Diverse strategies for tetracycline-regulated inducible gene expression.

The viruses in all of us: characteristics and biological significance of human endogenous retrovirus sequences.

Rapid retroviral delivery of tetracycline-inducible genes in a single autoregulatory cassette.

Crystal structure at 2.6-A resolution of human macrophage migration inhibitory factor.

Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine.

Quantal acetylcholine release induced by mediatophore transfection.

Absolute mRNA levels and transcriptional initiation rates in Saccharomyces cerevisiae.

Immunotargeting of antioxidant enzyme to the pulmonary endothelium.

The rat extracellular superoxide dismutase dimer is converted to a tetramer by the exchange of a single amino acid.

A structural model for a homeotic protein-extradenticle-DNA complex accounts for the choice of HOX protein in the heterodimer.

Malignant conversion of chemically transformed normal human cells.

Traumatic brain damage prevented by the non-N-methyl-D-aspartate antagonist 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo[f] quinoxaline.

Arachidonate lipoxygenases as essential regulators of cell survival and apoptosis.

Long-term culture of lymphohematopoietic stem cells.

Expression of a recoded nuclear gene inserted into yeast mitochondrial DNA is limited by mRNA-specific translational activation.

Ultraviolet-B photodestruction of a light-harvesting complex.

Functional testicular tissue does not masculinize development of the zebra finch song system.

Inhibition of immunoglobulin folding and secretion by dominant negative BiP ATPase mutants.

Evidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signaling.

Cloning of thermostable DNA polymerases from hyperthermophilic marine Archaea with emphasis on Thermococcus sp. 9 degrees N-7 and mutations affecting 3'-5' exonuclease activity.

Successful external fertilization in turbulent environments.

Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain.

Late Holocene human-induced modifications to a central Polynesian island ecosystem.

Heat-shock protein 104 expression is sufficient for thermotolerance in yeast.

Adenine phosphoribosyltransferase-deficient mice develop 2,8-dihydroxyadenine nephrolithiasis.

The transcription factors c-myb and GATA-2 act independently in the regulation of normal hematopoiesis.

A mutation that allows endosperm development without fertilization.

Bcl-2 interrupts the ceramide-mediated pathway of cell death.

NMR studies of muscle glycogen synthesis in insulin-resistant offspring of parents with non-insulin-dependent diabetes mellitus immediately after glycogen-depleting exercise.

Expression of Norwalk virus capsid protein in transgenic tobacco and potato and its oral immunogenicity in mice.

Direct observation of iron-induced conformational changes of mitochondrial DNA by high-resolution field-emission in-lens scanning electron microscopy.

Expression of a renal type I sodium/phosphate transporter (NaPi-1) induces a conductance in Xenopus oocytes permeable for organic and inorganic anions.

Ras2 signals via the Cdc42/Ste20/mitogen-activated protein kinase module to induce filamentous growth in Saccharomyces cerevisiae.

Three-dimensional structure of human protein kinase C interacting protein 1, a member of the HIT family of proteins.

Insights into antibody catalysis: structure of an oxygenation catalyst at 1.9-angstrom resolution.

Near-membrane [Ca2+] transients resolved using the Ca2+ indicator FFP18.

Disruption of the aldolase A tetramer into catalytically active monomers.

Ancestral major histocompatibility complex DRB genes beget conserved patterns of localized polymorphisms.

Phenotypic variations among paternal centrosomes expressed within the zygote as disparate microtubule lengths and sperm aster organization: correlations between centrosome activity and developmental success.

Vip3A, a novel Bacillus thuringiensis vegetative insecticidal protein with a wide spectrum of activities against lepidopteran insects.

Extremely sensitive, background-free gene detection using binary probes and beta replicase.

Molecular cloning and expression of a cyclic AMP-activated chloride conductance regulator: a novel ATP-binding cassette transporter.

Mechanism of photoreceptor cGMP phosphodiesterase inhibition by its gamma-subunits.

Intrasarcomere [Ca2+] gradients in ventricular myocytes revealed by high speed digital imaging microscopy.

