| | This journal provides immediate access to some articles. Commentaries The galvanization of β-amyloid in Alzheimer's disease Ashley I. Bush and Rudolph E. Tanzi Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7317–7319. doi: 10.1073/pnas.122249699.PMCID: PMC124227 Activating calcium release through inositol 1,4,5-trisphosphate receptors without inositol 1,4,5-trisphosphate Martin D. Bootman, Michael J. Berridge, and H. Llewelyn Roderick Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7320–7322. doi: 10.1073/pnas.132254299.PMCID: PMC124228 Physical Sciences Applied Mathematics Probabilistic clustering of sequences: Inferring new bacterial regulons by comparative genomics Erik van Nimwegen, Mihaela Zavolan, Nikolaus Rajewsky, and Eric D. Siggia Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7323–7328. Published online 2002 May 21. doi: 10.1073/pnas.112690399.PMCID: PMC124229 Fast-phase space computation of multiple arrivals S. Fomel and J. A. Sethian Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7329–7334. doi: 10.1073/pnas.102476599.PMCID: PMC124230 A dynamic programming algorithm for haplotype block partitioning Kui Zhang, Minghua Deng, Ting Chen, Michael S. Waterman, and Fengzhu Sun Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7335–7339. Published online 2002 May 21. doi: 10.1073/pnas.102186799.PMCID: PMC124231 Chemistry Nitroxyl and its anion in aqueous solutions: Spin states, protic equilibria, and reactivities toward oxygen and nitric oxide Vladimir Shafirovich and Sergei V. Lymar Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7340–7345. Published online 2002 May 21. doi: 10.1073/pnas.112202099.PMCID: PMC124232 Engineering Sensor-independent stimulus representations David N. Levin Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7346–7351. Published online 2002 May 21. doi: 10.1073/pnas.102170499.PMCID: PMC124233 Geophysics Electric and magnetic phenomena observed before the volcano-seismic activity in 2000 in the Izu Island Region, Japan S. Uyeda, M. Hayakawa, T. Nagao, O. Molchanov, K. Hattori, Y. Orihara, K. Gotoh, Y. Akinaga, and H. Tanaka Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7352–7355. Published online 2002 May 21. doi: 10.1073/pnas.072208499.PMCID: PMC124234 Mathematics Traces, ideals, and arithmetic means Victor Kaftal and Gary Weiss Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7356–7360. Published online 2002 May 21. doi: 10.1073/pnas.112074699.PMCID: PMC124235 The structure of a class of finite ramified coverings and canonical forms of analytic matrix-functions in a neighborhood of a ramified turning point Yevsey A. Nisnevich Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7361–7366. Published online 2002 May 21. doi: 10.1073/pnas.082074899.PMCID: PMC124236 Biological Sciences Biochemistry 15-Deoxy-Δ12,14-prostaglandin J2: The endogenous electrophile that induces neuronal apoptosis Mitsuhiro Kondo, Takahiro Shibata, Takeshi Kumagai, Toshihiko Osawa, Noriyuki Shibata, Makio Kobayashi, Shoichi Sasaki, Makoto Iwata, Noriko Noguchi, and Koji Uchida Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7367–7372. Published online 2002 May 21. doi: 10.1073/pnas.112212599.PMCID: PMC124237 Long-term and homogeneous regulation of the Escherichia coli araBAD promoter by use of a lactose transporter of relaxed specificity Rachael M. Morgan-Kiss, Caryn Wadler, and John E. Cronan, Jr. Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7373–7377. Published online 2002 May 21. doi: 10.1073/pnas.122227599.PMCID: PMC124238 The crystal structure of the C-terminal fragment of striated-muscle α-tropomyosin reveals a key troponin T recognition site Yu Li, Suet Mui, Jerry H. Brown, James Strand, Ludmilla Reshetnikova, Larry S. Tobacman, and Carolyn Cohen Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7378–7383. Published online 2002 May 21. doi: 10.1073/pnas.102179999.PMCID: PMC124239 Complexation of peptidoglycan intermediates by the lipoglycodepsipeptide antibiotic ramoplanin: Minimal structural requirements for intermolecular complexation and fibril formation Predrag Cudic, James K. Kranz, Douglas C. Behenna, Ryan G. Kruger, Hellina Tadesse, A. Joshua Wand, Yuri I. Veklich, John W. Weisel, and Dewey G. McCafferty Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7384–7389. Published online 2002 May 21. doi: 10.1073/pnas.102192099.PMCID: PMC124240 Elucidation of the function of lipoprotein-sorting signals that determine membrane localization Kazuhiro Masuda, Shin-ichi Matsuyama, and Hajime Tokuda Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7390–7395. Published online 2002 May 21. doi: 10.1073/pnas.112085599.PMCID: PMC124241 Functional interactions of HslV (ClpQ) with the ATPase HslU (ClpY) Ravishankar Ramachandran, Claudia Hartmann, Hyun Kyu Song, Robert Huber, and Matthias Bochtler Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7396–7401. Published online 2002 May 21. doi: 10.1073/pnas.102188799.PMCID: PMC124242 Amyloid aggregates of the HET-s prion protein are infectious Marie-Lise Maddelein, Suzana Dos Reis, Stéphane Duvezin-Caubet, Bénédicte Coulary-Salin, and Sven J. Saupe Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7402–7407. Published online 2002 May 21. doi: 10.1073/pnas.072199199.PMCID: PMC124243 Vitamin E succinate inhibits the function of androgen receptor and the expression of prostate-specific antigen in prostate cancer cells Yu Zhang, Jing Ni, Edward M. Messing, Eugene Chang, Chin-Rang Yang, and Shuyuan Yeh Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7408–7413. doi: 10.1073/pnas.102014399.PMCID: PMC124244 Structural insight into the complex formation of latent matrix metalloproteinase 2 with tissue inhibitor of metalloproteinase 2 Ekaterina Morgunova, Ari Tuuttila, Ulrich Bergmann, and Karl Tryggvason Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7414–7419. Published online 2002 May 14. doi: 10.1073/pnas.102185399.PMCID: PMC124245 A core–BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes Mohamed-Ali Hakimi, Daniel A. Bochar, Josh Chenoweth, William S. Lane, Gail Mandel, and Ramin Shiekhattar Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7420–7425. doi: 10.1073/pnas.112008599.PMCID: PMC124246 Biophysics Binding strength and activation state of single fibrinogen-integrin pairs on living cells Rustem I. Litvinov, Henry Shuman, Joel S. Bennett, and John W. Weisel Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7426–7431. Published online 2002 May 14. doi: 10.1073/pnas.112194999.PMCID: PMC124247 Evaluating conformational free energies: The colony energy and its application to the problem of loop prediction Zhexin Xiang, Cinque S. Soto, and Barry Honig Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7432–7437. Published online 2002 May 14. doi: 10.1073/pnas.102179699.PMCID: PMC124248 Cell Biology Mutation of the Drosophila homologue of the Myb protooncogene causes genomic instability J. Robert Manak, Nesanet Mitiku, and Joseph S. Lipsick Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7438–7443. doi: 10.1073/pnas.122231599.PMCID: PMC124249 A fragment of the HMGN2 protein homes to the nuclei of tumor cells and tumor endothelial cells in vivo Kimmo Porkka, Pirjo Laakkonen, Jason A. Hoffman, Michele Bernasconi, and Erkki Ruoslahti Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7444–7449. Published online 2002 May 21. doi: 10.1073/pnas.062189599.PMCID: PMC124250 Identification of residues in TIP47 essential for Rab9 binding John Hanna, Kate Carroll, and Suzanne R. Pfeffer Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7450–7454. Published online 2002 May 21. doi: 10.1073/pnas.112198799.PMCID: PMC124251 From the Cover: