| | This journal provides immediate access to some articles. Commentaries Stone age bedding by the Sea of Galilee Frank Hole PMCID: PMC409895 Modifier screens in the mouse: Time to move forward with reverse genetics David J. Curtis PMCID: PMC409896 Transgenic pigs expressing plant genes Heiner Niemann PMCID: PMC409897 Biography INAUGURAL ARTICLE by a Recently Elected Academy Member: Biography of Mark A. Ratner Emma Hitt PMCID: PMC409946 Physical Sciences Chemistry INAUGURAL ARTICLE by a Recently Elected Academy Member: Application of evolutionary algorithm methods to polypeptide folding: Comparison with experimental results for unsolvated Ac-(Ala-Gly-Gly) 5-LysH +Martin Damsbo, Brian S. Kinnear, Matthew R. Hartings, Peder T. Ruhoff, Martin F. Jarrold, and Mark A. Ratner PMCID: PMC409899 Response experiments for nonlinear systems with application to reaction kinetics and genetics Marcel O. Vlad, Adam Arkin, and John Ross PMCID: PMC409900 From the Cover:
Hydration and mobility of HO-(aq) D. Asthagiri, Lawrence R. Pratt, J. D. Kress, and Maria A. Gomez PMCID: PMC409901 Physics Fluid-dynamical basis of the embryonic development of left-right asymmetry in vertebrates Julyan H. E. Cartwright, Oreste Piro, and Idan Tuval PMCID: PMC409902 Statistics A random-periods model for expression of cell-cycle genes Delong Liu, David M. Umbach, Shyamal D. Peddada, Leping Li, Patrick W. Crockett, and Clarice R. Weinberg PMCID: PMC409903 Biological Sciences Biochemistry Identification of core amino acids stabilizing rhodopsin A. J. Rader, Gülsüm Anderson, Basak Isin, H. Gobind Khorana, Ivet Bahar, and Judith Klein-Seetharaman PMCID: PMC409904 Functional evidence for active site location of tetrameric thymidylate synthase X at the interphase of three monomers Damien Leduc, Sébastien Graziani, Gerard Lipowski, Christophe Marchand, Pierre Le Maréchal, Ursula Liebl, and Hannu Myllykallio PMCID: PMC409905 Short amino acid stretches can mediate amyloid formation in globular proteins: The Src homology 3 (SH3) case Salvador Ventura, Jesús Zurdo, Saravanakumar Narayanan, Matilde Parreño, Ramón Mangues, Bernd Reif, Fabrizio Chiti, Elisa Giannoni, Christopher M. Dobson, Francesc X. Aviles, and Luis Serrano PMCID: PMC409906 The DNA-unwinding mechanism of the ring helicase of bacteriophage T7 Yong-Joo Jeong, Mikhail K. Levin, and Smita S. Patel PMCID: PMC409907 CD81 is an entry coreceptor for hepatitis C virus Emmanuel G. Cormier, Fay Tsamis, Francis Kajumo, Robert J. Durso, Jason P. Gardner, and Tatjana Dragic PMCID: PMC409908 Malondialdehyde adducts in DNA arrest transcription by T7 RNA polymerase and mammalian RNA polymerase II Susan D. Cline, James N. Riggins, Silvia Tornaletti, Lawrence J. Marnett, and Philip C. Hanawalt PMCID: PMC409909 From the Cover:
Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis Katsumi Iizuka, Richard K. Bruick, Guosheng Liang, Jay D. Horton, and Kosaku Uyeda PMCID: PMC409910 Incorporating chemical modification constraints into a dynamic programming algorithm for prediction of RNA secondary structure David H. Mathews, Matthew D. Disney, Jessica L. Childs, Susan J. Schroeder, Michael Zuker, and Douglas H. Turner PMCID: PMC409911 Biophysics INAUGURAL ARTICLE by a Recently Elected Academy Member: Application of evolutionary algorithm methods to polypeptide folding: Comparison with experimental results for unsolvated Ac-(Ala-Gly-Gly) 5-LysH +Martin Damsbo, Brian S. Kinnear, Matthew R. Hartings, Peder T. Ruhoff, Martin F. Jarrold, and Mark A. Ratner PMCID: PMC409899 The C-terminal domain of DNA gyrase A adopts a DNA-bending β-pinwheel fold Kevin D. Corbett, Ryan K. Shultzaberger, and James M. Berger PMCID: PMC409912 The unfolding kinetics of ubiquitin captured with single-molecule force-clamp techniques Michael Schlierf, Hongbin Li, and Julio M. Fernandez PMCID: PMC409913 Measuring the refolding of β-sheets with different turn sequences on a nanosecond time scale Rita P.