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Volume 101(15);  April 13, 2004
Commentaries
Coincidence detection enhances appropriate wiring of the nervous system
Nicholas C. Spitzer
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5311–5312. Published online 2004 April 5. doi: 10.1073/pnas.0401270101.
PMCID: PMC397370
Silence of the genes
Oded Singer, Amiel Yanai, and Inder M. Verma
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5313–5314. Published online 2004 April 5. doi: 10.1073/pnas.0401209101.
PMCID: PMC399310
Asymmetric Catalysis Special Feature Part I
Research Articles
O-nitroso aldol synthesis: Catalytic enantioselective route to α-aminooxy carbonyl compounds via enamine intermediate
Norie Momiyama, Hiromi Torii, Susumu Saito, and Hisashi Yamamoto
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5374–5378. Published online 2004 April 5. doi: 10.1073/pnas.0307785101.
PMCID: PMC397388
Mechanistic studies of the molybdenum-catalyzed asymmetric alkylation reaction
David L. Hughes, Guy C. Lloyd-Jones, Shane W. Krska, Laure Gouriou, Veronique D. Bonnet, Kevin Jack, Yongkui Sun, David J. Mathre, and Robert A. Reamer
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5379–5384. Published online 2004 March 31. doi: 10.1073/pnas.0306918101.
PMCID: PMC397389
Asymmetric hydrogenation of α,β-unsaturated phosphonates with Rh-BisP* and Rh-MiniPHOS catalysts: Scope and mechanism of the reaction
Ilya D. Gridnev, Masaya Yasutake, Tsuneo Imamoto, and Irina P. Beletskaya
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5385–5390. Published online 2004 March 15. doi: 10.1073/pnas.0306993101.
PMCID: PMC397390
Asymmetric hetero-Diels–Alder reaction catalyzed by dirhodium(II) carboxamidates
Michael P. Doyle, Marcela Valenzuela, and Penglin Huang
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5391–5395. Published online 2004 April 1. doi: 10.1073/pnas.0307025101.
PMCID: PMC397391
An efficient, palladium-catalyzed, enantioselective synthesis of (2R)-3-butene-1,2-diol and its use in highly selective Heck reactions
Natasha Cheeseman, Martin Fox, Mark Jackson, Ian C. Lennon, and Graham Meek
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5396–5399. Published online 2004 February 11. doi: 10.1073/pnas.0307047101.
PMCID: PMC397392
OH–Pd(0) interaction as a stabilizing factor in palladium-catalyzed allylic alkylations
Kristina Hallman, Anders Frölander, Tebikie Wondimagegn, Mats Svensson, and Christina Moberg
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5400–5404. Published online 2004 April 5. doi: 10.1073/pnas.0307084101.
PMCID: PMC397393
Catalytic asymmetric addition of diorganozinc reagents to N-phosphinoylalkylimines
Alexandre Côté, Alessandro A. Boezio, and André B. Charette
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5405–5410. Published online 2004 April 2. doi: 10.1073/pnas.0307096101.
PMCID: PMC397394
New biphenol-based, fine-tunable monodentate phosphoramidite ligands for catalytic asymmetric transformations
Zihao Hua, Victor C. Vassar, Hojae Choi, and Iwao Ojima
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5411–5416. Published online 2004 March 12. doi: 10.1073/pnas.0307101101.
PMCID: PMC397395
Highly enantioselective alkyne additions to aldehydes in the presence of 1,1′-bi-2-naphthol and hexamethylphosphoramide
Ge Gao, Ru-Gang Xie, and Lin Pu
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5417–5420. Published online 2004 March 16. doi: 10.1073/pnas.0307136101.
PMCID: PMC397396
Desymmetrization of enone-diones via rhodium-catalyzed diastereo- and enantioselective tandem conjugate addition-aldol cyclization
Brian M. Bocknack, Long-Cheng Wang, and Michael J. Krische
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5421–5424. Published online 2004 March 15. doi: 10.1073/pnas.0307120101.
PMCID: PMC397397
Catalytic asymmetric addition of diphenylzinc to cyclic α,β-unsaturated ketones
Hongmei Li, Celina García, and Patrick J. Walsh
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5425–5427. Published online 2004 April 5. doi: 10.1073/pnas.0307119101.
PMCID: PMC397398
Solid-phase synthesis of chiral 3,4-diazaphospholanes and their application to catalytic asymmetric allylic alkylation
Clark R. Landis and Thomas P. Clark
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5428–5432. Published online 2004 February 25. doi: 10.1073/pnas.0307572100.