Insulin-like growth factor 2 and potential regulators of hemangioma growth and involution identified by large-scale expression analysis Matthew R. Ritter, Michael I. Dorrell, Joseph Edmonds, Sheila Fallon Friedlander, and Martin Friedlander Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7455–7460. doi: 10.1073/pnas.102185799.PMCID: PMC124252 Subunit composition of mammalian transient receptor potential channels in living cells Thomas Hofmann, Michael Schaefer, Günter Schultz, and Thomas Gudermann Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7461–7466. Published online 2002 May 14. doi: 10.1073/pnas.102596199.PMCID: PMC124253 Structure and function correlation in histone H2A peptide-mediated gene transfer Danuta Balicki, Christopher D. Putnam, Puthupparampil V. Scaria, and Ernest Beutler Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7467–7471. doi: 10.1073/pnas.102168299.PMCID: PMC124254 A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway Maria A. Marchetti, Sanjay Kumar, Edgar Hartsuiker, Mohamed Maftahi, Antony M. Carr, Greg A. Freyer, William C. Burhans, and Joel A. Huberman Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7472–7477. Published online 2002 May 21. doi: 10.1073/pnas.112702399.PMCID: PMC124255 Defective lymphocyte chemotaxis in β-arrestin2- and GRK6-deficient mice Alan M. Fong, Richard T. Premont, Ricardo M. Richardson, Yen-Rei A. Yu, Robert J. Lefkowitz, and Dhavalkumar D. Patel Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7478–7483. Published online 2002 May 14. doi: 10.1073/pnas.112198299.PMCID: PMC124256 Adenoviral vectors can impair adrenocortical steroidogenesis: Clinical implications for natural infections and gene therapy Salvatore Alesci, Walter J. Ramsey, Stefan R. Bornstein, George P. Chrousos, Peter J. Hornsby, Salvatore Benvenga, Francesco Trimarchi, and Monika Ehrhart-Bornstein Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7484–7489. Published online 2002 May 21. doi: 10.1073/pnas.062170099.PMCID: PMC124257 Developmental Biology Placental overgrowth in mice lacking the imprinted gene Ipl Dale Frank, Weiwei Fortino, Lorraine Clark, Raymond Musalo, Wenxian Wang, Anjana Saxena, Chi-Ming Li, Wolf Reik, Thomas Ludwig, and Benjamin Tycko Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7490–7495. Published online 2002 May 21. doi: 10.1073/pnas.122039999.PMCID: PMC124258 ERK2 enters the nucleus by a carrier-independent mechanism Angelique W. Whitehurst, Julie L. Wilsbacher, Youngjai You, Kate Luby-Phelps, Mary Shannon Moore, and Melanie H. Cobb Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7496–7501. Published online 2002 May 21. doi: 10.1073/pnas.112495999.PMCID: PMC124259 Determining the role of patterned cell proliferation in the shape and size of the Drosophila wing Jaime Resino, Patricia Salama-Cohen, and Antonio García-Bellido Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7502–7507. Published online 2002 May 14. doi: 10.1073/pnas.072208199.PMCID: PMC124260 Evolution Estimating the age of the polydnavirus/braconid wasp symbiosis James B. Whitfield Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7508–7513. Published online 2002 May 21. doi: 10.1073/pnas.112067199.PMCID: PMC124262 Importance of compartment formation for a self-encoding system Tomoaki Matsuura, Muneyoshi Yamaguchi, Elizabeth P. Ko-Mitamura, Yasufumi Shima, Itaru Urabe, and Tetsuya Yomo Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7514–7517. Published online 2002 May 21. doi: 10.1073/pnas.062710399.PMCID: PMC124265 Genetics Probabilistic clustering of sequences: Inferring new bacterial regulons by comparative genomics Erik van Nimwegen, Mihaela Zavolan, Nikolaus Rajewsky, and Eric D. Siggia Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7323–7328. Published online 2002 May 21. doi: 10.1073/pnas.112690399.PMCID: