Testing Status of Agents at NTP
C.I. Pigment red 23
CASRN: 6471-49-4
Formula: C24-H17-N5-O7
Synonyms/Common Names:
- 3-HYDROXY-4-((2-METHOXY-5-NITROPHENYL)AZO)-N-(3-NITROPHENYL)-2-NAPTHALENECARBOXAMIDE (9CI)
- RED 23, C.I. PIGMENT
Known Uses:
IN PAINT, INK, PLASTIC, RUBBER AND TEXTILE PRINTING. (TDB)
Short-Term Toxicity
- 14-Day (Dosed-Feed)
(C60377) Completed
- NTIS No. PB93-228435
(Peer Review 03/11/1991)
Citation: Toxicology and Carcinogenesis Studies of C.I. Pigment Red 23 (CAS No. 6471-49-4) in F344 Rats and B6C3F1 Mice (Feed Studies) - Rats: F344/N; Mice: B6C3F1
- NTIS No. PB93-228435
(Peer Review 03/11/1991)
- 13-Week (Dosed-Feed)
(C60377) Completed
- NTIS No. PB93-228435
(Peer Review 03/11/1991)
Citation: Toxicology and Carcinogenesis Studies of C.I. Pigment Red 23 (CAS No. 6471-49-4) in F344 Rats and B6C3F1 Mice (Feed Studies) - Rats: F344/N; Mice: B6C3F1
- Dose: R&M: 0, 3000, 6000, 12500, 25000, 50000 PPM (10 PER GROUP)
- NTIS No. PB93-228435
(Peer Review 03/11/1991)
Long-Term Carcinogenicity
- 2-YEAR (Dosed-Feed)
(C60377) Report Complete
- TR-411 (NTIS No. PB93-228435)
(Peer Review 03/11/1991)
Toxicology and Carcinogenesis Studies of C.I. Pigment Red 23 (CAS No. 6471-49-4) in F344 Rats and B6C3F1 Mice (Feed Studies) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Equivocal Evidence
- Female Rats No Evidence
- Male Mice No Evidence
- Female Mice No Evidence
- Dose: R&M: 0, 10000, 25000, 50000 PPM (60 PER GROUP)
- TR-411 (NTIS No. PB93-228435)
(Peer Review 03/11/1991)
Special Studies
- Absorption Disposition Metabolism Elimination (Gavage)
(S0031) Completed
- Citation: EL DAREER, S.M., TILLERY, K.F. & HILL, D.L.: INVESTIGATIONS ON THE DISPOSITION OF ORAL DOSES OF SOME WATER-INSOLUBLE PIGMENTS, BULL ENVIRON CONTAM TOXICOL, 32:171-174, 1984.
- Rats
- Dose: 5.2 MG/KG
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(115073) Completed
- Chromosome Aberation Negative
- Sister Chromatid Exchange Positive
- Salmonella
(721735) Completed
- Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
- Positive
Web page last updated on January 22, 2009