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Volume 98(11);  May 22, 2001
Commentaries
FGF23, hypophosphatemia, and rickets: Has phosphatonin been found?
Gordon J. Strewler
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 5945–5946. doi: 10.1073/pnas.111154898.
PMCID: PMC33399
Glutamate antagonists: Deadly liaisons with cancer
Esper A. Cavalheiro and John W. Olney
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 5947–5948. doi: 10.1073/pnas.121179198.
PMCID: PMC33400
Factors affecting the developmental potential of cloned mammalian embryos
James C. Cross
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 5949–5951. doi: 10.1073/pnas.111182398.
PMCID: PMC33401
BRCA1 at a branch point
Jeffrey D. Parvin
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 5952–5954. doi: 10.1073/pnas.121184998.
PMCID: PMC33402
A new picture of life's history on Earth
Mark Newman
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 5955–5956. doi: 10.1073/pnas.121190498.
PMCID: PMC33403
Perspective
Precision in mouse behavior genetics
Donald Pfaff
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 5957–5960. Published online 2001 May 8. doi: 10.1073/pnas.101128598.
PMCID: PMC33404
Physical Sciences
Chemistry
Large vortex-like structure of dipole field in computer models of liquid water and dipole-bridge between biomolecules
Junichi Higo, Masaki Sasai, Hiroki Shirai, Haruki Nakamura, and Takaki Kugimiya
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 5961–5964. Published online 2001 May 8. doi: 10.1073/pnas.101516298.
PMCID: PMC33405
Quantification of the hydrophobic interaction by simulations of the aggregation of small hydrophobic solutes in water
Tanya M. Raschke, Jerry Tsai, and Michael Levitt
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 5965–5969. Published online 2001 May 15. doi: 10.1073/pnas.111158498.
PMCID: PMC33406
Designing surfaces that kill bacteria on contact
Joerg C. Tiller, Chun-Jen Liao, Kim Lewis, and Alexander M. Klibanov
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 5981–5985. Published online 2001 May 15. doi: 10.1073/pnas.111143098.
PMCID: PMC33409
Geology
Nondestructive, in situ, cellular-scale mapping of elemental abundances including organic carbon in permineralized fossils
C. K. Boyce, R. M. Hazen, and A. H. Knoll
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 5970–5974. doi: 10.1073/pnas.101130598.
PMCID: PMC33407
Geophysics
Desert dust suppressing precipitation: A possible desertification feedback loop
Daniel Rosenfeld, Yinon Rudich, and Ronen Lahav
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 5975–5980. Published online 2001 May 15. doi: 10.1073/pnas.101122798.
PMCID: PMC33408
Biological Sciences
Applied Biological Sciences
Designing surfaces that kill bacteria on contact
Joerg C. Tiller, Chun-Jen Liao, Kim Lewis, and Alexander M. Klibanov
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 5981–5985. Published online 2001 May 15. doi: 10.1073/pnas.111143098.
PMCID: PMC33409
An improved helper-dependent adenoviral vector allows persistent gene expression after intramuscular delivery and overcomes preexisting immunity to adenovirus
Domenico Maione, Carlo Della Rocca, Patrizia Giannetti, Roberta D'Arrigo, Laura Liberatoscioli, Laura L. Franlin, Volker Sandig, Gennaro Ciliberto, Nicola La Monica, and Rocco Savino
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 5986–5991. Published online 2001 May 15. doi: 10.1073/pnas.101122498.
PMCID: PMC33410
Using electroactive substrates to pattern the attachment of two different cell populations
Muhammad N. Yousaf, Benjamin T. Houseman, and Milan Mrksich
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 5992–5996. Published online 2001 May 15. doi: 10.1073/pnas.101112898.
PMCID: PMC33411
Biochemistry
Agonist-induced conformational changes in the G-protein-coupling domain of the β2 adrenergic receptor
Pejman Ghanouni, Jacqueline J. Steenhuis, David L. Farrens, and Brian K. Kobilka
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 5997–6002. Published online 2001 May 15. doi: 10.1073/pnas.101126198.
PMCID: PMC33412
Conformational coupling in the chemotaxis response regulator CheY
Martin Schuster, Ruth E. Silversmith, and Robert B. Bourret
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6003–6008. Published online 2001 May 15. doi: 10.1073/pnas.101571298.
PMCID: PMC33503
Reversibly locking a protein fold in an active conformation with a disulfide bond: Integrin αL I domains with high affinity and antagonist activity in vivo
Motomu Shimaoka, Chafen Lu, Roger T. Palframan, Ulrich H. von Andrian, Alison McCormack, Junichi Takagi, and Timothy A. Springer
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6009–6014. Published online 2001 May 15. doi: 10.1073/pnas.101130498.
