| | This journal provides immediate access to some articles. In This Issue Proc Natl Acad Sci U S A. 2005 November 22; 102(47): 16907–16908. doi: 10.1073/iti4705102.PMCID: PMC1288024 Commentaries Target site localization by site-specific, DNA-binding proteins Jonathan Widom PMCID: PMC1288015 Better than platinum? Fuel cells energized by enzymes Jesse W. Tye, Michael B. Hall, and Marcetta Y. Darensbourg PMCID: PMC1288019 Profiles Profile of William S. Knowles Oliver Yun PMCID: PMC1287994 Profile of Nancy A. Moran Nick Zagorski PMCID: PMC1288003 Physical Sciences Applied Physical Sciences Diffusion-limited phase separation in eukaryotic chemotaxis Andrea Gamba, Antonio de Candia, Stefano Di Talia, Antonio Coniglio, Federico Bussolino, and Guido Serini PMCID: PMC1287969 An interpretation of size-scale plasticity in geometrically confined systems H. D. Espinosa, S. Berbenni, M. Panico, and K. W. Schwarz PMCID: PMC1288008 Statistics Bayesian coclustering of Anopheles gene expression time series: Study of immune defense response to multiple experimental challenges Nicholas A. Heard, Christopher C. Holmes, David A. Stephens, David J. Hand, and George Dimopoulos PMCID: PMC1287961 Reliable prediction of transcription factor binding sites by phylogenetic verification Xiaoman Li, Sheng Zhong, and Wing H. Wong PMCID: PMC1283155 Biological Sciences Applied Biological Sciences From the Cover:
Electrocatalytic hydrogen oxidation by an enzyme at high carbon monoxide or oxygen levels Kylie A. Vincent, James A. Cracknell, Oliver Lenz, Ingo Zebger, Bärbel Friedrich, and Fraser A. Armstrong PMCID: PMC1287975 Biochemistry Identification of an Escherichia coli O157:H7 heme oxygenase with tandem functional repeats Michael D. L. Suits, Gour P. Pal, Kanji Nakatsu, Allan Matte, Miroslaw Cygler, and Zongchao Jia PMCID: PMC1287972 MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function David T. Humphreys, Belinda J. Westman, David I. K. Martin, and Thomas Preiss PMCID: PMC1287990 Regulation of endothelial nitric oxide synthase by small RNA Ming-Xiang Zhang, Hesheng Ou, Ying H. Shen, Jing Wang, Jian Wang, Joseph Coselli, and Xing Li Wang PMCID: PMC1287968 SUMO modification negatively modulates the transcriptional activity of CREB-binding protein via the recruitment of Daxx Hong-Yi Kuo, Che-Chang Chang, Jen-Chong Jeng, Hui-Mei Hu, Ding-Yen Lin, Gerd G. Maul, Roland P. S. Kwok, and Hsiu-Ming Shih PMCID: PMC1287974 Biophysics Reliable prediction of transcription factor binding sites by phylogenetic verification Xiaoman Li, Sheng Zhong, and Wing H. Wong PMCID: PMC1283155 Study of single-nucleotide polymorphisms by means of electrical conductance measurements Joshua Hihath, Bingqian Xu, Peiming Zhang, and Nongjian Tao PMCID: PMC1287980 Correlated dynamics of consecutive residues reveal transient and cooperative unfolding of secondary structure in proteins Patrik Lundström, Frans A. A. Mulder, and Mikael Akke PMCID: PMC1287973 Single-myosin crossbridge interactions with actin filaments regulated by troponin-tropomyosin Neil M. Kad, Scott Kim, David M. Warshaw, Peter VanBuren, and Josh E. Baker PMCID: PMC1287988 Adaptive shift in the domain of negative stiffness during spontaneous oscillation by hair bundles from the internal ear Loïc Le Goff, Dolores Bozovic, and A. J. Hudspeth PMCID: PMC1288017 A structural model for unfolded proteins from residual dipolar couplings and small-angle x-ray scattering Pau Bernadó, Laurence Blanchard, Peter Timmins, Dominique Marion, Rob W. H. Ruigrok, and Martin Blackledge PMCID: PMC1287987 Cell Biology Mechanism of mRNA transport in the nucleus Diana Y. Vargas, Arjun Raj, Salvatore