PMCID: PMC397399
Enantioselective syntheses and biological studies of aeruginosin 298-A and its analogs: Application of catalytic asymmetric phase-transfer reaction
Yuhei Fukuta, Takashi Ohshima, Vijay Gnanadesikan, Tomoyuki Shibuguchi, Tetsuhiro Nemoto, Takaya Kisugi, Tatsufumi Okino, and Masakatsu Shibasaki
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5433–5438. Published online 2004 March 2. doi: 10.1073/pnas.0307154101.
PMCID: PMC397400
Chiral phosphoramide-catalyzed, enantioselective, directed cross-aldol reactions of aldehydes
Scott E. Denmark and Tommy Bui
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5439–5444. Published online 2004 April 5. doi: 10.1073/pnas.0307212101.
PMCID: PMC397401
Mechanistic studies on the catalytic cycle of rhodium-catalyzed asymmetric 1,4-addition of aryltitanate reagents to α,β-unsaturated ketones
Norihito Tokunaga, Kazuhiro Yoshida, and Tamio Hayashi
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5445–5449. Published online 2004 February 23. doi: 10.1073/pnas.0307260101.
PMCID: PMC397402
Catalytic enantioselective intermolecular cycloadditions of 2-diazo-3,6-diketoester-derived carbonyl ylides with alkene dipolarophiles
David M. Hodgson, Tobias Brückl, Rebecca Glen, Agnès H. Labande, Deborah A. Selden, Alexander G. Dossetter, and Alison J. Redgrave
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5450–5454. Published online 2004 March 22. doi: 10.1073/pnas.0307274101.
PMCID: PMC397403
Rhodium-catalyzed asymmetric ring opening reactions of oxabicyclic alkenes: Catalyst and substrate studies leading to a mechanistic working model
Mark Lautens and Keith Fagnou
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5455–5460. Published online 2004 April 5. doi: 10.1073/pnas.0307271101.
PMCID: PMC397404
Helically chiral polymers: A class of ligands for asymmetric catalysis
Michael Reggelin, Sebastian Doerr, Martin Klussmann, Melanie Schultz, and Michael Holbach
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5461–5466. Published online 2004 March 30. doi: 10.1073/pnas.0307443101.
PMCID: PMC397405
Effect of sulfide structure on enantioselectivity in catalytic asymmetric epoxidation of aldehydes: Mechanistic insights and implications
Varinder K. Aggarwal, Jonathan Charmant, Leo Dudin, Marina Porcelloni, and Jeffery Richardson
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5467–5471. Published online 2004 March 19. doi: 10.1073/pnas.0307559101.
PMCID: PMC397406
Catalytic asymmetric reactions for organic synthesis: The combined C—H activation/Cope rearrangement
Huw M. L. Davies and Qihui Jin
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5472–5475. Published online 2004 March 15. doi: 10.1073/pnas.0307556101.
PMCID: PMC397407
Air-stable, storable, and highly efficient chiral zirconium catalysts for enantioselective Mannich-type, aza Diels–Alder, aldol, and hetero Diels–Alder reactions
Shū Kobayashi, Masaharu Ueno, Susumu Saito, Yumiko Mizuki, Haruro Ishitani, and Yasuhiro Yamashita
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5476–5481. Published online 2004 April 5. doi: 10.1073/pnas.0307870101.
PMCID: PMC397408
From the Cover: Asymmetric Catalysis Special Feature Part I:
Enantioselective organocatalytic construction of pyrroloindolines by a cascade addition–cyclization strategy: Synthesis of (–)-flustramine B
Joel F. Austin, Sung-Gon Kim, Christopher J. Sinz, Wen-Jing Xiao, and David W. C. MacMillan
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5482–5487. Published online 2004 April 5. doi: 10.1073/pnas.0308177101.
PMCID: PMC397409
Editorial
Asymmetric Catalysis
Jack Halpern and Barry M. Trost
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5347. doi: 10.1073/pnas.0401811101.
PMCID: PMC397383
Perspective
Asymmetric catalysis: An enabling science
Barry M. Trost
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5348–5355. Published online 2004 February 27. doi: 10.1073/pnas.0306715101.
PMCID: PMC397384
Toward efficient asymmetric hydrogenation: Architectural and functional engineering of chiral molecular catalysts
Ryoji Noyori, Masato Kitamura, and Takeshi Ohkuma
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5356–5362. Published online 2004 March 19. doi: 10.1073/pnas.0307928100.