PMC124229 From flies' eyes to our ears: Mutations in a human class III myosin cause progressive nonsyndromic hearing loss DFNB30 Tom Walsh, Vanessa Walsh, Sarah Vreugde, Ronna Hertzano, Hashem Shahin, Smadar Haika, Ming K. Lee, Moien Kanaan, Mary-Claire King, and Karen B. Avraham Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7518–7523. doi: 10.1073/pnas.102091699.PMCID: PMC124268 Restoration of spermatogenesis by lentiviral gene transfer: Offspring from infertile mice Masahito Ikawa, Vinay Tergaonkar, Atsuo Ogura, Narumi Ogonuki, Kimiko Inoue, and Inder M. Verma Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7524–7529. doi: 10.1073/pnas.072207299.PMCID: PMC124271 A rice spotted leaf gene, Spl7, encodes a heat stress transcription factor protein Utako Yamanouchi, Masahiro Yano, Hongxuan Lin, Motoyuki Ashikari, and Kyoji Yamada Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7530–7535. Published online 2002 May 14. doi: 10.1073/pnas.112209199.PMCID: PMC124274 Identification of 86 candidates for small non-messenger RNAs from the archaeon Archaeoglobus fulgidus Thean-Hock Tang, Jean-Pierre Bachellerie, Timofey Rozhdestvensky, Marie-Line Bortolin, Harald Huber, Mario Drungowski, Thorsten Elge, Jürgen Brosius, and Alexander Hüttenhofer Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7536–7541. doi: 10.1073/pnas.112047299.PMCID: PMC124276 Noncoding RNA genes identified in AT-rich hyperthermophiles Robert J. Klein, Ziva Misulovin, and Sean R. Eddy Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7542–7547. doi: 10.1073/pnas.112063799.PMCID: PMC124278 Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly Laura A. Lettice, Taizo Horikoshi, Simon J. H. Heaney, Marijke J. van Baren, Herma C. van der Linde, Guido J. Breedveld, Marijke Joosse, Nurten Akarsu, Ben A. Oostra, Naoto Endo, Minoru Shibata, Mikio Suzuki, Eiichi Takahashi, Toshikatsu Shinka, Yutaka Nakahori, Dai Ayusawa, Kazuhiko Nakabayashi, Stephen W. Scherer, Peter Heutink, Robert E. Hill, and Sumihare Noji Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7548–7553. Published online 2002 May 14. doi: 10.1073/pnas.112212199.PMCID: PMC124279 Measuring absolute expression with microarrays with a calibrated reference sample and an extended signal intensity range Aimée M. Dudley, John Aach, Martin A. Steffen, and George M. Church Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7554–7559. doi: 10.1073/pnas.112683499.PMCID: PMC124281 BRCA1 transcriptionally regulates genes involved in breast tumorigenesis Piri L. Welcsh, Ming K. Lee, Rachel M. Gonzalez-Hernandez, Daniel J. Black, Mamatha Mahadevappa, Elizabeth M. Swisher, Janet A. Warrington, and Mary-Claire King Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7560–7565. Published online 2002 May 21. doi: 10.1073/pnas.062181799.PMCID: PMC124283 Analysis of a library of macaque nuclear mitochondrial sequences confirms macaque origin of divergent sequences from old oral polio vaccine samples Jean-Pierre Vartanian and Simon Wain-Hobson Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7566–7569. Published online 2002 May 14. doi: 10.1073/pnas.112205999.PMCID: PMC124285 Immunology From the Cover: UL40-mediated NK evasion during productive infection with human cytomegalovirus Eddie C. Y. Wang, Brian McSharry, Christelle Retiere, Peter Tomasec, Sheila Williams, Leszek K. Borysiewicz, Veronique M. Braud, and Gavin W. G. Wilkinson Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7570–7575. Published online 2002 May 21. doi: 10.1073/pnas.112680099.PMCID: PMC124287 Antigen-specific and persistent tuberculin anergy in a cohort of pulmonary tuberculosis patients from rural Cambodia Julio C. Delgado, Eunice Y. Tsai, Sok Thim, Andres Baena, Vassiliki A. Boussiotis, Jean-Marc Reynes, Sun Sath, Pierre Grosjean, Edmond J. Yunis, and Anne