| | This journal provides immediate access to some articles. In This Issue Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9431–9432. doi: 10.1073/iti2705102.PMCID: PMC1198917 Commentary Reversible molecular photoswitches: A key technology for nanoscience and fluorescence imaging Markus Sauer Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9433–9434. Published online 2005 June 27. doi: 10.1073/pnas.0504264102.PMCID: PMC1172283 Profile Profile of Bruce D. Smith Regina Nuzzo Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9435–9437. Published online 2005 June 27. doi: 10.1073/pnas.0503921102.PMCID: PMC1172269 Physical Sciences Applied Mathematics Sparse nonnegative solution of underdetermined linear equations by linear programming David L. Donoho and Jared Tanner Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9446–9451. Published online 2005 June 23. doi: 10.1073/pnas.0502269102.PMCID: PMC1172251 Neighborliness of randomly projected simplices in high dimensions David L. Donoho and Jared Tanner Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9452–9457. Published online 2005 June 22. doi: 10.1073/pnas.0502258102.PMCID: PMC1172250 Chemistry Reduced water density at hydrophobic surfaces: Effect of dissolved gases Dhaval A. Doshi, Erik B. Watkins, Jacob N. Israelachvili, and Jaroslaw Majewski Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9458–9462. Published online 2005 June 23. doi: 10.1073/pnas.0504034102.PMCID: PMC1172272 Protein identification using sequential ion/ion reactions and tandem mass spectrometry Joshua J. Coon, Beatrix Ueberheide, John E. P. Syka, Deanna D. Dryhurst, Juan Ausio, Jeffrey Shabanowitz, and Donald F. Hunt Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9463–9468. Published online 2005 June 27. doi: 10.1073/pnas.0503189102.PMCID: PMC1172258 Engineering From the Cover: Mechanics of receptor-mediated endocytosis Huajian Gao, Wendong Shi, and Lambert B. Freund Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9469–9474. Published online 2005 June 22. doi: 10.1073/pnas.0503879102.PMCID: PMC1172266 Physics Hydrophobic hydration from small to large lengthscales: Understanding and manipulating the crossover Sowmianarayanan Rajamani, Thomas M. Truskett, and Shekhar Garde Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9475–9480. Published online 2005 June 22. doi: 10.1073/pnas.0504089102.PMCID: PMC1172274 Statistics Sampling motifs on phylogenetic trees Xiaoman Li and Wing H. Wong Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9481–9486. Published online 2005 June 27. doi: 10.1073/pnas.0501620102.PMCID: PMC1160516 Biological Sciences Biochemistry Roles of steroid receptor coactivator (SRC)-1 and transcriptional intermediary factor (TIF) 2 in androgen receptor activity in mice Xiangcang Ye, Sang Jun Han, Sophia Y. Tsai, Francesco J. DeMayo, Jianming Xu, Ming-Jer Tsai, and Bert W. O'Malley Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9487–9492. Published online 2005 June 27. doi: 10.1073/pnas.0503577102.PMCID: PMC1172261 Silencing the expression of multiple Gβ-subunits eliminates signaling mediated by all four families of G proteins Jong-Ik Hwang, Sangdun Choi, Iain D. C. Fraser, Mi Sook Chang, and Melvin I. Simon Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9493–9498. Published online 2005 June 27. doi: 10.1073/pnas.0503503102.PMCID: PMC1172260 Efficient synthetic inhibitors of anthrax lethal factor Martino Forino, Sherida Johnson, Thiang Y. Wong, Dmitri V. Rozanov, Alexei Y. Savinov, Wei Li, Roberto Fattorusso, Barbara Becattini, Andrew J. Orry, Dawoon Jung, Ruben A. Abagyan, Jeffrey W. Smith, Ken Alibek, Robert C. Liddington, Alex Y. Strongin, and Maurizio Pellecchia Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9499–9504. Published online 2005 June 27. doi: 10.1073/pnas.0502733102.PMCID: PMC1160517 Structural and biochemical basis for selective