PMCID: PMC33413
A type IB topoisomerase with DNA repair activities
Galina I. Belova, Rajendra Prasad, Sergei A. Kozyavkin, James A. Lake, Samuel H. Wilson, and Alexei I. Slesarev
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6015–6020. Published online 2001 May 15. doi: 10.1073/pnas.111040498.
PMCID: PMC33414
The structures of anthranilate synthase of Serratia marcescens crystallized in the presence of (i) its substrates, chorismate and glutamine, and a product, glutamate, and (ii) its end-product inhibitor, l-tryptophan
Glen Spraggon, Choel Kim, Xuong Nguyen-Huu, Muh-Ching Yee, Charles Yanofsky, and Stanley E. Mills
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6021–6026. doi: 10.1073/pnas.111150298.
PMCID: PMC33415
Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR
Jiafu Ou, Hua Tu, Bei Shan, Alvin Luk, Russell A. DeBose-Boyd, Yuriy Bashmakov, Joseph L. Goldstein, and Michael S. Brown
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6027–6032. doi: 10.1073/pnas.111138698.
PMCID: PMC33416
The arginine finger of RasGAP helps Gln-61 align the nucleophilic water in GAP-stimulated hydrolysis of GTP
Haluk Resat, T. P. Straatsma, David A. Dixon, and John H. Miller
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6033–6038. doi: 10.1073/pnas.091506998.
PMCID: PMC33417
Strong DNA binding by covalently linked dimeric Lac headpiece: Evidence for the crucial role of the hinge helices
Charalampos G. Kalodimos, Gert E. Folkers, Rolf Boelens, and Robert Kaptein
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6039–6044. Published online 2001 May 15. doi: 10.1073/pnas.101129898.
PMCID: PMC33418
Corepressor-induced organization and assembly of the biotin repressor: A model for allosteric activation of a transcriptional regulator
Larry H. Weaver, Keehwan Kwon, Dorothy Beckett, and Brian W. Matthews
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6045–6050. Published online 2001 May 15. doi: 10.1073/pnas.111128198.
PMCID: PMC33419
Solution structure of DFF40 and DFF45 N-terminal domain complex and mutual chaperone activity of DFF40 and DFF45
Pei Zhou, Alexey A. Lugovskoy, John S. McCarty, Peng Li, and Gerhard Wagner
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6051–6055. doi: 10.1073/pnas.111145098.
PMCID: PMC33420
Structure of sortase, the transpeptidase that anchors proteins to the cell wall of Staphylococcus aureus
Udayar Ilangovan, Hung Ton-That, Junji Iwahara, Olaf Schneewind, and Robert T. Clubb
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6056–6061. doi: 10.1073/pnas.101064198.
PMCID: PMC33421
Catalytic efficiency and vitality of HIV-1 proteases from African viral subtypes
Adrian Velazquez-Campoy, Matthew J. Todd, Sonia Vega, and Ernesto Freire
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6062–6067. Published online 2001 May 15. doi: 10.1073/pnas.111152698.
PMCID: PMC33422
Arg-302 facilitates deprotonation of Glu-325 in the transport mechanism of the lactose permease from Escherichia coli
Miklós Sahin-Tóth and H. Ronald Kaback
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6068–6073. Published online 2001 May 15. doi: 10.1073/pnas.111139698.
PMCID: PMC33423
Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins
S. H. Ong, Y. R. Hadari, N. Gotoh, G. R. Guy, J. Schlessinger, and I. Lax
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6074–6079. Published online 2001 May 15. doi: 10.1073/pnas.111114298.
PMCID: PMC33424
Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I
Stefan Gross and Claire Moore
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6080–6085. Published online 2001 May 8. doi: 10.1073/pnas.101046598.
PMCID: PMC33425
From the Cover:
Direct DNA binding by Brca1
Tanya T. Paull, David Cortez, Blair Bowers, Stephen J. Elledge, and Martin Gellert
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6086–6091. Published online 2001 May 15. doi: 10.1073/pnas.111125998.
PMCID: PMC33426
Point mutations in a nucleoside transporter gene from Leishmania donovani confer drug resistance and alter substrate selectivity
Gayatri Vasudevan, Buddy Ullman, and Scott M. Landfear
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6092–6097. Published online 2001 May 15. doi: 10.1073/pnas.101537298.
PMCID: PMC33427
Biophysics
Top-down free-energy minimization on protein potential energy landscapes
Bruce W. Church and David Shalloway
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6098–6103. Published online 2001 May 8. doi: 10.1073/pnas.101030498.
