Summaries & Associations of Study Results
TR-000 Chlordecone (Kepone) & Choloroform
Target Organs and Levels of Evidence
NTP Technical Report Number 000
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| CHLORDECONE (KEPONE) 143-50-0 |
INSECTICIDE FOR FRUIT TREES; AS A FUNGICIDE; BASE MATERIAL FOR THE MANUFACTURE OF KELEVAN. | Dosed-Feed FR: 0,18,26 (AVG), MR: 0,8,24 (AVG), FM: 0,20,40 (AVG), MM: 0,20,23 (AVG) PPM | Gulf South Research Institute | |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: POSITIVE | LIVER: CARCINOMA; HYPERPLASIA | |||
| FR: POSITIVE | LIVER: CARCINOMA; HYPERPLASIA | |||
| MM: POSITIVE | LIVER: CARCINOMA; HYPERPLASIA | |||
| FM: POSITIVE | LIVER: CARCINOMA; HYPERPLASIA | |||
| CHLOROFORM 67-66-3 |
09/00/76 | CHEMICAL INTERMEDIATE FOR FLUOROCARBON 22, MILDEWCIDE FOR TOBACCO SEEDLINGS, SOIL FUMIGANT & INSECTICIDE, DRYCLEANING AGENT, CHEMICAL INTERMEDIATE FOR DYES (HSDB 1990) | Gavage MR:0,90,180 FR:0,125,250 (WK 1-22) 0,90,180 (WK23-SAC) FM:0,7,14 MM:0,4,8 MG/KG/50 PER GROUP | Hazleton (Vienna) |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: POSITIVE | KIDNEY TUBULAR CELL: ADENOMA OR ADENOCARCINOMA COMBINED | |||
| FR: NEGATIVE | ||||
| MM: POSITIVE | LIVER: CARCINOMA | |||
| FM: POSITIVE | LIVER: CARCINOMA | |||
Web page last updated on February 10, 2006
