Mechanism and evolution of protein dimerization.

Subunit asymmetry in the three-dimensional structure of a human CuZnSOD mutant found in familial amyotrophic lateral sclerosis.

Structures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: molecular basis of isozyme-drug discrimination.

Crystal structures of the psychrophilic alpha-amylase from Alteromonas haloplanctis in its native form and complexed with an inhibitor.

Solvation studies of DMP323 and A76928 bound to HIV protease: analysis of water sites using grand canonical Monte Carlo simulations.

Crystallization of phycoerythrin 545 of Rhodomonas lens using detergents and unusual additives.

A proposed architecture for lecithin cholesterol acyl transferase (LCAT): identification of the catalytic triad and molecular modeling.

Cadmium-induced crystallization of proteins: II. Crystallization of the Salmonella typhimurium histidine-binding protein in complex with L-histidine, L-arginine, or L-lysine.

Comparisons between the structures of HCV and Rep helicases reveal structural similarities between SF1 and SF2 super-families of helicases.

X-ray structures of three interface mutants of gammaB-crystallin from bovine eye lens.

Solution structure of Compstatin, a potent complement inhibitor.

Mutational analysis of human DNase I at the DNA binding interface: implications for DNA recognition, catalysis, and metal ion dependence.

Role of the amino-terminal region of streptokinase in the generation of a fully functional plasminogen activator complex probed with synthetic peptides.

Locally accessible conformations of proteins: multiple molecular dynamics simulations of crambin.

Spider minor ampullate silk proteins contain new repetitive sequences and highly conserved non-silk-like "spacer regions".

Tetramer-dimer equilibrium of oxyhemoglobin mutants determined from auto-oxidation rates.

The methanol-induced transition and the expanded helical conformation in hen lysozyme.

Anion binding to the ubiquitin molecule.

Serial increase in the thermal stability of 3-isopropylmalate dehydrogenase from Bacillus subtilis by experimental evolution.

High throughput protein characterization by automated reverse-phase chromatography/electrospray tandem mass spectrometry.

Motional dynamics of residues in a beta-hairpin peptide measured by 13C-NMR relaxation.

Multiple catalytic roles of His 287 of Rhodospirillum rubrum ribulose 1,5-bisphosphate carboxylase/oxygenase.

Determinants of protein hydrogen exchange studied in equine cytochrome c.

Structural and functional characterization of recombinant human cellular retinaldehyde-binding protein.

Mass spectrometric analysis of integral membrane proteins: application to complete mapping of bacteriorhodopsins and rhodopsin.

Context-dependent protein stabilization by methionine-to-leucine substitution shown in T4 lysozyme.

Crystal structure of glycosylasparaginase from Flavobacterium meningosepticum.

The N-terminal segment of antithrombin acts as a steric gate for the binding of heparin.

Tautomeric state and pKa of the phosphorylated active site histidine in the N-terminal domain of enzyme I of the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system.

S100B(betabeta) inhibits the protein kinase C-dependent phosphorylation of a peptide derived from p53 in a Ca2+-dependent manner.

A golden era for understanding enzyme mechanisms.