Summaries & Associations of Study Results
TR-411 C.I. Pigment Red 23
Target Organs and Levels of Evidence
NTP Technical Report Number 411
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| C.I. PIGMENT RED 23 6471-49-4 |
03/11/91 | IN PAINT, INK, PLASTIC, RUBBER AND TEXTILE PRINTING. (TDB) | Dosed-Feed R&M: 0, 10000, 25000, 50000 PPM (60 PER GROUP) | Southern Research Institute |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: EQUIVOCAL EVIDENCE | KIDNEY TUBULAR CELL: ADENOMA 0/50 0/48 0/50 2/50 OR CARCINOMA 0/50 0/48 1/50 1/50 COMBINED 0/50 0/48 1/50 3/50 | |||
| OTHER :CONSIDERATIONS: | HEMATOPOIETIC SYSTEM: MONONUCLEAR CELL LEUKEMIA 28/50 22/50 10/50 4/50 | |||
| NON-NEOPLASTIC LESIONS: | KIDNEY: RENAL TUBULE, HYPERPLASIA; INCREASED SEVERITY OF NEPHROPATHY | |||
| FR: NO EVIDENCE | ||||
| OTHER :CONSIDERATIONS: | HEMATOPOIETIC SYSTEM: MONONUCLEAR CELL LEUKEMIA 14/50 7/50 3/50 3/50 | |||
| MM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | FORESTOMACH: HYPERKERATOSIS; EPITHELIUM, HYPERPLASIA | |||
| FM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | FORESTOMACH: HYPERKERATOSIS; EPITHELIUM, HYPERPLASIA | |||
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