| | This journal provides immediate access to some articles. Commentary MED1: A central molecule for maintenance of genome integrity and response to DNA damage Barbara L. Parsons PMCID: PMC299743 Perspective Hox cluster duplications and the opportunity for evolutionary novelties Gunte P. Wagner, Chris Amemiya, and Frank Ruddle PMCID: PMC299744 Biography INAUGURAL ARTICLE by a Recently Elected Academy Member: Biography of Robert A. Lamb Christen Brownlee PMCID: PMC324431 Physical Sciences Applied Physical Sciences A microfluidic model for single-cell capillary obstruction by Plasmodium falciparum-infected erythrocytes J. Patrick Shelby, John White, Karthikeyan Ganesan, Pradipsinh K. Rathod, and Daniel T. Chiu PMCID: PMC299747 Chemistry Induced-fit recognition of DNA by organometallic complexes with dynamic stereogenic centers Haimei Chen, John A. Parkinson, Olga Nováková, Juraj Bella, Fuyi Wang, Alice Dawson, Robert Gould, Simon Parsons, Viktor Brabec, and Peter J. Sadler PMCID: PMC299748 Studies on the structure and dynamics of the human telomeric G quadruplex by single-molecule fluorescence resonance energy transfer Liming Ying, Jeremy J. Green, Haitao Li, David Klenerman, and Shankar Balasubramanian PMCID: PMC299749 From the Cover:
Segmented spiral waves in a reaction-diffusion system Vladimir K. Vanag and Irving R. Epstein PMCID: PMC299750 The molecular basis for the high photosensitivity of rhodopsin Robert S. H. Liu and Leticia U. Colmenares PMCID: PMC299751 Thermodynamic stability of hydrogen clathrates Serguei Patchkovskii and John S. Tse PMCID: PMC299752 Use of thiol-disulfide equilibria to measure the energetics of assembly of transmembrane helices in phospholipid bilayers Lidia Cristian, James D. Lear, and William F. DeGrado PMCID: PMC299801 Structures and relative free energies of partially folded states of proteins Michele Vendruscolo, Emanuele Paci, Martin Karplus, and Christopher M. Dobson PMCID: PMC299809 A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylation Howard C. Hang, Chong Yu, Darryl L. Kato, and Carolyn R. Bertozzi PMCID: PMC299823 Geology From the Cover:
Natural occurrence and synthesis of two new postspinel polymorphs of chromite Ming Chen, Jinfu Shu, Ho-kwang Mao, Xiande Xie, and Russell J. Hemley PMCID: PMC299753 Geophysics Measurements of the concentration and composition of nuclei for cirrus formation P. J. DeMott, D. J. Cziczo, A. J. Prenni, D. M. Murphy, S. M. Kreidenweis, D. S. Thomson, R. Borys, and D. C. Rogers PMCID: PMC299754 Physics A coarse-grained model for a nanometer-scale molecular pump Oded Hod and Eran Rabani PMCID: PMC299755 Statistics Detection of cancer-specific markers amid massive mass spectral data Wei Zhu, Xuena Wang, Yeming Ma, Manlong Rao, James Glimm, and John S. Kovach PMCID: PMC299756 Biological Sciences Agricultural Sciences Genetic engineering of the glyoxalase pathway in tobacco leads to enhanced salinity tolerance S. L. Singla-Pareek, M. K. Reddy, and S. K. Sopory PMCID: PMC299757 Applied Biological Sciences Cu nanocrystal growth on peptide nanotubes by biomineralization: Size control of Cu nanocrystals by tuning peptide conformation Ipsita A. Banerjee, Lingtao Yu, and Hiroshi Matsui PMCID: PMC299758 Mineralized matrix deposition by marrow stromal osteoblasts in 3D perfusion culture increases with increasing fluid shear forces Vassilios I. Sikavitsas, Gregory N. Bancroft, Heidi L. Holtorf, John