-Y. Chen, Joseph J.-T. Huang, Hsin-Liang Chen, Howard Jan, Marappan Velusamy, Chung-Tien Lee, Wunshain Fann, Randy W. Larsen, and Sunney I. Chan PMCID: PMC409914 Cell Biology A random-periods model for expression of cell-cycle genes Delong Liu, David M. Umbach, Shyamal D. Peddada, Leping Li, Patrick W. Crockett, and Clarice R. Weinberg PMCID: PMC409903 Imaging single membrane fusion events mediated by SNARE proteins Marina Fix, Thomas J. Melia, Jyoti K. Jaiswal, Joshua Z. Rappoport, Daoqi You, Thomas H. Söllner, James E. Rothman, and Sanford M. Simon PMCID: PMC409915 Single-molecule imaging analysis of Ras activation in living cells Hideji Murakoshi, Ryota Iino, Takeshi Kobayashi, Takahiro Fujiwara, Chika Ohshima, Akihiko Yoshimura, and Akihiro Kusumi PMCID: PMC409916 Developmental Biology Fluid-dynamical basis of the embryonic development of left-right asymmetry in vertebrates Julyan H. E. Cartwright, Oreste Piro, and Idan Tuval PMCID: PMC409902 Paracrine regulation of mammalian oocyte maturation and male germ cell survival Kazuhiro Kawamura, Jin Kumagai, Satoko Sudo, Sang-Young Chun, Margareta Pisarska, Hiroki Morita, Jorma Toppari, Ping Fu, John D. Wade, Ross A. D. Bathgate, and Aaron J. W. Hsueh PMCID: PMC409917 Genetics The diploid genome sequence of Candida albicans Ted Jones, Nancy A. Federspiel, Hiroji Chibana, Jan Dungan, Sue Kalman, B. B. Magee, George Newport, Yvonne R. Thorstenson, Nina Agabian, P. T. Magee, Ronald W. Davis, and Stewart Scherer PMCID: PMC409918 Production of α-1,3-galactosyltransferase null pigs by means of nuclear transfer with fibroblasts bearing loss of heterozygosity mutations Donna Kolber-Simonds, Liangxue Lai, Steven R. Watt, Maria Denaro, Scott Arn, Monica L. Augenstein, Jeffery Betthauser, David B. Carter, Julia L. Greenstein, Yanhong Hao, Gi-Sun Im, Zhonghua Liu, Greg D. Mell, Clifton N. Murphy, Kwang-Wook Park, August Rieke, David J. J. Ryan, David H. Sachs, Erik J. Forsberg, Randall S. Prather, and Robert J. Hawley PMCID: PMC409919 Imprinting of the human L3MBTL gene, a polycomb family member located in a region of chromosome 20 deleted in human myeloid malignancies Juan Li, Anthony J. Bench, George S. Vassiliou, Nasios Fourouclas, Anne C. Ferguson-Smith, and Anthony R. Green PMCID: PMC409920 From the Cover:
CRE recombinase-inducible RNA interference mediated by lentiviral vectors Gustavo Tiscornia, Vinay Tergaonkar, Francesco Galimi, and Inder M. Verma PMCID: PMC409921 Genome-wide somatic hypermutation Clifford L. Wang, Ryan A. Harper, and Matthias Wabl PMCID: PMC409922 Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome Gangning Liang, Joy C. Y. Lin, Vivian Wei, Christine Yoo, Jonathan C. Cheng, Carvell T. Nguyen, Daniel J. Weisenberger, Gerda Egger, Daiya Takai, Felicidad A. Gonzales, and Peter A. Jones PMCID: PMC409923 Immunology Multidimensional signatures in antimicrobial peptides Nannette Y. Yount and Michael R. Yeaman PMCID: PMC409924 In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish David M. Langenau, Adolfo A. Ferrando, David Traver, Jeffery L. Kutok, John-Paul D. Hezel, John P. Kanki, Leonard I. Zon, A. Thomas Look, and Nikolaus S. Trede PMCID: PMC409925 RNA surveillance down-regulates expression of nonfunctional κ alleles and detects premature termination within the last κ exon Laurent Delpy, Christophe Sirac, Emmanuelle Magnoux, Sophie Duchez, and Michel Cogné PMCID: PMC409926 Medical Sciences Translocation and cleavage of myocardial dystrophin as a common pathway to advanced heart failure: A scheme for the progression of cardiac dysfunction Teruhiko Toyo-Oka, Tomie Kawada, Jumi Nakata, Han Xie, Masashi Urabe, Fujiko Masui, Takashi Ebisawa, Asaki Tezuka, Kuniaki Iwasawa, Toshiaki Nakajima, Yoshio Uehara, Hiroyuki Kumagai, Sawa Kostin, Jutta Schaper, Mikio Nakazawa, and Keiya Ozawa PMCID: PMC409927 p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels N. Gopalakrishna