| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2006 May 30; 103(22): 8301–8302. doi: 10.1073/iti2206103.PMCID: PMC1482486 Commentaries TL1A: A mediator of gut inflammation Howard A. Young and Michael G. Tovey PMCID: PMC1482487 Evolving stealth: Genetic adaptation of Pseudomonas aeruginosa during cystic fibrosis infections Dao Nguyen and Pradeep K. Singh PMCID: PMC1482488 Alcohol-sensitive GABA receptors and alcohol antagonists Steven M. Paul PMCID: PMC1482489 Physical Sciences Applied Mathematics Distinct metastable atmospheric regimes despite nearly Gaussian statistics: A paradigm model Andrew J. Majda, Christian L. Franzke, Alexander Fischer, and Daniel T. Crommelin PMCID: PMC1482490 Applied Physical Sciences From the Cover:
Flows driven by flagella of multicellular organisms enhance long-range molecular transport Martin B. Short, Cristian A. Solari, Sujoy Ganguly, Thomas R. Powers, John O. Kessler, and Raymond E. Goldstein PMCID: PMC1482491 Chemistry The delivery of copper for thylakoid import observed by NMR Lucia Banci, Ivano Bertini, Simone Ciofi-Baffoni, Nikolaos G. Kandias, Nigel J. Robinson, Georgios A. Spyroulias, Xun-Cheng Su, Stephen Tottey, and Murugendra Vanarotti PMCID: PMC1482492 From the Cover:
Evidence of hollow golden cages Satya Bulusu, Xi Li, Lai-Sheng Wang, and Xiao Cheng Zeng PMCID: PMC1482493 Assessing implicit models for nonpolar mean solvation forces: The importance of dispersion and volume terms Jason A. Wagoner and Nathan A. Baker PMCID: PMC1482494 Geology Critical bifurcation of shallow microtidal landforms in tidal flats and salt marshes Sergio Fagherazzi, Luca Carniello, Luigi D'Alpaos, and Andrea Defina PMCID: PMC1482495 Biological Sciences Biochemistry Locating active-site hydrogen atoms in d-xylose isomerase: Time-of-flight neutron diffraction Amy K. Katz, Xinmin Li, H. L. Carrell, B. Leif Hanson, Paul Langan, Leighton Coates, Benno P. Schoenborn, Jenny P. Glusker, and Gerard J. Bunick PMCID: PMC1482496 The AAA ATPase p97 links peptide N-glycanase to the endoplasmic reticulum-associated E3 ligase autocrine motility factor receptor Guangtao Li, Gang Zhao, Xiaoke Zhou, Hermann Schindelin, and William J. Lennarz PMCID: PMC1482497 A bifunctional tRNA import receptor from Leishmania mitochondria Srikanta Goswami, Gunjan Dhar, Saikat Mukherjee, Bidesh Mahata, Saibal Chatterjee, Pratik Home, and Samit Adhya PMCID: PMC1482498 Cytosolic chaperonin protects folding intermediates of Gβ from aggregation by recognizing hydrophobic β-strands Susumu Kubota, Hiroshi Kubota, and Kazuhiro Nagata PMCID: PMC1482499 An S-nitrosothiol (SNO) synthase function of hemoglobin that utilizes nitrite as a substrate Michael Angelo, David J. Singel, and Jonathan S. Stamler PMCID: PMC1482500 Biophysics Assessing implicit models for nonpolar mean solvation forces: The importance of dispersion and volume terms Jason A. Wagoner and Nathan A. Baker PMCID: PMC1482494 Stochastic models for regulatory networks of the genetic toggle switch Tianhai Tian and Kevin Burrage PMCID: PMC1482501 Conformation of the synaptobrevin transmembrane domain Mark Bowen and Axel T. Brunger PMCID: PMC1463247 Complex of linker histone H5 with the nucleosome and its implications for chromatin packing Li Fan and Victoria A. Roberts PMCID: PMC1482502 Alternative splicing in concert with protein intrinsic disorder enables increased functional diversity in multicellular organisms Pedro R. Romero, Saima Zaidi, Ya Yin Fang, Vladimir N. Uversky, Predrag Radivojac, Christopher J. Oldfield, Marc S. Cortese, Megan Sickmeier, Tanguy LeGall, Zoran Obradovic, and A. Keith Dunker PMCID: PMC1482503 Effects of surface tethering on protein folding mechanisms Miriam Friedel, Andrij Baumketner, and