| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1735–1736. doi: 10.1073/iti0607104.PMCID: PMC1794317 Editorial Sustainability Science: A room of its own Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1737–1738. doi: 10.1073/pnas.0611291104.PMCID: PMC1794267 Commentaries The incredible, edible, and therapeutic egg James N. Petitte and Paul E. Mozdziak Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1739–1740. Published online 2007 February 1. doi: 10.1073/pnas.0611652104.PMCID: PMC1794276 Synthetic ecology: A model system for cooperation Maitreya J. Dunham Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1741–1742. Published online 2007 January 31. doi: 10.1073/pnas.0611067104.PMCID: PMC1794274 Malarial fever: Hemozoin is involved but Toll-free Ralf R. Schumann Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1743–1744. Published online 2007 February 1. doi: 10.1073/pnas.0610874104.PMCID: PMC1794284 Perspective Embryo stability and vulnerability in an always changing world Amro Hamdoun and David Epel Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1745–1750. Published online 2007 January 30. doi: 10.1073/pnas.0610108104.PMCID: PMC1794293 Profile Profile of James P. Kennett Tinsley H. Davis Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1751–1753. Published online 2007 January 31. doi: 10.1073/pnas.0609142104.PMCID: PMC1794309 Physical Sciences Applied Mathematics From the Cover: Synthetic cooperation in engineered yeast populations Wenying Shou, Sri Ram, and Jose M. G. Vilar Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1877–1882. Published online 2007 January 31. doi: 10.1073/pnas.0610575104.PMCID: PMC1794266 Applied Physical Sciences Hyperpolarized water as an authentic magnetic resonance imaging contrast agent Evan R. McCarney, Brandon D. Armstrong, Mark D. Lingwood, and Songi Han Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1754–1759. Published online 2007 January 30. doi: 10.1073/pnas.0610540104.PMCID: PMC1794264 Physics From the Cover: Complex network analysis of free-energy landscapes D. Gfeller, P. De Los Rios, A. Caflisch, and F. Rao Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1817–1822. Published online 2007 January 31. doi: 10.1073/pnas.0608099104.PMCID: PMC1794291 Statistics Sequential Monte Carlo without likelihoods S. A. Sisson, Y. Fan, and Mark M. Tanaka Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1760–1765. Published online 2007 January 30. doi: 10.1073/pnas.0607208104.PMCID: PMC1794282 Biological Sciences Agricultural Sciences Transgenic induction of mitochondrial rearrangements for cytoplasmic male sterility in crop plants Ajay Pal S. Sandhu, Ricardo V. Abdelnoor, and Sally A. Mackenzie Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1766–1770. Published online 2007 January 29. doi: 10.1073/pnas.0609344104.PMCID: PMC1783905 Applied Biological Sciences From the Cover: Oviduct-specific expression of two therapeutic proteins in transgenic hens S. G. Lillico, A. Sherman, M. J. McGrew, C. D. Robertson, J. Smith, C. Haslam, P. Barnard, P. A. Radcliffe, K. A. Mitrophanous, E. A. Elliot, and H. M. Sang Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1771–1776. Published online 2007 January 26. doi: 10.1073/pnas.0610401104.PMCID: PMC1783527 Global reconstruction of the human metabolic network based on genomic and bibliomic data Natalie C. Duarte, Scott A. Becker, Neema Jamshidi, Ines Thiele, Monica L. Mo, Thuy D. Vo, Rohith Srivas, and Bernhard Ø. Palsson Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1777–1782. Published online 2007 January 31. doi: 10.1073/pnas.0610772104.PMCID: PMC1794290 Biochemistry Crystal structure of the N-terminal domain of the human protooncogene Nup214/CAN Johanna Napetschnig, Günter Blobel, and André Hoelz Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1783–1788. Published online 2007 January 30. doi: 10.1073/pnas.0610828104.PMCID: PMC1794303 Substrate interactions with human ferrochelatase Amy