A. E. Marras, Fred Russell Kramer, and Sanjay Tyagi PMCID: PMC1287982 Requirement for chitin biosynthesis in epithelial tube morphogenesis W. Patrick Devine, Barry Lubarsky, Ken Shaw, Stefan Luschnig, Lisa Messina, and Mark A. Krasnow PMCID: PMC1283532 Transthyretin constitutes a functional component in pancreatic β-cell stimulus-secretion coupling Essam Refai, Nancy Dekki, Shao-Nian Yang, Gabriela Imreh, Over Cabrera, Lina Yu, Guang Yang, Svante Norgren, Sophia M. Rössner, Luca Inverardi, Camillo Ricordi, Gunilla Olivecrona, Mats Andersson, Hans Jörnvall, Per-Olof Berggren, and Lisa Juntti-Berggren PMCID: PMC1287967 Developmental Biology Molecular mechanisms of Sonic hedgehog mutant effects in holoprosencephaly Tapan Maity, Naoyuki Fuse, and Philip A. Beachy PMCID: PMC1282174 Ecology From the Cover:
The role of opportunity in the unintentional introduction of nonnative ants Andrew V. Suarez, David A. Holway, and Philip S. Ward PMCID: PMC1287985 Environmental Sciences Temperature-driven decoupling of key phases of organic matter degradation in marine sediments Nathaniel B. Weston and Samantha B. Joye PMCID: PMC1283156 Decreased levels of CXC-chemokines in serum of benzene-exposed workers identified by array-based proteomics Roel Vermeulen, Qing Lan, Luoping Zhang, Laura Gunn, Diane McCarthy, Ronald L. Woodbury, Marielena McGuire, Vladimir N. Podust, Guilan Li, Nilanjan Chatterjee, Ruidong Mu, Songnian Yin, Nathaniel Rothman, and Martyn T. Smith PMCID: PMC1288009 Evolution INAUGURAL ARTICLE by a Recently Elected Academy Member: The players in a mutualistic symbiosis: Insects, bacteria, viruses, and virulence genes Nancy A. Moran, Patrick H. Degnan, Scott R. Santos, Helen E. Dunbar, and Howard Ochman PMCID: PMC1287993 Evolutionary regulation of the blind subterranean mole rat, Spalax, revealed by genome-wide gene expression L. I. Brodsky, J. Jacob-Hirsch, A. Avivi, L. Trakhtenbrot, S. Zeligson, N. Amariglio, A. Paz, A. B. Korol, M. Band, G. Rechavi, and E. Nevo PMCID: PMC1287979 Genetics From the Cover:
DCDC2 is associated with reading disability and modulates neuronal development in the brain Haiying Meng, Shelley D. Smith, Karl Hager, Matthew Held, Jonathan Liu, Richard K. Olson, Bruce F. Pennington, John C. DeFries, Joel Gelernter, Thomas O'Reilly-Pol, Stefan Somlo, Pawel Skudlarski, Sally E. Shaywitz, Bennett A. Shaywitz, Karen Marchione, Yu Wang, Murugan Paramasivam, Joseph J. LoTurco, Grier P. Page, and Jeffrey R. Gruen PMCID: PMC1278934 Somatic integration of an oncogene-harboring Sleeping Beauty transposon models liver tumor development in the mouse Corey M. Carlson, Joel L. Frandsen, Nicole Kirchhof, R. Scott McIvor, and David A. Largaespada PMCID: PMC1287966 Chromatin domain activation via GATA-1 utilization of a small subset of dispersed GATA motifs within a broad chromosomal region Hogune Im, Jeffrey A. Grass, Kirby D. Johnson, Shin-Il Kim, Meghan E. Boyer, Anthony N. Imbalzano, James J. Bieker, and Emery H. Bresnick PMCID: PMC1287986 Immunology Hypoxia inducible factor 1α regulates T cell receptor signal transduction Aaron K. Neumann, Jaeseok Yang, Mangat P. Biju, Suresh K. Joseph, Randall S. Johnson, Volker H. Haase, Bruce D. Freedman, and Laurence A. Turka PMCID: PMC1287984 Toll-like receptor 3 ligand attenuates LPS-induced liver injury by down-regulation of toll-like receptor 4 expression on macrophages Wei Jiang, Rui Sun, Haiming Wei, and Zhigang Tian PMCID: PMC1287976 Activation-induced deaminase cloning, localization, and protein extraction from young VH-mutant rabbit appendix Guibin Yang, Harold Obiakor, Rajesh K. Sinha, Barbara A. Newman, Brian L. Hood, Thomas P. Conrads, Timothy