PMCID: PMC33428
Three-dimensional reconstruction of the recombinant type 3 ryanodine receptor and localization of its amino terminus
Zheng Liu, Jing Zhang, Manjuli R. Sharma, Pin Li, S. R. Wayne Chen, and Terence Wagenknecht
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6104–6109. Published online 2001 May 15. doi: 10.1073/pnas.111382798.
PMCID: PMC33429
Diffractive optics-based heterodyne-detected four-wave mixing signals of protein motion: From “protein quakes” to ligand escape for myoglobin
Gami Dadusc, Jennifer P. Ogilvie, Peter Schulenberg, Una Marvet, and R. J. Dwayne Miller
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6110–6115. Published online 2001 May 8. doi: 10.1073/pnas.101130298.
PMCID: PMC33430
Crystal cataracts: Human genetic cataract caused by protein crystallization
Ajay Pande, Jayanti Pande, Neer Asherie, Aleksey Lomakin, Olutayo Ogun, Jonathan King, and George B. Benedek
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6116–6120. doi: 10.1073/pnas.101124798.
PMCID: PMC33431
Mechanism for nucleic acid chaperone activity of HIV-1 nucleocapsid protein revealed by single molecule stretching
Mark C. Williams, Ioulia Rouzina, Jay R. Wenner, Robert J. Gorelick, Karin Musier-Forsyth, and Victor A. Bloomfield
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6121–6126. Published online 2001 May 8. doi: 10.1073/pnas.101033198.
PMCID: PMC33432
The pKa of His-24 in the folding transition state of apomyoglobin
Marc Jamin, Bernhard Geierstanger, and Robert L. Baldwin
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6127–6131. Published online 2001 May 15. doi: 10.1073/pnas.111157998.
PMCID: PMC33433
Cell Biology
Maintenance of caspase-3 proenzyme dormancy by an intrinsic “safety catch” regulatory tripeptide
Sophie Roy, Christopher I. Bayly, Yves Gareau, Vicky M. Houtzager, Stacia Kargman, Sabina L. C. Keen, Kathleen Rowland, Isolde M. Seiden, Nancy A. Thornberry, and Donald W. Nicholson
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6132–6137. Published online 2001 May 15. doi: 10.1073/pnas.111085198.
PMCID: PMC33434
Antiviral activities of the soluble extracellular domains of type I interferon receptors
Chun-Sheng Han, Yizhen Chen, Toshihiko Ezashi, and R. Michael Roberts
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6138–6143. Published online 2001 May 8. doi: 10.1073/pnas.111139598.
PMCID: PMC33435
Drosophila phosphoinositide-dependent kinase-1 regulates apoptosis and growth via the phosphoinositide 3-kinase-dependent signaling pathway
Kyoung Sang Cho, Jun Hee Lee, Sunhong Kim, Dohoon Kim, Hyongjong Koh, Jihyun Lee, Changsoo Kim, Jaeseob Kim, and Jongkyeong Chung
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6144–6149. Published online 2001 May 8. doi: 10.1073/pnas.101596998.
PMCID: PMC33436
Mutant G protein α subunit activated by Gβγ: A model for receptor activation?
Philippe Rondard, Taroh Iiri, Supriya Srinivasan, Elaine Meng, Toshiro Fujita, and Henry R. Bourne
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6150–6155. Published online 2001 May 8. doi: 10.1073/pnas.101136198.
PMCID: PMC33437
Desmuslin, an intermediate filament protein that interacts with α-dystrobrevin and desmin
Yuji Mizuno, Terri G. Thompson, Jeffrey R. Guyon, Hart G. W. Lidov, Melissa Brosius, Michihiro Imamura, Eijiro Ozawa, Simon C. Watkins, and Louis M. Kunkel
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6156–6161. Published online 2001 May 15. doi: 10.1073/pnas.111153298.
PMCID: PMC33438
Nerve growth factor displays stimulatory effects on human skin and lung fibroblasts, demonstrating a direct role for this factor in tissue repair
Alessandra Micera, Eliana Vigneti, Dalia Pickholtz, Reuven Reich, Orit Pappo, Sergio Bonini, François Xavier Maquart, Luigi Aloe, and Francesca Levi-Schaffer
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6162–6167. Published online 2001 May 8. doi: 10.1073/pnas.101130898.
PMCID: PMC33439
Pro-apoptotic gene expression mediated by the p38 mitogen-activated protein kinase signal transduction pathway
Gerard S. De Zutter and Roger J. Davis
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6168–6173. Published online 2001 May 8. doi: 10.1073/pnas.111027698.