Medlock, Larkin Swartz, Tamara A. Dailey, Harry A. Dailey, and William N. Lanzilotta Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1789–1793. Published online 2007 January 29. doi: 10.1073/pnas.0606144104.PMCID: PMC1794275 Inorganic polyphosphate essential for lytic growth of phages P1 and fd Li Li, Narayana N. Rao, and Arthur Kornberg Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1794–1799. Published online 2007 January 29. doi: 10.1073/pnas.0610763104.PMCID: PMC1794287 Effect of phosphorylation and S–S bond-induced dimerization on DNA binding and transcriptional activation by C/EBPβ Jae-woo Kim, Qi-Qun Tang, Xi Li, and M. Daniel Lane Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1800–1804. Published online 2007 January 30. doi: 10.1073/pnas.0611137104.PMCID: PMC1794285 SUMO modification regulates inactivation of the voltage-gated potassium channel Kv1.5 Mark D. Benson, Qiu-Ju Li, Katherine Kieckhafer, David Dudek, Matthew R. Whorton, Roger K. Sunahara, Jorge A. Iñiguez-Lluhí, and Jeffrey R. Martens Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1805–1810. Published online 2007 January 29. doi: 10.1073/pnas.0606702104.PMCID: PMC1794304 The tail of the ParG DNA segregation protein remodels ParF polymers and enhances ATP hydrolysis via an arginine finger-like motif Daniela Barillà, Emma Carmelo, and Finbarr Hayes Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1811–1816. Published online 2007 January 29. doi: 10.1073/pnas.0607216104.PMCID: PMC1794263 Biophysics From the Cover: Complex network analysis of free-energy landscapes D. Gfeller, P. De Los Rios, A. Caflisch, and F. Rao Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1817–1822. Published online 2007 January 31. doi: 10.1073/pnas.0608099104.PMCID: PMC1794291 The optimal height of the synaptic cleft Leonid P. Savtchenko and Dmitri A. Rusakov Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1823–1828. Published online 2007 January 29. doi: 10.1073/pnas.0606636104.PMCID: PMC1783902 Cell Biology Protective role of autophagy against Vibrio cholerae cytolysin, a pore-forming toxin from V. cholerae Maximiliano Gabriel Gutierrez, Hector Alex Saka, Isabel Chinen, Felipe C. M. Zoppino, Tamotsu Yoshimori, Jose Luis Bocco, and María Isabel Colombo Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1829–1834. Published online 2007 January 31. doi: 10.1073/pnas.0601437104.PMCID: PMC1794277 Lack of myostatin results in excessive muscle growth but impaired force generation Helge Amthor, Raymond Macharia, Roberto Navarrete, Markus Schuelke, Susan C. Brown, Anthony Otto, Thomas Voit, Francesco Muntoni, Gerta Vrbóva, Terence Partridge, Peter Zammit, Lutz Bunger, and Ketan Patel Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1835–1840. Published online 2007 January 31. doi: 10.1073/pnas.0604893104.PMCID: PMC1794294 BLIMP1 regulates cell growth through repression of p53 transcription Junli Yan, Jianming Jiang, Ching Aeng Lim, Qiang Wu, Huck-Hui Ng, and Keh-Chuang Chin Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1841–1846. Published online 2007 January 30. doi: 10.1073/pnas.0605562104.PMCID: PMC1784014 Polo-like kinase 3 is required for entry into S phase Wendy C. Zimmerman and Raymond L. Erikson Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1847–1852. Published online 2007 January 30. doi: 10.1073/pnas.0610856104.PMCID: PMC1794279 Influenza virus targets the mRNA export machinery and the nuclear pore complex Neal Satterly, Pei-Ling Tsai, Jan van Deursen, Daniel R. Nussenzveig, Yaming Wang, Paula A. Faria, Agata Levay, David E. Levy, and Beatriz M. A. Fontoura Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1853–1858. Published online 2007 January 31. doi: 10.1073/pnas.0610977104.PMCID: PMC1794296 LARK activates posttranscriptional expression of an essential mammalian clock protein, PERIOD1 Shihoko Kojima, Ken Matsumoto, Matsumi Hirose, Miyuki Shimada, Mamoru Nagano, Yasufumi Shigeyoshi, Shin-ichi Hoshino, Kumiko