| | Staff Scientists and Clinicians
| Mary M. Herman, M.D. |
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Dr.
Herman is a Neuropathologist and Senior Staff Scientist in the Clinical
Brain Disorders Branch of the DIRP, NIMH. She graduated from the
University and Medical School at the University of Wisconsin in Madison, Wisconsin, and completed
residencies in Pathology and Neuropathology at Yale and Stanford Universities. She was on the faculty
of Stanford University for fifteen years, rising to Associate Professor of Pathology with tenure, followed by eleven years
as Professor of Pathology and Co-Director of Neuropathology at the University of Virginia. Dr. Herman
joined the NIMH in 1991 as a Special Expert in Neuropathology, followed by her present appointment in
1996. She is board-certified in Anatomical Pathology and Neuropathology. Dr. Herman has been a member of the Editorial Board of the Journal of Neuropathology on two occasions and is a member of numerous pathology societies as well as the Society of Biological Psychiatry and the Society for Neuroscience, among others. She has received the Merck Faculty Development Award from the Merck Foundation, a Research Career Development Award, and the Weil Award from the AANP.
She has published over 200 scientific articles. |
| Research Interests |
| Dr.
Herman is the Neuropathologist at the NIMH and collaborates
with the Clinical Brain Disorders Branch. She will be the Neuropathologist for
the proposed Neuropathology Core Facility in the
DIRP, NIMH. Her research interests in schizophrenia encompass
an evaluation of glial pathology and of COMT, growth factors,
and the morphometric analysis of neuronal populations
in the cerebrum and cerebellum. |
| Selected Publications: |
- Weickert, C.S., Ligons, D.L., Romanczyk, T., Ungaro, G., Hyde, T.M., Herman, M.M., Weinberger, D.R., and Kleinman, J.E.: Reductions in neurotrophin receptor mRNAs in the prefrontal cortex of patients with schizophrenia. Mol. Psychiatry , 10:637-650, 2005. (View PDF)
- Matsumoto, M., Weickert, C.S., Akil, M., Lipska, B.K., Hyde, T.M., Herman, M.M., Kleinman, J.E., and Weinberger, D.R.: Catechol O-methyl-transferase mRNA expression in human and rat brain: evidence for a role in cortical neuronal function. Neuroscience, 116:127-137, 2003. (View PDF)
- Selemon, L.D., Mrzljak, J., Kleinman, J.E., Herman, M.M., and Goldman-Rakic, P.S. Regional specificity in the neuropatholic substrates of schizophrenia: a morphometric analysis of Broca’s area 44 and area 9. Arch. of Gen. Psychiatry, 60:69-77, 2003. (View PDF)
- Damadzic, R., Shuangshoti, S., Giblen, G., and Herman, M.M.: Neuritic pathology is lacking in the entorhinal cortex, subiculum, and hippocampus in middle-aged adults with schizophrenia, bipolar disorder or unipolar depression. Acta Neuropathol., 103:488-494, 2002. (View PDF)
- Damadzic, R., Bigelow, L.B., Krimer, L.S., Goldenson, D.A., Saunders, R.C., Kleinman, J.E., and Herman, M.M. A quantitative immunohistochemical study of astrocytes in the entorhinal cortex in schizophrenia, bipolar disorder, and major depression: absence of significant astrogliosis. Brain Res. Bull., 55:611-618, 2001. (View PDF)
- Weickert, C.S., Webster, M.J., Hyde, T.M., Herman, M.M., Bachus, S.E., Bali, G., Weinberger, D.R., and Kleinman, J.E.: Reduced GAP-43 mRNA in dorsolateral prefrontal cortex of patients with schizophrenia. Cereb. Cortex, 11:136-147, 2001. (View PDF)
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