PMCID: PMC397385
Catalytic asymmetric synthesis of all-carbon quaternary stereocenters
Christopher J. Douglas and Larry E. Overman
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5363–5367. Published online 2004 January 14. doi: 10.1073/pnas.0307113101.
PMCID: PMC397386
Asymmetric catalysis in complex target synthesis
Mark S. Taylor and Eric N. Jacobsen
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5368–5373. Published online 2004 March 12. doi: 10.1073/pnas.0307893101.
PMCID: PMC397387
From the Cover: ASYMMETRIC CATALYSIS SPECIAL FEATURE PART I
From the Cover: Asymmetric Catalysis Special Feature Part I:
Enantioselective organocatalytic construction of pyrroloindolines by a cascade addition–cyclization strategy: Synthesis of (–)-flustramine B
Joel F. Austin, Sung-Gon Kim, Christopher J. Sinz, Wen-Jing Xiao, and David W. C. MacMillan
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5482–5487. Published online 2004 April 5. doi: 10.1073/pnas.0308177101.
PMCID: PMC397409
Biographies
Biography of James L. Van Etten
Christen Brownlee
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5315–5317. Published online 2004 April 5. doi: 10.1073/pnas.0401846101.
PMCID: PMC399311
Biography of Zhu Chen
David Bradley
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5325–5327. Published online 2004 April 5. doi: 10.1073/pnas.0401849101.
PMCID: PMC399312
Biography of Joseph S. Takahashi
Melissa Marino
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5336–5338. Published online 2004 April 5. doi: 10.1073/pnas.0401895101.
PMCID: PMC399313
Physical Sciences
Chemistry
O-nitroso aldol synthesis: Catalytic enantioselective route to α-aminooxy carbonyl compounds via enamine intermediate
Norie Momiyama, Hiromi Torii, Susumu Saito, and Hisashi Yamamoto
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5374–5378. Published online 2004 April 5. doi: 10.1073/pnas.0307785101.
PMCID: PMC397388
Mechanistic studies of the molybdenum-catalyzed asymmetric alkylation reaction
David L. Hughes, Guy C. Lloyd-Jones, Shane W. Krska, Laure Gouriou, Veronique D. Bonnet, Kevin Jack, Yongkui Sun, David J. Mathre, and Robert A. Reamer
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5379–5384. Published online 2004 March 31. doi: 10.1073/pnas.0306918101.
PMCID: PMC397389
Asymmetric hydrogenation of α,β-unsaturated phosphonates with Rh-BisP* and Rh-MiniPHOS catalysts: Scope and mechanism of the reaction
Ilya D. Gridnev, Masaya Yasutake, Tsuneo Imamoto, and Irina P. Beletskaya
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5385–5390. Published online 2004 March 15. doi: 10.1073/pnas.0306993101.
PMCID: PMC397390
Asymmetric hetero-Diels–Alder reaction catalyzed by dirhodium(II) carboxamidates
Michael P. Doyle, Marcela Valenzuela, and Penglin Huang
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5391–5395. Published online 2004 April 1. doi: 10.1073/pnas.0307025101.
PMCID: PMC397391
An efficient, palladium-catalyzed, enantioselective synthesis of (2R)-3-butene-1,2-diol and its use in highly selective Heck reactions
Natasha Cheeseman, Martin Fox, Mark Jackson, Ian C. Lennon, and Graham Meek
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5396–5399. Published online 2004 February 11. doi: 10.1073/pnas.0307047101.
PMCID: PMC397392
OH–Pd(0) interaction as a stabilizing factor in palladium-catalyzed allylic alkylations
Kristina Hallman, Anders Frölander, Tebikie Wondimagegn, Mats Svensson, and Christina Moberg
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5400–5404. Published online 2004 April 5. doi: 10.1073/pnas.0307084101.
PMCID: PMC397393
Catalytic asymmetric addition of diorganozinc reagents to N-phosphinoylalkylimines
Alexandre Côté, Alessandro A. Boezio, and André B. Charette
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5405–5410. Published online 2004 April 2. doi: 10.1073/pnas.0307096101.
PMCID: PMC397394
New biphenol-based, fine-tunable monodentate phosphoramidite ligands for catalytic asymmetric transformations
Zihao Hua, Victor C. Vassar, Hojae Choi, and Iwao Ojima
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5411–5416. Published online 2004 March 12. doi: 10.1073/pnas.0307101101.
PMCID: PMC397395
Highly enantioselective alkyne additions to aldehydes in the presence of 1,1′-bi-2-naphthol and hexamethylphosphoramide
Ge Gao, Ru-Gang Xie, and Lin Pu
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5417–5420. Published online 2004 March 16. doi: 10.1073/pnas.0307136101.
