| | This journal provides immediate access to some articles. In This Issue Proc Natl Acad Sci U S A. 2005 November 15; 102(46): 16531–16532. doi: 10.1073/iti4605102.PMCID: PMC1283861 Commentaries Reproductive fitness and tooth wear: Milking as much as possible out of dental topographic analysis Peter S. Ungar PMCID: PMC1283857 Leucine-rich repeat kinase 2: A new player with a familiar theme for Parkinson's disease pathogenesis Chenjian Li and M. Flint Beal PMCID: PMC1283846 Perspective The transduction of the nitrogen regulation signal in Saccharomyces cerevisiae Boris Magasanik PMCID: PMC1283824 Profile Profile of Jeffrey C. Hall Regina Nuzzo PMCID: PMC1283854 Physical Sciences Applied Physical Sciences Relation between the Widom line and the dynamic crossover in systems with a liquid–liquid phase transition Limei Xu, Pradeep Kumar, S. V. Buldyrev, S.-H. Chen, P. H. Poole, F. Sciortino, and H. E. Stanley PMCID: PMC1283834 Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy Conor L. Evans, Eric O. Potma, Mehron Puoris'haag, Daniel Côté, Charles P. Lin, and X. Sunney Xie PMCID: PMC1283840 Chemistry X-ray absorption spectroscopy of chloroperoxidase compound I: Insight into the reactive intermediate of P450 chemistry Kari L. Stone, Rachel K. Behan, and Michael T. Green PMCID: PMC1283822 Protein folding by distributed computing and the denatured state ensemble Neelan J. Marianayagam, Nicolas L. Fawzi, and Teresa Head-Gordon PMCID: PMC1283817 Mathematics An embedded genus-one helicoid Matthias Weber, David Hoffman, and Michael Wolf PMCID: PMC1283835 Physics An index to quantify an individual's scientific research output J. E. Hirsch PMCID: PMC1283832 Biological Sciences Agricultural Sciences Targeted down-regulation of cytochrome P450 enzymes for forage quality improvement in alfalfa (Medicago sativa L.) M. S. Srinivasa Reddy, Fang Chen, Gail Shadle, Lisa Jackson, Hugh Aljoe, and Richard A. Dixon PMCID: PMC1283808 Anthropology From the Cover:
Dental senescence in a long-lived primate links infant survival to rainfall Stephen J. King, Summer J. Arrigo-Nelson, Sharon T. Pochron, Gina M. Semprebon, Laurie R. Godfrey, Patricia C. Wright, and Jukka Jernvall PMCID: PMC1283847 Biochemistry Resistance to inhibitors of cholinesterase 8A catalyzes release of Gαi-GTP and nuclear mitotic apparatus protein (NuMA) from NuMA/LGN/Gαi-GDP complexes Gregory G. Tall and Alfred G. Gilman PMCID: PMC1283842 RhlB helicase rather than enolase is the β-subunit of the Escherichia coli polynucleotide phosphorylase (PNPase)–exoribonucleolytic complex Pei-Hsun Lin and Sue Lin-Chao PMCID: PMC1277965 Control of mammalian glycogen synthase by PAS kinase Wayne A. Wilson, Alexander V. Skurat, Brandon Probst, Anna de Paoli-Roach, Peter J. Roach, and Jared Rutter PMCID: PMC1283851 Structural basis of the resistance of an insect carboxypeptidase to plant protease inhibitors Alex Bayés, Mireia Comellas-Bigler, Monica Rodríguez de la Vega, Klaus Maskos, Wolfram Bode, Francesc X. Aviles, Maarten A. Jongsma, Jules Beekwilder, and Josep Vendrell PMCID: PMC1283804 Cyclin H binding to the RARα activation function (AF)-2 domain directs phosphorylation of the AF-1 domain by cyclin-dependent kinase 7 Gaétan Bour, Emilie Gaillard, Nathalie