| | This journal provides immediate access to some articles. Commentaries Mechanisms of tumor necrosis factor α action on
neurodegeneration: Interaction with insulin-like growth factor-1 Sarah A. Loddick and Nancy J. Rothwell PMCID: PMC33706 Bacteriophages in the evolution of pathogen–host interactions Edward A. Miao and Samuel I. Miller PMCID: PMC33707 Nitric-oxide synthase and neurodegeneration/neuroprotection Paul L. Kaufman PMCID: PMC33708 Homosynaptic long-term depression: A mechanism for memory? Mark F. Bear PMCID: PMC33710 Physical Sciences Chemistry Cation-π interactions in structural biology Justin P. Gallivan and Dennis A. Dougherty PMCID: PMC22230 Striking activation of oxidative enzymes suspended in
nonaqueous media Lizhong Dai and Alexander M. Klibanov PMCID: PMC22233 The speed limit for protein folding measured by triplet–triplet energy transfer Oliver Bieri, Jakob Wirz, Bruno Hellrung, Mike Schutkowski, Mario Drewello, and Thomas Kiefhaber PMCID: PMC22254 Physics Aeolotopic interactions of globular proteins Aleksey Lomakin, Neer Asherie, and George B. Benedek PMCID: PMC22231 Biological Sciences Applied Biological Sciences Cross-linked protein crystals for vaccine delivery Nancy St. Clair, Bhami Shenoy, Lawrence D. Jacob, and Alexey L. Margolin PMCID: PMC22232 Striking activation of oxidative enzymes suspended in
nonaqueous media Lizhong Dai and Alexander M. Klibanov PMCID: PMC22233 Biochemistry Cation-π interactions in structural biology Justin P. Gallivan and Dennis A. Dougherty PMCID: PMC22230 The crystal structure of anthranilate synthase from Sulfolobus solfataricus: Functional implications Thorsten Knöchel, Andreas Ivens, Gerko Hester, Ana Gonzalez, Ronald Bauerle, Matthias Wilmanns, Kasper Kirschner, and Johan N. Jansonius PMCID: PMC22234 Steroid receptor coactivator-1 (SRC-1) enhances ligand-dependent and receptor-dependent cell-free transcription of chromatin Zheng Liu, Jiemin Wong, Sophia Y. Tsai, Ming-Jer Tsai, and Bert W. O’Malley PMCID: PMC22235 Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation Ying Li, Vesselin Mitaxov, and Gabriel Waksman PMCID: PMC22236 Selection for improved subtiligases by phage display Shane Atwell and James A. Wells PMCID: PMC22237 Phosphorylated tau can promote tubulin assembly Huang-Chun Tseng, Quan Lu, Eric Henderson, and Donald J. Graves PMCID: PMC22238 Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis Haruo Ikeda, Tomoko Nonomiya, Masayo Usami, Toshio Ohta, and Satoshi Ōmura PMCID: PMC22239 The C-terminal region of Schizosaccaromyces pombe proliferating cell nuclear antigen is essential for DNA polymerase activity Zvi Kelman, Shaojun Zuo, Martha P. Arroyo, Teresa S.-F. Wang, and Jerard Hurwitz PMCID: PMC22240 Structure-based design of an RNA-binding zinc finger Damian J. McColl, Cynthia D. Honchell, and Alan D. Frankel PMCID: PMC22241 The accessory subunit of mtDNA polymerase shares structural homology with aminoacyl-tRNA synthetases: Implications for a dual role as a primer recognition factor and processivity clamp Li Fan, Paul C. Sanschagrin, Laurie S. Kaguni, and Leslie A. Kuhn PMCID: PMC22242 Studying interactions of four proteins in the yeast two-hybrid system: Structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein Arnim Pause, Brett Peterson, Gregor Schaffar, Robert Stearman, and Richard D. Klausner PMCID: PMC22243 Rapid GTP binding and hydrolysis by Gq promoted by receptor and GTPase-activating proteins Suchetana Mukhopadhyay and Elliott M. Ross PMCID: PMC22244 Folding of a large ribozyme during transcription and the effect of the elongation factor NusA Tao Pan, Irina Artsimovitch, Xing-wang Fang, Robert Landick, and Tobin R. Sosnick PMCID: PMC22245 Regions on adenylyl cyclase that are necessary for inhibition of
