| | This journal provides immediate access to some articles. Commentaries Nitrated lipids: A class of cell-signaling molecules B. Kalyanaraman PMCID: PMC511014 The in and out of monocytes in atherosclerotic plaques: Balancing inflammation through migration Burkhard Ludewig and Jon D. Laman PMCID: PMC511015 Physical Sciences Chemistry Inhibitor design by wrapping packing defects in HIV-1 proteins Ariel Fernández, Kristina Rogale, Ridgway Scott, and Harold A. Scheraga PMCID: PMC511032 Physics Evolvability is a selectable trait David J. Earl and Michael W. Deem PMCID: PMC511006 Tubular precipitation and redox gradients on a bubbling template David A. Stone and Raymond E. Goldstein PMCID: PMC511016 Biological Sciences Applied Biological Sciences High-throughput sensing and noninvasive imaging of protein nuclear transport by using reconstitution of split Renilla luciferase Sung Bae Kim, Takeaki Ozawa, Shigeaki Watanabe, and Yoshio Umezawa PMCID: PMC511017 Biochemistry Resolution of organelle docking and fusion kinetics in a cell-free assay Alexey J. Merz and William T. Wickner PMCID: PMC511018 Kinetic profiles of p300 occupancy in vivo predict common features of promoter structure and coactivator recruitment James L. Smith, Wendy J. Freebern, Irene Collins, Adriana De Siervi, Idalia Montano, Cynthia M. Haggerty, Markey C. McNutt, Wayne G. Butscher, Inna Dzekunova, David W. Petersen, Ernest Kawasaki, Juanita L. Merchant, and Kevin Gardner PMCID: PMC511019 Inhibition of apoptosis in acute promyelocytic leukemia cells leads to increases in levels of oxidized protein and LMP2 immunoproteasome Mohammed A. S. Khan, Hammou Oubrahim, and Earl R. Stadtman PMCID: PMC511020 De novo design of catalytic proteins J. Kaplan and W. F. DeGrado PMCID: PMC511021 Crystal structure of pyrogallol–phloroglucinol transhydroxylase, an Mo enzyme capable of intermolecular hydroxyl transfer between phenols Albrecht Messerschmidt, Holger Niessen, Dietmar Abt, Oliver Einsle, Bernhard Schink, and Peter M. H. Kroneck PMCID: PMC511022 From the Cover:
Red cell membrane and plasma linoleic acid nitration products: Synthesis, clinical identification, and quantitation Paul R. S. Baker, Francisco J. Schopfer, Scott Sweeney, and Bruce A. Freeman PMCID: PMC511023 Use of sequence duplication to engineer a ligand-triggered, long-distance molecular switch in T4 lysozyme Mohammad S. Yousef, Walter A. Baase, and Brian W. Matthews PMCID: PMC511024 Total chemical synthesis of N-myristoylated HIV-1 matrix protein p17: Structural and mechanistic implications of p17 myristoylation Zhibin Wu, Jerry Alexandratos, Bryan Ericksen, Jacek Lubkowski, Robert C. Gallo, and Wuyuan Lu PMCID: PMC511025 In vitro transcription system delineates the distinct roles of the coactivators pCAF and p300 during MyoD/E47-dependent transactivation F. Jeffrey Dilworth, Karen J. Seaver, Anna L. Fishburn, Steve L. Htet, and Stephen J. Tapscott PMCID: PMC511026 Coactivator AIB1 links estrogen receptor transcriptional activity and stability Wenlin Shao, Erika Krasnickas Keeton, Donald P. McDonnell, and Myles Brown PMCID: PMC511007 Biophysics Direct observation of RuvAB-catalyzed branch migration of single Holliday junctions Roee Amit, Opher Gileadi, and Joel Stavans PMCID: PMC511027 Single-molecule study of RuvAB-mediated Holliday-junction migration A. Dawid, V. Croquette, M. Grigoriev, and F. Heslot PMCID: PMC511028 A single-amino-acid lid renders a gas-tight compartment within a membrane-bound transporter Lina Salomonsson, Alex Lee, Robert B. Gennis, and Peter Brzezinski PMCID: PMC511029 Pauling and Corey's α-pleated sheet structure may define the prefibrillar amyloidogenic intermediate in amyloid disease Roger S. Armen, Mari L. DeMarco, Darwin O. V. Alonso, and Valerie Daggett PMCID: PMC511030 The structure of human parvovirus B19 Bärbel Kaufmann, Alan A. Simpson, and Michael G. Rossmann PMCID: PMC511008 Time-resolved energy transfer in DNA sequence detection using water-soluble