PMCID: PMC397396
Desymmetrization of enone-diones via rhodium-catalyzed diastereo- and enantioselective tandem conjugate addition-aldol cyclization
Brian M. Bocknack, Long-Cheng Wang, and Michael J. Krische
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5421–5424. Published online 2004 March 15. doi: 10.1073/pnas.0307120101.
PMCID: PMC397397
Catalytic asymmetric addition of diphenylzinc to cyclic α,β-unsaturated ketones
Hongmei Li, Celina García, and Patrick J. Walsh
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5425–5427. Published online 2004 April 5. doi: 10.1073/pnas.0307119101.
PMCID: PMC397398
Solid-phase synthesis of chiral 3,4-diazaphospholanes and their application to catalytic asymmetric allylic alkylation
Clark R. Landis and Thomas P. Clark
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5428–5432. Published online 2004 February 25. doi: 10.1073/pnas.0307572100.
PMCID: PMC397399
Enantioselective syntheses and biological studies of aeruginosin 298-A and its analogs: Application of catalytic asymmetric phase-transfer reaction
Yuhei Fukuta, Takashi Ohshima, Vijay Gnanadesikan, Tomoyuki Shibuguchi, Tetsuhiro Nemoto, Takaya Kisugi, Tatsufumi Okino, and Masakatsu Shibasaki
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5433–5438. Published online 2004 March 2. doi: 10.1073/pnas.0307154101.
PMCID: PMC397400
Chiral phosphoramide-catalyzed, enantioselective, directed cross-aldol reactions of aldehydes
Scott E. Denmark and Tommy Bui
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5439–5444. Published online 2004 April 5. doi: 10.1073/pnas.0307212101.
PMCID: PMC397401
Mechanistic studies on the catalytic cycle of rhodium-catalyzed asymmetric 1,4-addition of aryltitanate reagents to α,β-unsaturated ketones
Norihito Tokunaga, Kazuhiro Yoshida, and Tamio Hayashi
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5445–5449. Published online 2004 February 23. doi: 10.1073/pnas.0307260101.
PMCID: PMC397402
Catalytic enantioselective intermolecular cycloadditions of 2-diazo-3,6-diketoester-derived carbonyl ylides with alkene dipolarophiles
David M. Hodgson, Tobias Brückl, Rebecca Glen, Agnès H. Labande, Deborah A. Selden, Alexander G. Dossetter, and Alison J. Redgrave
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5450–5454. Published online 2004 March 22. doi: 10.1073/pnas.0307274101.
PMCID: PMC397403
Rhodium-catalyzed asymmetric ring opening reactions of oxabicyclic alkenes: Catalyst and substrate studies leading to a mechanistic working model
Mark Lautens and Keith Fagnou
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5455–5460. Published online 2004 April 5. doi: 10.1073/pnas.0307271101.
PMCID: PMC397404
Helically chiral polymers: A class of ligands for asymmetric catalysis
Michael Reggelin, Sebastian Doerr, Martin Klussmann, Melanie Schultz, and Michael Holbach
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5461–5466. Published online 2004 March 30. doi: 10.1073/pnas.0307443101.
PMCID: PMC397405
Effect of sulfide structure on enantioselectivity in catalytic asymmetric epoxidation of aldehydes: Mechanistic insights and implications
Varinder K. Aggarwal, Jonathan Charmant, Leo Dudin, Marina Porcelloni, and Jeffery Richardson
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5467–5471. Published online 2004 March 19. doi: 10.1073/pnas.0307559101.
PMCID: PMC397406
Catalytic asymmetric reactions for organic synthesis: The combined C—H activation/Cope rearrangement
Huw M. L. Davies and Qihui Jin
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5472–5475. Published online 2004 March 15. doi: 10.1073/pnas.0307556101.
PMCID: PMC397407
Air-stable, storable, and highly efficient chiral zirconium catalysts for enantioselective Mannich-type, aza Diels–Alder, aldol, and hetero Diels–Alder reactions
Shū Kobayashi, Masaharu Ueno, Susumu Saito, Yumiko Mizuki, Haruro Ishitani, and Yasuhiro Yamashita
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5476–5481. Published online 2004 April 5. doi: 10.1073/pnas.0307870101.
PMCID: PMC397408
From the Cover: Asymmetric Catalysis Special Feature Part I:
Enantioselective organocatalytic construction of pyrroloindolines by a cascade addition–cyclization strategy: Synthesis of (–)-flustramine B
Joel F. Austin, Sung-Gon Kim, Christopher J. Sinz, Wen-Jing Xiao, and David W. C. MacMillan
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5482–5487. Published online 2004 April 5. doi: 10.1073/pnas.0308177101.