A. Jansen, and Antonios G. Mikos PMCID: PMC299759 Biochemistry A peptide switch regulates DNA polymerase processivity Francisco J. López de Saro, Roxana E. Georgescu, and Mike O'Donnell PMCID: PMC299760 The RNA polymerase III transcriptome revealed by genome-wide localization and activity–occupancy relationships Douglas N. Roberts, Allen J. Stewart, Jason T. Huff, and Bradley R. Cairns PMCID: PMC299761 Crystal structure of the complete core of archaeal signal recognition particle and implications for interdomain communication Ken R. Rosendal, Klemens Wild, Guillermo Montoya, and Irmgard Sinning PMCID: PMC299766 Determination of the substrate-docking site of protein tyrosine kinase C-terminal Src kinase Sungsoo Lee, Xiaofeng Lin, Nguyen Hai Nam, Keykavous Parang, and Gongqin Sun PMCID: PMC299771 Crystal structure of human α-tocopherol transfer protein bound to its ligand: Implications for ataxia with vitamin E deficiency K. Christopher Min, Rhett A. Kovall, and Wayne A. Hendrickson PMCID: PMC299775 The thermodynamics of template-directed DNA synthesis: Base insertion and extension enthalpies Conceição A. S. A. Minetti, David P. Remeta, Holly Miller, Craig A. Gelfand, G. Eric Plum, Arthur P. Grollman, and Kenneth J. Breslauer PMCID: PMC299778 Regulation of the human GLUT4 gene promoter: Interaction between a transcriptional activator and myocyte enhancer factor 2A John B. Knight, Craig A. Eyster, Beth A. Griesel, and Ann Louise Olson PMCID: PMC299781 Catalysis and rotation of F1 motor: Cleavage of ATP at the catalytic site occurs in 1 ms before 40° substep rotation Katsuya Shimabukuro, Ryohei Yasuda, Eiro Muneyuki, Kiyotaka Y. Hara, Kazuhiko Kinosita, Jr., and Masasuke Yoshida PMCID: PMC299784 Redox regulation of surface protein thiols: Identification of integrin α-4 as a molecular target by using redox proteomics Teresa Laragione, Valentina Bonetto, Filippo Casoni, Tania Massignan, Giancarlo Bianchi, Elisabetta Gianazza, and Pietro Ghezzi PMCID: PMC299788 Interferon-stimulated transcription and innate antiviral immunity require deacetylase activity and histone deacetylase 1 Inna Nusinzon and Curt M. Horvath PMCID: PMC299790 Identification and molecular characterization of the Gα12–Rho guanine nucleotide exchange factor pathway in Caenorhabditis elegans Douglas M. Yau, Nobuhiko Yokoyama, Yoshio Goshima, Zeba K. Siddiqui, Shahid S. Siddiqui, and Tohru Kozasa PMCID: PMC299794 A pathway for the metabolism of vitamin D3: Unique hydroxylated metabolites formed during catalysis with cytochrome P450scc (CYP11A1) O. Guryev, R. A. Carvalho, S. Usanov, A. Gilep, and R. W. Estabrook PMCID: PMC299797 Lesion bypass DNA polymerases replicate across non-DNA segments Ayelet Maor-Shoshani, Vered Ben-Ari, and Zvi Livneh PMCID: PMC299799 Myeloperoxidase up-regulates the catalytic activity of inducible nitric oxide synthase by preventing nitric oxide feedback inhibition Semira Galijasevic, Ghassan M. Saed, Michael P. Diamond, and Husam M. Abu-Soud PMCID: PMC299800 Use of thiol-disulfide equilibria to measure the energetics of assembly of transmembrane helices in phospholipid bilayers Lidia Cristian, James D. Lear, and William F. DeGrado PMCID: PMC299801 Biophysics Adhesive–cohesive model for protein compressibility: An alternative perspective on stability Voichita M. Dadarlat and Carol Beth Post PMCID: PMC299802 Structure and functional significance of mechanically unfolded