Bruck, Sébastien Lalevée, Jean-Luc Plassat, Didier Busso, Jean-Pierre Samama, and Cécile Rochette-Egly PMCID: PMC1283805 An essential RNase III insertion editing endonuclease in Trypanosoma brucei Jason Carnes, James Raffaello Trotter, Nancy Lewis Ernst, Alodie Steinberg, and Kenneth Stuart PMCID: PMC1283813 Deleterious mutations in small subunit ribosomal RNA identify functional sites and potential targets for antibiotics Aymen Yassin, Kurt Fredrick, and Alexander S. Mankin PMCID: PMC1283848 The structural basis of myotonic dystrophy from the crystal structure of CUG repeats Blaine H. M. Mooers, Jeremy S. Logue, and J. Andrew Berglund PMCID: PMC1283809 Computational docking and solution x-ray scattering predict a membrane-interacting role for the histone domain of the Ras activator son of sevenless Holger Sondermann, Bhushan Nagar, Dafna Bar-Sagi, and John Kuriyan PMCID: PMC1276615 Biophysics INAUGURAL ARTICLE by a Recently Elected Academy Member: Making ATP Jianhua Xing, Jung-Chi Liao, and George Oster PMCID: PMC1283826 Relation between the Widom line and the dynamic crossover in systems with a liquid–liquid phase transition Limei Xu, Pradeep Kumar, S. V. Buldyrev, S.-H. Chen, P. H. Poole, F. Sciortino, and H. E. Stanley PMCID: PMC1283834 X-ray absorption spectroscopy of chloroperoxidase compound I: Insight into the reactive intermediate of P450 chemistry Kari L. Stone, Rachel K. Behan, and Michael T. Green PMCID: PMC1283822 Dynamic force spectroscopy of parallel individual Mucin1–antibody bonds Todd A. Sulchek, Raymond W. Friddle, Kevin Langry, Edmond Y. Lau, Huguette Albrecht, Timothy V. Ratto, Sally J. DeNardo, Michael E. Colvin, and Aleksandr Noy PMCID: PMC1276867 Actin-bound structures of Wiskott–Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly David Chereau, Frederic Kerff, Philip Graceffa, Zenon Grabarek, Knut Langsetmo, and Roberto Dominguez PMCID: PMC1283820 A microscopic view of miniprotein folding: Enhanced folding efficiency through formation of an intermediate Hannes Neuweiler, Sören Doose, and Markus Sauer PMCID: PMC1283828 Computational redesign of human butyrylcholinesterase for anticocaine medication Yongmei Pan, Daquan Gao, Wenchao Yang, Hoon Cho, Guangfu Yang, Hsin-Hsiung Tai, and Chang-Guo Zhan PMCID: PMC1283827 Effect of modulating unfolded state structure on the folding kinetics of the villin headpiece subdomain Scott H. Brewer, Dung M. Vu, Yuefeng Tang, Ying Li, Stefan Franzen, Daniel P. Raleigh, and R. Brian Dyer PMCID: PMC1283803 Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation Marcus D. Collins, Gerhard Hummer, Michael L. Quillin, Brian W. Matthews, and Sol M. Gruner PMCID: PMC1283839 The amyloid stretch hypothesis: Recruiting proteins toward the dark side Alexandra Esteras-Chopo, Luis Serrano, and Manuela López de la Paz PMCID: PMC1283810 Quantitative NMR spectroscopy of supramolecular complexes: Dynamic side pores in ClpP are important for product release Remco Sprangers, Anna Gribun, Peter M. Hwang, Walid A. Houry, and Lewis E. Kay PMCID: PMC1283831 Protein folding by distributed computing and the denatured state ensemble Neelan J. Marianayagam, Nicolas L. Fawzi, and Teresa Head-Gordon PMCID: PMC1283817 Cell Biology From the Cover:
