A brief history of hemoglobins: plant, animal, protist, and bacteria.

Protein minimization: downsizing through mutation.

A new hemoglobin gene from soybean: a role for hemoglobin in all plants.

Minimizing a binding domain from protein A.

Modifications of RNA processing modulate the expression of hemoglobin genes.

Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors.

Second generation hybrid polar compounds are potent inducers of transformed cell differentiation.

A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide.

Mutation of a conserved serine in TM4 of opioid receptors confers full agonistic properties to classical antagonists.

Adenylate kinase complements nucleoside diphosphate kinase deficiency in nucleotide metabolism.

Maternal effort mediates the prevalence of trypanosomes in the offspring of a passerine bird.

A new adenoviral vector: Replacement of all viral coding sequences with 28 kb of DNA independently expressing both full-length dystrophin and beta-galactosidase.

Independent determination of symmetry and polarity in the Drosophila eye.

The nu gene acts cell-autonomously and is required for differentiation of thymic epithelial progenitors.

Miniature endplate current rise times less than 100 microseconds from improved dual recordings can be modeled with passive acetylcholine diffusion from a synaptic vesicle.

Stimulation of new bone formation by direct transfer of osteogenic plasmid genes.

Direct observation of fast protein folding: the initial collapse of apomyoglobin.

Segregation of DNA polynucleotide strands into sister chromatids and the use of endoreduplicated cells to track sister chromatid exchanges induced by crosslinks, alkylations, or x-ray damage.

An endogenous rate of time preference, the Penrose effect, and dynamic optimality of environmental quality.

Msn2p, a zinc finger DNA-binding protein, is the transcriptional activator of the multistress response in Saccharomyces cerevisiae.

Granzyme A is critical for recovery of mice from infection with the natural cytopathic viral pathogen, ectromelia.

Purification of the Drosophila RNA polymerase II general transcription factors.

Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes.

Behavior predicts genes structure in a wild primate group.

The embryonic transcription factor stage specific activator protein contains a potent bipartite activation domain that interacts with several RNA polymerase II basal transcription factors.

HslV-HslU: A novel ATP-dependent protease complex in Escherichia coli related to the eukaryotic proteasome.

Global properties of the mapping between local amino acid sequence and local structure in proteins.

Receptor stimulation causes slow inhibition of IRK1 inwardly rectifying K+ channels by direct protein kinase A-mediated phosphorylation.

A single mutation that increases maize seed weight.

Activating transcription from single stranded DNA.

Voltage gating and permeation in a gap junction hemichannel.

A JAK-STAT pathway regulates wing vein formation in Drosophila.

Two genes abrogate the inhibition of murine hepatocarcinogenesis by ovarian hormones.

Similarities and dissimilarities of phage genomes.

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage.

Scatter factor/hepatocyte growth factor as a regulator of skeletal muscle and neural crest development.

Conformational trapping in a membrane environment: a regulatory mechanism for protein activity?

The recombinant proregion of transforming growth factor beta1 (latency-associated peptide) inhibits active transforming growth factor beta1 in transgenic mice.

Calcium-dependent oligonucleotide antagonists specific for L-selectin.

Enhanced green fluorescence by the expression of an Aequorea victoria green fluorescent protein mutant in mono- and dicotyledonous plant cells.

Intercellular transfer of a glycosylphosphatidylinositol (GPI)-linked protein: release and uptake of CD4-GPI from recombinant adeno-associated virus-transduced HeLa cells.

Urokinase-type plasminogen activator is effective in fibrin clearance in the absence of its receptor or tissue-type plasminogen activator.

Complementation of the beige mutation in cultured cells by episomally replicating murine yeast artificial chromosomes.

RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell.

Serological analysis of Melan-A(MART-1), a melanocyte-specific protein homogeneously expressed in human melanomas.

Presynaptic association of Rad51 protein with selected sites in meiotic chromatin.

Cloning of a novel receptor expressed in rat prostate and ovary.

Leukotriene A4 hydrolase: protection from mechanism-based inactivation by mutation of tyrosine-378.

Structure and conformational changes of DNA topoisomerase II visualized by electron microscopy.

G1 arrest and down-regulation of cyclin E/cyclin-dependent kinase 2 by the protein kinase inhibitor staurosporine are dependent on the retinoblastoma protein in the bladder carcinoma cell line 5637.

Modulation of growth factor receptor function by isoform heterodimerization.

prlA suppressors in Escherichia coli relieve the proton electrochemical gradient dependency of translocation of wild-type precursors.

A tyrosine kinase profile of prostate carcinoma.