activity by βγ and Giα subunits of heterotrimeric
G proteins Claus Wittpoth, Klaus Scholich, Yinges Yigzaw, Teresa M. Stringfield, and Tarun B. Patel PMCID: PMC22246 Regulation of the Src family tyrosine kinase Blk through E6AP-mediated ubiquitination Hideaki Oda, Sushant Kumar, and Peter M. Howley PMCID: PMC22247 Receptor-mediated uptake of an extracellular Bcl-xL fusion protein inhibits apoptosis Xiu-Huai Liu, JoAnn C. Castelli, and Richard J. Youle PMCID: PMC22248 Dimerization of zinc fingers mediated by peptides evolved in vitro from random sequences Bryan S. Wang and Carl O. Pabo PMCID: PMC22249 A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor Alison R. Meloni, Eric J. Smith, and Joseph R. Nevins PMCID: PMC22250 The Tyr-265-to-Cys mutator mutant of DNA polymerase β induces a mutator phenotype in mouse LN12 cells Caroline A. Clairmont, Latha Narayanan, Ka-Wai Sun, Peter M. Glazer, and Joann B. Sweasy PMCID: PMC22251 Thiostrepton inhibits the turnover but not the GTPase of elongation factor G on the ribosome Marina V. Rodnina, Andreas Savelsbergh, Natalia B. Matassova, Vladimir I. Katunin, Yuri P. Semenkov, and Wolfgang Wintermeyer PMCID: PMC22252 Biophysics Redox-linked transient deprotonation at the binuclear site in the aa3-type quinol oxidase from Acidianus ambivalens: Implications for proton translocation Tapan Kanti Das, Cláudio M. Gomes, Miguel Teixeira, and Denis L. Rousseau PMCID: PMC22253 The speed limit for protein folding measured by triplet–triplet energy transfer Oliver Bieri, Jakob Wirz, Bruno Hellrung, Mike Schutkowski, Mario Drewello, and Thomas Kiefhaber PMCID: PMC22254 Imaging of thermal activation of actomyosin motors Hirokazu Kato, Takayuki Nishizaka, Takashi Iga, Kazuhiko Kinosita, Jr., and Shin’ichi Ishiwata PMCID: PMC22255 The 3D NOESY-[1H,15N,1H]-ZQ-TROSY NMR experiment with diagonal peak suppression Konstantin V. Pervushin, Gerhard Wider, Roland Riek, and Kurt Wüthrich PMCID: PMC22256 Binding of buried structural water increases the flexibility of proteins Stefan Fischer and Chandra S. Verma PMCID: PMC22257 Protein design is a key factor for subunit–subunit association Cecilia Clementi, Paolo Carloni, and Amos Maritan PMCID: PMC22258 Cell Biology The direction of transport through the nuclear pore can be inverted Maxence V. Nachury and Karsten Weis PMCID: PMC22259 Basonuclin, a zinc finger protein of keratinocytes and reproductive germ cells, binds to the rRNA gene promoter Shiro Iuchi and Howard Green PMCID: PMC22260 Follicle cell proteasome activity and acid extract from the egg vitelline coat prompt the onset of self-sterility in Ciona intestinalis oocytes Rita Marino, Rosaria De Santis, Paola Giuliano, and Maria Rosaria Pinto PMCID: PMC22261 Immortalization of primary human keratinocytes by the helix–loop–helix protein, Id-1 Rhoda M. Alani, Jens Hasskarl, Miranda Grace, Maria-Clementia Hernandez, Mark A. Israel, and Karl