Summaries & Associations of Study Results
TR-393 Sodium Fluoride
Target Organs and Levels of Evidence
NTP Technical Report Number 393
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| SODIUM FLUORIDE 7681-49-4 |
04/26/90 | INSECTICIDE, ENAMELS, GLASS MIXES, STEEL DE-GASSING AGENT, ELECTROPLATING FLUXES, FLUORIDATION OF DRINKING WATER, DISINFECTING FERMENTATION APPARATUS, PRESERVING WOOD, PASTES, MANUF. COATED PAPER, DENTAL CARIES PROPHYLACTIC (MERCK 1989) | Dosed-Water R&M: 0,25,100,175 PPM | Battelle Columbus Laboratory |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: EQUIVOCAL EVIDENCE | BONE: OSTEOSARCOMA 0/80 0/50 1/50 3/80 | |||
| NON-NEOPLASTIC LESIONS: | TEETH: DENTINE, INCISOR, DYSPLASIA; INCISOR, AMELOBLAST, DEGENERATION; ATTRITION; DEFORMITY; DISCOLORATION | |||
| FR: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | TEETH: DENTINE, INCISOR, DYSPLASIA; INCISOR, AMELOBLAST, DEGENERATION;ATTRITION; DEFORMITY; DISCOLORATION | |||
| BONE: OSTEOSCLEROSIS | ||||
| MM: NO EVIDENCE | ||||
| FM: NO EVIDENCE | ||||
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