| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2006 June 6; 103(23): 8573–8574. doi: 10.1073/iti2306103.PMCID: PMC1482620 Commentary Two modes of pathogen recognition by plants Jeffery L. Dangl and John M. McDowell PMCID: PMC1482621 Physical Sciences Applied Mathematics From the Cover:
Modularity and community structure in networks M. E. J. Newman PMCID: PMC1482622 Understanding bistability in complex enzyme-driven reaction networks Gheorghe Craciun, Yangzhong Tang, and Martin Feinberg PMCID: PMC1592242 Applied Physical Sciences Evaluation of synthetic linear motor-molecule actuation energetics Branden Brough, Brian H. Northrop, Jacob J. Schmidt, Hsian-Rong Tseng, Kendall N. Houk, J. Fraser Stoddart, and Chih-Ming Ho PMCID: PMC1482623 Soft-lithographic replication of 3D microstructures with closed loops Christopher N. LaFratta, Linjie Li, and John T. Fourkas PMCID: PMC1464799 Chemistry A hint for the function of human Sco1 from different structures Lucia Banci, Ivano Bertini, Vito Calderone, Simone Ciofi-Baffoni, Stefano Mangani, Manuele Martinelli, Peep Palumaa, and Shenlin Wang PMCID: PMC1482625 Bacteriorhodopsin (bR) as an electronic conduction medium: Current transport through bR-containing monolayers Yongdong Jin, Noga Friedman, Mordechai Sheves, Tao He, and David Cahen PMCID: PMC1482626 Adenine and 2-aminopurine: Paradigms of modern theoretical photochemistry Luis Serrano-Andrés, Manuela Merchán, and Antonio C. Borin PMCID: PMC1482641 Engineering Imaging breast adipose and fibroglandular tissue molecular signatures by using hybrid MRI-guided near-infrared spectral tomography Ben Brooksby, Brian W. Pogue, Shudong Jiang, Hamid Dehghani, Subhadra Srinivasan, Christine Kogel, Tor D. Tosteson, John Weaver, Steven P. Poplack, and Keith D. Paulsen PMCID: PMC1482663 Geology Sulfolipids dramatically decrease phosphorus demand by picocyanobacteria in oligotrophic marine environments Benjamin A. S. Van Mooy, Gabrielle Rocap, Helen F. Fredricks, Colleen T. Evans, and Allan H. Devol PMCID: PMC1482627 Physics Water properties from first principles: Simulations by a general-purpose quantum mechanical polarizable force field A. G. Donchev, N. G. Galkin, A. A. Illarionov, O. V. Khoruzhii, M. A. Olevanov, V. D. Ozrin, M. V. Subbotin, and V. I. Tarasov PMCID: PMC1466545 Biological Sciences Applied Biological Sciences Multiple and time-scheduled in situ DNA delivery mediated by β-cyclodextrin embedded in a polyelectrolyte multilayer N. Jessel, M. Oulad-Abdelghani, F. Meyer, P. Lavalle, Y. Haîkel, P. Schaaf, and J.-C. Voegel PMCID: PMC1482629 Biochemistry From the Cover:
Regulation of insect steroid hormone biosynthesis by innervating peptidergic neurons Naoki Yamanaka, Dušan Žitňan, Young-Joon Kim, Michael E. Adams, Yue-Jin Hua, Yusuke Suzuki, Minoru Suzuki, Akemi Suzuki, Honoo Satake, Akira Mizoguchi, Kiyoshi Asaoka, Yoshiaki Tanaka, and Hiroshi Kataoka PMCID: PMC1482630 Butyrylcholinesterase attenuates amyloid fibril formation in vitro Sophia Diamant, Erez Podoly, Assaf Friedler, Hagai Ligumsky, Oded Livnah, and Hermona Soreq PMCID: PMC1482631 Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor Almer M. van der Sloot, Vicente Tur, Eva Szegezdi, Margaret M. Mullally, Robbert H. Cool, Afshin Samali, Luis Serrano, and Wim J. Quax PMCID: PMC1482632 tRNAHis guanylyltransferase catalyzes a 3′-5′ polymerization reaction that is distinct from G−1 addition Jane E. Jackman and Eric M. Phizicky PMCID: PMC1482633 How azide inhibits ATP hydrolysis by the F-ATPases Matthew W. Bowler, Martin G. Montgomery, Andrew G. W. Leslie, and John E. Walker PMCID: PMC1469772 In vivo incorporation of multiple