PMCID: PMC33440
Regulation of the p21-activated kinase (PAK) by a human Gβ-like WD-repeat protein, hPIP1
Chunzhi Xia, Wenbin Ma, Lewis Joe Stafford, Stevan Marcus, Wen-Cheng Xiong, and Mingyao Liu
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6174–6179. doi: 10.1073/pnas.101137298.
PMCID: PMC33441
Mechanical stress is communicated between different cell types to elicit matrix remodeling
M. A. Swartz, D. J. Tschumperlin, R. D. Kamm, and J. M. Drazen
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6180–6185. Published online 2001 May 15. doi: 10.1073/pnas.111133298.
PMCID: PMC33442
From the Cover:
Remodeling of the postnatal mouse testis is accompanied by dramatic changes in stem cell number and niche accessibility
Takashi Shinohara, Kyle E. Orwig, Mary R. Avarbock, and Ralph L. Brinster
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6186–6191. doi: 10.1073/pnas.111158198.
PMCID: PMC33443
RhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damage
Ai-xue Liu, George J. Cerniglia, Eric J. Bernhard, and George C. Prendergast
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6192–6197. Published online 2001 May 15. doi: 10.1073/pnas.111137198.
PMCID: PMC33444
c-Jun interacts with the corepressor TG-interacting factor (TGIF) to suppress Smad2 transcriptional activity
Marcia Pessah, Céline Prunier, Jacqueline Marais, Nathalie Ferrand, Anne Mazars, François Lallemand, Jean-Michel Gauthier, and Azeddine Atfi
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6198–6203. doi: 10.1073/pnas.101579798.
PMCID: PMC33445
Developmental Biology
CtBP-dependent activities of the short-range Giant repressor in the Drosophila embryo
Yutaka Nibu and Michael S. Levine
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6204–6208. Published online 2001 May 15. doi: 10.1073/pnas.111158298.
PMCID: PMC33446
Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation
Kevin Eggan, Hidenori Akutsu, Janet Loring, Laurie Jackson-Grusby, Martina Klemm, William M. Rideout, 3rd, Ryuzo Yanagimachi, and Rudolf Jaenisch
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6209–6214. Published online 2001 May 1. doi: 10.1073/pnas.101118898.
PMCID: PMC33447
Ecology
Biomechanics of the movable pretarsal adhesive organ in ants and bees
Walter Federle, Elizabeth L. Brainerd, Thomas A. McMahon, and Bert Hölldobler
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6215–6220. Published online 2001 May 15. doi: 10.1073/pnas.111139298.
PMCID: PMC33448
Evolution
Insect herbivory, plant defense, and early Cenozoic climate change
Peter Wilf, Conrad C. Labandeira, Kirk R. Johnson, Phyllis D. Coley, and Asher D. Cutter
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6221–6226. Published online 2001 May 15. doi: 10.1073/pnas.111069498.
PMCID: PMC33449
The evolution of coloration and toxicity in the poison frog family (Dendrobatidae)
Kyle Summers and Mark E. Clough
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6227–6232. Published online 2001 May 15. doi: 10.1073/pnas.101134898.
PMCID: PMC33450
Evolution of genome–phenome diversity under environmental stress
Eviatar Nevo
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6233–6240. doi: 10.1073/pnas.101109298.
PMCID: PMC33451
Integrated fossil and molecular data reconstruct bat echolocation
Mark S. Springer, Emma C. Teeling, Ole Madsen, Michael J. Stanhope, and Wilfried W. de Jong
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6241–6246. Published online 2001 May 15. doi: 10.1073/pnas.111551998.
PMCID: PMC33452
Removing symbiotic Wolbachia bacteria specifically inhibits oogenesis in a parasitic wasp
Franck Dedeine, Fabrice Vavre, Frédéric Fleury, Benjamin Loppin, Michael E. Hochberg, and Michel Boulétreau
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6247–6252. Published online 2001 May 15. doi: 10.1073/pnas.101304298.
PMCID: PMC33453
Negative frequency-dependent selection maintains a dramatic flower color polymorphism in the rewardless orchid Dactylorhiza sambucina (L.) Soò
Luc D. B. Gigord, Mark R. Macnair, and Ann Smithson
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6253–6255. Published online 2001 May 15. doi: 10.1073/pnas.111162598.
PMCID: PMC33454
Rapid, local adaptation of zooplankton behavior to changes in predation pressure in the absence of neutral genetic changes
C. Cousyn, L. De Meester, J. K. Colbourne, L. Brendonck, D. Verschuren, and F. Volckaert
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6256–6260. Published online 2001 May 15. doi: 10.1073/pnas.111606798.