conjugated polymers: The role of electrostatic and hydrophobic interactions Qing-Hua Xu, Brent S. Gaylord, Shu Wang, Guillermo C. Bazan, Daniel Moses, and Alan J. Heeger PMCID: PMC511031 Inhibitor design by wrapping packing defects in HIV-1 proteins Ariel Fernández, Kristina Rogale, Ridgway Scott, and Harold A. Scheraga PMCID: PMC511032 In different organisms, the mode of interaction between two signaling proteins is not necessarily conserved Sang-Youn Park, Bryan D. Beel, Melvin I. Simon, Alexandrine M. Bilwes, and Brian R. Crane PMCID: PMC511033 Cell Biology Lightoid and Claret: A rab GTPase and its putative guanine nucleotide exchange factor in biogenesis of Drosophila eye pigment granules Jinping Ma, Heide Plesken, Jessica E. Treisman, Irit Edelman-Novemsky, and Mindong Ren PMCID: PMC511034 Dose-dependent response of FGF-2 for lymphangiogenesis Lynn K. Chang, Guillermo Garcia-Cardeña, Filip Farnebo, Michael Fannon, Emy J. Chen, Catherine Butterfield, Marsha A. Moses, Richard C. Mulligan, Judah Folkman, and Arja Kaipainen PMCID: PMC511009 How cholesterol homeostasis is regulated by plasma membrane cholesterol in excess of phospholipids Yvonne Lange, Jin Ye, and Theodore L. Steck PMCID: PMC511035 Rpe65 Leu450Met variant is associated with reduced levels of the retinal pigment epithelium lipofuscin fluorophores A2E and iso-A2E So Ra Kim, Nathan Fishkin, Jian Kong, Koji Nakanishi, Rando Allikmets, and Janet R. Sparrow PMCID: PMC511036 Developmental Biology Crystal structure of Caenorhabditis elegans HER-1 and characterization of the interaction between HER-1 and TRA-2A Brent Y. Hamaoka, Charles E. Dann, III, Brian V. Geisbrecht, and Daniel J. Leahy PMCID: PMC511037 Ecology Competition among fishermen and fish causes the collapse of Barents Sea capelin Dag Ø Hjermann, Geir Ottersen, and Nils Chr. Stenseth PMCID: PMC511038 Environmental Sciences Air levels of carcinogenic polycyclic aromatic hydrocarbons after the World Trade Center disaster Joachim D. Pleil, Alan F. Vette, Brent A. Johnson, and Stephen M. Rappaport PMCID: PMC511010 Evolution Evolvability is a selectable trait David J. Earl and Michael W. Deem PMCID: PMC511006 Genetics Mapping of sudden infant death with dysgenesis of the testes syndrome (SIDDT) by a SNP genome scan and identification of TSPYL loss of function Erik G. Puffenberger, Diane Hu-Lince, Jennifer M. Parod, David W. Craig, Seth E. Dobrin, Andrew R. Conway, Elizabeth A. Donarum, Kevin A. Strauss, Travis Dunckley, Javier F. Cardenas, Kara R. Melmed, Courtney A. Wright, Winnie Liang, Phillip Stafford, C. Robert Flynn, D. Holmes Morton, and Dietrich A. Stephan PMCID: PMC511011 The mouse juvenile spermatogonial depletion (jsd) phenotype is due to a mutation in the X-derived retrogene, mUtp14b Jan Rohozinski and Colin E. Bishop PMCID: PMC511039 5′ Long serial analysis of gene expression (LongSAGE) and 3′ LongSAGE for transcriptome characterization and genome annotation Chia-Lin Wei, Patrick Ng, Kuo Ping Chiu, Chee Hong Wong, Chin Chin Ang, Leonard Lipovich, Edison T. Liu, and Yijun Ruan PMCID: PMC511040 The mouse kinome: Discovery and comparative genomics of all mouse protein kinases Sean Caenepeel, Glen Charydczak, Sucha Sudarsanam, Tony Hunter, and Gerard Manning PMCID: PMC511041 Recruitment of the ArgR/Mcm1p repressor is stimulated by the activator Gcn4p: A self-checking activation mechanism Sungpil Yoon, Chhabi K. Govind, Hongfang Qiu, Soon-ja Kim, Jinsheng Dong, and Alan G. Hinnebusch PMCID: PMC511042 Evolutionary genomics of ecological specialization Shaobin Zhong, Arkady Khodursky, Daniel E. Dykhuizen, and Antony M. Dean PMCID: PMC511043 From the Cover:
Breed distribution and history of canine mdr1-1Δ, a pharmacogenetic mutation that marks the emergence of breeds from the collie lineage Mark W. Neff, Kathryn R. Robertson, Aaron K. Wong, Noa Safra, Karl W. Broman, Montgomery Slatkin, Katrina L. Mealey, and Niels C. Pedersen PMCID: PMC511012 Immunology Peroxynitrite inhibition of Coxsackievirus infection by prevention of viral RNA entry Elizaveta Padalko, Tomokazu Ohnishi, Kenji Matsushita, Henry Sun, Karen Fox-Talbot, Clare Bao, William M. Baldwin, III, and Charles J. Lowenstein PMCID: PMC511044 Tapasin enhances MHC class I peptide presentation according to peptide half-life Mark Howarth, Anthony Williams, Anne B. Tolstrup, and Tim Elliott PMCID: PMC511045 Amelioration of proteolipid protein 139–151-induced encephalomyelitis in SJL mice by modified amino acid copolymers and their mechanisms Joel N. H. Stern, Zsolt Illés, Jayagopala Reddy, Derin B. Keskin, Eric Sheu, Masha Fridkis-Hareli, Hiroyuki Nishimura, Celia F. Brosnan, Laura Santambrogio, Vijay K. Kuchroo, and Jack L. Strominger PMCID: PMC511046 Modified amino acid copolymers suppress myelin basic protein 85–99-induced encephalomyelitis in humanized mice through different effects on T cells Zsolt Illés, Joel N. H. Stern, Jayagopala Reddy, Hanspeter Waldner, Marcin P. Mycko, Celia F. Brosnan, Stephan Ellmerich, Daniel M. Altmann, Laura Santambrogio, Jack L. Strominger, and Vijay K. Kuchroo PMCID: PMC511047 Medical Sciences MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias George Adrian Calin, Chang-Gong Liu, Cinzia Sevignani, Manuela Ferracin, Nadia Felli, Calin Dan Dumitru, Masayoshi Shimizu, Amelia Cimmino, Simona Zupo, Mariella Dono, Marie L. Dell'Aquila, Hansjuerg Alder, Laura Rassenti, Thomas J. Kipps, Florencia Bullrich, Massimo Negrini, and Carlo M. Croce PMCID: PMC511048 Hematopoietic cells and osteoblasts are derived from a common marrow progenitor after bone marrow transplantation Massimo Dominici, Colin Pritchard, John E. Garlits, Ted J. Hofmann, Derek A. Persons, and Edwin M. Horwitz PMCID: PMC511049 Advanced glycation endproduct (AGE) receptor 1 is a negative regulator of the inflammatory response to AGE in mesangial cells Changyong Lu, John Cijiang He, Weijing Cai, Huixian Liu, Li Zhu, and Helen Vlassara PMCID: PMC511050 In vivo identification of genes that modify ether-a-go-go-related gene activity in Caenorhabditis elegans may also affect human cardiac arrhythmia Christina I. Petersen, Toni R. McFarland, Svetlana Z. Stepanovic, Ping Yang, David J. Reiner, Kenshi Hayashi, Alfred L. George, Dan M. Roden, James H. Thomas, and Jeffrey R. Balser PMCID: PMC511051 From the Cover:
Emigration of monocyte-derived cells from atherosclerotic lesions characterizes regressive, but not progressive, plaques Jaime Llodrá, Véronique Angeli, Jianhua Liu, Eugene Trogan, Edward A. Fisher, and Gwendalyn J. Randolph PMCID: PMC511052 A proteomic approach for the discovery of protease substrates Andrew J. Bredemeyer, Renate M. Lewis, James P. Malone, Alan E. Davis, Julia Gross, R. Reid Townsend, and Timothy J. Ley PMCID: PMC511053 Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: Prevention of reperfusion injury Riccardo Bertini, Marcello Allegretti, Cinzia Bizzarri, Alessio Moriconi, Massimo Locati, Giuseppe Zampella, Maria N. Cervellera, Vito Di Cioccio, Maria C. Cesta, Emanuela Galliera, Fernando O. Martinez, Rosa Di Bitondo, Giulia Troiani, Vilma Sabbatini, Gaetano D'Anniballe, Roberto Anacardio, Juan C. Cutrin, Barbara Cavalieri, Fabrizio Mainiero, Raffaele Strippoli, Pia Villa, Maria Di Girolamo, Franck Martin, Marco Gentile, Angela Santoni, Daniela Corda, Giuseppe Poli, Alberto Mantovani, Pietro Ghezzi, and Francesco Colotta PMCID: PMC511013 N-acetylation of hypothalamic α-melanocyte-stimulating hormone and regulation by leptin Li Guo, Heike Münzberg, Ronald C. Stuart, Eduardo A. Nillni, and Christian Bjørbæk PMCID: PMC511054 An antiproliferative factor from interstitial cystitis patients is a frizzled 8 protein-related sialoglycopeptide Susan K. Keay, Zoltan Szekely, Thomas P. Conrads, Timothy D. Veenstra, Joseph J. Barchi, Jr., Chen-Ou Zhang, Kristopher R. Koch, and Christopher J. Michejda PMCID: PMC511055 Genome-wide discovery of loci influencing chemotherapy cytotoxicity James W. Watters, Aldi Kraja, Melissa