Age-related changes of nuclear architecture in Caenorhabditis elegans Erin Haithcock, Yaron Dayani, Ester Neufeld, Adam J. Zahand, Naomi Feinstein, Anna Mattout, Yosef Gruenbaum, and Jun Liu PMCID: PMC1283819 Developmental Biology Androgens regulate the permeability of the blood–testis barrier Jing Meng, Robert W. Holdcraft, James E. Shima, Michael D. Griswold, and Robert E. Braun PMCID: PMC1283811 Ecology Community inertia of Quaternary small mammal assemblages in North America Brian J. McGill, Elizabeth A. Hadly, and Brian A. Maurer PMCID: PMC1283796 Pleistocene to recent dietary shifts in California condors C. P. Chamberlain, J. R. Waldbauer, K. Fox-Dobbs, S. D. Newsome, P. L. Koch, D. R. Smith, M. E. Church, S. D. Chamberlain, K. J. Sorenson, and R. Risebrough PMCID: PMC1283853 Genetics INAUGURAL ARTICLE by a Recently Elected Academy Member: Functional analysis of fruitless gene expression by transgenic manipulations of Drosophila courtship Adriana Villella, Sarah L. Ferri, Jonathan D. Krystal, and Jeffrey C. Hall PMCID: PMC1225315 Economic benefits of biodiversity exceed costs of conservation at an African rainforest reserve Robin Naidoo and Wiktor L. Adamowicz PMCID: PMC1283836 Evolution From the Cover:
Microevolution and mega-icebergs in the Antarctic L. D. Shepherd, C. D. Millar, G. Ballard, D. G. Ainley, P. R. Wilson, G. D. Haynes, C. Baroni, and D. M. Lambert PMCID: PMC1283793 Genetic diversity and reproductive success in mandrills (Mandrillus sphinx) M. Charpentier, J. M. Setchell, F. Prugnolle, L. A. Knapp, E. J. Wickings, P. Peignot, and M. Hossaert-McKey PMCID: PMC1283825 Genetics A yeast two-hybrid knockout strain to explore thioredoxin-interacting proteins in vivo Florence Vignols, Claire Bréhélin, Yolande Surdin-Kerjan, Dominique Thomas, and Yves Meyer PMCID: PMC1283818 Immunology An IL-7-dependent rebound in thymic T cell output contributes to the bone loss induced by estrogen deficiency Michaela Robbie Ryan, Rebecca Shepherd, Jennifer K. Leavey, Yuhao Gao, Francesco Grassi, Frederick J. Schnell, Wei-Ping Qian, Gilbert J. Kersh, M. Neale Weitzmann, and Roberto Pacifici PMCID: PMC1283799 Inhibition of FLT3 signaling targets DCs to ameliorate autoimmune disease Katharine A. Whartenby, Peter A. Calabresi, Erin McCadden, Bao Nguyen, David Kardian, Tianhong Wang, Claudio Mosse, Drew M. Pardoll, and Donald Small PMCID: PMC1283812 Medical Sciences The antiinflammatory effect of laminar flow: The role of PPARγ, epoxyeicosatrienoic acids, and soluble epoxide hydrolase Yi Liu, Yingjia Zhang, Kara Schmelzer, Tzong-Shyuan Lee, Xiang Fang, Yi Zhu, Arthur A. Spector, Sarjeet Gill, Christophe Morisseau, Bruce D. Hammock, and John Y.-J. Shyy PMCID: PMC1276614 Modulation of surgical fibrosis by microbial zwitterionic polysaccharides Begonia Ruiz-Perez, Doo R. Chung, Arlene H. Sharpe, Hideo Yagita, Wiltrud M. Kalka-Moll, Mohamed H. Sayegh, Dennis L. Kasper, and Arthur O. Tzianabos PMCID: PMC1283807 Evaluation of the functional diffusion map as an early biomarker of time-to-progression and overall survival in high-grade glioma Daniel A. Hamstra, Thomas L. Chenevert, Bradford A. Moffat, Timothy D. Johnson, Charles R. Meyer, Suresh K. Mukherji, Douglas J. Quint, Stephen S. Gebarski, Xiaoying