fibronectin type III1 intermediates Mu Gao, David Craig, Olivier Lequin, Iain D. Campbell, Viola Vogel, and Klaus Schulten PMCID: PMC299803 NMR-detected hydrogen exchange and molecular dynamics simulations provide structural insight into fibril formation of prion protein fragment 106–126 Kazuo Kuwata, Tomoharu Matumoto, Hong Cheng, Kuniaki Nagayama, Thomas L. James, and Heinrich Roder PMCID: PMC299804 Random Boolean network models and the yeast transcriptional network Stuart Kauffman, Carsten Peterson, Björn Samuelsson, and Carl Troein PMCID: PMC299805 Single-molecule studies of SNARE complex assembly reveal parallel and antiparallel configurations Keith Weninger, Mark E. Bowen, Steven Chu, and Axel T. Brunger PMCID: PMC299806 A detailed predictive model of the mammalian circadian clock Daniel B. Forger and Charles S. Peskin PMCID: PMC299807 Atomically detailed folding simulation of the B domain of staphylococcal protein A from random structures Jorge A. Vila, Daniel R. Ripoll, and Harold A. Scheraga PMCID: PMC299808 Structures and relative free energies of partially folded states of proteins Michele Vendruscolo, Emanuele Paci, Martin Karplus, and Christopher M. Dobson PMCID: PMC299809 DNA bending and unbending by MutS govern mismatch recognition and specificity Hong Wang, Yong Yang, Mark J. Schofield, Chunwei Du, Yonatan Fridman, Susan D. Lee, Erik D. Larson, James T. Drummond, Eric Alani, Peggy Hsieh, and Dorothy A. Erie PMCID: PMC299810 The tandem Src homology 2 domain of the Syk kinase: A molecular device that adapts to interphosphotyrosine distances Sangaralingam Kumaran, Richard A. Grucza, and Gabriel Waksman PMCID: PMC299811 Converting conformational changes to electrostatic energy in molecular motors: The energetics of ATP synthase Marek  trajbl, Avital Shurki, and Arieh Warshel PMCID: PMC299816 Thermodynamic treatment of oligonucleotide duplex–simplex equilibria Richard Owczarzy, Isard Dunietz, Mark A. Behlke, Irving M. Klotz, and Joseph A. Walder PMCID: PMC299820 Cell Biology INAUGURAL ARTICLE by a Recently Elected Academy Member: Influenza virus hemagglutinin concentrates in lipid raft microdomains for efficient viral fusion Makoto Takeda, George P. Leser, Charles J. Russell, and Robert A. Lamb PMCID: PMC299746 A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylation Howard C. Hang, Chong Yu, Darryl L. Kato, and Carolyn R. Bertozzi PMCID: PMC299823 Mitotic partitioning and selective reorganization of tissue-specific transcription factors in progeny cells Sayyed K. Zaidi, Daniel W. Young, Shirwin M. Pockwinse, Amjad Javed, Jane B. Lian, Janet L. Stein, Andre J. van Wijnen, and Gary S. Stein PMCID: PMC299826 Preferential megalin-mediated transcytosis of low-hormonogenic thyroglobulin: A control mechanism for thyroid hormone release Simonetta Lisi, Aldo Pinchera, Robert T. McCluskey, Thomas E. Willnow, Samuel Refetoff, Claudio Marcocci, Paolo Vitti, Francesca Menconi, Lucia Grasso, Fabiana Luchetti, A. Bernard Collins, and Michele Marinò PMCID: PMC299828 CatSper1 required for evoked Ca2+ entry and control of flagellar function in sperm Anne E. Carlson, Ruth E. Westenbroek, Timothy Quill, Dejian Ren, David E. Clapham, Bertil Hille, David L. Garbers, and Donner F. Babcock PMCID: PMC299831 Hyperactivated sperm motility driven by CatSper2 is required for fertilization Timothy A. Quill, Sarah A. Sugden, Kristen L. Rossi, Lynda K. Doolittle, Robert