PMCID: PMC33455
From the Cover:
Effects of sampling standardization on estimates of Phanerozoic marine diversification
J. Alroy, C. R. Marshall, R. K. Bambach, K. Bezusko, M. Foote, F. T. Fürsich, T. A. Hansen, S. M. Holland, L. C. Ivany, D. Jablonski, D. K. Jacobs, D. C. Jones, M. A. Kosnik, S. Lidgard, S. Low, A. I. Miller, P. M. Novack-Gottshall, T. D. Olszewski, M. E. Patzkowsky, D. M. Raup, K. Roy, J. J. Sepkoski, Jr., M. G. Sommers, P. J. Wagner, and A. Webber
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6261–6266. Published online 2001 May 15. doi: 10.1073/pnas.111144698.
PMCID: PMC33456
Genetics
BimD/SPO76 is at the interface of cell cycle progression, chromosome morphogenesis, and recombination
Diana van Heemst, Etta Käfer, Tricia John, Christa Heyting, Mirjam van Aalderen, and Denise Zickler
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6267–6272. Published online 2001 May 15. doi: 10.1073/pnas.081088498.
PMCID: PMC33457
Painting of fourth, a chromosome-specific protein in Drosophila
Jan Larsson, J. Don Chen, Vanya Rasheva, Åsa Rasmuson-Lestander, and Vincenzo Pirrotta
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6273–6278. Published online 2001 May 15. doi: 10.1073/pnas.111581298.
PMCID: PMC33458
Identification of multiple quantitative trait loci linked to prion disease incubation period in mice
Sarah E. Lloyd, Obia N. Onwuazor, Jonathan A. Beck, Gary Mallinson, Martin Farrall, Paul Targonski, John Collinge, and Elizabeth M. C. Fisher
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6279–6283. Published online 2001 May 15. doi: 10.1073/pnas.101130398.
PMCID: PMC33459
A DAF-1-binding protein BRA-1 is a negative regulator of DAF-7 TGF-β signaling
Kiyokazu Morita, Miho Shimizu, Hiroshi Shibuya, and Naoto Ueno
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6284–6288. Published online 2001 May 15. doi: 10.1073/pnas.111409798.
PMCID: PMC33460
Generalized transduction in Streptomyces coelicolor
Julie Burke, David Schneider, and Janet Westpheling
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6289–6294. Published online 2001 May 15. doi: 10.1073/pnas.101589398.
PMCID: PMC33461
Immunology
Developmental plasticity of CNS microglia
L. Santambrogio, S. L. Belyanskaya, F. R. Fischer, B. Cipriani, C. F. Brosnan, P. Ricciardi-Castagnoli, L. J. Stern, J. L. Strominger, and R. Riese
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6295–6300. doi: 10.1073/pnas.111152498.
PMCID: PMC33462
CD8+ T cells control the TH phenotype of MBP-reactive CD4+ T cells in EAE mice
Hong Jiang, Ned S. Braunstein, Bin Yu, Robert Winchester, and Leonard Chess
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6301–6306. Published online 2001 May 15. doi: 10.1073/pnas.101123098.
PMCID: PMC33463
T cell-specific FADD-deficient mice: FADD is required for early T cell development
Nisha H. Kabra, Chulho Kang, Lianne C. Hsing, Jianke Zhang, and Astar Winoto
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6307–6312. Published online 2001 May 15. doi: 10.1073/pnas.111158698.
PMCID: PMC33464
Measuring the diaspora for virus-specific CD8+ T cells
Dana R. Marshall, Stephen J. Turner, Gabrielle T. Belz, Suzette Wingo, Samita Andreansky, Mark Y. Sangster, Janice M. Riberdy, Tiebin Liu, Ming Tan, and Peter C. Doherty
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6313–6318. Published online 2001 May 8. doi: 10.1073/pnas.101132698.
PMCID: PMC33465
T cell activation up-regulates cyclic nucleotide phosphodiesterases 8A1 and 7A3
Natalie A. Glavas, Cari Ostenson, Jonathan B. Schaefer, Valeria Vasta, and Joseph A. Beavo
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6319–6324. doi: 10.1073/pnas.101131098.
PMCID: PMC33466
Stimulation via CD40 can substitute for CD4 T cell function in preventing reactivation of a latent herpesvirus
Sally R. Sarawar, Bong Joo Lee, Su Khoh Reiter, and Stephen P. Schoenberger
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6325–6329. Published online 2001 May 15. doi: 10.1073/pnas.101136898.
