Summaries & Associations of Study Results
TR-427 Turmeric,Oleoresin (Curcumin)
Target Organs and Levels of Evidence
NTP Technical Report Number 427
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| TURMERIC, OLEORESIN (CURCUMIN) 8024-37-1 |
06/23/92 | CONDIMENT. COLOR FOR OINTMENTS. (1) | Dosed-Feed R & M: 0, .2, 1.0, AND 5.0% | T.S.I. Mason Laboratories, Inc. |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | FORESTOMACH: ULCER; HYPERPLASIA; HYPERKERATOSIS | |||
| INTESTINES: ULCER; HYPERPLASIA; INFLAMMATION | ||||
| LYMPH NODE: (MESENTERIC) SINUS ECTASIA | ||||
| FR: EQUIVOCAL EVIDENCE | CLITORAL GLAND: ADENOMA 5/50 12/48 15/47 16/49 OR CARCINOMA 1/50 4/48 0/47 0/49 COMBINED 6/50 16/48 15/47 16/49 | |||
| NON-NEOPLASTIC LESIONS: | INTESTINES: ULCER; HYPERPLASIA; INFLAMMATION | |||
| LYMPH NODE: (MESENTERIC) SINUS ECTASIA | ||||
| MM: EQUIVOCAL EVIDENCE | LIVER: ADENOMA 25/50 28/50 35/50 30/50 OR CARCINOMA 12/50 18/50 16/50 18/50 COMBINED 30/50 38/50 41/50 37/50 | |||
| INTESTINES: CARCINOMA 0/50 3/50 3/50 0/50 | ||||
| FM: EQUIVOCAL EVIDENCE | LIVER: ADENOMA 7/50 8/50 19/51 14/50 OR CARCINOMA 7/50 5/50 10/51 6/50 COMBINED 13/50 12/50 25/51 19/50 | |||
| NON-NEOPLASTIC LESIONS: | THYROID GLAND: FOLLICULAR CELL HYPERPLASIA | |||
Web page last updated on February 10, 2006