PMCID: PMC397409
Photocleavable fluorescent nucleotides for DNA sequencing on a chip constructed by site-specific coupling chemistry
Tae Seok Seo, Xiaopeng Bai, Hameer Ruparel, Zengmin Li, Nicholas J. Turro, and Jingyue Ju
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5488–5493. Published online 2004 April 2. doi: 10.1073/pnas.0401138101.
PMCID: PMC397410
From the Cover:
The HP-1 maquette: From an apoprotein structure to a structured hemoprotein designed to promote redox-coupled proton exchange
Steve S. Huang, Ronald L. Koder, Mitchell Lewis, A. Joshua Wand, and P. Leslie Dutton
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5536–5541. Published online 2004 March 31. doi: 10.1073/pnas.0306676101.
PMCID: PMC397418
Biological Sciences
Biochemistry
From the Cover:
Small interfering RNA production by enzymatic engineering of DNA (SPEED)
Biao Luo, Amanda D. Heard, and Harvey F. Lodish
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5494–5499. Published online 2004 March 15. doi: 10.1073/pnas.0400551101.
PMCID: PMC397411
Ubiquitylation of synphilin-1 and α-synuclein by SIAH and its presence in cellular inclusions and Lewy bodies imply a role in Parkinson's disease
Esti Liani, Allon Eyal, Eyal Avraham, Revital Shemer, Raymonde Szargel, Daniela Berg, Antje Bornemann, Olaf Riess, Christopher A. Ross, Ruth Rott, and Simone Engelender
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5500–5505. Published online 2004 April 2. doi: 10.1073/pnas.0401081101.
PMCID: PMC397412
Metalloregulation of yeast membrane steroid receptor homologs
Thomas J. Lyons, Nancy Y. Villa, Lisa M. Regalla, Brian R. Kupchak, Anna Vagstad, and David J. Eide
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5506–5511. Published online 2004 April 1. doi: 10.1073/pnas.0306324101.
PMCID: PMC397413
Acetylcholinesterase/paraoxonase genotype and expression predict anxiety scores in Health, Risk Factors, Exercise Training, and Genetics study
Ella H. Sklan, Alexander Lowenthal, Mira Korner, Ya'acov Ritov, Daniel M. Landers, Tuomo Rankinen, Claude Bouchard, Arthur S. Leon, Treva Rice, D. C. Rao, Jack H. Wilmore, James S. Skinner, and Hermona Soreq
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5512–5517. Published online 2004 April 1. doi: 10.1073/pnas.0307659101.
PMCID: PMC397414
Oxygen and the copper chaperone CCS regulate posttranslational activation of Cu,Zn superoxide dismutase
Nina M. Brown, Andrew S. Torres, Peter E. Doan, and Thomas V. O'Halloran
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5518–5523. Published online 2004 April 2. doi: 10.1073/pnas.0401175101.
PMCID: PMC397415
Temporal linkage between the phenotypic and genomic responses to caloric restriction
Joseph M. Dhahbi, Hyon-Jeen Kim, Patricia L. Mote, Robert J. Beaver, and Stephen R. Spindler
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5524–5529. Published online 2004 March 25. doi: 10.1073/pnas.0305300101.
PMCID: PMC397416
Biophysics
Small potassium ion channel proteins encoded by chlorella viruses
Ming Kang, Anna Moroni, Sabrina Gazzarrini, Dario DiFrancesco, Gerhard Thiel, Maria Severino, and James L. Van Etten
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5318–5324. Published online 2004 February 4. doi: 10.1073/pnas.0307824100.
PMCID: PMC397378
Photocleavable fluorescent nucleotides for DNA sequencing on a chip constructed by site-specific coupling chemistry
Tae Seok Seo, Xiaopeng Bai, Hameer Ruparel, Zengmin Li, Nicholas J. Turro, and Jingyue Ju
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5488–5493. Published online 2004 April 2. doi: 10.1073/pnas.0401138101.
PMCID: PMC397410
Modulation of energy-dependent quenching of excitons in antennae of higher plants
Thomas J. Avenson, Jeffrey A. Cruz, and David M. Kramer
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5530–5535. Published online 2004 April 2. doi: 10.1073/pnas.0401269101.
