Summaries & Associations of Study Results
TR-361 Hexachloroethane
Target Organs and Levels of Evidence
NTP Technical Report Number 361
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| HEXACHLOROETHANE 67-72-1 |
10/03/88 | SOLVENT, IN EXPLOSIVES, CAMPHOR SUBSTITUTE IN CELLULOID, IN PRODUCTION OF METALS, ANTIHELMINTIC DRUG, MOTH REPELLANT, RUBBER VULCANIZING, FLAME PROOFING (HSDB 1990) | Gavage MR: 0, 10, 20, FR: 0, 80, 160 MG/KG/50 PER GROUP | T.S.I. Mason Laboratories, Inc. |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: CLEAR EVIDENCE | KIDNEY TUBULAR CELL: ADENOMA 1/50 2/50 3/50 OR CARCINOMA 0/50 0/50 3/50 COMBINED 1/50 2/50 7/50 | |||
| KIDNEY TUBULAR CELL: ADENOMA 0/50 0/50 1/50 | ||||
| MAY HAVE BEEN RELATED: | ADRENAL GLAND MEDULLA: PHEOCHROMOCYTOMA 15/50 28/45 21/49 | |||
| NON-NEOPLASTIC LESIONS: | KIDNEY: INCREASED SEVERITY OF NEPHROPATHY; MINERALIZATION 2/50 15/50 32/50; PELVIS, TRANSITIONAL EPITHELIUM, HYPERPLASIA 0/50 7/50 7/50 | |||
| FR: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | KIDNEY: INCREASED SEVERITY OF NEPHROPATHY; NEPHROPATHY 22/50 42/50 45/50 | |||
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