Molecular cloning of the Golgi apparatus uridine diphosphate-N-acetylglucosamine transporter from Kluyveromyces lactis.

Functional expression of mouse Mdr1 in an outer membrane permeability mutant of Escherichia coli.

Kinetics of self-assembling microtubules: an "inverse problem" in biochemistry.

Promotion of sleep mediated by the A2a-adenosine receptor and possible involvement of this receptor in the sleep induced by prostaglandin D2 in rats.

Substrate-bound agrin induces expression of acetylcholine receptor epsilon-subunit gene in cultured mammalian muscle cells.

Molecular cloning of a phosphotyrosine-independent ligand of the p56lck SH2 domain.

Membrane healing and restoration of contractility after mechanical injury in isolated skeletal muscle fibers of the frog.

A new endogenous natriuretic factor: LLU-alpha.

Evidence from disruption of the lmcpb gene array of Leishmania mexicana that cysteine proteinases are virulence factors.

PR-39, a proline-rich antibacterial peptide that inhibits phagocyte NADPH oxidase activity by binding to Src homology 3 domains of p47 phox.

Novel unconventional binding site in the variable region of immunoglobulins.

Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries.

The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region.

Magnetic resonance imaging (MRI) detection of the murine brain response to light: temporal differentiation and negative functional MRI changes.

A specific protein carboxyl methylesterase that demethylates phosphoprotein phosphatase 2A in bovine brain.

Mutations in the rotated abdomen locus affect muscle development and reveal an intrinsic asymmetry in Drosophila.

The association between glycosylphosphatidylinositol-anchored proteins and heterotrimeric G protein alpha subunits in lymphocytes.

An Escherichia coli chromosomal "addiction module" regulated by guanosine [corrected] 3',5'-bispyrophosphate: a model for programmed bacterial cell death.

An axoplasmic myosin with a calmodulin-like light chain.

Earliest evolution associated with closure of the Tropical American Seaway.

Human immunodeficiency virus tat gene transfer to the murine central nervous system using a replication-defective herpes simplex virus vector stimulates transforming growth factor beta 1 gene expression.

Behavioral genetics of thermosensation and hygrosensation in Drosophila.

Different cleavage sites are aligned differently in the active site of M1 RNA, the catalytic subunit of Escherichia coli RNase P.

Cell cycle-dependent modulation of telomerase activity in tumor cells.

Expression of corticotropin-releasing factor in inflamed tissue is required for intrinsic peripheral opioid analgesia.

The molecular basis of Sanfilippo syndrome type B.

Recombination leads to the rapid emergence of HIV-1 dually resistant mutants under selective drug pressure.

Inhibition of sustained gamma oscillations (35-80 Hz) by fast transient responses in cat visual cortex.

A single residue in the M2-M3 loop is a major determinant of coupling between binding and gating in neuronal nicotinic receptors.

Novel human DNA alkyltransferases obtained by random substitution and genetic selection in bacteria.

Deregulation of PAX-5 by translocation of the Emu enhancer of the IgH locus adjacent to two alternative PAX-5 promoters in a diffuse large-cell lymphoma.

Isolation of an immunodominant viral peptide that is endogenously bound to the stress protein GP96/GRP94.

Age-specific inbreeding depression and components of genetic variance in relation to the evolution of senescence.

Selenocysteine, identified as the penultimate C-terminal residue in human T-cell thioredoxin reductase, corresponds to TGA in the human placental gene.

Application of capillary electrophoresis-electrospray ionization mass spectometry in the determination of molecular diversity.

Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells.

Centromere mapping and orientation of the molecular linkage map of rice (Oryza sativa L.).

Modulation of AP-1 activity by the human progesterone receptor in endometrial adenocarcinoma cells.

Introduction of asymmetry in the naturally symmetric restriction endonuclease EcoRV to investigate intersubunit communication in the homodimeric protein.

Pantropic retroviral vectors integrate and express in cells of the malaria mosquito, Anopheles gambiae.

Subunit cleavage of mosquito pro-vitellogenin by a subtilisin-like convertase.

Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice.

Cell-type and promoter-context dependent retinoic acid receptor (RAR) redundancies for RAR beta 2 and Hoxa-1 activation in F9 and P19 cells can be artefactually generated by gene knockouts.

Genomic cloning of methylthioadenosine phosphorylase: a purine metabolic enzyme deficient in multiple different cancers.

Perpetuation of the agent of human granulocytic ehrlichiosis in a deer tick-rodent cycle.

The heart communicates with the kidney exclusively through the guanylyl cyclase-A receptor: acute handling of sodium and water in response to volume expansion.