PMCID: PMC397417
From the Cover:
The HP-1 maquette: From an apoprotein structure to a structured hemoprotein designed to promote redox-coupled proton exchange
Steve S. Huang, Ronald L. Koder, Mitchell Lewis, A. Joshua Wand, and P. Leslie Dutton
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5536–5541. Published online 2004 March 31. doi: 10.1073/pnas.0306676101.
PMCID: PMC397418
Cell Biology
Myosin V processivity: Multiple kinetic pathways for head-to-head coordination
Josh E. Baker, Elena B. Krementsova, Guy G. Kennedy, Amy Armstrong, Kathleen M. Trybus, and David M. Warshaw
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5542–5546. Published online 2004 March 31. doi: 10.1073/pnas.0307247101.
PMCID: PMC397419
COMP-Ang1: A designed angiopoietin-1 variant with nonleaky angiogenic activity
Chung-Hyun Cho, Richard A. Kammerer, Hyuek Jong Lee, Michel O. Steinmetz, Young Shin Ryu, Sung Ho Lee, Kunio Yasunaga, Kyung-Tae Kim, Injune Kim, Han-Ho Choi, Won Kim, Sung Hyun Kim, Sung Kwang Park, Gyun Min Lee, and Gou Young Koh
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5547–5552. Published online 2004 April 1. doi: 10.1073/pnas.0307574101.
PMCID: PMC397420
Designed angiopoietin-1 variant, COMP-Ang1, protects against radiation-induced endothelial cell apoptosis
Chung-Hyun Cho, Richard A. Kammerer, Hyuek Jong Lee, Kunio Yasunaga, Kyung-Tae Kim, Han-Ho Choi, Won Kim, Sung Hyun Kim, Sung Kwang Park, Gyun Min Lee, and Gou Young Koh
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5553–5558. Published online 2004 April 1. doi: 10.1073/pnas.0307575101.
PMCID: PMC397421
RNA interference of achaete–scute homolog 1 in mouse prostate neuroendocrine cells reveals its gene targets and DNA binding sites
Yan Hu, Ting Wang, Gary D. Stormo, and Jeffrey I. Gordon
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5559–5564. Published online 2004 April 1. doi: 10.1073/pnas.0306988101.
PMCID: PMC397422
Direct continuities between cisternae at different levels of the Golgi complex in glucose-stimulated mouse islet beta cells
Brad J. Marsh, Niels Volkmann, J. Richard McIntosh, and Kathryn E. Howell
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5565–5570. Published online 2004 April 2. doi: 10.1073/pnas.0401242101.
PMCID: PMC397423
Myristoylated Naked2 escorts transforming growth factor α to the basolateral plasma membrane of polarized epithelial cells
Cunxi Li, Jeffrey L. Franklin, Ramona Graves-Deal, W. Gray Jerome, Zheng Cao, and Robert J. Coffey
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5571–5576. Published online 2004 April 2. doi: 10.1073/pnas.0401294101.
PMCID: PMC397424
From the Cover:
Suppression of nuclear oscillations in Saccharomyces cerevisiae expressing Glu tubulin
A. C. Badin-Larçon, C. Boscheron, J. M. Soleilhac, M. Piel, C. Mann, E. Denarier, A. Fourest-Lieuvin, L. Lafanechère, M. Bornens, and D. Job
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5577–5582. Published online 2004 March 18. doi: 10.1073/pnas.0307917101.
PMCID: PMC397425
Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growth
Nicole K. Noren, Mark Lu, Andrew L. Freeman, Mitchell Koolpe, and Elena B. Pasquale
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5583–5588. Published online 2004 April 5. doi: 10.1073/pnas.0401381101.
PMCID: PMC397426
Evolution
Genome-wide comparative analysis of the transposable elements in the related species Arabidopsis thaliana and Brassica oleracea
Xiaoyu Zhang and Susan R. Wessler
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5589–5594. Published online 2004 April 2. doi: 10.1073/pnas.0401243101.
PMCID: PMC397431
Maternal investment affects offspring phenotypic plasticity in a viviparous cockroach
Glenn L. Holbrook and Coby Schal
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5595–5597. Published online 2004 April 2. doi: 10.1073/pnas.0400209101.
PMCID: PMC397435
Immunology
Recognition of single-stranded RNA viruses by Toll-like receptor 7
Jennifer M. Lund, Lena Alexopoulou, Ayuko Sato, Margaret Karow, Niels C. Adams, Nicholas W. Gale, Akiko Iwasaki, and Richard A. Flavell
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5598–5603. Published online 2004 March 19. doi: 10.1073/pnas.0400937101.