Münger PMCID: PMC22262 Identification and characterization of a negative regulator of FtsZ ring formation in Bacillus subtilis Petra Anne Levin, Iren G. Kurtser, and Alan D. Grossman PMCID: PMC22263 Wiskott-Aldrich syndrome protein regulates podosomes in primary human macrophages Stefan Linder, David Nelson, Michael Weiss, and Martin Aepfelbacher PMCID: PMC22264 Integrin αIIb promoter-targeted expression of gene products in megakaryocytes derived from retrovirus-transduced human hematopoietic cells David A. Wilcox, John C. Olsen, Lori Ishizawa, Michael Griffith, and Gilbert C. White, II PMCID: PMC22265 Human eosinophils regulate human lung- and skin-derived fibroblast properties in vitro: A role for transforming growth factor β (TGF-β) Francesca Levi-Schaffer, Ekaterina Garbuzenko, Ann Rubin, Reuven Reich, Dalia Pickholz, Philippe Gillery, Herve Emonard, Arnon Nagler, and Francois A. Xavier Maquart PMCID: PMC22266 Myosin-dependent contractile activity of the actin cytoskeleton modulates the spatial organization of cell–cell contacts in cultured epitheliocytes M. Krendel, N. A. Gloushankova, E. M. Bonder, H. H. Feder, J. M. Vasiliev, and I. M. Gelfand PMCID: PMC22267 c-fos-induced growth factor/vascular endothelial growth factor D induces angiogenesis in vivo and in vitro Lucia Marconcini, Serena Marchiò, Lucia Morbidelli, Elena Cartocci, Adriana Albini, Marina Ziche, Federico Bussolino, and Salvatore Oliviero PMCID: PMC22268 Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction Cai Li and Jeffrey M. Friedman PMCID: PMC22269 Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1 Kohji Moriishi, David C. S. Huang, Suzanne Cory, and Jerry M. Adams PMCID: PMC22270 Mechanism for elimination of a tumor suppressor: Aberrant splicing of a brain-specific exon causes loss of function of Bin1 in melanoma Kai Ge, James DuHadaway, Wei Du, Meenhard Herlyn, Ulrich Rodeck, and George C. Prendergast PMCID: PMC22271 Developmental Biology The mouse bagpipe gene controls development of axial skeleton, skull, and spleen Laura A. Lettice, Lorna A. Purdie, Geoffrey J. Carlson, Fiona Kilanowski, Julia Dorin, and Robert E. Hill PMCID: PMC22272 Ecology Phenological changes reflect climate change in Wisconsin Nina L. Bradley, A. Carl Leopold, John Ross, and Wellington Huffaker PMCID: PMC22273 Spray aiming in the bombardier beetle: Photographic evidence Thomas Eisner and Daniel J. Aneshansley PMCID: PMC22274 Evolution Fifty-million-year-old polymorphism at an immunoglobulin variable region gene locus in the rabbit evolutionary lineage Chen Su and Masatoshi Nei PMCID: PMC22275 Neutral evolution of mutational robustness Erik van Nimwegen, James P. Crutchfield, and Martijn Huynen PMCID: PMC22276 Systematic changes in gene expression patterns following adaptive evolution in yeast Tracy L. Ferea, David Botstein, Patrick O. Brown, and R. Frank Rosenzweig PMCID: PMC22277 Genetics Expression pattern of the mouse ortholog of the Pendred’s syndrome gene (Pds) suggests a key role for pendrin in the inner ear Lorraine A. Everett, Hakim Morsli, Doris K. Wu, and Eric D. Green PMCID: PMC22278 Enhancer competition between H19 and Igf2 does not mediate their imprinting Jennifer V. Schmidt, John M. Levorse, and Shirley M. Tilghman PMCID: PMC22279 Sequence-tagged connectors: A sequence approach to mapping and scanning the