| | Editorial The Impact Factor Game: It is time to find a better way to assess the scientific literature The PLoS Medicine Editors PMCID: PMC1475651 Essays Implementation Research Is Needed to Achieve International Health Goals David Sanders and Andy Haines PMCID: PMC1472551 The Limits of Reductionism in Medicine: Could Systems Biology Offer an Alternative? Andrew C Ahn, Muneesh Tewari, Chi-Sang Poon, and Russell S Phillips PMCID: PMC1459480 Sacred Cows and Sympathetic Squirrels: The Importance of Biological Diversity to Human Health Andy Dobson, Isabella Cattadori, Robert D Holt, Richard S Ostfeld, Felicia Keesing, Kristle Krichbaum, Jason R Rohr, Sarah E Perkins, and Peter J Hudson PMCID: PMC1472550 Neglected Diseases Confronting the Neglected Problem of Snake Bite Envenoming: The Need for a Global Partnership José María Gutiérrez, R. David G Theakston, and David A Warrell PMCID: PMC1472552 Perspectives Suicide Rates and Antidepressant Prescribing: A Casual or Causal Relationship? Bernhard Baune and Phillipa Hay PMCID: PMC1475652 Improving Prescribing Practices in Primary Care: A randomised trial and economic analysis of a multicomponent intervention showed small, but important, gains Chris Del Mar PMCID: PMC1472554 Apolipoprotein E and Coronary Disease: A Puzzling Paradox Muredach Reilly and Daniel J Rader PMCID: PMC1472555 Insights into the Physiology of Childbirth Using Transcriptomics Roberto Romero, Adi L Tarca, and Gerard Tromp PMCID: PMC1475648 Health in Action The Commission on Social Determinants of Health: Tackling the Social Roots of Health Inequities Alec Irwin, Nicole Valentine, Chris Brown, Rene Loewenson, Orielle Solar, Hilary Brown, Theadora Koller, and Jeanette Vega PMCID: PMC1459479 The Roulette Wheel: An Aid to Informed Decision Making Jerome R Hoffman, Michael S Wilkes, Frank C Day, Douglas S Bell, and Jerilyn K Higa PMCID: PMC1475654 Policy Forum Advertising in Medical Journals: Should Current Practices Change? Adriane Fugh-Berman, Karen Alladin, and Jarva Chow PMCID: PMC1450016 Pandemic Influenza: Risk of Multiple Introductions and the Need to Prepare for Them Christina E Mills, James M Robins, Carl T Bergstrom, and Marc Lipsitch PMCID: PMC1370924 Getting It Right: Being Smarter about Clinical Trials Barnett S Kramer, Joan Wilentz, Duane Alexander, John Burklow, Lawrence M Friedman, Richard Hodes, Ruth Kirschstein, Amy Patterson, Griffin Rodgers, and Stephen E Straus PMCID: PMC1435786 The National Security Implications of HIV/AIDS Harley Feldbaum, Kelley Lee, and Preeti Patel PMCID: PMC1475649 Manslaughter by Fake Artesunate in Asia—Will Africa Be Next? Paul N Newton, Rose McGready, Facundo Fernandez, Michael D Green, Manuela Sunjio, Carinne Bruneton, Souly Phanouvong, Pascal Millet, Christopher J. M Whitty, Ambrose O Talisuna, Stephane Proux, Eva Maria Christophel, Grace Malenga, Pratap Singhasivanon, Kalifa Bojang, Harparkash Kaur, Kevin Palmer, Nicholas P. J Day, Brian M Greenwood, François Nosten, and Nicholas J White PMCID: PMC1475657 Student Forum Improving Access to Medicines in Poor Countries: The Role of Universities Dave A Chokshi PMCID: PMC1435781 Case Report Mitral Stenosis Presenting with Acute Hearing Loss Chamutal Gur, Gadi Lalazar, Guy Raphaeli, Dan Gilon, and Eldad Ben-Chetrit PMCID: PMC1479417 Research Articles Rational Prescribing in Primary Care (RaPP): A Cluster Randomized Trial of a Tailored Intervention Atle Fretheim, Andrew D Oxman, Kari Håvelsrud, Shaun Treweek, Doris T Kristoffersen, and Arild Bjørndal PMCID: PMC1472695 Linkage Disequilibrium Mapping of
CHEK2: Common Variation and Breast Cancer Risk