repression of the orphan nuclear receptor liver receptor homolog 1 by small heterodimer partner Yong Li, Mihwa Choi, Kelly Suino, Amanda Kovach, Jennifer Daugherty, Steven A. Kliewer, and H. Eric Xu Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9505–9510. Published online 2005 June 23. doi: 10.1073/pnas.0501204102.PMCID: PMC1157103 Biophysics From the Cover: Mechanics of receptor-mediated endocytosis Huajian Gao, Wendong Shi, and Lambert B. Freund Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9469–9474. Published online 2005 June 22. doi: 10.1073/pnas.0503879102.PMCID: PMC1172266 Sampling motifs on phylogenetic trees Xiaoman Li and Wing H. Wong Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9481–9486. Published online 2005 June 27. doi: 10.1073/pnas.0501620102.PMCID: PMC1160516 From the Cover: Reversible single-molecule photoswitching in the GFP-like fluorescent protein Dronpa Satoshi Habuchi, Ryoko Ando, Peter Dedecker, Wendy Verheijen, Hideaki Mizuno, Atsushi Miyawaki, and Johan Hofkens Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9511–9516. Published online 2005 June 22. doi: 10.1073/pnas.0500489102.PMCID: PMC1157093 Hysteresis in a synthetic mammalian gene network Beat P. Kramer and Martin Fussenegger Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9517–9522. Published online 2005 June 22. doi: 10.1073/pnas.0500345102.PMCID: PMC1172236 Cell Biology Isoforms of ΔNp63 and the migration of ocular limbal cells in human corneal regeneration Enzo Di Iorio, Vanessa Barbaro, Alessandro Ruzza, Diego Ponzin, Graziella Pellegrini, and Michele De Luca Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9523–9528. Published online 2005 June 27. doi: 10.1073/pnas.0503437102.PMCID: PMC1172259 The Rho GTP exchange factor Lfc promotes spindle assembly in early mitosis Christopher J. Bakal, Dina Finan, José LaRose, Clark D. Wells, Gerald Gish, Sarang Kulkarni, Paulo DeSepulveda, Andrew Wilde, and Robert Rottapel Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9529–9534. Published online 2005 June 23. doi: 10.1073/pnas.0504190102.PMCID: PMC1157106 Ecology Coevolutionary arms races between bacteria and bacteriophage J. S. Weitz, H. Hartman, and S. A. Levin Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9535–9540. Published online 2005 June 23. doi: 10.1073/pnas.0504062102.PMCID: PMC1172273 Evolution The application of statistical physics to evolutionary biology Guy Sella and Aaron E. Hirsh Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9541–9546. Published online 2005 June 24. doi: 10.1073/pnas.0501865102.PMCID: PMC1172247 From the Cover: Origin of the Eumetazoa: Testing ecological predictions of molecular clocks against the Proterozoic fossil record Kevin J. Peterson and Nicholas J. Butterfield Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9547–9552. Published online 2005 June 27. doi: 10.1073/pnas.0503660102.PMCID: PMC1172262 Genetics Extreme hyperopia is the result of null mutations in MFRP, which encodes a Frizzled-related protein Olof H. Sundin, Gregory S. Leppert, Eduardo D. Silva, Jun-Ming Yang, Sharola Dharmaraj, Irene H. Maumenee, Luisa Coutinho Santos, Cameron F. Parsa, Elias I. Traboulsi, Karl W. Broman, Cathy DiBernardo, Janet S. Sunness, Jeffrey Toy, and Ethan M. Weinberg Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9553–9558. Published online 2005 June 23. doi: 10.1073/pnas.0501451102.PMCID: PMC1172243 Nonlinear protein degradation and the function of genetic circuits Nicolas E. Buchler, Ulrich Gerland, and Terence Hwa Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9559–9564. Published online 2005 June 22. doi: 10.1073/pnas.0409553102.PMCID: PMC1172234 An intracellular phosphate buffer filters transient fluctuations in extracellular phosphate levels Melissa R. Thomas and Erin K. O'Shea Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9565–9570. Published online 