Ui-Tei, Kaoru Saigo, Carla B. Green, Yoshiyuki Sakaki, and Hajime Tei Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1859–1864. Published online 2007 January 30. doi: 10.1073/pnas.0607567104.PMCID: PMC1794262 Developmental Biology From the Cover: SOX9 is required for maintenance of the pancreatic progenitor cell pool Philip A. Seymour, Kristine K. Freude, Man N. Tran, Erin E. Mayes, Jan Jensen, Ralf Kist, Gerd Scherer, and Maike Sander Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1865–1870. Published online 2007 January 31. doi: 10.1073/pnas.0609217104.PMCID: PMC1794281 Maternal neoangiogenesis during pregnancy partly derives from fetal endothelial progenitor cells Sau Nguyen Huu, Michèle Oster, Serge Uzan, Fabrice Chareyre, Sélim Aractingi, and Kiarash Khosrotehrani Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1871–1876. Published online 2007 January 31. doi: 10.1073/pnas.0606490104.PMCID: PMC1794298 Ecology From the Cover: Synthetic cooperation in engineered yeast populations Wenying Shou, Sri Ram, and Jose M. G. Vilar Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1877–1882. Published online 2007 January 31. doi: 10.1073/pnas.0610575104.PMCID: PMC1794266 Genome dynamics in a natural archaeal population Eric E. Allen, Gene W. Tyson, Rachel J. Whitaker, John C. Detter, Paul M. Richardson, and Jillian F. Banfield Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1883–1888. Published online 2007 January 31. doi: 10.1073/pnas.0604851104.PMCID: PMC1794283 Evolution Antioxidant defense response in a galling insect Omprakash Mittapalli, Jonathan J. Neal, and Richard H. Shukle Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1889–1894. Published online 2007 January 29. doi: 10.1073/pnas.0604722104.PMCID: PMC1783901 Massive amplification of rolling-circle transposons in the lineage of the bat Myotis lucifugus Ellen J. Pritham and Cédric Feschotte Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1895–1900. Published online 2007 January 29. doi: 10.1073/pnas.0609601104.PMCID: PMC1794268 Genetics Chromosomal context directs high-frequency precise excision of IS492 in Pseudoalteromonas atlantica Brian P. Higgins, Chandra D. Carpenter, and Anna C. Karls Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1901–1906. Published online 2007 January 30. doi: 10.1073/pnas.0608633104.PMCID: PMC1794265 An editing-defective aminoacyl-tRNA synthetase is mutagenic in aging bacteria via the SOS response Jamie M. Bacher and Paul Schimmel Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1907–1912. Published online 2007 January 30. doi: 10.1073/pnas.0610835104.PMCID: PMC1794292 Immunology NF-κB prevents β cell death and autoimmune diabetes in NOD mice Sunshin Kim, Isabelle Millet, Hun Sik Kim, Ja Young Kim, Myoung Sook Han, Moon-Kyu Lee, Kwang-Won Kim, Robert S. Sherwin, Michael Karin, and Myung-Shik Lee Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1913–1918. Published online 2007 January 31. doi: 10.1073/pnas.0610690104.PMCID: PMC1794308 Medical Sciences From the Cover: Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9 Peggy Parroche, Fanny N. Lauw, Nadege Goutagny, Eicke Latz, Brian G. Monks, Alberto Visintin, Kristen A. Halmen, Marc Lamphier, Martin Olivier, Daniella C. Bartholomeu, Ricardo T. Gazzinelli, and Douglas T. Golenbock Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1919–1924. Published online 2007 January 29. doi: 10.1073/pnas.0608745104.PMCID: PMC1794278 Noninvasive and real-time assessment of reconstructed functional human endometrium in NOD/SCID/γcnull immunodeficient mice Hirotaka Masuda, Tetsuo Maruyama, Emi Hiratsu, Junichi Yamane, Akio Iwanami, Takashi Nagashima, Masanori Ono, Hiroyuki Miyoshi, Hirotaka James Okano, Mamoru Ito, Norikazu Tamaoki, Tatsuji Nomura, Hideyuki Okano, Yumi Matsuzaki, and Yasunori Yoshimura Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1925–1930. Published online 2007 January 29. doi: 10.1073/pnas.0604310104.PMCID: PMC1794295 Partial