unnatural amino acids through nonsense and frameshift suppression Erik A. Rodriguez, Henry A. Lester, and Dennis A. Dougherty PMCID: PMC1482635 Thionein can serve as a reducing agent for the methionine sulfoxide reductases Daphna Sagher, David Brunell, J. Fielding Hejtmancik, Marc Kantorow, Nathan Brot, and Herbert Weissbach PMCID: PMC1592241 The Mycobacterium tuberculosis LipB enzyme functions as a cysteine/lysine dyad acyltransferase Qingjun Ma, Xin Zhao, Ali Nasser Eddine, Arie Geerlof, Xinping Li, John E. Cronan, Stefan H. E. Kaufmann, and Matthias Wilmanns PMCID: PMC1472244 Structural insights into stereochemical inversion by diaminopimelate epimerase: An antibacterial drug target Bindu Pillai, Maia M. Cherney, Christopher M. Diaper, Andrew Sutherland, John S. Blanchard, John C. Vederas, and Michael N. G. James PMCID: PMC1482637 Zinc binding to a regulatory zinc-sensing domain monitored in vivo by using FRET Wei Qiao, Michelle Mooney, Amanda J. Bird, Dennis R. Winge, and David J. Eide PMCID: PMC1482638 Biophysics Bacteriorhodopsin (bR) as an electronic conduction medium: Current transport through bR-containing monolayers Yongdong Jin, Noga Friedman, Mordechai Sheves, Tao He, and David Cahen PMCID: PMC1482626 Water properties from first principles: Simulations by a general-purpose quantum mechanical polarizable force field A. G. Donchev, N. G. Galkin, A. A. Illarionov, O. V. Khoruzhii, M. A. Olevanov, V. D. Ozrin, M. V. Subbotin, and V. I. Tarasov PMCID: PMC1466545 From the Cover:
Myosin-V is a mechanical ratchet J. Christof M. Gebhardt, Anabel E.-M. Clemen, Johann Jaud, and Matthias Rief PMCID: PMC1482639 Conductance of a biomolecular wire Iris Visoly-Fisher, Kayvon Daie, Yuichi Terazono, Christian Herrero, Fernando Fungo, Luis Otero, Edgardo Durantini, Juana J. Silber, Leonides Sereno, Devens Gust, Thomas A. Moore, Ana L. Moore, and Stuart M. Lindsay PMCID: PMC1482640 Adenine and 2-aminopurine: Paradigms of modern theoretical photochemistry Luis Serrano-Andrés, Manuela Merchán, and Antonio C. Borin PMCID: PMC1482641 Cell Biology Understanding bistability in complex enzyme-driven reaction networks Gheorghe Craciun, Yangzhong Tang, and Martin Feinberg PMCID: PMC1592242 From the Cover:
Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging Dale K. Shumaker, Thomas Dechat, Alexander Kohlmaier, Stephen A. Adam, Matthew R. Bozovsky, Michael R. Erdos, Maria Eriksson, Anne E. Goldman, Satya Khuon, Francis S. Collins, Thomas Jenuwein, and Robert D. Goldman PMCID: PMC1472659 Accumulation of small murine minor satellite transcripts leads to impaired centromeric architecture and function Haniaa Bouzinba-Segard, Adeline Guais, and Claire Francastel PMCID: PMC1482643 Bending a membrane: How clathrin affects budding Lars Hinrichsen, Anika Meyerholz, Stephanie Groos, and Ernst J. Ungewickell PMCID: PMC1482644 Developmental Biology Myogenic factors that regulate expression of muscle-specific microRNAs Prakash K. Rao, Roshan M. Kumar, Mina Farkhondeh, Scott Baskerville, and Harvey F. Lodish PMCID: PMC1482645 Precraniate origin of cranial motoneurons Héloïse D. Dufour, Zoubida Chettouh, Carole Deyts, Renaud de Rosa, Christo Goridis, Jean-Stéphane Joly, and Jean-François Brunet PMCID: PMC1482646 Ecology The allometry of ornaments and weapons Astrid Kodric-Brown, Richard M. Sibly, and James H. Brown PMCID: PMC1470970 Scaling the metabolic balance of the oceans Ángel López-Urrutia, Elena San Martin, Roger P. Harris, and Xabier Irigoien PMCID: PMC1482648 Environmental Sciences Isotopic evidence for large gaseous nitrogen losses from tropical rainforests Benjamin Z. Houlton, Daniel