2005 June 22. doi: 10.1073/pnas.0501122102.PMCID: PMC1157094 Immunology Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells Christopher A. Klebanoff, Luca Gattinoni, Parizad Torabi-Parizi, Keith Kerstann, Adela R. Cardones, Steven E. Finkelstein, Douglas C. Palmer, Paul A. Antony, Sam T. Hwang, Steven A. Rosenberg, Thomas A. Waldmann, and Nicholas P. Restifo Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9571–9576. Published online 2005 June 24. doi: 10.1073/pnas.0503726102.PMCID: PMC1172264 The evolution of vertebrate Toll-like receptors Jared C. Roach, Gustavo Glusman, Lee Rowen, Amardeep Kaur, Maureen K. Purcell, Kelly D. Smith, Leroy E. Hood, and Alan Aderem Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9577–9582. Published online 2005 June 23. doi: 10.1073/pnas.0502272102.PMCID: PMC1172252 CD26, adenosine deaminase, and adenosine receptors mediate costimulatory signals in the immunological synapse R. Pacheco, J. M. Martinez-Navio, M. Lejeune, N. Climent, H. Oliva, J. M. Gatell, T. Gallart, J. Mallol, C. Lluis, and R. Franco Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9583–9588. Published online 2005 June 27. doi: 10.1073/pnas.0501050102.PMCID: PMC1172240 IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation Rachel M. McLoughlin, Brendan J. Jenkins, Dianne Grail, Anwen S. Williams, Ceri A. Fielding, Clare R. Parker, Matthias Ernst, Nicholas Topley, and Simon A. Jones Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9589–9594. Published online 2005 June 23. doi: 10.1073/pnas.0501794102.PMCID: PMC1172246 Differential induction of IgE-mediated anaphylaxis after soluble vs. cell-bound tolerogenic peptide therapy of autoimmune encephalomyelitis Cassandra E. Smith, Todd N. Eagar, Jack L. Strominger, and Stephen D. Miller Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9595–9600. Published online 2005 June 27. doi: 10.1073/pnas.0504131102.PMCID: PMC1172278 Medical Sciences Complex humoral immune response against a benign tumor: Frequent antibody response against specific antigens as diagnostic targets Nicole Comtesse, Andrea Zippel, Sascha Walle, Dominik Monz, Christina Backes, Ulrike Fischer, Jens Mayer, Nicole Ludwig, Andreas Hildebrandt, Andreas Keller, Wolf-Ingo Steudel, Hans-Peter Lenhof, and Eckart Meese Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9601–9606. Published online 2005 June 27. doi: 10.1073/pnas.0500404102.PMCID: PMC1172238 Enhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure Xander H. T. Wehrens, Stephan E. Lehnart, Steven Reiken, Roel van der Nagel, Raymond Morales, Jie Sun, Zhenzhuang Cheng, Shi-Xiang Deng, Leon J. de Windt, Donald W. Landry, and Andrew R. Marks Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9607–9612. Published online 2005 June 22. doi: 10.1073/pnas.0500353102.PMCID: PMC1172237 c-Myc induces chromosomal rearrangements through telomere and chromosome remodeling in the interphase nucleus Sherif F. Louis, Bart J. Vermolen, Yuval Garini, Ian T. Young, Amanda Guffei, Zelda Lichtensztejn, Fabien Kuttler, Tony C. Y. Chuang, Sharareh Moshir, Virginie Mougey, Alice Y. C. Chuang, Paul Donald Kerr, Thierry Fest, Petra Boukamp, and Sabine Mai Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9613–9618. Published online 2005 June 27. doi: 10.1073/pnas.0407512102.PMCID: PMC1172233 The impact of HIV/AIDS on the control of tuberculosis in India B. G. Williams, R. Granich, L. S. Chauhan, N. S. Dharmshaktu, and C. Dye Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9619–9624. Published online 2005 June 23. doi: 10.1073/pnas.0501615102.PMCID: PMC1157104 High-resolution genomic profiles of human lung cancer Giovanni Tonon, Kwok-Kin Wong, Gautam Maulik, Cameron Brennan, Bin Feng, Yunyu Zhang, Deepak B. Khatry, Alexei Protopopov, Mingjian James You, Andrew J. Aguirre, Eric S. Martin, Zhaohui Yang, Hongbin Ji, Lynda Chin, and Ronald