E. Goldfeld Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7576–7581. Published online 2002 May 14. doi: 10.1073/pnas.062056099.PMCID: PMC124289 CD2 molecules redistribute to the uropod during T cell scanning: Implications for cellular activation and immune surveillance Elena V. Tibaldi, Ravi Salgia, and Ellis L. Reinherz Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7582–7587. doi: 10.1073/pnas.112212699.PMCID: PMC124291 Immunoglobulin heavy chain constant regions regulate immunity and tolerance to idiotypes of antibody variable regions Solveig Klaebo Reitan and Kristian Hannestad Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7588–7593. Published online 2002 May 14. doi: 10.1073/pnas.052150899.PMCID: PMC124293 Scavenger endothelial cells of vertebrates: A nonperipheral leukocyte system for high-capacity elimination of waste macromolecules Tore Seternes, Karen Sørensen, and Bård Smedsrød Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7594–7597. Published online 2002 May 14. doi: 10.1073/pnas.102173299.PMCID: PMC124295 Medical Sciences Symptomatic and asymptomatic benign prostatic hyperplasia: Molecular differentiation by using microarrays Kulkarni Prakash, Gregorio Pirozzi, Michael Elashoff, William Munger, Iwao Waga, Rajiv Dhir, Yoshiyuki Kakehi, and Robert H. Getzenberg Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7598–7603. Published online 2002 May 21. doi: 10.1073/pnas.112191399.PMCID: PMC124296 Synthetic LXR ligand inhibits the development of atherosclerosis in mice Sean B. Joseph, Elaine McKilligin, Liming Pei, Michael A. Watson, Alan R. Collins, Bryan A. Laffitte, Mingyi Chen, Grace Noh, Joanne Goodman, Graham N. Hagger, Jonathan Tran, Tim K. Tippin, Xuping Wang, Aldons J. Lusis, Willa A. Hsueh, Ronald E. Law, Jon L. Collins, Timothy M. Willson, and Peter Tontonoz Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7604–7609. Published online 2002 May 14. doi: 10.1073/pnas.112059299.PMCID: PMC124297 Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors Jed W. Fahey, Xavier Haristoy, Patrick M. Dolan, Thomas W. Kensler, Isabelle Scholtus, Katherine K. Stephenson, Paul Talalay, and Alain Lozniewski Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7610–7615. doi: 10.1073/pnas.112203099.PMCID: PMC124299 The phytoestrogen genistein induces thymic and immune changes: A human health concern? Srikanth Yellayi, Afia Naaz, Melissa A. Szewczykowski, Tomomi Sato, Jeffrey A. Woods, Jongsoo Chang, Mariangela Segre, Clint D. Allred, William G. Helferich, and Paul S. Cooke Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7616–7621. Published online 2002 May 21. doi: 10.1073/pnas.102650199.PMCID: PMC124301 A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9 Ajeeta B. Dash, Ifor R. Williams, Jeffery L. Kutok, Michael H. Tomasson, Ema Anastasiadou, Kathleen Lindahl, Shaoguang Li, Richard A. Van Etten, Julian Borrow, David Housman, Brian Druker, and D. Gary Gilliland Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7622–7627. doi: 10.1073/pnas.102583199.PMCID: PMC124303 Induction of the cyclic nucleotide phosphodiesterase PDE4B is essential for LPS-activated TNF-α responses S.-L. Catherine Jin and Marco Conti Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7628–7633. Published online 2002 May 21. doi: 10.1073/pnas.122041599.PMCID: PMC124305 Cyclooxygenase-2 expression is induced during human megakaryopoiesis and characterizes newly formed platelets Bianca Rocca, Paola Secchiero, Giovanni Ciabattoni, Franco O. Ranelletti, Lucia Catani, Lia Guidotti, Elisabetta Melloni, Nicola Maggiano, Giorgio Zauli, and Carlo Patrono Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7634–7639. Published online 2002 May 21. doi: 10.1073/pnas.112202999.PMCID: PMC124306 Variant-type PML-RARα fusion transcript in acute promyelocytic leukemia: Use of a cryptic coding sequence from intron 2 