PMCID: PMC33467
Medical Sciences
A role for estrogen receptor β in the regulation of growth of the ventral prostate
Zhang Weihua, Sari Mäkelä, Leif C. Andersson, Saija Salmi, Shigehira Saji, Jeanette I. Webster, Elwood V. Jensen, Stefan Nilsson, Margaret Warner, and Jan-Åke Gustafsson
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6330–6335. doi: 10.1073/pnas.111150898.
PMCID: PMC33468
A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ
Yuichi Hashimoto, Takako Niikura, Hirohisa Tajima, Takashi Yasukawa, Haruka Sudo, Yuko Ito, Yoshiko Kita, Masaoki Kawasumi, Keisuke Kouyama, Manabu Doyu, Gen Sobue, Takashi Koide, Shoji Tsuji, Jochen Lang, Kiyoshi Kurokawa, and Ikuo Nishimoto
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6336–6341. doi: 10.1073/pnas.101133498.
PMCID: PMC33469
In vitro evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies
Giuseppe Marzio, Koen Verhoef, Monique Vink, and Ben Berkhout
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6342–6347. Published online 2001 May 15. doi: 10.1073/pnas.111031498.
PMCID: PMC33470
Frequent fusion of the JAZF1 and JJAZ1 genes in endometrial stromal tumors
Jason I. Koontz, A. Lee Soreng, Marisa Nucci, Frank C. Kuo, Patrick Pauwels, Herman van den Berghe, Paola Dal Cin, Jonathan A. Fletcher, and Jeffrey Sklar
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6348–6353. doi: 10.1073/pnas.101132598.
PMCID: PMC33471
From the Cover:
Changes in the prevalence of chronic disability in the United States black and nonblack population above age 65 from 1982 to 1999
Kenneth G. Manton and XiLiang Gu
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6354–6359. Published online 2001 May 8. doi: 10.1073/pnas.111152298.
PMCID: PMC33472
CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A
Tatiana Pushkarsky, Gabriele Zybarth, Larisa Dubrovsky, Vyacheslav Yurchenko, Hao Tang, Huiming Guo, Bryan Toole, Barbara Sherry, and Michael Bukrinsky
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6360–6365. Published online 2001 May 15. doi: 10.1073/pnas.111583198.
PMCID: PMC33473
Altered stability of pulmonary surfactant in SP-C-deficient mice
Stephan W. Glasser, Michael S. Burhans, Thomas R. Korfhagen, Cheng-Lun Na, Peter D. Sly, Gary F. Ross, Machiko Ikegami, and Jeffrey A. Whitsett
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6366–6371. Published online 2001 May 8. doi: 10.1073/pnas.101500298.
PMCID: PMC33474
From the Cover:
Glutamate antagonists limit tumor growth
Wojciech Rzeski, Lechoslaw Turski, and Chrysanthy Ikonomidou
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6372–6377. Published online 2001 May 1. doi: 10.1073/pnas.091113598.
PMCID: PMC33475
Analysis of gene expression during myc oncogene-induced lymphomagenesis in the bursa of Fabricius
Paul E. Neiman, Alanna Ruddell, Christine Jasoni, Gil Loring, Sandra Jo Thomas, Kimberly A. Brandvold, Ruey-min Lee, Joan Burnside, and Jeffrey Delrow
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6378–6383. Published online 2001 May 15. doi: 10.1073/pnas.111144898.
PMCID: PMC33476
A missense mutation of the Na+ channel αII subunit gene Nav1.2 in a patient with febrile and afebrile seizures causes channel dysfunction
Takashi Sugawara, Yuji Tsurubuchi, Kishan Lal Agarwala, Masatoshi Ito, Goryu Fukuma, Emi Mazaki-Miyazaki, Hiroshi Nagafuji, Masaharu Noda, Keiji Imoto, Kazumaru Wada, Akihisa Mitsudome, Sunao Kaneko, Mauricio Montal, Keiichi Nagata, Shinichi Hirose, and Kazuhiro Yamakawa
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6384–6389. doi: 10.1073/pnas.111065098.
PMCID: PMC33477
Leptin induces vascular permeability and synergistically stimulates angiogenesis with FGF-2 and VEGF
Renhai Cao, Ebba Brakenhielm, Claes Wahlestedt, Johan Thyberg, and Yihai Cao
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6390–6395. Published online 2001 May 8. doi: 10.1073/pnas.101564798.
PMCID: PMC33478
Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing
Tomoki Todo, Robert L. Martuza, Samuel D. Rabkin, and Paul A. Johnson
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6396–6401. Published online 2001 May 15. doi: 10.1073/pnas.101136398.