A. Meucci, Michael A. Province, and Howard L. McLeod PMCID: PMC511056 Microbiology Marek's disease virus-encoded Meq gene is involved in transformation of lymphocytes but is dispensable for replication Blanca Lupiani, Lucy F. Lee, Xiaoping Cui, Isabel Gimeno, Amy Anderson, Robin W. Morgan, Robert F. Silva, Richard L. Witter, Hsing-Jien Kung, and Sanjay M. Reddy PMCID: PMC511057 Targeting cell division: Small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality Danielle N. Margalit, Laura Romberg, Rebecca B. Mets, Alan M. Hebert, Timothy J. Mitchison, Marc W. Kirschner, and Debabrata RayChaudhuri PMCID: PMC511058 TRIM5α mediates the postentry block to N-tropic murine leukemia viruses in human cells Michel J. Perron, Matthew Stremlau, Byeongwoon Song, Wes Ulm, Richard C. Mulligan, and Joseph Sodroski PMCID: PMC511059 Genome-wide molecular dissection of serotype M3 group A Streptococcus strains causing two epidemics of invasive infections Stephen B. Beres, Gail L. Sylva, Daniel E. Sturdevant, Chanel N. Granville, Mengyao Liu, Stacy M. Ricklefs, Adeline R. Whitney, Larye D. Parkins, Nancy P. Hoe, Gerald J. Adams, Donald E. Low, Frank R. DeLeo, Allison McGeer, and James M. Musser PMCID: PMC511060 Neuroscience Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex S. Kelly, T. M. Bliss, A. K. Shah, G. H. Sun, M. Ma, W. C. Foo, J. Masel, M. A. Yenari, I. L. Weissman, N. Uchida, T. Palmer, and G. K. Steinberg PMCID: PMC511061 Genes encoding candidate pheromone receptors in a moth (Heliothis virescens) J. Krieger, E. Grosse-Wilde, T. Gohl, Y. M. E. Dewer, K. Raming, and H. Breer PMCID: PMC511062 Glucocorticoid receptor overexpression in forebrain: A mouse model of increased emotional lability Qiang Wei, Xin-Yun Lu, Li Liu, Gwen Schafer, Kun-Ruey Shieh, Sharon Burke, Terry E. Robinson, Stanley J. Watson, Audrey F. Seasholtz, and Huda Akil PMCID: PMC511063 Slow wave sleep in crayfish Fidel Ramón, Jesús Hernández-Falcón, Bao Nguyen, and Theodore H. Bullock PMCID: PMC511064 Persistent tetrodotoxin-sensitive sodium current resulting from U-to-C RNA editing of an insect sodium channel Zhiqi Liu, Weizhong Song, and Ke Dong PMCID: PMC511065 Ca2+/calmodulin-dependent protein kinase II potentiates ATP responses by promoting trafficking of P2X receptors Guang-Yin Xu and Li-Yen Mae Huang PMCID: PMC511066 Rhodopsin kinase activity modulates the amplitude of the visual response in Drosophila Seung-Jae Lee, Hong Xu, and Craig Montell PMCID: PMC511067 Physiology Multiprotein complex containing succinate dehydrogenase confers mitochondrial ATP-sensitive K+ channel activity Hossein Ardehali, Zhenhui Chen, Young Ko, Rafael Mejía-Alvarez, and Eduardo Marbán PMCID: PMC511068 The kinase Grk2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na+ channels Anuwat Dinudom, Andrew B. Fotia, Robert J. Lefkowitz, John A. Young, Sharad Kumar, and David I. Cook PMCID: PMC511069 The inhibitory effect of anandamide on luteinizing hormone-releasing hormone secretion is reversed by estrogen Camila Scorticati, Javier Fernández-Solari, Andrea De Laurentiis, Claudia Mohn, Juan P. Prestifilippo, Mercedes Lasaga, Adriana Seilicovich, Silvia Billi, Ana Franchi, Samuel M. McCann, and Valeria Rettori PMCID: PMC511070 Distinct stoichiometry of BKCa channel tetramer phosphorylation specifies channel activation and inhibition by cAMP-dependent protein kinase Lijun Tian, Lorraine S. Coghill, Heather McClafferty, Stephen H.-F. MacDonald, Ferenc A. Antoni, Peter Ruth, Hans-Guenther Knaus, and Michael J. Shipston PMCID: PMC511071 Plant Biology Specific and differential inhibition of very-long-chain fatty acid elongases from Arabidopsis thaliana by different herbicides Sandra Trenkamp, William Martin, and Klaus Tietjen PMCID: PMC511072 Psychology Eshkol–Wachman movement notation in diagnosis: The early detection of Asperger's syndrome Osnat Teitelbaum, Tom Benton, Prithvi K. Shah, Andrea Prince, Joseph L. Kelly, and Philip Teitelbaum PMCID: PMC511073 |