PMCID: PMC397437
Inositol (1,4,5) trisphosphate 3 kinase B controls positive selection of T cells and modulates Erk activity
Ben G. Wen, Mathew T. Pletcher, Masaki Warashina, Sun Hui Choe, Niusha Ziaee, Tim Wiltshire, Karsten Sauer, and Michael P. Cooke
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5604–5609. Published online 2004 April 2. doi: 10.1073/pnas.0306907101.
PMCID: PMC397439
Selective expression of IL-7 receptor on memory T cells identifies early CD40L-dependent generation of distinct CD8+ memory T cell subsets
Katharina M. Huster, Verena Busch, Matthias Schiemann, Kathrin Linkemann, Kristen M. Kerksiek, Hermann Wagner, and Dirk H. Busch
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5610–5615. Published online 2004 March 25. doi: 10.1073/pnas.0308054101.
PMCID: PMC397444
Distinct cell types control lymphoid subset development by means of IL-15 and IL-15 receptor α expression
Kimberly S. Schluns, Elizabeth C. Nowak, Arturo Cabrera-Hernandez, Lynn Puddington, Leo Lefrançois, and Hector L. Aguila
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5616–5621. Published online 2004 April 1. doi: 10.1073/pnas.0307442101.
PMCID: PMC397446
Medical Sciences
All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia
Zhi-Xiang Shen, Zhan-Zhong Shi, Jing Fang, Bai-Wei Gu, Jun-Min Li, Yong-Mei Zhu, Jing-Yi Shi, Pei-Zheng Zheng, Hua Yan, Yuan-Fang Liu, Yu Chen, Yang Shen, Wen Wu, Wei Tang, Samuel Waxman, Hugues de Thé, Zhen-Yi Wang, Sai-Juan Chen, and Zhu Chen
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5328–5335. Published online 2004 March 24. doi: 10.1073/pnas.0400053101.
PMCID: PMC397380
From the Cover:
Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cycling
Federica del Monte, Djamel Lebeche, J. Luis Guerrero, Tsuyoshi Tsuji, Angelia A. Doye, Judith K. Gwathmey, and Roger J. Hajjar
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5622–5627. Published online 2004 March 25. doi: 10.1073/pnas.0305778101.
PMCID: PMC397450
A target site for template-based design of measles virus entry inhibitors
Richard K. Plemper, Karl J. Erlandson, Ami S. Lakdawala, Aiming Sun, Andrew Prussia, Jutatip Boonsombat, Esin Aki-Sener, Ismail Yalcin, Ilkay Yildiz, Ozlem Temiz-Arpaci, Betul Tekiner, Dennis C. Liotta, James P. Snyder, and Richard W. Compans
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5628–5633. Published online 2004 March 31. doi: 10.1073/pnas.0308520101.
PMCID: PMC397452
Canonical pathway of nuclear factor κB activation selectively regulates proinflammatory and prothrombotic responses in human atherosclerosis
Claudia Monaco, Evangelos Andreakos, Serafim Kiriakidis, Claudia Mauri, Colin Bicknell, Brian Foxwell, Nicholas Cheshire, Ewa Paleolog, and Marc Feldmann
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5634–5639. Published online 2004 April 2. doi: 10.1073/pnas.0401060101.
PMCID: PMC397455
Microbiology
Roles of substrate availability and infection of resting and activated CD4+ T cells in transmission and acute simian immunodeficiency virus infection
Zhi-Qiang Zhang, Stephen W. Wietgrefe, Qingsheng Li, Marta Dykhuizen Shore, Lijie Duan, Cavan Reilly, Jeffrey D. Lifson, and Ashley T. Haase
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5640–5645. Published online 2004 April 2. doi: 10.1073/pnas.0308425101.
PMCID: PMC397458
Comparison of the genome of the oral pathogen Treponema denticola with other spirochete genomes
Rekha Seshadri, Garry S. A. Myers, Hervé Tettelin, Jonathan A. Eisen, John F. Heidelberg, Robert J. Dodson, Tanja M. Davidsen, Robert T. DeBoy, Derrick E. Fouts, Dan H. Haft, Jeremy Selengut, Qinghu Ren, Lauren M. Brinkac, Ramana Madupu, Jamie Kolonay, Scott A. Durkin, Sean C. Daugherty, Jyoti Shetty, Alla Shvartsbeyn, Elizabeth Gebregeorgis, Keita Geer, Getahun Tsegaye, Joel Malek, Bola Ayodeji, Sofiya Shatsman, Michael P. McLeod, David Šmajs, Jerrilyn K. Howell, Sangita Pal, Anita Amin, Pankaj Vashisth, Thomas Z. McNeill, Qin Xiang, Erica Sodergren, Ernesto Baca, George M. Weinstock, Steven J. Norris, Claire M. Fraser, and Ian T. Paulsen
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5646–5651. Published online 2004 April 2. doi: 10.1073/pnas.0307639101.