PMCID: PMC33479
Anandamide and diet: Inclusion of dietary arachidonate and docosahexaenoate leads to increased brain levels of the corresponding N-acylethanolamines in piglets
Alvin Berger, Gayle Crozier, Tiziana Bisogno, Paolo Cavaliere, Sheila Innis, and Vincenzo Di Marzo
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6402–6406. Published online 2001 May 15. doi: 10.1073/pnas.101119098.
PMCID: PMC33480
Horizontal transfer of oncogenes by uptake of apoptotic bodies
Anna Bergsmedh, Anna Szeles, Marie Henriksson, Anders Bratt, M. Judah Folkman, Anna-Lena Spetz, and Lars Holmgren
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6407–6411. Published online 2001 May 15. doi: 10.1073/pnas.101129998.
PMCID: PMC33481
Trypanosoma brucei CTP synthetase: A target for the treatment of African sleeping sickness
Anders Hofer, Dietmar Steverding, Andrei Chabes, Reto Brun, and Lars Thelander
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6412–6416. Published online 2001 May 15. doi: 10.1073/pnas.111139498.
PMCID: PMC33482
Neurobiology
Precision in mouse behavior genetics
Donald Pfaff
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 5957–5960. Published online 2001 May 8. doi: 10.1073/pnas.101128598.
PMCID: PMC33404
Cerebral energetics and the glycogen shunt: Neurochemical basis of functional imaging
Robert G. Shulman, Fahmeed Hyder, and Douglas L. Rothman
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6417–6422. Published online 2001 May 8. doi: 10.1073/pnas.101129298.
PMCID: PMC33483
Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons
Kazunobu Sawamoto, Naoyuki Nakao, Kazuto Kobayashi, Natsuki Matsushita, Hiroshi Takahashi, Koji Kakishita, Atsuyo Yamamoto, Takahito Yoshizaki, Toshio Terashima, Fujio Murakami, Toru Itakura, and Hideyuki Okano
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6423–6428. Published online 2001 May 15. doi: 10.1073/pnas.111152398.
PMCID: PMC33484
Targeted mutagenesis of Lis1 disrupts cortical development and LIS1 homodimerization
Aviv Cahana, Teresa Escamez, Richard S. Nowakowski, Nancy L. Hayes, MaiBritt Giacobini, Alexander von Holst, Orit Shmueli, Tamar Sapir, Susan K. McConnell, Wolfgang Wurst, Salvador Martinez, and Orly Reiner
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6429–6434. Published online 2001 May 8. doi: 10.1073/pnas.101122598.
PMCID: PMC33485
Overexpression of p27Kip1 lengthens the G1 phase in a mouse model that targets inducible gene expression to central nervous system progenitor cells
Takayuki Mitsuhashi, Yoko Aoki, Yaman Z. Eksioglu, Takao Takahashi, Pradeep G. Bhide, Steven A. Reeves, and Verne S. Caviness, Jr.
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6435–6440. doi: 10.1073/pnas.111051398.
PMCID: PMC33486
A dendrodendritic reciprocal synapse provides a recurrent excitatory connection in the olfactory bulb
Anne Didier, Alan Carleton, Jan G. Bjaalie, Jean-Didier Vincent, Ole Petter Ottersen, Jon Storm-Mathisen, and Pierre-Marie Lledo
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6441–6446. Published online 2001 May 15. doi: 10.1073/pnas.101126398.
PMCID: PMC33487
Refractoriness to melatonin occurs independently at multiple brain sites in Siberian hamsters
David A. Freeman and Irving Zucker
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6447–6452. Published online 2001 May 15. doi: 10.1073/pnas.111140398.
PMCID: PMC33488
Requirement of the nicotinic acetylcholine receptor β2 subunit for the anatomical and functional development of the visual system
Francesco Mattia Rossi, Tommaso Pizzorusso, Vittorio Porciatti, Lisa M. Marubio, Lamberto Maffei, and Jean-Pierre Changeux
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6453–6458. Published online 2001 May 8. doi: 10.1073/pnas.101120998.
PMCID: PMC33489
DEG/ENaC ion channels involved in sensory transduction are modulated by cold temperature
Candice C. Askwith, Christopher J. Benson, Michael J. Welsh, and Peter M. Snyder
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6459–6463. Published online 2001 May 15. doi: 10.1073/pnas.111155398.
PMCID: PMC33490
Pharmacology
Diazepam-induced changes in sleep: Role of the α1 GABAA receptor subtype
Irene Tobler, Caroline Kopp, Tom Deboer, and Uwe Rudolph
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6464–6469. Published online 2001 May 15. doi: 10.1073/pnas.111055398.
PMCID: PMC33491
Platelets modulate gastric ulcer healing: Role of endostatin and vascular endothelial growth factor release
Li Ma, Susan N. Elliott, Giuseppe Cirino, Andre Buret, Louis J. Ignarro, and John L. Wallace
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6470–6475. Published online 2001 May 15. doi: 10.1073/pnas.111150798.