Joan-Emma Shea PMCID: PMC1482504 Developmental Biology The RNA-binding protein Musashi is required intrinsically to maintain stem cell identity Nicole A. Siddall, Eileen A. McLaughlin, Neisha L. Marriner, and Gary R. Hime PMCID: PMC1570104 Oxysterols stimulate Sonic hedgehog signal transduction and proliferation of medulloblastoma cells Ryan B. Corcoran and Matthew P. Scott PMCID: PMC1462959 Developmental basis for hind-limb loss in dolphins and origin of the cetacean bodyplan J. G. M. Thewissen, M. J. Cohn, L. S. Stevens, S. Bajpai, J. Heyning, and W. E. Horton, Jr. PMCID: PMC1482506 Hepatocyte nuclear factor 4α orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver Michele A. Battle, Genevieve Konopka, Fereshteh Parviz, Alexandra Lerch Gaggl, Chuhu Yang, Frances M. Sladek, and Stephen A. Duncan PMCID: PMC1482507 Ecology Dynamic fragility of oceanic coral reef ecosystems Nicholas A. J. Graham, Shaun K. Wilson, Simon Jennings, Nicholas V. C. Polunin, Jude P. Bijoux, and Jan Robinson PMCID: PMC1482508 Evolution From the Cover:
Flows driven by flagella of multicellular organisms enhance long-range molecular transport Martin B. Short, Cristian A. Solari, Sujoy Ganguly, Thomas R. Powers, John O. Kessler, and Raymond E. Goldstein PMCID: PMC1482491 A missing model in reproductive skew theory: The bordered tug-of-war Hudson Kern Reeve and Sheng-Feng Shen PMCID: PMC1482509 Genetics p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors William M. Keyes, Hannes Vogel, Maranke I. Koster, Xuecui Guo, Yi Qi, Kristin M. Petherbridge, Dennis R. Roop, Allan Bradley, and Alea A. Mills PMCID: PMC1482510 Immunology From the Cover:
Role of TL1A and its receptor DR3 in two models of chronic murine ileitis Giorgos Bamias, Margarita Mishina, Mark Nyce, William G. Ross, Giorgos Kollias, Jesus Rivera-Nieves, Theresa T. Pizarro, and Fabio Cominelli PMCID: PMC1482511 Thymic output in aged mice J. Scott Hale, Tamar E. Boursalian, Gail L. Turk, and Pamela J. Fink PMCID: PMC1482512 Foxp3+ CD25+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage Julie Cabarrocas, Cécile Cassan, Fay Magnusson, Eliane Piaggio, Lennart Mars, Jens Derbinski, Bruno Kyewski, David-Alexandre Gross, Benoit L. Salomon, Khashayarsha Khazaie, Abdelhadi Saoudi, and Roland S. Liblau PMCID: PMC1482513 Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus Leonid Gitlin, Winfried Barchet, Susan Gilfillan, Marina Cella, Bruce Beutler, Richard A. Flavell, Michael S. Diamond, and Marco Colonna PMCID: PMC1464000 Medical Sciences Anomalous levels of Cl− transporters in the hippocampal subiculum from temporal lobe epilepsy patients make GABA excitatory E. Palma, M. Amici, F. Sobrero, G. Spinelli, S. Di Angelantonio, D. Ragozzino, A. Mascia, C. Scoppetta, V. Esposito, R. Miledi, and F. Eusebi PMCID: PMC1482515 Efficient gene delivery to pancreatic islets with ultrasonic microbubble destruction technology Shuyuan Chen, Jia-huan Ding, Raffi Bekeredjian, Bing-zhi Yang, Ralph V. Shohet, Stephen A. Johnston, Hans E. Hohmeier, Christopher B. Newgard, and Paul A. Grayburn PMCID: PMC1482516 Evolution of hepatitis C viral quasispecies and hepatic injury in perinatally infected children followed prospectively Patrizia Farci, Isabella Quinti, Stefania Farci, Harvey J. Alter, Rita Strazzera, Elvia Palomba, Alessandra Coiana, Daniele Cao, Anna Maria Casadei, Ritarella Ledda, Raffaele Iorio, Angela Vegnente, Giacomo Diaz, and Pier-Angelo Tovo PMCID: PMC1482517 Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans Jean L. Chan, Giuseppe Matarese, Greeshma K. Shetty, Patricia Raciti, Iosif Kelesidis, Daniela Aufiero, Veronica De Rosa, Francesco Perna, Silvia Fontana, and Christos S. Mantzoros PMCID: PMC1482518 Microbiology From the Cover:
Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients Eric E. Smith, Danielle G. Buckley, Zaining Wu, Channakhone Saenphimmachak, Lucas R. Hoffman, David A. D’Argenio, Samuel I. Miller, Bonnie W. Ramsey, David P. Speert, Samuel M. Moskowitz, Jane L. Burns, Rajinder Kaul, and Maynard V. Olson PMCID: PMC1482519 A unique strategy for mRNA cap methylation used by vesicular stomatitis virus Jianrong Li, Jennifer T. Wang, and Sean P. J. Whelan PMCID: PMC1482520 Inhibition of dsRNA-induced signaling in hepatitis C virus-infected cells by NS3 protease-dependent and -independent mechanisms Guofeng Cheng, Jin Zhong, and Francis V. Chisari PMCID: PMC1482521 Attachment of capsular polysaccharide to the cell wall of Streptococcus pneumoniae type 2 is required for invasive disease Judy K. Morona, Renato Morona, and James C. Paton PMCID: PMC1482522 The nonredundant roles of two 4′-phosphopantetheinyl transferases in vital processes of Mycobacteria Christian Chalut, Laure Botella, Célia de Sousa-D’Auria, Christine Houssin, and Christophe Guilhot PMCID: PMC1570105 Neuroscience Structural and functional recovery from early monocular deprivation in adult rats Tommaso Pizzorusso, Paolo Medini, Silvia Landi, Sara Baldini, Nicoletta Berardi, and Lamberto Maffei PMCID: PMC1482523 Suppression of methamphetamine-seeking behavior by nicotinic agonists Takato Hiranita, Yoko Nawata, Katsuya Sakimura, Kusnandar Anggadiredja, and Tsuneyuki Yamamoto PMCID: PMC1482524 Postsynaptic inositol 1,4,5-trisphosphate signaling maintains presynaptic function of parallel fiber–Purkinje cell synapses via BDNF Kazuharu Furutani, Yohei Okubo, Sho Kakizawa, and Masamitsu Iino PMCID: PMC1482525 Microtubule affinity-regulating kinase 2 functions downstream of the PAR-3/PAR-6/atypical PKC complex in regulating hippocampal neuronal polarity Y. M. Chen, Q. J. Wang, H. S. Hu, P. C. Yu, J. Zhu, G. Drewes, H. Piwnica-Worms, and Z. G. Luo PMCID: PMC1482526 Pharmacology From the Cover:
Low-dose alcohol actions on α4β3δ GABAA receptors are reversed by the behavioral alcohol antagonist Ro15-4513 M. Wallner, H. J. Hanchar, and R. W. Olsen PMCID: PMC1482527 From the Cover:
Ethanol potently and competitively inhibits binding of the alcohol antagonist Ro15-4513 to α4/6β3δ GABAA receptors H. Jacob Hanchar, Panida Chutsrinopkun, Pratap Meera, Porntip Supavilai, Werner Sieghart, Martin Wallner, and Richard W. Olsen PMCID: PMC1482528 Physiology Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis Jianqiang Mao, Francesco J. DeMayo, Huiguang Li, Lutfi Abu-Elheiga, Ziwei Gu, Tattym E. Shaikenov, Parichher Kordari, Subrahmanyam S. Chirala, William C. Heird, and Salih J. Wakil PMCID: PMC1570106 WNK1 kinase isoform switch regulates renal potassium excretion James B. Wade, Liang Fang, Jie Liu, Dimin Li, Chao-Ling Yang, Arohan R. Subramanya, Djikolngar Maouyo, Amanda Mason, David H. Ellison, and Paul A. Welling PMCID: PMC1482529 Plant Biology Circadian rhythms in gene transcription imparted by chromosome compaction in the cyanobacterium Synechococcus elongatus Rachelle M. Smith and Stanly B. Williams PMCID: PMC1482530 Corrections Correction for Kang et al., Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway PMCID: PMC1482531 Corrects: Yibin Kang, et al. Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway. Proc Natl Acad Sci U S A. 2005 September 27; 102(39): 13909–13914. Correction for Mukherjee et al., Picosecond dynamics of a membrane protein revealed by 2D IR Prabuddha Mukherjee, Itamar Kass, Isaiah T. Arkin, and Martin T. Zanni PMCID: PMC1482532 Corrects: Prabuddha Mukherjee, et al. Picosecond dynamics of a membrane protein revealed by 2D IR. Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3528–3533. |