of the RARα gene and identification of a new clinical subtype resistant to retinoic acid therapy Bai-Wei Gu, Hui Xiong, Yan Zhou, Bing Chen, Li Wang, Shuo Dong, Zhi-Yuan Yu, Ling-Feng Lu, Ming Zhong, Hai-Feng Yin, Gen-Feng Zhu, Wei Huang, Shuang-Xi Ren, Robert E. Gallagher, Samuel Waxman, Guo-Qiang Chen, Zhu-Gang Wang, Zhu Chen, Gang Fu, and Sai-Juan Chen Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7640–7645. Published online 2002 May 21. doi: 10.1073/pnas.112194799.PMCID: PMC124308 Microbiology Insight into the molecular basis of pathogen abundance: Group A Streptococcus inhibitor of complement inhibits bacterial adherence and internalization into human cells Nancy P. Hoe, Robin M. Ireland, Frank R. DeLeo, Brian B. Gowen, David W. Dorward, Jovanka M. Voyich, Mengyao Liu, Eugene H. Burns, Jr., Derek M. Culnan, Anthony Bretscher, and James M. Musser Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7646–7651. Published online 2002 May 21. doi: 10.1073/pnas.112039899.PMCID: PMC124310 Genomewide identification of proteins secreted by the Hrp type III protein secretion system of Pseudomonas syringae pv. tomato DC3000 Tanja Petnicki-Ocwieja, David J. Schneider, Vincent C. Tam, Scott T. Chancey, Libo Shan, Yashitola Jamir, Lisa M. Schechter, Misty D. Janes, C. Robin Buell, Xiaoyan Tang, Alan Collmer, and James R. Alfano Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7652–7657. doi: 10.1073/pnas.112183899.PMCID: PMC124312 Benthic eukaryotic diversity in the Guaymas Basin hydrothermal vent environment Virginia P. Edgcomb, David T. Kysela, Andreas Teske, Alvin de Vera Gomez, and Mitchell L. Sogin Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7658–7662. Published online 2002 May 21. doi: 10.1073/pnas.062186399.PMCID: PMC124314 From the Cover: Multiple archaeal groups mediate methane oxidation in anoxic cold seep sediments Victoria J. Orphan, Christopher H. House, Kai-Uwe Hinrichs, Kevin D. McKeegan, and Edward F. DeLong Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7663–7668. Published online 2002 May 14. doi: 10.1073/pnas.072210299.PMCID: PMC124316 A therapeutic agent with oriented carbohydrates for treatment of infections by Shiga toxin-producing Escherichia coli O157:H7 Kiyotaka Nishikawa, Koji Matsuoka, Eiji Kita, Noriko Okabe, Masashi Mizuguchi, Kumiko Hino, Shinobu Miyazawa, Chisato Yamasaki, Junken Aoki, Sachio Takashima, Yoshio Yamakawa, Masahiro Nishijima, Daiyo Terunuma, Hiroyoshi Kuzuhara, and Yasuhiro Natori Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7669–7674. Published online 2002 May 21. doi: 10.1073/pnas.112058999.PMCID: PMC124317 Inorganic polyphosphate is essential for long-term survival and virulence factors in Shigella and Salmonella spp. Kwang-Seo Kim, Narayana N. Rao, Cresson D. Fraley, and Arthur Kornberg Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7675–7680. Published online 2002 May 21. doi: 10.1073/pnas.112210499.PMCID: PMC124319 Induction of natural competence in Streptococcus pneumoniae triggers lysis and DNA release from a subfraction of the cell population Hilde Steinmoen, Eivind Knutsen, and Leiv Sigve Håvarstein Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7681–7686. Published online 2002 May 14. doi: 10.1073/pnas.112464599.PMCID: PMC124321 The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA) Mark C. Enright, D. Ashley Robinson, Gaynor Randle, Edward J. Feil, Hajo Grundmann, and Brian G. Spratt Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7687–7692. Published online 2002 May 21. doi: 10.1073/pnas.122108599.PMCID: PMC124322 Synergistic transcriptional activation by one regulatory protein in response to two metabolites Becky M. Bundy, Lauren S. Collier, Timothy R. Hoover, and Ellen L. Neidle Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7693–7698. Published online 2002 May 21. doi: 