E. Hammer, and David L. Garbers PMCID: PMC299835 Human Mps1 protein kinase is required for centrosome duplication and normal mitotic progression Harold A. Fisk, Christopher P. Mattison, and Mark Winey PMCID: PMC299837 Distinct and nonoverlapping roles for pRB and cyclin D:cyclin-dependent kinases 4/6 activity in melanocyte survival Benjamin D. Yu, Michelle Becker-Hapak, Eric L. Snyder, Marc Vooijs, Catherine Denicourt, and Steven F. Dowdy PMCID: PMC299840 TRF3, a TATA-box-binding protein-related factor, is vertebrate-specific and widely expressed Stephan P. Persengiev, Xiaochun Zhu, Bharat L. Dixit, Glenn A. Maston, Ellen L. W. Kittler, and Michael R. Green PMCID: PMC299843 Imaging Tetrahymena ribozyme splicing activity in single live mammalian cells Sumitaka Hasegawa, W. Coyt Jackson, Roger Y. Tsien, and Jianghong Rao PMCID: PMC299846 Transmembrane phosphoprotein Cbp senses cell adhesion signaling mediated by Src family kinase in lipid rafts Takaki Shima, Shigeyuki Nada, and Masato Okada PMCID: PMC299849 Biologically active fragment of a human tRNA synthetase inhibits fluid shear stress-activated responses of endothelial cells E. Tzima, J. S. Reader, M. Irani-Tehrani, K. L. Ewalt, M. A. Schwartz, and P. Schimmel PMCID: PMC299850 Rapid Ca2+-dependent decrease of protein ubiquitination at synapses Hong Chen, Simona Polo, Pier Paolo Di Fiore, and Pietro V. De Camilli PMCID: PMC299851 Developmental Biology Differential G protein-coupled cannabinoid receptor signaling by anandamide directs blastocyst activation for implantation Haibin Wang, Hiromichi Matsumoto, Yong Guo, Bibhash C. Paria, Richard L. Roberts, and Sudhansu K. Dey PMCID: PMC299852 Notch signaling controls multiple steps of pancreatic differentiation L. Charles Murtaugh, Ben Z. Stanger, Kristen M. Kwan, and Douglas A. Melton PMCID: PMC299853 Hematopoietic progenitors express neural genes James Goolsby, Marie C. Marty, Dafna Heletz, Joshua Chiappelli, Gerti Tashko, Deborah Yarnell, Paul S. Fishman, Suhayl Dhib-Jalbut, Christopher T. Bever, Jr., Bernard Pessac, and David Trisler PMCID: PMC299854 Ecology Contrasting dynamics in the same plant–herbivore interaction M. B. Bonsall, E. van der Meijden, and M. J. Crawley PMCID: PMC299855 Buoyancy-driven flow in a peat moss layer as a mechanism for solute transport Cornelis Rappoldt, Gert-Jan J. M. Pieters, Erwin B. Adema, Gerrit J. Baaijens, Ab P. Grootjans, and Cornelis J. van Duijn PMCID: PMC299856 Experimental test of predation's effect on divergent selection during character displacement in sticklebacks Howard D. Rundle, Steven M. Vamosi, and Dolph Schluter PMCID: PMC299857 Food-web constraints on biodiversity–ecosystem functioning relationships Elisa Thébault and Michel Loreau PMCID: PMC299858 Evolution Darwinian natural selection for orange bioluminescent color in a Jamaican click beetle Uwe Stolz, Sebastian Velez, Keith V. Wood, Monika Wood, and Jeffrey L. Feder PMCID: PMC299859 Recursions for statistical multiple alignment Jotun Hein, Jens Ledet Jensen, and Christian N. S. Pedersen PMCID: PMC299860 The linear process of somatic evolution Martin A. Nowak, Franziska Michor, and Yoh Iwasa PMCID: PMC299861 Evolution of genomic diversity and sex at extreme environments: Fungal life under hypersaline Dead Sea stress Tamar Kis-Papo, Valery Kirzhner, Solomon P. Wasser, and Eviatar Nevo PMCID: PMC299862 Genetics Coding potential of laboratory and clinical strains