M. Sigman, and Lars O. Hedin PMCID: PMC1469773 Evolution Mitochondrial genome of Trichoplax adhaerens supports Placozoa as the basal lower metazoan phylum Stephen L. Dellaporta, Anthony Xu, Sven Sagasser, Wolfgang Jakob, Maria A. Moreno, Leo W. Buss, and Bernd Schierwater PMCID: PMC1470968 Amplification of DNA from preserved specimens shows blowflies were preadapted for the rapid evolution of insecticide resistance C. J. Hartley, R. D. Newcomb, R. J. Russell, C. G. Yong, J. R. Stevens, D. K. Yeates, J. La Salle, and J. G. Oakeshott PMCID: PMC1482651 Anthracothere dental anatomy reveals a late Miocene Chado-Libyan bioprovince Fabrice Lihoreau, Jean-Renaud Boisserie, Laurent Viriot, Yves Coppens, Andossa Likius, Hassane Taisso Mackaye, Paul Tafforeau, Patrick Vignaud, and Michel Brunet PMCID: PMC1482652 Genetics Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions Hiroshi Saeki, Nicolas Siaud, Nicole Christ, Wouter W. Wiegant, Paul P. W. van Buul, Mingguang Han, Małgorzata Z. Zdzienicka, Jeremy M. Stark, and Maria Jasin PMCID: PMC1482653 A metabolic network in the evolutionary context: Multiscale structure and modularity Victor Spirin, Mikhail S. Gelfand, Andrey A. Mironov, and Leonid A. Mirny PMCID: PMC1482654 Cellular inhibitors of long interspersed element 1 and Alu retrotransposition Hal P. Bogerd, Heather L. Wiegand, Amy E. Hulme, José L. Garcia-Perez, K. Sue O’Shea, John V. Moran, and Bryan R. Cullen PMCID: PMC1482655 Mouse telocentric sequences reveal a high rate of homogenization and possible role in Robertsonian translocation Paul Kalitsis, Belinda Griffiths, and K. H. Andy Choo PMCID: PMC1482656 Immunology The dsRNA binding site of human Toll-like receptor 3 Jessica K. Bell, Janine Askins, Pamela R. Hall, David R. Davies, and David M. Segal PMCID: PMC1482657 Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation Kevin M. McBride, Anna Gazumyan, Eileen M. Woo, Vasco M. Barreto, Davide F. Robbiani, Brian T. Chait, and Michel C. Nussenzweig PMCID: PMC1482658 Plant-derived anti-Lewis Y mAb exhibits biological activities for efficient immunotherapy against human cancer cells Robert Brodzik, Magdalena Glogowska, Katarzyna Bandurska, Monika Okulicz, Deepali Deka, Kisung Ko, Joke van der Linden, Jeanette H. W. Leusen, Natalia Pogrebnyak, Maxim Golovkin, Zenon Steplewski, and Hilary Koprowski PMCID: PMC1482659 A peptide based on the complementarity-determining region 1 of an autoantibody ameliorates lupus by up-regulating CD4+CD25+ cells and TGF-β Amir Sharabi, Heidy Zinger, Maya Zborowsky, Zev M. Sthoeger, and Edna Mozes PMCID: PMC1482660 Contribution of IL-18 to atopic-dermatitis-like skin inflammation induced by Staphylococcus aureus product in mice Makoto Terada, Hiroko Tsutsui, Yasutomo Imai, Koubun Yasuda, Hitoshi Mizutani, Kiyofumi Yamanishi, Masato Kubo, Kiyoshi Matsui, Hajime Sano, and Kenji Nakanishi PMCID: PMC1482661 Medical Sciences Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer Ruben Agrelo, Wen-Hsing Cheng, Fernando Setien, Santiago Ropero, Jesus Espada, Mario F. Fraga, Michel Herranz, Maria F. Paz, Montserrat Sanchez-Cespedes, Maria Jesus Artiga, David Guerrero, Antoni Castells, Cayetano von Kobbe, Vilhelm A. Bohr, and Manel Esteller PMCID: PMC1466544 Imaging breast adipose and fibroglandular tissue molecular signatures by using hybrid MRI-guided near-infrared spectral tomography Ben Brooksby, Brian W. Pogue, Shudong Jiang, Hamid Dehghani, Subhadra Srinivasan, Christine Kogel, Tor D. Tosteson, John Weaver, Steven P. Poplack, and Keith D. Paulsen PMCID: PMC1482663 Microbiology Sulfolipids dramatically decrease phosphorus demand by picocyanobacteria in