10.1073/pnas.102605799.PMCID: PMC124324 Neurobiology Neuronal deactivation explains decreased cerebellar blood flow in response to focal cerebral ischemia or suppressed neocortical function Lorenz Gold and Martin Lauritzen Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7699–7704. Published online 2002 May 21. doi: 10.1073/pnas.112012499.PMCID: PMC124326 From the Cover: Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice Joo-Yong Lee, Toby B. Cole, Richard D. Palmiter, Sang Won Suh, and Jae-Young Koh Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7705–7710. Published online 2002 April 30. doi: 10.1073/pnas.092034699.PMCID: PMC124328 From the Cover: Identification of a family of calcium sensors as protein ligands of inositol trisphosphate receptor Ca2+ release channels Jun Yang, Sean McBride, Don-On Daniel Mak, Noga Vardi, Krzysztof Palczewski, Françoise Haeseleer, and J. Kevin Foskett Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7711–7716. Published online 2002 May 7. doi: 10.1073/pnas.102006299.PMCID: PMC124329 Permissive proteolytic activity for visual cortical plasticity Nobuko Mataga, Nobuo Nagai, and Takao K. Hensch Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7717–7721. Published online 2002 May 21. doi: 10.1073/pnas.102088899.PMCID: PMC124331 Opposing actions of adrenal androgens and glucocorticoids on alternative splicing of Slo potassium channels in bovine chromaffin cells Guey-Jen Lai and David P. McCobb Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7722–7727. doi: 10.1073/pnas.112619799.PMCID: PMC124333 Bimodal regulation of mPeriod promoters by CREB-dependent signaling and CLOCK/BMAL1 activity Zdenka Travnickova-Bendova, Nicolas Cermakian, Steven M. Reppert, and Paolo Sassone-Corsi Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7728–7733. Published online 2002 May 14. doi: 10.1073/pnas.102075599.PMCID: PMC124335 Corticotropin-releasing factor receptor 2 is a tonic suppressor of vascularization Tracy L. Bale, Frank J. Giordano, Reed P. Hickey, Yan Huang, Anjali K. Nath, Kirk L. Peterson, Wylie W. Vale, and Kuo-Fen Lee Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7734–7739. Published online 2002 May 21. doi: 10.1073/pnas.102187099.PMCID: PMC124337 Molecular dissection of hippocampal theta-burst pairing potentiation D. A. Hoffman, R. Sprengel, and B. Sakmann Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7740–7745. Published online 2002 May 21. doi: 10.1073/pnas.092157999.PMCID: PMC124338 Altered synaptic plasticity in a mouse model of fragile X mental retardation Kimberly M. Huber, Sean M. Gallagher, Stephen T. Warren, and Mark F. Bear Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7746–7750. Published online 2002 May 21. doi: 10.1073/pnas.122205699.PMCID: PMC124340 A polymorphic gene nested within an intron of the tau gene: Implications for Alzheimer's disease Chris Conrad, Cintia Vianna, Melissa Freeman, and Peter Davies Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7751–7756. Published online 2002 May 14. doi: 10.1073/pnas.112194599.PMCID: PMC124341 Pharmacology Stage-specific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases Simona Iezzi, Giulio Cossu, Clara Nervi, Vittorio Sartorelli, and Pier Lorenzo Puri Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7757–7762. doi: 10.1073/pnas.112218599.PMCID: PMC124343 Physiology Nitric oxide reaction with red blood cells and hemoglobin under heterogeneous conditions Tae H. Han, Daniel R. Hyduke, Mark W. Vaughn, Jon M. Fukuto, and James C. Liao Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7763–7768. Published online 2002 May 21. doi: 10.1073/pnas.122118299.PMCID: PMC124345 Rhesus expression in a green alga is regulated by CO2 Eric Soupene, Natalie King, Eithne Feild, Phillip Liu, Krishna K. Niyogi, Cheng-Han Huang, and Sydney