human genome Gregory G. Mahairas, James C. Wallace, Kim Smith, Steven Swartzell, Ted Holzman, Andrew Keller, Ron Shaker, Jeff Furlong, Janet Young, Shaying Zhao, Mark D. Adams, and Leroy Hood PMCID: PMC22280 Radiation hybrid mapping of the zebrafish genome Neil A. Hukriede, Lucille Joly, Michael Tsang, Jennifer Miles, Patricia Tellis, Jonathan A. Epstein, William B. Barbazuk, Frank N. Li, Barry Paw, John H. Postlethwait, Thomas J. Hudson, Leonard I. Zon, John D. McPherson, Mario Chevrette, Igor B. Dawid, Stephen L. Johnson, and Marc Ekker PMCID: PMC22281 Two major forms of DNA (cytosine-5) methyltransferase in human somatic tissues Duen-Wei Hsu, Meng-Jau Lin, Tai-Lin Lee, Shau-Ching Wen, Xin Chen, and C.-K. James Shen PMCID: PMC22282 Regulation of endonuclease activity by proteolysis prevents breakage of unmodified bacterial chromosomes by type I restriction enzymes Svetlana Makovets, Victoria A. Doronina, and Noreen E. Murray PMCID: PMC22283 Immunology Ligation of the CD4 receptor induces activation-independent down-regulation of l-selectin Susanne Marschner, Benjamin A. Freiberg, Abraham Kupfer, Thomas Hünig, and Terri H. Finkel PMCID: PMC22284 T cell ignorance in mice to Borna disease virus can be overcome by peripheral expression of the viral nucleoprotein Jürgen Hausmann, Wiebke Hallensleben, Juan Carlos de la Torre, Axel Pagenstecher, Christine Zimmermann, Hanspeter Pircher, and Peter Staeheli PMCID: PMC22285 SLAP, a dimeric adapter protein, plays a functional role in T cell receptor signaling Jie Tang, Sansana Sawasdikosol, Jin-Hong Chang, and Steven J. Burakoff PMCID: PMC22286 An inverse relationship between T cell receptor affinity and antigen dose during CD4+ T cell responses in vivo and in vitro William Rees, Jeremy Bender, T. Kent Teague, Ross M. Kedl, Frances Crawford, Philippa Marrack, and John Kappler PMCID: PMC22287 A central role for thymic emigrants in peripheral T cell homeostasis S. P. Berzins, D. I. Godfrey, J. F. A. P. Miller, and R. L. Boyd PMCID: PMC22288 Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells Alexander B. H. Bakker, Elizabeth Baker, Grant R. Sutherland, Joseph H. Phillips, and Lewis L. Lanier PMCID: PMC22289 Functional characterization of B lymphocytes generated in vitro from embryonic stem cells Sarah K. Cho, Travis D. Webber, James R. Carlyle, Toru Nakano, Susanna M. Lewis, and Juan Carlos Zúñiga-Pflücker PMCID: PMC22290 Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation Hiroyasu Nakano, Sachiko Sakon, Haruhiko Koseki, Toshitada Takemori, Kurisu Tada, Mitsuru Matsumoto, Eiko Munechika, Tsuyoshi Sakai, Takuji Shirasawa, Hisaya Akiba, Tetsuji Kobata, Sybil M. Santee, Carl F. Ware, Paul D. Rennert, Masaru Taniguchi, Hideo Yagita, and Ko Okumura PMCID: PMC22291 Medical Sciences TCL1 oncogene expression in AIDS-related lymphomas and lymphoid tissues Michael Teitell, Michael A. Damore, Girija G. Sulur, Devin E. Turner, Marc-Henri Stern, Jonathan W. Said, Christopher T. Denny, and Randolph Wall PMCID: PMC22292 Vascular endothelial–cadherin is an important determinant of microvascular integrity in vivo Monica Corada, Massimo Mariotti, Gavin Thurston, Kelly Smith, Robin Kunkel, Manfred Brockhaus, Maria Grazia Lampugnani, Ines Martin-Padura, Antonella Stoppacciaro, Luigi Ruco, Donald M. McDonald, Peter A. Ward, and Elisabetta Dejana PMCID: PMC22293 Noninvasive quantitation of cytosine deaminase transgene expression in human tumor xenografts with in vivo magnetic resonance spectroscopy Lauren D. Stegman, Alnawaz Rehemtulla, Bradley Beattie, Els Kievit, Theodore S. Lawrence, Ronald G. Blasberg, Juri G. Tjuvajev, and Brian D. Ross PMCID: PMC22294 Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion Matthew R. Young, Jian-Jian Li, Mercedes Rincón, Richard A. Flavell, B. K. Sathyanarayana, Rosemarie Hunziker, and Nancy Colburn PMCID: PMC22295 Microbiology A molecular sensor that allows a gut commensal to control its nutrient foundation in a competitive ecosystem Lora V. Hooper, Jian Xu, Per G. Falk, Tore Midtvedt, and Jeffrey I. Gordon PMCID: PMC22296 Cytomegalovirus encodes a potent α chemokine Mark E. T. Penfold, Daniel J. Dairaghi, Gregory M. Duke, Noah Saederup, Edward S. Mocarski, George W. Kemble, and Thomas J. Schall PMCID: PMC22297 Isolation of a temperate bacteriophage encoding the type III effector protein SopE from an epidemic Salmonella typhimurium strain Susanne Mirold, Wolfgang Rabsch, Manfred Rohde, Silke Stender, Helmut Tschäpe, Holger Rüssmann, Emeka Igwe, and Wolf-Dietrich Hardt PMCID: PMC22298 Role of the Hrp type III protein secretion system in growth of Pseudomonas syringae pv. syringae B728a on host plants in the field Susan S. Hirano, Amy O. Charkowski, Alan Collmer, David K. Willis, and Christen D. Upper PMCID: PMC22299 A 21-kDa surface protein of Mycobacterium leprae binds peripheral nerve laminin-2 and mediates Schwann cell invasion Yoshihiro Shimoji, Vincent Ng, Kiichiro Matsumura, Vincent A. Fischetti, and Anura Rambukkana PMCID: PMC22300 Flagellar determinants of bacterial sensitivity to χ-phage Aravinthan D. T. Samuel, Thomas P. Pitta, William S. Ryu, Paul N. Danese, Edward C. W. Leung, and Howard C. Berg PMCID: PMC22301 Retroviral vectors preloaded with a viral receptor-ligand bridge protein are targeted to specific cell types Adrienne L. Boerger, Sophie Snitkovsky, and John A. T. Young PMCID: PMC22302 Neurobiology CoREST: A functional corepressor required for regulation of neural-specific gene expression María E. Andrés, Corinna Burger, María J. Peral-Rubio, Elena Battaglioli, Mary E. Anderson, Julia Grimes, Julia Dallman, Nurit Ballas, and Gail Mandel PMCID: PMC22303 A new mechanism of neurodegeneration: A proinflammatory cytokine inhibits receptor signaling by a survival peptide Homer D. Venters, Qingsong Tang, Qiang Liu, Roger W. VanHoy, Robert Dantzer, and Keith W. Kelley PMCID: PMC22304 Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems Wado Akamatsu, Hirotaka J. Okano, Noriko Osumi, Takayoshi Inoue, Shun Nakamura, Shin-Ichi Sakakibara, Masayuki Miura, Nobutake Matsuo, Robert B. Darnell, and Hideyuki Okano PMCID: PMC22305 θ, a novel γ-aminobutyric acid type A receptor subunit Timothy P. Bonnert, Ruth M. McKernan, Sophie Farrar, Béatrice le Bourdellès, Robert P. Heavens, David W. Smith, Louise Hewson, Michael R. Rigby, Dalip J. S. Sirinathsinghji, Nicola Brown, Keith A. Wafford, and Paul J. Whiting PMCID: PMC22306 EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology Yongqi Rong, Susan R. Doctrow, Georges Tocco, and Michel Baudry PMCID: PMC22307 Blocking taste receptor activation of gustducin inhibits gustatory responses to bitter compounds Ding Ming, Yuzo Ninomiya, and