oligotrophic marine environments Benjamin A. S. Van Mooy, Gabrielle Rocap, Helen F. Fredricks, Colleen T. Evans, and Allan H. Devol PMCID: PMC1482627 A hybrid two-component system protein of a prominent human gut symbiont couples glycan sensing in vivo to carbohydrate metabolism Erica D. Sonnenburg, Justin L. Sonnenburg, Jill K. Manchester, Elizabeth E. Hansen, Herbert C. Chiang, and Jeffrey I. Gordon PMCID: PMC1472243 Plasmodium falciparum ensures its amino acid supply with multiple acquisition pathways and redundant proteolytic enzyme systems Jun Liu, Eva S. Istvan, Ilya Y. Gluzman, Julia Gross, and Daniel E. Goldberg PMCID: PMC1470969 Bases of biocontrol: Sequence predicts synthesis and mode of action of agrocin 84, the Trojan Horse antibiotic that controls crown gall Jung-Gun Kim, Byoung Keun Park, Sung-Uk Kim, Doil Choi, Baek Hie Nahm, Jae Sun Moon, John S. Reader, Stephen K. Farrand, and Ingyu Hwang PMCID: PMC1482666 Neuroscience β-Amyloid infusion results in delayed and age-dependent learning deficits without role of inflammation or β-amyloid deposits Tarja Malm, Michael Ort, Leena Tähtivaara, Niko Jukarainen, Gundars Goldsteins, Jukka Puoliväli, Antti Nurmi, Raimo Pussinen, Toni Ahtoniemi, Taina-Kaisa Miettinen, Katja Kanninen, Suvi Leskinen, Nina Vartiainen, Juha Yrjänheikki, Reino Laatikainen, Marni E. Harris-White, Milla Koistinaho, Sally A. Frautschy, Jan Bures, and Jari Koistinaho PMCID: PMC1482667 Cre recombinase-mediated restoration of nigrostriatal dopamine in dopamine-deficient mice reverses hypophagia and bradykinesia Thomas S. Hnasko, Francisco A. Perez, Alex D. Scouras, Elizabeth A. Stoll, Samuel D. Gale, Serge Luquet, Paul E. M. Phillips, Eric J. Kremer, and Richard D. Palmiter PMCID: PMC1466546 Polymerization of hyperphosphorylated tau into filaments eliminates its inhibitory activity Alejandra del C. Alonso, Bin Li, Inge Grundke-Iqbal, and Khalid Iqbal PMCID: PMC1482669 Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domains Hee Jung Chung, Yuh Nung Jan, and Lily Y. Jan PMCID: PMC1472242 Extending the effects of spike-timing-dependent plasticity to behavioral timescales Patrick J. Drew and L. F. Abbott PMCID: PMC1470971 Physiology Phosphatidylinositol 3-kinase mediates activation of ATM by high NaCl and by ionizing radiation: Role in osmoprotective transcriptional regulation Carlos E. Irarrazabal, Maurice B. Burg, Stephen G. Ward, and Joan D. Ferraris PMCID: PMC1482672 Plant Biology From the Cover:
Direct protein interaction underlies gene-for-gene specificity and coevolution of the flax resistance genes and flax rust avirulence genes Peter N. Dodds, Gregory J. Lawrence, Ann-Maree Catanzariti, Trazel Teh, Ching-I. A. Wang, Michael A. Ayliffe, Bostjan Kobe, and Jeffrey G. Ellis PMCID: PMC1482673 Fragments of ATP synthase mediate plant perception of insect attack Eric A. Schmelz, Mark J. Carroll, Sherry LeClere, Stephen M. Phipps, Julia Meredith, Prem S. Chourey, Hans T. Alborn, and Peter E. A. Teal PMCID: PMC1482674 Psychology Limbic hyperactivation during processing of neutral facial expressions in children with bipolar disorder Brendan A. Rich, Deborah T. Vinton, Roxann Roberson-Nay, Rebecca E. Hommer, Lisa H. Berghorst, Erin B. McClure, Stephen J. Fromm, Daniel S. Pine, and Ellen Leibenluft PMCID: PMC1482675 Correction Correction for Satou et al., HTLV-I basic leucine zipper factor gene mRNA supports proliferation of adult T cell leukemia cells PMCID: PMC1482676 Corrects: Yorifumi Satou, et al. HTLV-I basic leucine zipper factor gene mRNA supports proliferation of adult T cell leukemia cells. Proc Natl Acad Sci U S A. 2006 January 17; 103(3): 720–725. |