of human cytomegalovirus Eain Murphy, Dong Yu, Jane Grimwood, Jeremy Schmutz, Mark Dickson, Michael A. Jarvis, Gabriele Hahn, Jay A. Nelson, Richard M. Myers, and Thomas E. Shenk PMCID: PMC299866 Frap, FKBP12 rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor gene Valery Bliskovsky, Edward S. Ramsay, John Scott, Wendy DuBois, Wei Shi, Shuling Zhang, Xiaolan Qian, Douglas R. Lowy, and Beverly A. Mock PMCID: PMC299869 Fragile site orthologs FHIT/FRA3B and Fhit/Fra14A2: Evolutionarily conserved but highly recombinogenic Ayumi Matsuyama, Takeshi Shiraishi, Francesco Trapasso, Tamotsu Kuroki, Hansjuerg Alder, Masaki Mori, Kay Huebner, and Carlo M. Croce PMCID: PMC299872 Chromosomal site-specific double-strand breaks are efficiently targeted for repair by oligonucleotides in yeast Francesca Storici, Christopher L. Durham, Dmitry A. Gordenin, and Michael A. Resnick PMCID: PMC299876 Site-specific recombination by the DDE family member mobile element IS30 transposase János Kiss, Mónika Szabó, and Ferenc Olasz PMCID: PMC299879 Immunology HIV-1-suppressive factors are secreted by CD4+ T cells during primary immune responses Sayed F. Abdelwahab, Fiorenza Cocchi, Kenneth C. Bagley, Roberta Kamin-Lewis, Robert C. Gallo, Anthony DeVico, and George K. Lewis PMCID: PMC299882 Natural killer cells in HIV-1 infection: Dichotomous effects of viremia on inhibitory and activating receptors and their functional correlates Domenico Mavilio, Janet Benjamin, Marybeth Daucher, Gabriella Lombardo, Shyam Kottilil, Marie A. Planta, Emanuela Marcenaro, Cristina Bottino, Lorenzo Moretta, Alessandro Moretta, and Anthony S. Fauci PMCID: PMC299884 Turning immunological memory into amnesia by depletion of dividing T cells Bertrand Bellier, Véronique Thomas-Vaslin, Marie-Françoise Saron, and David Klatzmann PMCID: PMC299887 Structural basis of peptide–carbohydrate mimicry in an antibody-combining site Nand K. Vyas, Meenakshi N. Vyas, Mary C. Chervenak, David R. Bundle, B. Mario Pinto, and Florante A. Quiocho PMCID: PMC299889 A glycopeptide in complex with MHC class I uses the GalNAc residue as an anchor Vasso Apostolopoulos, Elizabeth Yuriev, Paul A. Ramsland, Jodie Halton, Carla Osinski, Wenjun Li, Magdalena Plebanski, Hans Paulsen, and Ian F. C. McKenzie PMCID: PMC299892 Control of Bcl-2 expression by reactive oxygen species David A. Hildeman, Thomas Mitchell, Bruce Aronow, Sara Wojciechowski, John Kappler, and Philippa Marrack PMCID: PMC299895 CD24 is a genetic modifier for risk and progression of multiple sclerosis Qunmin Zhou, Kottil Rammohan, Shili Lin, Nikki Robinson, Ou Li, Xingluo Liu, Xue-feng Bai, Lijie Yin, Bruce Scarberry, Peishuang Du, Ming You, Kunliang Guan, Pan Zheng, and Yang Liu PMCID: PMC299898 IL-27 regulates IL-12 responsiveness of naïve CD4+ T cells through Stat1-dependent and -independent mechanisms Sophie Lucas, Nico Ghilardi, Ji Li, and Frédéric J. de Sauvage PMCID: PMC299900 CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly Laura Haynes, Sheri M. Eaton, Eve M. Burns, Troy D. Randall, and Susan L. Swain PMCID: PMC299903 From the Cover:
Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells Masahide Tone, Yukiko Tone, Elizabeth Adams, Stephen F. Yates, Mark R. Frewin, Stephen P. Cobbold, and Herman Waldmann PMCID: PMC299905 Medical Sciences p53 hot-spot mutants are resistant to ubiquitin-independent degradation by increased binding to NAD(P)H:quinone oxidoreductase 1 Gad Asher, Joseph Lotem, Peter Tsvetkov, Veronica Reiss, Leo Sachs, and Yosef Shaul PMCID: PMC299908 From the Cover:
The base excision repair enzyme MED1 mediates DNA damage response to antitumor drugs and is associated with mismatch repair system integrity Salvatore Cortellino, David Turner, Valeria Masciullo, Filippo Schepis, Domenico Albino, Rene Daniel, Anna Marie Skalka, Neal J. Meropol, Christophe Alberti, Lionel Larue, and Alfonso Bellacosa PMCID: PMC299910 Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor Zhenyu Yue, Shengkan Jin, Chingwen Yang, Arnold J. Levine, and Nathaniel Heintz PMCID: PMC299911 Overcoming the hypoxic barrier to radiation therapy with anaerobic bacteria Chetan Bettegowda, Long H. Dang, Ross Abrams, David L. Huso, Larry Dillehay, Ian Cheong, Nishant Agrawal, Scott Borzillary, J. Michael McCaffery, E. Latice Watson, Kuo-Shyan Lin, Fred Bunz, Kwamena Baidoo, Martin G. Pomper, Kenneth W. Kinzler, Bert Vogelstein, and Shibin Zhou PMCID: PMC299912 The atherogenic effect of excess methionine intake Aron M. Troen, Esther Lutgens, Donald E. Smith, Irwin H. Rosenberg, and Jacob Selhub PMCID: PMC299913 Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy Shulin Wang and Wafik S. El-Deiry PMCID: PMC299914 An adenoviral vector cancer vaccine that delivers a tumor-associated antigen/CD40-ligand fusion protein to dendritic cells Lixin Zhang, Yucheng Tang, Hakan Akbulut, Daniel Zelterman, Phyllis-Jean Linton, and Albert B. Deisseroth PMCID: PMC299915 Mucosal tolerance to E-selectin provides cell-mediated protection against ischemic brain injury Yong Chen, Christl Ruetzler, Sruthi Pandipati, Maria Spatz, Richard M. McCarron, Kyra Becker, and John M. Hallenbeck PMCID: PMC299916 Rapamycin is active against B-precursor leukemia in vitro and in vivo, an effect that is modulated by IL-7-mediated signaling Valerie I. Brown, Junjie Fang, Keith Alcorn, Rosalind Barr, Jenny M. Kim, Robert Wasserman, and Stephan A. Grupp PMCID: PMC299917 Amino acid substitutions in the thyroglobulin gene are associated with susceptibility to human and murine autoimmune thyroid disease Yoshiyuki Ban, David A. Greenberg, Erlinda Concepcion, Lucy Skrabanek, Ronald Villanueva, and Yaron Tomer PMCID: PMC299918 Microbiology INAUGURAL ARTICLE by a Recently Elected Academy Member: Influenza virus hemagglutinin concentrates in lipid raft microdomains for efficient viral fusion Makoto Takeda, George P. Leser, Charles J. Russell, and Robert A. Lamb PMCID: PMC299746 Activity of a type 1 picornavirus internal ribosomal entry site is determined by sequences within the 3′ nontranslated region Elena Dobrikova, Paola Florez, Shelton Bradrick, and Matthias Gromeier PMCID: PMC299919 Transfer of neutralizing IgG to macaques 6 h but not 24 h after SHIV infection confers sterilizing protection: Implications for HIV-1 vaccine development Yoshiaki Nishimura, Tatsuhiko Igarashi, Nancy L. Haigwood, Reza Sadjadpour, Olivia K. Donau, Charles Buckler, Ron J. Plishka, Alicia Buckler-White, and Malcolm A. Martin PMCID: PMC299920 Analysis of an orf virus chemokine-binding protein: Shifting ligand specificities among a family of poxvirus viroceptors Bruce T. Seet, Catherine A. McCaughan, Tracy M. Handel, Andrew Mercer, Craig Brunetti, Grant McFadden, and Stephen B. Fleming PMCID: PMC299921 Apical recycling systems regulate directional budding of respiratory syncytial virus from polarized