Fan, Christina I. Tsien, Theodore S. Lawrence, Larry Junck, Alnawaz Rehemtulla, and Brian D. Ross PMCID: PMC1276616 Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation Akitsugu Sato, Tomohiro Kono, Kazuto Nakada, Kaori Ishikawa, Shin-Ichi Inoue, Hiromichi Yonekawa, and Jun-Ichi Hayashi PMCID: PMC1283814 Carbonic anhydrase IV and XIV knockout mice: Roles of the respective carbonic anhydrases in buffering the extracellular space in brain Gul N. Shah, Barbara Ulmasov, Abdul Waheed, Timothy Becker, Sachin Makani, Nataliya Svichar, Mitchell Chesler, and William S. Sly PMCID: PMC1283849 WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis Jesse Rinehart, Kristopher T. Kahle, Paola de los Heros, Norma Vazquez, Patricia Meade, Frederick H. Wilson, Steven C. Hebert, Ignacio Gimenez, Gerardo Gamba, and Richard P. Lifton PMCID: PMC1283841 WNK3 modulates transport of Cl- in and out of cells: Implications for control of cell volume and neuronal excitability Kristopher T. Kahle, Jesse Rinehart, Paola de los Heros, Angeliki Louvi, Patricia Meade, Norma Vazquez, Steven C. Hebert, Gerardo Gamba, Ignacio Gimenez, and Richard P. Lifton PMCID: PMC1283843 Molecular evidence for arterial repair in atherosclerosis Ravi Karra, Sreekanth Vemullapalli, Chunming Dong, Edward E. Herderick, Xiaohua Song, Kathy Slosek, Joseph R. Nevins, Mike West, Pascal J. Goldschmidt-Clermont, and David Seo PMCID: PMC1277970 Molecular basis for keratoconus: Lack of TrkA expression and its transcriptional repression by Sp3 Alessandro Lambiase, Daniela Merlo, Cristiana Mollinari, Paolo Bonini, Anna Maria Rinaldi, Mauro D' Amato, Alessandra Micera, Marco Coassin, Paolo Rama, Stefano Bonini, and Enrico Garaci PMCID: PMC1283852 Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease Masahisa Katsuno, Chen Sang, Hiroaki Adachi, Makoto Minamiyama, Masahiro Waza, Fumiaki Tanaka, Manabu Doyu, and Gen Sobue PMCID: PMC1275598 Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy Conor L. Evans, Eric O. Potma, Mehron Puoris'haag, Daniel Côté, Charles P. Lin, and X. Sunney Xie PMCID: PMC1283840 Microbiology Disruption of a Plasmodium falciparum gene linked to male sexual development causes early arrest in gametocytogenesis Tetsuya Furuya, Jianbing Mu, Karen Hayton, Anna Liu, Junhui Duan, Louis Nkrumah, Deirdre A. Joy, David A. Fidock, Hisashi Fujioka, Akhil B. Vaidya, Thomas E. Wellems, and Xin-zhuan Su PMCID: PMC1277966 Biofilm formation and phenotypic variation enhance predation-driven persistence of Vibrio cholerae Carsten Matz, Diane McDougald, Ana Maria Moreno, Pui Yi Yung, Fitnat H. Yildiz, and Staffan Kjelleberg PMCID: PMC1283802 An improved reverse genetics system for influenza A virus generation and its implications for vaccine production Gabriele Neumann, Ken Fujii, Yoichiro Kino, and Yoshihiro Kawaoka PMCID: PMC1283806 Neuroscience Structure and activity of the axon guidance protein MICAL Mythili Nadella, Mario A. Bianchet, Sandra B. Gabelli, Jennifer Barrila, and L. Mario Amzel PMCID: PMC1277968 High-resolution structure of the catalytic region of MICAL (molecule interacting with CasL), a multidomain flavoenzyme-signaling molecule Christian Siebold, Nick Berrow, Thomas S. Walter, Karl Harlos, Ray J. Owens, David I. Stuart, Jonathan R. Terman, Alex L. Kolodkin, R. Jeroen Pasterkamp, and E. Yvonne Jones PMCID: PMC1277969 From the Cover:
Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity Andrew B. West, Darren J. Moore, Saskia Biskup, Artem Bugayenko, Wanli W. Smith, Christopher A. Ross, Valina L. Dawson, and Ted M. Dawson PMCID: PMC1283829 Sustaining intrinsic growth capacity of adult neurons promotes spinal cord regeneration Simona Neumann, Kate Skinner, and Allan I. Basbaum PMCID: PMC1283855 Phosphoinositol lipids bind to phosphatidylinositol 3 (PI3)-kinase enhancer GTPase and mediate its stimulatory effect on PI3-kinase and Akt signalings Yuanxin Hu, Zhixue Liu, and Keqiang Ye PMCID: PMC1283830 RNA splicing capability of live neuronal dendrites J. Glanzer, K. Y. Miyashiro, J.-Y. Sul, L. Barrett, B. Belt, P. Haydon, and J. Eberwine PMCID: PMC1277967 Sensory suppression during feeding H. Foo and Peggy Mason PMCID: PMC1283815 Bees encode behaviorally significant spectral relationships in complex scenes to resolve stimulus ambiguity R. Beau Lotto and Martina Wicklein PMCID: PMC1283794 Unconscious processing of orientation and color without primary visual cortex Jennifer L. Boyer, Stephenie Harrison, and Tony Ro PMCID: PMC1283801 Physiology Revealing the large-scale network organization of growth hormone-secreting cells Xavier Bonnefont, Alain Lacampagne, Angela Sanchez-Hormigo, Elodie Fino, Audrey Creff, Marie-Noelle Mathieu, Sébastien Smallwood, Danielle Carmignac, Pierre Fontanaud, Pierre Travo, Gérard Alonso, Nathalie Courtois-Coutry, Steve M. Pincus, Iain C. A. F. Robinson, and Patrice Mollard PMCID: PMC1277257 Impaired involution of mammary glands in the absence of milk fat globule EGF factor 8 Rikinari Hanayama and Shigekazu Nagata PMCID: PMC1277971 Plant Biology Infection patterns in barley and wheat spikes inoculated with wild-type and trichodiene synthase gene disrupted Fusarium graminearum Carin Jansen, Diter von Wettstein, Wilhelm Schäfer, Karl-Heinz Kogel, Angelika Felk, and Frank J. Maier PMCID: PMC1283850 From the Cover:
Differential use of two cyclic electron flows around photosystem I for driving CO2-concentration mechanism in C4 photosynthesis Atsushi Takabayashi, Masahiro Kishine, Kozi Asada, Tsuyoshi Endo, and Fumihiko Sato PMCID: PMC1283823 Corrections Proc Natl Acad Sci U S A. 2005 November 15; 102(46): 16904. doi: 10.1073/pnas.0508800102.PMCID: PMC1283859 Corrects: D. Andrew Merriwether, et al. Ancient mitochondrial M haplogroups identified in the Southwest Pacific. Proc Natl Acad Sci U S A. 2005 September 13; 102(37): 13034–13039. Proc Natl Acad Sci U S A. 2005 November 15; 102(46): 16905. doi: 10.1073/pnas.0508777102.PMCID: PMC1283858 Corrects: Christophe Pichon, et al. From the Cover:
Small RNA genes expressed from Staphylococcus aureus genomic and pathogenicity islands with specific expression among pathogenic strains. Proc Natl Acad Sci U S A. 2005 October 4; 102(40): 14249–14254. Proc Natl Acad Sci U S A. 2005 November 15; 102(46): 16905. doi: 10.1073/pnas.0508805102.PMCID: PMC1283860 Corrects: Xu Song, et al. From the Cover:
Roles of PSF protein and VL30 RNA in reversible gene regulation. Proc Natl Acad Sci U S A. 2005 August 23; 102(34): 12189–12193. |