rescue of MeCP2 deficiency by postnatal activation of MeCP2 Emanuela Giacometti, Sandra Luikenhuis, Caroline Beard, and Rudolf Jaenisch Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1931–1936. Published online 2007 January 31. doi: 10.1073/pnas.0610593104.PMCID: PMC1794312 Positron emission tomography with computed tomography imaging of neuroinflammation in experimental autoimmune encephalomyelitis Caius G. Radu, Chengyi J. Shu, Stephanie M. Shelly, Michael E. Phelps, and Owen N. Witte Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1937–1942. Published online 2007 January 29. doi: 10.1073/pnas.0610544104.PMCID: PMC1783904 Potentiation of mammary cancer inhibition by combination of antagonists of growth hormone-releasing hormone with docetaxel Stefan Buchholz, Andrew V. Schally, Jörg B. Engel, Florian Hohla, Elmar Heinrich, Frank Koester, Jozsef L. Varga, and Gabor Halmos Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1943–1946. Published online 2007 January 29. doi: 10.1073/pnas.0610860104.PMCID: PMC1794297 Microbiology A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages Robert Van der Geize, Katherine Yam, Thomas Heuser, Maarten H. Wilbrink, Hirofumi Hara, Matthew C. Anderton, Edith Sim, Lubbert Dijkhuizen, Julian E. Davies, William W. Mohn, and Lindsay D. Eltis Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1947–1952. Published online 2007 January 30. doi: 10.1073/pnas.0605728104.PMCID: PMC1794314 Neuroscience Relational representation in the olfactory system Thomas A. Cleland, Brett A. Johnson, Michael Leon, and Christiane Linster Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1953–1958. Published online 2007 January 29. doi: 10.1073/pnas.0608564104.PMCID: PMC1794271 Axonal-SMN (a-SMN), a protein isoform of the survival motor neuron gene, is specifically involved in axonogenesis Veronica Setola, Mineko Terao, Denise Locatelli, Stefania Bassanini, Enrico Garattini, and Giorgio Battaglia Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1959–1964. Published online 2007 January 29. doi: 10.1073/pnas.0610660104.PMCID: PMC1794299 Cells infected with scrapie and Creutzfeldt–Jakob disease agents produce intracellular 25-nm virus-like particles Laura Manuelidis, Zhoa-Xue Yu, Nuria Barquero, and Brian Mullins Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1965–1970. Published online 2007 January 31. doi: 10.1073/pnas.0610999104.PMCID: PMC1794316 APL-1, a Caenorhabditis elegans protein related to the human β-amyloid precursor protein, is essential for viability Angela Hornsten, Jason Lieberthal, Shruti Fadia, Richard Malins, Lawrence Ha, Xiaomeng Xu, Isabelle Daigle, Mindy Markowitz, Gregory O'Connor, Ronald Plasterk, and Chris Li Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1971–1976. Published online 2007 January 31. doi: 10.1073/pnas.0603997104.PMCID: PMC1794273 GSTπ expression mediates dopaminergic neuron sensitivity in experimental parkinsonism Michelle Smeyne, Justin Boyd, Kennie Raviie Shepherd, Yun Jiao, Brooks Barnes Pond, Matthew Hatler, Roland Wolf, Colin Henderson, and Richard Jay Smeyne Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1977–1982. Published online 2007 January 31. doi: 10.1073/pnas.0610978104.PMCID: PMC1785361 The power of automated high-resolution behavior analysis revealed by its application to mouse models of Huntington's and prion diseases Andrew D. Steele, Walker S. Jackson, Oliver D. King, and Susan Lindquist Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1983–1988. Published online 2007 January 29. doi: 10.1073/pnas.0610779104.PMCID: PMC1794260 Nucleus- and cell-specific gene expression in monkey thalamus Karl D. Murray, Prabhakara V. Choudary, and Edward G. Jones Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1989–1994. Published online 2007 January 29. doi: 10.1073/pnas.0610742104.PMCID: PMC1783903 mGluR5 stimulates gliotransmission in the nucleus accumbens Marcello D'Ascenzo, Tommaso Fellin, Miho Terunuma, Raquel