Iyer, Suet-Feung Chin, Hilal Ozdag, Yataro Daigo, De-En Hu, Massimiliano Cariati, Kevin Brindle, Samuel Aparicio, and Carlos Caldas PMCID: PMC409928 Ribozyme knockdown functionally links a 1,25(OH)2D3 membrane binding protein (1,25D3-MARRS) and phosphate uptake in intestinal cells I. Nemere, M. C. Farach-Carson, B. Rohe, T. M. Sterling, A. W. Norman, B. D. Boyan, and S. E. Safford PMCID: PMC409929 Chromatin immunoprecipitation microarrays for identification of genes silenced by histone H3 lysine 9 methylation Yutaka Kondo, Lanlan Shen, Pearlly S. Yan, Tim Hui-Ming Huang, and Jean-Pierre J. Issa PMCID: PMC409930 Developmentally regulated IκB expression in intestinal epithelium and susceptibility to flagellin-induced inflammation Erika C. Claud, Lei Lu, Pauline M. Anton, Tor Savidge, W. Allan Walker, and Bobby J. Cherayil PMCID: PMC409931 Microbiology Helicobacter pylori interacts with the human single-domain trefoil protein TFF1 Marguerite Clyne, Paul Dillon, Stephen Daly, Richard O'Kennedy, Felicity E. B. May, Bruce R. Westley, and Brendan Drumm PMCID: PMC409932 Recruitment of a cytoplasmic response regulator to the cell pole is linked to its cell cycle-regulated proteolysis Kathleen R. Ryan, Sarah Huntwork, and Lucy Shapiro PMCID: PMC409933 From the Cover:
Identification of hepoxilin A3 in inflammatory events: A required role in neutrophil migration across intestinal epithelia Randall J. Mrsny, Andrew T. Gewirtz, Dario Siccardi, Tor Savidge, Bryan P. Hurley, James L. Madara, and Beth A. McCormick PMCID: PMC409934 Carbon nutrition of Escherichia coli in the mouse intestine Dong-Eun Chang, Darren J. Smalley, Don L. Tucker, Mary P. Leatham, Wendy E. Norris, Sarah J. Stevenson, April B. Anderson, Joe E. Grissom, David C. Laux, Paul S. Cohen, and Tyrrell Conway PMCID: PMC409935 A small-molecule approach to studying invasive mechanisms of Toxoplasma gondii Kimberly L. Carey, Nicholas J. Westwood, Timothy J. Mitchison, and Gary E. Ward PMCID: PMC409936 Interactions of glutaredoxins, ribonucleotide reductase, and components of the DNA replication system of Escherichia coli Ron Ortenberg, Stéphanie Gon, Amir Porat, and Jon Beckwith PMCID: PMC409937 The soluble ectodomain of herpes simplex virus gD contains a membrane-proximal pro-fusion domain and suffices to mediate virus entry Francesca Cocchi, Daniela Fusco, Laura Menotti, Tatiana Gianni, Roselyn J. Eisenberg, Gary H. Cohen, and Gabriella Campadelli-Fiume PMCID: PMC409938 From the Cover:
Chlamydial histone-DNA interactions are disrupted by a metabolite in the methylerythritol phosphate pathway of isoprenoid biosynthesis Nicole A. Grieshaber, Elizabeth R. Fischer, David J. Mead, Cheryl A. Dooley, and Ted Hackstadt PMCID: PMC409939 Neuroscience A parieto-frontal network for visual numerical information in the monkey Andreas Nieder and Earl K. Miller PMCID: PMC409940 Parallel somatic and synaptic processing in the induction of intermediate-term and long-term synaptic facilitation in Aplysia Carolyn M. Sherff and Thomas J. Carew PMCID: PMC409941 Physiology Urinary concentrating defect in mice with selective deletion of phloretin-sensitive urea transporters in the renal collecting duct Robert A. Fenton, Chung-Lin Chou, Gavin S. Stewart, Craig P. Smith, and Mark A. Knepper PMCID: PMC409942 Plant Biology New thioredoxin targets in the unicellular photosynthetic eukaryote Chlamydomonas reinhardtii Stéphane D. Lemaire, Blanche Guillon, Pierre Le Maréchal, Eliane Keryer, Myroslawa Miginiac-Maslow, and Paulette Decottignies PMCID: PMC409943 An invariant aspartic acid in the DNA glycosylase domain of DEMETER is necessary for transcriptional activation of the imprinted MEDEA gene Yeonhee Choi, John J. Harada, Robert B. Goldberg, and Robert L. Fischer PMCID: PMC409944 Psychology Impaired spontaneous anthropomorphizing despite intact perception and social knowledge Andrea S. Heberlein and Ralph Adolphs PMCID: PMC409945 |