PMCID: PMC33492
Fluid shear stress inhibits TNF-α activation of JNK but not ERK1/2 or p38 in human umbilical vein endothelial cells: Inhibitory crosstalk among MAPK family members
James Surapisitchat, Ryan J. Hoefen, Xinchun Pi, Masanori Yoshizumi, Chen Yan, and Bradford C. Berk
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6476–6481. Published online 2001 May 15. doi: 10.1073/pnas.101134098.
PMCID: PMC33493
Mechanism underlying bupivacaine inhibition of G protein-gated inwardly rectifying K+ channels
Wei Zhou, Christine Arrabit, Senyon Choe, and Paul A. Slesinger
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6482–6487. Published online 2001 May 15. doi: 10.1073/pnas.111447798.
PMCID: PMC33494
Physiology
Evidence in support of a four transmembrane-pore-transmembrane topology model for the Arabidopsis thaliana Na+/K+ translocating AtHKT1 protein, a member of the superfamily of K+ transporters
Yasuhiro Kato, Masao Sakaguchi, Yasuo Mori, Kumiko Saito, Tatsunosuke Nakamura, Evert P. Bakker, Yoko Sato, Shinobu Goshima, and Nobuyuki Uozumi
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6488–6493. Published online 2001 May 8. doi: 10.1073/pnas.101556598.
PMCID: PMC33495
Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity
J. T. Tansey, C. Sztalryd, J. Gruia-Gray, D. L. Roush, J. V. Zee, O. Gavrilova, M. L. Reitman, C.-X. Deng, C. Li, A. R. Kimmel, and C. Londos
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6494–6499. doi: 10.1073/pnas.101042998.
PMCID: PMC33496
Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia
Takashi Shimada, Satoru Mizutani, Takanori Muto, Takashi Yoneya, Rieko Hino, Shu Takeda, Yasuhiro Takeuchi, Toshiro Fujita, Seiji Fukumoto, and Takeyoshi Yamashita
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6500–6505. Published online 2001 May 8. doi: 10.1073/pnas.101545198.
PMCID: PMC33497
Plant Biology
Sense- and antisense-mediated gene silencing in tobacco is inhibited by the same viral suppressors and is associated with accumulation of small RNAs
Francesco Di Serio, Hanspeter Schöb, Alejandro Iglesias, Corina Tarina, Estelle Bouldoires, and Frederick Meins, Jr.
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6506–6510. Published online 2001 May 15. doi: 10.1073/pnas.111423098.
PMCID: PMC33498
Tomato Ve disease resistance genes encode cell surface-like receptors
Lawrence M. Kawchuk, John Hachey, Dermot R. Lynch, Frank Kulcsar, Gijs van Rooijen, Doug R. Waterer, Albert Robertson, Eric Kokko, Robert Byers, Ronald J. Howard, Rainer Fischer, and Dirk Prüfer
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6511–6515. Published online 2001 May 1. doi: 10.1073/pnas.091114198.
PMCID: PMC33499
An important role of an inducible RNA-dependent RNA polymerase in plant antiviral defense
Zhixin Xie, Baofang Fan, Chunhong Chen, and Zhixiang Chen
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6516–6521. Published online 2001 May 15. doi: 10.1073/pnas.111440998.
PMCID: PMC33500
Induction of male sterility in plants by metabolic engineering of the carbohydrate supply
Marc Goetz, Dietmute E. Godt, Anne Guivarc'h, Uwe Kahmann, Dominique Chriqui, and Thomas Roitsch
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6522–6527. doi: 10.1073/pnas.091097998.
PMCID: PMC33501
Social Sciences
Anthropology
Stable isotope evidence for increasing dietary breadth in the European mid-Upper Paleolithic
Michael P. Richards, Paul B. Pettitt, Mary C. Stiner, and Erik Trinkaus
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6528–6532. doi: 10.1073/pnas.111155298.
PMCID: PMC33502
Social Sciences
From the Cover:
Changes in the prevalence of chronic disability in the United States black and nonblack population above age 65 from 1982 to 1999
Kenneth G. Manton and XiLiang Gu
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6354–6359. Published online 2001 May 8. doi: 10.1073/pnas.111152298.
PMCID: PMC33472
Correction
Correction
Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6533. Published online 2001 May 15.
PMCID: PMC55959
Corrects: William C. Nierman, et al. Complete genome sequence of Caulobacter crescentus. Proc Natl Acad Sci U S A. 2001 March 27; 98(7): 4136–4141.
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