D. Veenstra, and Rose G. Mage PMCID: PMC1282565 Suppressor of cytokine signaling-1 selectively inhibits LPS-induced IL-6 production by regulating JAK–STAT Akihiro Kimura, Tetsuji Naka, Tatsushi Muta, Osamu Takeuchi, Shizuo Akira, Ichiro Kawase, and Tadamitsu Kishimoto PMCID: PMC1288004 Histone hyperacetylated domains across the Ifng gene region in natural killer cells and T cells Shaojing Chang and Thomas M. Aune PMCID: PMC1283154 T-bet-dependent expression of osteopontin contributes to T cell polarization Mari L. Shinohara, Marianne Jansson, Eun Sook Hwang, Miriam B. F. Werneck, Laurie H. Glimcher, and Harvey Cantor PMCID: PMC1288014 The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a “molecular ruler” mechanism Shih-Chung Chang, Frank Momburg, Nidhi Bhutani, and Alfred L. Goldberg PMCID: PMC1287962 T cell Ig and mucin 1 (TIM-1) is expressed on in vivo-activated T cells and provides a costimulatory signal for T cell activation Anjali J. de Souza, Timothy B. Oriss, Katherine J. O'Malley, Anuradha Ray, and Lawrence P. Kane PMCID: PMC1288013 Medical Sciences The effect of TERC haploinsufficiency on the inheritance of telomere length Fred Goldman, Rachida Bouarich, Shashikant Kulkarni, Sara Freeman, Hong-Yan Du, Lea Harrington, Philip J. Mason, Arturo Londoño-Vallejo, and Monica Bessler PMCID: PMC1287981 The asialoglycoprotein receptor clears glycoconjugates terminating with sialic acidα2,6GalNAc Eric I. Park, Yiling Mi, Carlo Unverzagt, Hans-Joachim Gabius, and Jacques U. Baenziger PMCID: PMC1288006 Calcineurin regulates bone formation by the osteoblast Li Sun, Harry C. Blair, Yuanzhen Peng, Neeha Zaidi, Olugbenga A. Adebanjo, Xue Bin Wu, Xing Yao Wu, Jameel Iqbal, Solomon Epstein, Etsuko Abe, Baljit S. Moonga, and Mone Zaidi PMCID: PMC1288002 Microbiology Three small RNAs jointly ensure secondary metabolism and biocontrol in Pseudomonas fluorescens CHA0 Elisabeth Kay, Christophe Dubuis, and Dieter Haas PMCID: PMC1287983 From the Cover:
Human C4b-binding protein selectively interacts with Neisseria gonorrhoeae and results in species-specific infection Jutamas Ngampasutadol, Sanjay Ram, Anna M. Blom, Hanna Jarva, Ann E. Jerse, Egil Lien, Jon Goguen, Sunita Gulati, and Peter A. Rice PMCID: PMC1287989 Parvoviral virions deploy a capsid-tethered lipolytic enzyme to breach the endosomal membrane during cell entry Glen A. Farr, Li-guo Zhang, and Peter Tattersall PMCID: PMC1288001 Neuroscience A schizophrenia-related sensorimotor deficit links α3-containing GABAA receptors to a dopamine hyperfunction B. K. Yee, R. Keist, L. von Boehmer, R. Studer, D. Benke, N. Hagenbuch, Y. Dong, R. C. Malenka, J.-M. Fritschy, H. Bluethmann, J. Feldon, H. Möhler, and U. Rudolph PMCID: PMC1288020 Purkinje cell long-term depression is prevented by T-588, a neuroprotective compound that reduces cytosolic calcium release from intracellular stores Tatsuo Kimura, Mutsuyuki Sugimori, and Rodolfo R. Llinás PMCID: PMC1287999 Normal motor learning during pharmacological prevention of Purkinje cell long-term depression John P. Welsh, Hidetoshi Yamaguchi, Xiao-Hui Zeng, Masanobu Kojo, Yasushi Nakada, Akiko Takagi, Mutsuyuki Sugimori, and Rodolfo R. Llinás PMCID: PMC1288000 Pyramidal neurons of upper cortical layers generated by NEX-positive progenitor cells in the subventricular zone Sheng-Xi Wu, Sandra Goebbels, Kouichi Nakamura, Kazuhiro Nakamura, Kouhei Kometani, Nagahiro Minato, Takeshi Kaneko, Klaus-Armin Nave, and Nobuaki Tamamaki PMCID: PMC1288007 Visibility, visual awareness, and visual masking of simple unattended targets are confined to areas in the occipital cortex beyond human V1/V2 Peter U. Tse, Susana Martinez-Conde, Alexander A. Schlegel, and Stephen L. Macknik PMCID: PMC1282175 Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex Bin Chen, Laura R. Schaevitz, and Susan K. McConnell PMCID: PMC1282569 Hzf protein regulates dendritic localization and BDNF-induced translation of type 1 inositol 1,4,5-trisphosphate receptor mRNA Takatoshi Iijima, Takao Imai, Yuki Kimura, Alan Bernstein, Hirotaka James Okano, Michisuke Yuzaki, and Hideyuki Okano PMCID: PMC1287977 The stress-regulated protein M6a is a key modulator for neurite outgrowth and filopodium/spine formation Julieta Alfonso, María E. Fernández, Benjamin Cooper, Gabriele Flugge, and Alberto C. Frasch PMCID: PMC1287971 Pharmacology Beneficial effects of concurrent autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the mouse hindlimb Claudio Napoli, Sharon Williams-Ignarro, Filomena de Nigris, Gaetano de Rosa, Lilach O. Lerman, Bartolomeo Farzati, Angelo Matarazzo, Giacomo Sica, Chiara Botti, Andrea Fiore, Russell E. Byrns, Daigo Sumi, Vincenzo Sica, and Louis J. Ignarro PMCID: PMC1288005 Nitric oxide-donating aspirin induces apoptosis in human colon cancer cells through induction of oxidative stress Jianjun Gao, Xiaoping Liu, and Basil Rigas PMCID: PMC1287992 Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer β-amyloid peptide in rodent Nigel H. Greig, Tadanobu Utsuki, Donald K. Ingram, Yue Wang, Giancarlo Pepeu, Carla Scali, Qian-Sheng Yu, Jacek Mamczarz, Harold W. Holloway, Tony Giordano, DeMao Chen, Katsutoshi Furukawa, Kumar Sambamurti, Arnold Brossi, and Debomoy K. Lahiri PMCID: PMC1288010 Physiology The β1a subunit is essential for the assembly of dihydropyridine-receptor arrays in skeletal muscle Johann Schredelseker, Valentina Di Biase, Gerald J. Obermair, E. Tatiana Felder, Bernhard E. Flucher, Clara Franzini-Armstrong, and Manfred Grabner PMCID: PMC1288016 Plant Biology Phylogenetic engineering at an interface between large and small subunits imparts land-plant kinetic properties to algal Rubisco Robert J. Spreitzer, Srinivasa R. Peddi, and Sriram Satagopan PMCID: PMC1287997 CHR11, a chromatin-remodeling factor essential for nuclear proliferation during female gametogenesis in Arabidopsis thaliana Wilson Huanca-Mamani, Marcelina Garcia-Aguilar, Gloria León-Martínez, Ueli Grossniklaus, and Jean-Philippe Vielle-Calzada PMCID: PMC1287998 Psychology From the Cover:
Early experience in humans is associated with changes in neuropeptides critical for regulating social behavior Alison B. Wismer Fries, Toni E. Ziegler, Joseph R. Kurian, Steve Jacoris, and Seth D. Pollak PMCID: PMC1287978 Social Sciences Anthropology Preceramic irrigation canals in the Peruvian Andes Tom D. Dillehay, Herbert H. Eling, Jr., and Jack Rossen PMCID: PMC1288011 Psychology Newborns' preference for face-relevant stimuli: Effects of contrast polarity Teresa Farroni, Mark H. Johnson, Enrica Menon, Luisa Zulian, Dino Faraguna, and Gergely Csibra PMCID: PMC1287965 Corrections Proc Natl Acad Sci U S A. 2005 November 22; 102(47): 17251. Published online 2005 November 10. doi: 10.1073/pnas.0509008102.PMCID: PMC1288022 Corrects: Xiao Hu, et al. Promoters of the murine embryonic β-like globin genes Ey and βh1 do not compete for interaction with the β-globin locus control region. Proc Natl Acad Sci U S A. 2003 February 4; 100(3): 1111–1115. Proc Natl Acad Sci U S A. 2005 November 22; 102(47): 17251. Published online 2005 November 10. doi: 10.1073/pnas.0509017102.PMCID: PMC1288023 Corrects: N. Devidze, et al. Sex and estrogenic effects on coexpression of mRNAs in single ventromedial hypothalamic neurons. Proc Natl Acad Sci U S A. 2005 October 4; 102(40): 14446–14451. |