Revilla-Sanchez, David F. Meaney, Yves P. Auberson, Stephen J. Moss, and Philip G. Haydon Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 1995–2000. Published online 2007 January 26. doi: 10.1073/pnas.0609408104.PMCID: PMC1794302 Pharmacology Structural basis for nucleotide exchange on Gαi subunits and receptor coupling specificity Christopher A. Johnston and David P. Siderovski Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 2001–2006. Published online 2007 January 30. doi: 10.1073/pnas.0608599104.PMCID: PMC1794300 Physiology Age-dependent regulation of chromaffin cell proliferation by growth factors, dehydroepiandrosterone (DHEA), and DHEA sulfate Flavie Sicard, Monika Ehrhart-Bornstein, Denis Corbeil, Simone Sperber, Alexander W. Krug, Christian G. Ziegler, Valeria Rettori, Samuel M. McCann, and Stefan R. Bornstein Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 2007–2012. Published online 2007 January 30. doi: 10.1073/pnas.0610898104.PMCID: PMC1794270 Substance P mediates antiapoptotic responses in human colonocytes by Akt activation Hon-Wai Koon, Dezheng Zhao, Yanai Zhan, Mary P. Moyer, and Charalabos Pothoulakis Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 2013–2018. Published online 2007 January 30. doi: 10.1073/pnas.0610664104.PMCID: PMC1794289 Plant Biology A plant porphyria related to defects in plastid import of protochlorophyllide oxidoreductase A Stephan Pollmann, Armin Springer, Frank Buhr, Abder Lahroussi, Iga Samol, Jean-Marc Bonneville, Gabrielle Tichtinsky, Diter von Wettstein, Christiane Reinbothe, and Steffen Reinbothe Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 2019–2023. Published online 2007 January 29. doi: 10.1073/pnas.0610934104.PMCID: PMC1794315 Corrections Correction for Zeri et al., Structure of the coat protein in fd filamentous bacteriophage particles determined by solid-state NMR spectroscopy Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 2024. Published online 2007 January 22. doi: 10.1073/pnas.0610764104.PMCID: PMC1794269 Corrects: Ana Carolina Zeri, et al. Structure of the coat protein in fd filamentous bacteriophage particles determined by solid-state NMR spectroscopy. Proc Natl Acad Sci U S A. 2003 May 27; 100(11): 6458–6463. Correction for Wang et al., Bcl10 plays a critical role in NF-κB activation induced by G protein-coupled receptors Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 2024. Published online 2007 January 22. doi: 10.1073/pnas.0611566104.PMCID: PMC1794305 Corrects: Donghai Wang, et al. Bcl10 plays a critical role in NF-κB activation induced by G protein-coupled receptors. Proc Natl Acad Sci U S A. 2007 January 2; 104(1): 145–150. Correction for Wedmann et al., The first fossil leaf insect: 47 million years of specialized cryptic morphology and behavior Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 2024. Published online 2007 January 22. doi: 10.1073/pnas.0700092104.PMCID: PMC1794313 Corrects: Sonja Wedmann, et al. The first fossil leaf insect: 47 million years of specialized cryptic morphology and behavior. Proc Natl Acad Sci U S A. 2007 January 9; 104(2): 565–569. Correction for Casola et al., Tracking germinal center B cells expressing germ-line immunoglobulin γ1 transcripts by conditional gene targeting Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 2025. Published online 2007 January 16. doi: 10.1073/pnas.0611564104.PMCID: PMC1794272 Corrects: Stefano Casola, et al. Tracking germinal center B cells expressing germ-line immunoglobulin γ1 transcripts by conditional gene targeting. Proc Natl Acad Sci U S A. 2006 May 9; 103(19): 7396–7401. Correction for Galkin et al., Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK Proc Natl Acad Sci U S A. 2007 February 6; 104(6): 2025. Published online 2007 January 16. doi: 10.1073/pnas.0611563104.PMCID: PMC1794286 Corrects: Anna V. Galkin, et al. Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK. Proc Natl Acad Sci U S A. 2007 January 2; 104(1): 270–275. |