Miller, Kari Halbig, Jorge Cruz-Reyes, and Laurie K. Read PMCID: PMC1484434 Analysis of a 3′-translation enhancer in a tombusvirus: A dynamic model for RNA–RNA interactions of mRNA termini Marc R. Fabian and K. Andrew White PMCID: PMC1484428 Evolutionary conservation of a functionally important backbone phosphate group critical for aminoacylation of histidine tRNAs Abbey E. Rosen, Bonnie S. Brooks, Ethan Guth, Christopher S. Francklyn, and Karin Musier-Forsyth PMCID: PMC1484442 Yeast transcripts cleaved by an internal ribozyme provide new insight into the role of the cap and poly(A) tail in translation and mRNA decay Stacie Meaux and Ambro Van Hoof PMCID: PMC1484436 Close spacing of AUG initiation codons confers dicistronic character on a eukaryotic mRNA Daiki Matsuda and Theo W. Dreher PMCID: PMC1484435 Dimerization of ADAR2 is mediated by the double-stranded RNA binding domain Hanne Poulsen, Rasmus Jorgensen, Anders Heding, Finn C. Nielsen, Bjarne Bonven, and Jan Egebjerg PMCID: PMC1484439 A subset of Mer1p-dependent introns requires Bud13p for splicing activation and nuclear retention Frederick W. Scherrer, Jr and Marc Spingola PMCID: PMC1484446 Differential association of protein subunits with the human RNase MRP and RNase P complexes Tim J.M. Welting, Bastiaan J. Kikkert, Walther J. van Venrooij, and Ger J.M. Pruijn PMCID: PMC1484433 Identification of small Hfq-binding RNAs in Listeria monocytogenes
Janne K. Christiansen, Jesper S. Nielsen, Tine Ebersbach, Poul Valentin-Hansen, Lotte Søgaard-Andersen, and Birgitte H. Kallipolitis PMCID: PMC1484441 Elongation factor 1α binds to the region of the metallothionein-1 mRNA implicated in perinuclear localization—importance of an internal stem–loop Ian Mickleburgh, Hervé Chabanon, David Nury, Kunbo Fan, Brian Burtle, Zofia Chrzanowska-Lightowlers, and John Hesketh PMCID: PMC1484432 mRNA localization to the mitochondrial surface allows the efficient translocation inside the organelle of a nuclear recoded ATP6 protein Valérie Kaltimbacher, Crystel Bonnet, Gaëlle Lecoeuvre, Valérie Forster, José-Alain Sahel, and Marisol Corral-Debrinski PMCID: PMC1484424 The network of protein–protein interactions within the human U4/U6.U5 tri-snRNP Sunbin Liu, Reinhard Rauhut, Hans-Peter Vornlocher, and Reinhard Lührmann PMCID: PMC1484429 Method Stearylated octaarginine and artificial virus-like particles for transfection of siRNA into primary rat neurons Lars Tönges, Paul Lingor, Roman Egle, Gunnar P.H. Dietz, Alfred Fahr, and Mathias Bähr PMCID: PMC1484438 |