Kustu Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7769–7773. Published online 2002 May 21. doi: 10.1073/pnas.112225599.PMCID: PMC124347 Heteromerization of Kir2.x potassium channels contributes to the phenotype of Andersen's syndrome Regina Preisig-Müller, Günter Schlichthörl, Tobias Goerge, Steffen Heinen, Andrea Brüggemann, Sindhu Rajan, Christian Derst, Rüdiger W. Veh, and Jürgen Daut Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7774–7779. Published online 2002 May 21. doi: 10.1073/pnas.102609499.PMCID: PMC124349 Shear stress regulates the endothelial Kir2.1 ion channel Jeff H. Hoger, Victor I. Ilyin, Scott Forsyth, and Anne Hoger Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7780–7785. Published online 2002 May 21. doi: 10.1073/pnas.102184999.PMCID: PMC124350 Plant Biology An Arabidopsis mutation in translation elongation factor 2 causes superinduction of CBF/DREB1 transcription factor genes but blocks the induction of their downstream targets under low temperatures Yan Guo, Liming Xiong, Manabu Ishitani, and Jian-Kang Zhu Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7786–7791. Published online 2002 May 14. doi: 10.1073/pnas.112040099.PMCID: PMC124352 Induced instability of two Arabidopsis constitutive pathogen-response alleles Trevor L. Stokes and Eric J. Richards Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7792–7796. Published online 2002 May 21. doi: 10.1073/pnas.112040999.PMCID: PMC124354 An Arabidopsis gene encoding an α-xylosyltransferase involved in xyloglucan biosynthesis Ahmed Faik, Nicholas J. Price, Natasha V. Raikhel, and Kenneth Keegstra Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7797–7802. Published online 2002 May 14. doi: 10.1073/pnas.102644799.PMCID: PMC124356 Psychology Hemispheric asymmetry in human lateral prefrontal cortex during cognitive set shifting Seiki Konishi, Toshihiro Hayashi, Idai Uchida, Hideyuki Kikyo, Emi Takahashi, and Yasushi Miyashita Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7803–7808. Published online 2002 May 21. doi: 10.1073/pnas.122644899.PMCID: PMC124358 Corrections Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7809. Published online 2002 May 21. doi: 10.1073/pnas.122187199.PMCID: PMC124223 Corrects: Monica V. Kumar, et al. Differential effects of a centrally acting fatty acid synthase inhibitor in lean and obese mice. Proc Natl Acad Sci U S A. 2002 February 19; 99(4): 1921–1925. Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7809. Published online 2002 May 21. doi: 10.1073/pnas.112147399.PMCID: PMC124426 Corrects: Brian Kuhlman, et al. Conversion of monomeric protein L to an obligate dimer by computational protein design. Proc Natl Acad Sci U S A. 2001 September 11; 98(19): 10687–10691. Correction Eleonora Palma, Anna M. Mileo, Ataúlfo Martínez-Torres, Fabrizio Eusebi, and Ricardo Miledi Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7809. Published online 2002 May 21. doi: 10.1073/pnas.122189499.PMCID: PMC124224 Corrects: Eleonora Palma, et al. Some properties of human neuronal α7 nicotinic acetylcholine receptors fused to the green fluorescent protein. Proc Natl Acad Sci U S A. 2002 March 19; 99(6): 3950–3955. Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7809. Published online 2002 May 21. doi: 10.1073/pnas.112147699.PMCID: PMC124225 Corrects: Thomas Weber, et al. Thyroid hormone is a critical determinant for the regulation of the cochlear motor protein prestin. Proc Natl Acad Sci U S A. 2002 March 5; 99(5): 2901–2906. Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7809. doi: 10.1073/pnas.122207399.PMCID: PMC124226 Corrects: Gabriella Colucci, et al. GCR1, the putative Arabidopsis G protein-coupled receptor gene is cell cycle-regulated, and its overexpression abolishes seed dormancy and shortens time to flowering. Proc Natl Acad Sci U S A. 2002 April 2; 99(7): 4736–4741. |