A. DePinho Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9625–9630. Published online 2005 June 27. doi: 10.1073/pnas.0504126102.PMCID: PMC1160520 Cardiac glycosides inhibit TNF-α/NF-κB signaling by blocking recruitment of TNF receptor-associated death domain to the TNF receptor Qingfeng Yang, Wei Huang, Catherine Jozwik, Yong Lin, Mirta Glasman, Hung Caohuy, Meera Srivastava, Dominic Esposito, William Gillette, James Hartley, and Harvey B. Pollard Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9631–9636. Published online 2005 June 27. doi: 10.1073/pnas.0504097102.PMCID: PMC1160519 Hypophosphatemia leads to rickets by impairing caspase-mediated apoptosis of hypertrophic chondrocytes Yves Sabbagh, Thomas O. Carpenter, and Marie B. Demay Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9637–9642. Published online 2005 June 23. doi: 10.1073/pnas.0502249102.PMCID: PMC1172249 Altered ultrasonic vocalization in mice with a disruption in the Foxp2 gene Weiguo Shu, Julie Y. Cho, Yuhui Jiang, Minhua Zhang, Donald Weisz, Gregory A. Elder, James Schmeidler, Rita De Gasperi, Miguel A. Gama Sosa, Donald Rabidou, Anthony C. Santucci, Daniel Perl, Edward Morrisey, and Joseph D. Buxbaum Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9643–9648. Published online 2005 June 27. doi: 10.1073/pnas.0503739102.PMCID: PMC1160518 Ras activity regulates cyclin E degradation by the Fbw7 pathway Alex C. Minella, Markus Welcker, and Bruce E. Clurman Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9649–9654. Published online 2005 June 24. doi: 10.1073/pnas.0503677102.PMCID: PMC1172263 Frag1, a homolog of alternative replication factor C subunits, links replication stress surveillance with apoptosis Hideshi Ishii, Taeko Inageta, Koshi Mimori, Toshiyuki Saito, Hiroki Sasaki, Masaharu Isobe, Masaki Mori, Carlo M. Croce, Kay Huebner, Keiya Ozawa, and Yusuke Furukawa Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9655–9660. Published online 2005 June 27. doi: 10.1073/pnas.0504222102.PMCID: PMC1172282 Microbiology Functional antagonism between Helicobacter pylori CagA and vacuolating toxin VacA in control of the NFAT signaling pathway in gastric epithelial cells Kazuyuki Yokoyama, Hideaki Higashi, Susumu Ishikawa, Yumiko Fujii, Satoshi Kondo, Hiroyuki Kato, Takeshi Azuma, Akihiro Wada, Toshiya Hirayama, Hiroyuki Aburatani, and Masanori Hatakeyama Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9661–9666. Published online 2005 June 24. doi: 10.1073/pnas.0502529102.PMCID: PMC1172255 An unusual internal ribosome entry site in the herpes simplex virus thymidine kinase gene Anthony Griffiths and Donald M. Coen Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9667–9672. Published online 2005 June 22. doi: 10.1073/pnas.0504132102.PMCID: PMC1172279 Neuroscience From the Cover: The human brain is intrinsically organized into dynamic, anticorrelated functional networks Michael D. Fox, Abraham Z. Snyder, Justin L. Vincent, Maurizio Corbetta, David C. Van Essen, and Marcus E. Raichle Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9673–9678. Published online 2005 June 23. doi: 10.1073/pnas.0504136102.PMCID: PMC1157105 Graded bidirectional synaptic plasticity is composed of switch-like unitary events Daniel H. O'Connor, Gayle M. Wittenberg, and Samuel S.-H. Wang Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9679–9684. Published online 2005 June 27. doi: 10.1073/pnas.0502332102.PMCID: PMC1172253 Increasing the power of functional maps of the medial temporal lobe by using large deformation diffeomorphic metric mapping Michael I. Miller, M. Faisal Beg, Can Ceritoglu, and Craig Stark Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9685–9690. Published online 2005 June 24. doi: 10.1073/pnas.0503892102.PMCID: PMC1172268 Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death Eunsung Junn, Hiroyuki Taniguchi, Byeong Seon Jeong, Xin