epithelial cells Sean C. Brock, James R. Goldenring, and James E. Crowe, Jr. PMCID: PMC299925 A class of sterol 14-demethylase inhibitors as anti-Trypanosoma cruzi agents Frederick Buckner, Kohei Yokoyama, Jeffrey Lockman, Kendra Aikenhead, Junko Ohkanda, Martin Sadilek, Saïd Sebti, Wesley Van Voorhis, Andrew Hamilton, and Michael H. Gelb PMCID: PMC299928 Viral protein U counteracts a human host cell restriction that inhibits HIV-1 particle production Vasundhara Varthakavi, Rita M. Smith, Stephan P. Bour, Klaus Strebel, and Paul Spearman PMCID: PMC299932 Neuroscience Intracellular Ca2+ and the phospholipid PIP2 regulate the taste transduction ion channel TRPM5 Dan Liu and Emily R. Liman PMCID: PMC299934 TRPM5 is a transient Ca2+-activated cation channel responding to rapid changes in [Ca2+]i Dirk Prawitt, Mahealani K. Monteilh-Zoller, Lili Brixel, Christian Spangenberg, Bernhard Zabel, Andrea Fleig, and Reinhold Penner PMCID: PMC299937 Labeled cortical mantle distance maps of the cingulate quantify differences between dementia of the Alzheimer type and healthy aging M. I. Miller, M. Hosakere, A. R. Barker, C. E. Priebe, N. Lee, J. T. Ratnanather, L. Wang, M. Gado, J. C. Morris, and J. G. Csernansky PMCID: PMC299940 Cancerous stem cells can arise from pediatric brain tumors Houman D. Hemmati, Ichiro Nakano, Jorge A. Lazareff, Michael Masterman-Smith, Daniel H. Geschwind, Marianne Bronner-Fraser, and Harley I. Kornblum PMCID: PMC299944 A critical role of neural-specific JNK3 for ischemic apoptosis Chia-Yi Kuan, Alan J. Whitmarsh, Derek D. Yang, Guanghong Liao, Aryn J. Schloemer, Chen Dong, Jue Bao, Kenneth J. Banasiak, Gabriel G. Haddad, Richard A. Flavell, Roger J. Davis, and Pasko Rakic PMCID: PMC299947 Natural scene statistics as the universal basis of color context effects Fuhui Long and Dale Purves PMCID: PMC299950 Contribution of astrocytes to hippocampal long-term potentiation through release of d-serine Yunlei Yang, Wooping Ge, Yiren Chen, Zhijun Zhang, Wanhua Shen, Chienping Wu, Muming Poo, and Shumin Duan PMCID: PMC299953 The timing of phasic transmitter release is Ca2+-dependent and lacks a direct influence of presynaptic membrane potential Felix Felmy, Erwin Neher, and Ralf Schneggenburger PMCID: PMC299956 Reduction of lipocalin-type prostaglandin D synthase in the preoptic area of female mice mimics estradiol effects on arousal and sex behavior Jessica A. Mong, Nino Devidze, Andrew Goodwillie, and Donald W. Pfaff PMCID: PMC299958 Pharmacology Distinct hyperpolarizing and relaxant roles for gap junctions and endothelium-derived H2O2 in NO-independent relaxations of rabbit arteries Andrew T. Chaytor, David H. Edwards, Linda M. Bakker, and Tudor M. Griffith PMCID: PMC299961 From the Cover:
Ethanol enhances α4β3δ and α6β3δ γ-aminobutyric acid type A receptors at low concentrations known to affect humans M. Wallner, H. J. Hanchar, and R. W. Olsen PMCID: PMC299963 Interpulse growth hormone secretion in the episodic plasma profile causes the sex reversal of cytochrome P450s in senescent male rats Ravindra N. Dhir and Bernard H. Shapiro PMCID: PMC299965 Physiology Concerted regulation of skeletal muscle contractility by oxygen tension and endogenous nitric oxide Jerry P. Eu, Joshua M. Hare, Douglas T. Hess, Michel Skaf, Junhui Sun, Isabella Cardenas-Navina, Qi-An Sun, Mark Dewhirst, Gerhard Meissner, and Jonathan S. Stamler PMCID: PMC299968 