Robert F. Margolskee PMCID: PMC22308 Modulation of the intracellular calcium concentration in photoreceptor terminals by a presynaptic metabotropic glutamate receptor Peter Koulen, Rainer Kuhn, Heinz Wässle, and Johann Helmut Brandstätter PMCID: PMC22309 Loss of the ataxia–telangiectasia gene product causes oxidative damage in target organs Carrolee Barlow, Phyllis A. Dennery, Mark K. Shigenaga, Mark A. Smith, Jason D. Morrow, L. Jackson Roberts, II, Anthony Wynshaw-Boris, and Rodney L. Levine PMCID: PMC22310 Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retina Jean Bennett, Albert M. Maguire, Artur V. Cideciyan, Michael Schnell, Ernest Glover, Vibha Anand, Tomas S. Aleman, Narendra Chirmule, Abha R. Gupta, Yijun Huang, Guang-Ping Gao, William C. Nyberg, John Tazelaar, Joseph Hughes, James M. Wilson, and Samuel G. Jacobson PMCID: PMC22311 Cytoplasmic amino and carboxyl domains form a wide intracellular vestibule in an inwardly rectifying potassium channel Tao Lu, Yong-gang Zhu, and Jian Yang PMCID: PMC22312 Synaptically released glutamate reduces γ-aminobutyric acid (GABA)ergic inhibition in the hippocampus via kainate receptors Ming-Yuan Min, Zare Melyan, and Dimitri M. Kullmann PMCID: PMC22313 Decoding photoperiodic time through Per1 and ICER gene amplitude Sophie Messager, Alexander W. Ross, Perry Barrett, and Peter J. Morgan PMCID: PMC22314 Pharmacology Inhibition of nitric-oxide synthase 2 by aminoguanidine provides neuroprotection of retinal ganglion cells in a rat model of chronic glaucoma Arthur H. Neufeld, Akira Sawada, and Bernard Becker PMCID: PMC22315 Physiology Na+-H+ exchange in salivary secretory cells is controlled by an intracellular Na+ receptor H. Ishibashi, A. Dinudom, K. F. Harvey, S. Kumar, J. A. Young, and D. I. Cook PMCID: PMC22316 Plant Biology Protochlorophyllide oxidoreductase B-catalyzed protochlorophyllide photoreduction in vitro: Insight into the mechanism of chlorophyll formation in light-adapted plants Nikolai Lebedev and Michael P. Timko PMCID: PMC22317 Mapping the molecular determinant of pathogenicity in a hammerhead viroid: A tetraloop within the in vivo branched RNA conformation Marcos De la Peña, Beatriz Navarro, and Ricardo Flores PMCID: PMC22318 Corrections Proc Natl Acad Sci U S A. 1999 August 17; 96(17): 9966. PMCID: PMC56140 Corrects: Ramaswamy Chandrashekar, et al. An ERp60-like protein from the filarial parasite Dirofilaria immitis has both transglutaminase and protein disulfide isomeraseactivity. Proc Natl Acad Sci U S A. 1998 January 20; 95(2): 531–536. Proc Natl Acad Sci U S A. 1999 August 17; 96(17): 9966. PMCID: PMC56141 Corrects: Jonas Korlach, et al. Characterization of lipid bilayer phases by confocal microscopy and fluorescence correlation spectroscopy. Proc Natl Acad Sci U S A. 1999 July 20; 96(15): 8461–8466. Proc Natl Acad Sci U S A. 1999 August 17; 96(17): 9966. PMCID: PMC56142 Corrects: Maria Rescigno, et al. Bacteria-induced neo-biosynthesis, stabilization, and surface expression of functional class I molecules in mouse dendritic cells. Proc Natl Acad Sci U S A. 1998 April 28; 95(9): 5229–5234. Proc Natl Acad Sci U S A. 1999 August 17; 96(17): 9966. PMCID: PMC56143 Corrects: Timothy D. Warner, et al. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis. Proc Natl Acad Sci U S A. 1999 June 22; 96(13): 7563–7568. |