Recombinational repair of gaps in DNA is asymmetric in Ustilago maydis and can be explained by a migrating D-loop model.

Differential effects of staphylococcal toxic shock syndrome toxin-1 on B cell apoptosis.

Targeted disruption of the mZP3 gene results in production of eggs lacking a zona pellucida and infertility in female mice.

Purification and cDNA cloning of a second apoptosis-related cysteine protease that cleaves and activates sterol regulatory element binding proteins.

Conserved motifs in prokaryotic and eukaryotic polypeptide release factors: tRNA-protein mimicry hypothesis.

Evolutionary relationships of the coelacanth, lungfishes, and tetrapods based on the 28S ribosomal RNA gene.

Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma.

Irreversible inactivation of interleukin 2 in a pump-based delivery environment.

The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains.

The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu,Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease.

Ca2+ channel blockers modulate metabolism of collagens within the extracellular matrix.

A locus on chromosome 7 determines myocardial cell necrosis and calcification (dystrophic cardiac calcinosis) in mice.

Subcellular imaging of intramitochondrial Ca2+ with recombinant targeted aequorin: significance for the regulation of pyruvate dehydrogenase activity.

Cellular and subcellular localization of the vasopressin- regulated urea transporter in rat kidney.

Host-parasite dynamics and outgrowth of virus containing a single K70R amino acid change in reverse transcriptase are responsible for the loss of human immunodeficiency virus type 1 RNA load suppression by zidovudine.

The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression.

The protection receptor for IgG catabolism is the beta2-microglobulin-containing neonatal intestinal transport receptor.

Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells.

The replication initiator protein pi of the plasmid R6K specifically interacts with the host-encoded helicase DnaB.

Regulation of cardiac sodium-calcium exchanger by beta-adrenergic agonists.

Apoptosis of nur77/N10-transgenic thymocytes involves the Fas/Fas ligand pathway.

Dopamine transporters are markedly reduced in Lesch-Nyhan disease in vivo.

Interaction of cyclooxygenases with an apoptosis- and autoimmunity-associated protein.

Molecular basis for dysfunction of some mutant forms of methylmalonyl-CoA mutase: deductions from the structure of methionine synthase.

Microfabricated structures for integrated DNA analysis.

Ordered yeast artificial chromosome clones representing the Dictyostelium discoideum genome.

The timing of synaptic vesicle endocytosis.

A loop-loop "kissing" complex is the essential part of the dimer linkage of genomic HIV-1 RNA.

Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus.

Glutamate receptor blockade at cortical synapses disrupts development of thalamocortical and columnar organization in somatosensory cortex.

Active barnase variants with completely random hydrophobic cores.

Pea formaldehyde-active class III alcohol dehydrogenase: common derivation of the plant and animal forms but not of the corresponding ethanol-active forms (classes I and P).

Vitamin E prevents oxidative modification of brain and lymphocyte band 3 proteins during aging.

Nitric oxide inhibits creatine kinase and regulates rat heart contractile reserve.

Two mutant prion proteins expressed in cultured cells acquire biochemical properties reminiscent of the scrapie isoform.

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42.

Two mitochondrial group I introns in a metazoan, the sea anemone Metridium senile: one intron contains genes for subunits 1 and 3 of NADH dehydrogenase.

A novel iron-regulated metal transporter from plants identified by functional expression in yeast.

Cellular stress inhibits transposition of the yeast retrovirus-like element Ty3 by a ubiquitin-dependent block of virus-like particle formation.

The contrasting roles of ICE family proteases and interleukin-1beta in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase down-regulation.

A functional peptide encoded in the Escherichia coli 23S rRNA.

A truncated mutant (residues 58-140) of the hepatitis B virus X protein retains transactivation function.

Characterization of a unique variant of bat rabies virus responsible for newly emerging human cases in North America.

Congruence of fatty acid methyl ester profiles and morphological characters of arbuscular mycorrhizal fungi in Gigasporaceae.

Constitutively active human Notch1 binds to the transcription factor CBF1 and stimulates transcription through a promoter containing a CBF1-responsive element.

OB protein binds specifically to the choroid plexus of mice and rats.

Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases.