Summaries & Associations of Study Results
TR-401 2,4-Diaminophenol Dihydrochloride
Target Organs and Levels of Evidence
NTP Technical Report Number 401
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| 2,4-DIAMINOPHENOL DIHYDROCHLORIDE 137-09-7 |
03/11/91 | PHOTOGRAPHIC DEVELOPER. DYEING FURS AND HAIR. ANALYTICAL REAGENT. (TDB) | Gavage R: 0,12.5,25, M: 0,19,38 MG/KG/60 PER GROUP | T.S.I. Mason Laboratories, Inc. |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | KIDNEY: RENAL TUBULE, HYPERPLASIA, FOCAL; INCREASED SEVERITY OF NEPHROPATHY | |||
| FR: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | KIDNEY: RENAL TUBULE, HYPERPLASIA, FOCAL; NEPHROPATHY | |||
| MM: SOME EVIDENCE | KIDNEY TUBULAR CELL: ADENOMA 0/50 0/48 3/50 | |||
| NON-NEOPLASTIC LESIONS: | KIDNEY: NECROSIS; RENAL TUBULE, REGENERATION; RENAL TUBULE, HYPERPLASIA; RENAL TUBULE, DILATATION | |||
| FORESTOMACH: ACANTHOSIS | ||||
| FM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | KIDNEY: NECROSIS; RENAL TUBULE, REGENERATION | |||
Web page last updated on February 10, 2006