The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart Juliane Stieber, Stefan Herrmann, Susanne Feil, Jana Löster, Robert Feil, Martin Biel, Franz Hofmann, and Andreas Ludwig PMCID: PMC299971 Neural correlates of the emergence of consciousness of thirst Gary Egan, Tim Silk, Frank Zamarripa, John Williams, Paolo Federico, Ross Cunnington, Leonie Carabott, John Blair-West, Robert Shade, Michael McKinley, Michael Farrell, Jack Lancaster, Graeme Jackson, Peter Fox, and Derek Denton PMCID: PMC299974 Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity Nicolas Chartrel, Cynthia Dujardin, Youssef Anouar, Jérôme Leprince, Annick Decker, Stefan Clerens, Jean-Claude Do-Régo, Frans Vandesande, Catherine Llorens-Cortes, Jean Costentin, Jean-Claude Beauvillain, and Hubert Vaudry PMCID: PMC299975 Plant Biology Map-based isolation of the leaf rust disease resistance gene Lr10 from the hexaploid wheat (Triticum aestivum L.) genome Catherine Feuillet, Silvia Travella, Nils Stein, Laurence Albar, Aurélie Nublat, and Beat Keller PMCID: PMC299976 Chlorophyll breakdown: Pheophorbide a oxygenase is a Rieske-type iron–sulfur protein, encoded by the accelerated cell death 1 gene Adriana Pružinská, Gaby Tanner, Iwona Anders, Maria Roca, and Stefan Hörtensteiner PMCID: PMC299977 Light- and pH-dependent structural changes in the PsbS subunit of photosystem II Elisabetta Bergantino, Anna Segalla, Alessia Brunetta, Enrico Teardo, Fernanda Rigoni, Giorgio Mario Giacometti, and Ildikò Szabò PMCID: PMC299978 Population Biology The population structure of Mycobacterium bovis in Great Britain: Clonal expansion Noel H. Smith, James Dale, Jacqueline Inwald, Si Palmer, Stephen V. Gordon, R. Glyn Hewinson, and John Maynard Smith PMCID: PMC299979 Evaluating plague and smallpox as historical selective pressures for the CCR5-Δ32 HIV-resistance allele Alison P. Galvani and Montgomery Slatkin PMCID: PMC299980 Psychology Expression of conditional fear with and without awareness David C. Knight, Hanh T. Nguyen, and Peter A. Bandettini PMCID: PMC299981 Corrections Proc Natl Acad Sci U S A. 2003 December 9; 100(25): 15284. Published online 2003 November 21. doi: 10.1073/pnas.2536674100.PMCID: PMC299982 Corrects: F. Archibald. Oxygen toxicity and the health and survival of eukaryote cells: A new
piece is added to the puzzle. Proc Natl Acad Sci U S A. 2003 September 2; 100(18): 10141–10143. Proc Natl Acad Sci U S A. 2003 December 9; 100(25): 15285. Published online 2003 November 21. doi: 10.1073/pnas.2637115100.PMCID: PMC299983 Corrects: Juan Martin-Serrano, et al. Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins. Proc Natl Acad Sci U S A. 2003 October 14; 100(21): 12414–12419. Proc Natl Acad Sci U S A. 2003 December 9; 100(25): 15285. Published online 2003 November 20. doi: 10.1073/pnas.2335809100.PMCID: PMC299984 Corrects: Severn B. Churn, et al. Inhibition of calcium/calmodulin kinase II alpha subunit expression results in epileptiform activity in cultured hippocampal neurons. Proc Natl Acad Sci U S A. 2000 May 9; 97(10): 5604–5609. Proc Natl Acad Sci U S A. 2003 December 9; 100(25): 15285. Published online 2003 November 25. doi: 10.1073/pnas.2436096100.PMCID: PMC299985 Corrects: Marat V. Avshalumov, et al. Activation of ATP-sensitive K+ (KATP) channels by H2O2 underlies glutamate-dependent inhibition of striatal dopamine release. Proc Natl Acad Sci U S A. 2003 September 30; 100(20): 11729–11734. |