PMCID: PMC397461
A single amino acid substitution in human APOBEC3G antiretroviral enzyme confers resistance to HIV-1 virion infectivity factor-induced depletion
Hongzhan Xu, Evguenia S. Svarovskaia, Rebekah Barr, Yijun Zhang, Mohammad A. Khan, Klaus Strebel, and Vinay K. Pathak
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5652–5657. Published online 2004 March 30. doi: 10.1073/pnas.0400830101.
PMCID: PMC397464
Neuroscience
PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues
Seung-Hee Yoo, Shin Yamazaki, Phillip L. Lowrey, Kazuhiro Shimomura, Caroline H. Ko, Ethan D. Buhr, Sandra M. Siepka, Hee-Kyung Hong, Won Jun Oh, Ook Joon Yoo, Michael Menaker, and Joseph S. Takahashi
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5339–5346. Published online 2004 February 12. doi: 10.1073/pnas.0308709101.
PMCID: PMC397382
Beyond sensory images: Object-based representation in the human ventral pathway
Pietro Pietrini, Maura L. Furey, Emiliano Ricciardi, M. Ida Gobbini, W.-H. Carolyn Wu, Leonardo Cohen, Mario Guazzelli, and James V. Haxby
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5658–5663. Published online 2004 April 2. doi: 10.1073/pnas.0400707101.
PMCID: PMC397466
A single cocaine exposure enhances both opioid reward and aversion through a ventral tegmental area-dependent mechanism
Joseph A. Kim, Kelly A. Pollak, Gregory O. Hjelmstad, and Howard L. Fields
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5664–5669. Published online 2004 April 2. doi: 10.1073/pnas.0401373101.
PMCID: PMC397468
Classification of natural textures in echolocation
Jan-Eric Grunwald, Sven Schörnich, and Lutz Wiegrebe
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5670–5674. Published online 2004 April 1. doi: 10.1073/pnas.0308029101.
PMCID: PMC397469
Physiology
Cumulative inactivation of N-type CaV2.2 calcium channels modified by alternative splicing
Christopher Thaler, Annette C. Gray, and Diane Lipscombe
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5675–5679. Published online 2004 April 1. doi: 10.1073/pnas.0303402101.
PMCID: PMC397472
Plant Biology
Induction of oral tolerance to prevent diabetes with transgenic plants requires glutamic acid decarboxylase (GAD) and IL-4
Shengwu Ma, Yan Huang, ZiQin Yin, Rima Menassa, James E. Brandle, and Anthony M. Jevnikar
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5680–5685. Published online 2004 March 31. doi: 10.1073/pnas.0307420101.
PMCID: PMC397475
Psychology
The change of the brain activation patterns as children learn algebra equation solving
Yulin Qin, Cameron S. Carter, Eli M. Silk, V. Andrew Stenger, Kate Fissell, Adam Goode, and John R. Anderson
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5686–5691. Published online 2004 April 2. doi: 10.1073/pnas.0401227101.
PMCID: PMC397478
Social Sciences
Anthropology
Kusunda: An Indo-Pacific language in Nepal
Paul Whitehouse, Timothy Usher, Merritt Ruhlen, and William S.-Y. Wang
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5692–5695. Published online 2004 March 31. doi: 10.1073/pnas.0400233101.
PMCID: PMC397480
Corrections
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5696. doi: 10.1073/pnas.0400920101.
PMCID: PMC397482
Corrects: Peter A. Cotton. Avian migration phenology and global climate change. Proc Natl Acad Sci U S A. 2003 October 14; 100(21): 12219–12222.
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5696. doi: 10.1073/pnas.0401592101.
PMCID: PMC397484
Corrects: David L. Smith, et al. Persistent colonization and the spread of antibiotic resistance in nosocomial pathogens: Resistance is a regional problem. Proc Natl Acad Sci U S A. 2004 March 9; 101(10): 3709–3714.
Proc Natl Acad Sci U S A. 2004 April 13; 101(15): 5696. doi: 10.1073/pnas.0401218101.
PMCID: PMC397486
Corrects: Maki Ohgishi, et al. Functional analysis of each blue light receptor, cry1, cry2, phot1, and phot2, by using combinatorial multiple mutants in Arabidopsis. Proc Natl Acad Sci U S A. 2004 February 24; 101(8): 2223–2228.
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