Zhao, Hidenori Ichijo, and M. Maral Mouradian Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9691–9696. Published online 2005 June 27. doi: 10.1073/pnas.0409635102.PMCID: PMC1172235 Critical period for sensory experience-dependent survival of newly generated granule cells in the adult mouse olfactory bulb Masahiro Yamaguchi and Kensaku Mori Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9697–9702. Published online 2005 June 23. doi: 10.1073/pnas.0406082102.PMCID: PMC1157102 Plant Biology A database analysis method identifies an endogenous trans-acting short-interfering RNA that targets the Arabidopsis ARF2, ARF3, and ARF4 genes Leor Williams, Cristel C. Carles, Karen S. Osmont, and Jennifer C. Fletcher Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9703–9708. Published online 2005 June 24. doi: 10.1073/pnas.0504029102.PMCID: PMC1172271 Regulating the proton budget of higher plant photosynthesis Thomas J. Avenson, Jeffrey A. Cruz, Atsuko Kanazawa, and David M. Kramer Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9709–9713. Published online 2005 June 22. doi: 10.1073/pnas.0503952102.PMCID: PMC1172270 Population Biology Drug resistance in cancer: Principles of emergence and prevention Natalia L. Komarova and Dominik Wodarz Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9714–9719. Published online 2005 June 24. doi: 10.1073/pnas.0501870102.PMCID: PMC1172248 Psychology From the Cover: The distribution of response spectra in the lateral geniculate nucleus compared with reflectance spectra of Munsell color chips A. Kimball Romney, Roy G. D'Andrade, and Tarow Indow Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9720–9725. Published online 2005 June 23. doi: 10.1073/pnas.0503887102.PMCID: PMC1172267 Social Sciences Anthropology INAUGURAL ARTICLE by a Recently Elected Academy Member: Reassessing Coxcatlan Cave and the early history of domesticated plants in Mesoamerica Bruce D. Smith Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9438–9445. Published online 2005 May 20. doi: 10.1073/pnas.0502847102.PMCID: PMC1172257 Psychology Early experience affects the intergenerational transmission of infant abuse in rhesus monkeys Dario Maestripieri Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9726–9729. Published online 2005 June 27. doi: 10.1073/pnas.0504122102.PMCID: PMC1172276 Social Sciences On class differentials in educational attainment Robert Erikson, John H. Goldthorpe, Michelle Jackson, Meir Yaish, and D. R. Cox Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9730–9733. Published online 2005 June 23. doi: 10.1073/pnas.0502433102.PMCID: PMC1172254 Corrections Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9734. Published online 2005 June 16. doi: 10.1073/pnas.0504375102.PMCID: PMC1172284 Corrects: Kenji Miura, et al. The Arabidopsis SUMO E3 ligase SIZ1 controls phosphate deficiency responses. Proc Natl Acad Sci U S A. 2005 May 24; 102(21): 7760–7765. Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9734. Published online 2005 June 22. doi: 10.1073/pnas.0504548102.PMCID: PMC1172285 Corrects: Ian D. Davis, et al. Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad integrated antibody and CD4+ and CD8+ T cell responses in humans. Proc Natl Acad Sci U S A. 2004 July 20; 101(29): 10697–10702. Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9734. Published online 2005 June 24. doi: 10.1073/pnas.0504552102.PMCID: PMC1172286 Corrects: Xinchun Shen, et al. Scanning the human proteome for calmodulin-binding proteins. Proc Natl Acad Sci U S A. 2005 April 26; 102(17): 5969–5974. Proc Natl Acad Sci U S A. 2005 July 5; 102(27): 9734. Published online 2005 June 16. doi: 10.1073/pnas.0504625102.PMCID: PMC1172287 Corrects: Paul Alan Cox, et al. Diverse taxa of cyanobacteria produce β-N-methylamino-l-alanine, a neurotoxic amino acid. Proc Natl Acad Sci U S A. 2005 April 5; 102(14): 5074–5078. |