Kristjana Einarsdóttir, Keith Humphreys, Carine Bonnard, Juni Palmgren, Mark M Iles, Arvid Sjölander, Yuqing Li, Kee Seng Chia, Edison T Liu, Per Hall, Jianjun Liu, and Sara Wedrén PMCID: PMC1457009 Labor-Associated Gene Expression in the Human Uterine Fundus, Lower Segment, and Cervix Radek Bukowski, Gary D. V Hankins, George R Saade, Garland D Anderson, and Steven Thornton PMCID: PMC1475650 ApoE Plasma Levels and Risk of Cardiovascular Mortality in Old Age Simon P Mooijaart, Jimmy F. P Berbée, Diana van Heemst, Louis M Havekes, Anton J. M de Craen, P. Eline Slagboom, Patrick C. N Rensen, and Rudi G. J Westendorp PMCID: PMC1457005 Immune Protection of Nonhuman Primates against Ebola Virus with Single Low-Dose Adenovirus Vectors Encoding Modified GPs Nancy J Sullivan, Thomas W Geisbert, Joan B Geisbert, Devon J Shedlock, Ling Xu, Laurie Lamoreaux, Jerome H. H. V Custers, Paul M Popernack, Zhi-Yong Yang, Maria G Pau, Mario Roederer, Richard A Koup, Jaap Goudsmit, Peter B Jahrling, and Gary J Nabel PMCID: PMC1459482 Deployment of Early Diagnosis and Mefloquine- Artesunate Treatment of Falciparum Malaria in Thailand: The Tak Malaria Initiative Verena Ilona Carrara, Supakit Sirilak, Janjira Thonglairuam, Chaiporn Rojanawatsirivet, Stephane Proux, Valery Gilbos, Al Brockman, Elizabeth A Ashley, Rose McGready, Srivicha Krudsood, Somjai Leemingsawat, Sornchai Looareesuwan, Pratap Singhasivanon, Nicholas White, and François Nosten PMCID: PMC1470664 Bioinformatics and Multiepitope DNA Immunization to Design Rational Snake Antivenom Simon C Wagstaff, Gavin D Laing, R. David G Theakston, Christina Papaspyridis, and Robert A Harrison PMCID: PMC1472699 Does Random Treatment Assignment Cause Harm to Research Participants? Cary P Gross, Harlan M Krumholz, Gretchen Van Wye, Ezekiel J Emanuel, and David Wendler PMCID: PMC1470665 Modeling of the Temporal Patterns of Fluoxetine Prescriptions and Suicide Rates in the United States Michael S Milane, Marc A Suchard, Ma-Li Wong, and Julio Licinio PMCID: PMC1475655 Mass Fatality Management following the South Asian Tsunami Disaster: Case Studies in Thailand, Indonesia, and Sri Lanka Oliver W Morgan, Pongruk Sribanditmongkol, Clifford Perera, Yeddi Sulasmi, Dana Van Alphen, and Egbert Sondorp PMCID: PMC1472696 Lentiviral Expression of Retinal Guanylate Cyclase-1 (RetGC1) Restores Vision in an Avian Model of Childhood Blindness Melissa L Williams, Jason E Coleman, Shannon E Haire, Tomas S Aleman, Artur V Cideciyan, Izabel Sokal, Krzysztof Palczewski, Samuel G Jacobson, and Susan L Semple-Rowland PMCID: PMC1463903 Delaying the International Spread of Pandemic Influenza Ben S Cooper, Richard J Pitman, W. John Edmunds, and Nigel J Gay PMCID: PMC1450020 Rational Prescribing in Primary Care (RaPP): Economic Evaluation of an Intervention to Improve Professional Practice Atle Fretheim, Morten Aaserud, and Andrew D Oxman PMCID: PMC1472698 Improving Imperfect Data from Health Management Information Systems in Africa Using Space–Time Geostatistics Peter W Gething, Abdisalan M Noor, Priscilla W Gikandi, Esther A. A Ogara, Simon I Hay, Mark S Nixon, Robert W Snow, and Peter M Atkinson PMCID: PMC1470663 Acute-Phase Serum Amyloid A: An Inflammatory Adipokine and Potential Link between Obesity and Its Metabolic Complications Rong-Ze Yang, Mi-Jeong Lee, Hong Hu, Toni I Pollin, Alice S Ryan, Barbara J Nicklas, Soren Snitker, Richard B Horenstein, Kristen Hull, Nelson H Goldberg, Andrew P Goldberg, Alan R Shuldiner, Susan K Fried, and Da-Wei Gong PMCID: PMC1472697 Correspondence and Other Communications Investing in Exposure Abdul Moiz Khan PMCID: PMC1481641 Hyperinfectivity in Cholera: A New Mechanism for an Old Epidemiological Model? Mercedes Pascual, Katia Koelle, and Andrew P Dobson PMCID: PMC1481642 Industry and Bioethics: What Price the Relationship? Mark Boyd and Wendy Rogers PMCID: PMC1481643 To Fully Tackle the Gang of Four, Needs-Driven R & D Is Essential Els Torreele, Catherine Royce, Robert Don, Ann-Marie Sevcsik, and Simon Croft PMCID: PMC1481644 Response from Savioli and Colleagues from the Department of Neglected Tropical Diseases, World Health Organization Lorenzo Savioli, Dirk Engels, Denis Daumerie, Jean Jannin, Jorge Alvar, Kingsley Asiedu, Marc Gastellu-Etchegorry, Pere Simarro, and Silvio P Mariotti PMCID: PMC1481645 Authors' Reply Peter J Hotez, David H Molyneux, Alan Fenwick, Eric Ottesen, Sonia Ehrlich Sachs, and Jeffrey D Sachs PMCID: PMC1481646 Author's Reply Richard L Kravitz PMCID: PMC1481647 Merck's Actions Surrounding Vioxx Michael Heinley PMCID: PMC1481648 Authors' Reply Jocelyn E Mackie, Andrew D Taylor, David L Finegold, Abdallah S Daar, and Peter A Singer PMCID: PMC1481649 |
